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What is Carisoprodol
CarisoprodolThe Generic name of this drug
Treatment SummaryCarisoprodol is a muscle relaxant prescribed to relieve pain in muscles and bones. It is usually taken as a pill, but can also be combined with aspirin or codeine. In 2012, it was classified as a Schedule IV drug in some US states because it was being abused at high rates, even though it has a low potential for abuse and dependence.
Somais the brand name
Carisoprodol Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Soma
Carisoprodol
1959
193
Approved as Treatment by the FDA
Carisoprodol, also called Soma, is approved by the FDA for 3 uses which include Musculoskeletal Diseases and Acute Pain .Musculoskeletal Diseases
Helps manage Musculoskeletal Disorders
Acute Pain
Helps manage Pain, Acute
Acute Coryza
Used to treat acute Discomfort in combination with Acetylsalicylic acid
Effectiveness
How Carisoprodol Affects PatientsCarisoprodol is a muscle relaxant that works by targeting the central nervous system (CNS). It helps to relieve the pain caused by muscle spasms. A breakdown product of carisoprodol, meprobamate, has calming and sleep-inducing effects. Clinical studies have shown that this drug can impair how a person performs on mental and physical tests.
How Carisoprodol works in the bodyThe exact way carisoprodol works to reduce muscle pain is not known. Animal studies suggest that it changes the activity between neurons in the spinal cord and the brain. It is also thought to have potential for abuse because it can change the way a certain type of brain receptor works. This alters the flow of neurotransmitters and can have a calming effect.
When to interrupt dosage
The recommended measure of Carisoprodol is based on the diagnosed state, including Acute Pain, Acute Coryza and Musculoskeletal Diseases. The quantity of dosage is contingent upon the method of delivery (e.g. Tablet, film coated - Oral or Oral) stated in the table below.Condition
Dosage
Administration
Musculoskeletal Diseases
, 350.0 mg, 250.0 mg, 200.0 mg
, Oral, Tablet - Oral, Tablet, Kit, Tablet, film coated, Tablet, film coated - Oral
Acute Pain
, 350.0 mg, 250.0 mg, 200.0 mg
, Oral, Tablet - Oral, Tablet, Kit, Tablet, film coated, Tablet, film coated - Oral
Acute Coryza
, 350.0 mg, 250.0 mg, 200.0 mg
, Oral, Tablet - Oral, Tablet, Kit, Tablet, film coated, Tablet, film coated - Oral
Warnings
Carisoprodol ContraindicationsCondition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Carisoprodol may interact with Pulse Frequency
Acute Coryza
Do Not Combine
Disorders of Porphyrin Metabolism
Do Not Combine
Common Carisoprodol Drug Interactions
Drug Name
Risk Level
Description
Azelastine
Major
Carisoprodol may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Ethanol
Major
Carisoprodol may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Oliceridine
Major
The risk or severity of hypotension, sedation, death, somnolence, and respiratory depression can be increased when Carisoprodol is combined with Oliceridine.
Thalidomide
Major
Carisoprodol may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
(R)-warfarin
Moderate
The metabolism of (R)-warfarin can be decreased when combined with Carisoprodol.
Carisoprodol Toxicity & Overdose RiskThe toxic dose of carisoprodol for rats when given intravenously or intraperitoneally is 450 mg/kg and 1,320 mg/kg when taken orally. In mice, these numbers are 165 mg/kg, 980 mg/kg, and 2,340 mg/kg respectively. Overdosing on carisoprodol can lead to a coma, shock, breathing problems, seizures, and death in extreme cases. Other symptoms may include dizziness, blurred vision, fast heartbeat, low blood pressure, confusion, hallucinations, and muscle stiffness. Alcohol or other drugs that depress the central nervous system can increase the effects
Carisoprodol Novel Uses: Which Conditions Have a Clinical Trial Featuring Carisoprodol?
23 active clinical trials are investigating the potential of Carisoprodol in providing relief from Acute Pain, Acute Coryza and Musculoskeletal Diseases.Condition
Clinical Trials
Trial Phases
Acute Coryza
0 Actively Recruiting
Musculoskeletal Diseases
4 Actively Recruiting
Phase 1, Phase 2, Not Applicable
Acute Pain
21 Actively Recruiting
Early Phase 1, Not Applicable, Phase 4, Phase 2, Phase 1
Carisoprodol Reviews: What are patients saying about Carisoprodol?
5Patient Review
11/20/2015 I've used this medication for about two decades to manage my MS-induced muscle spasms, and it's been incredibly effective. I have tried other muscle relaxants in the past, but none of them compare to this one. That said, it is difficult to wean yourself off of this medication after long-term use; you have to do it gradually.
5Patient Review
12/28/2015 I've been taking this medication for a decade and it's really helped me. I have severe lower back and neck pain, and after multiple surgeries (both fused spine segments and plates/pins), this is the only muscle relaxer that offers me consistent relief.
5Patient Review
11/27/2015 Carisoprodol was much more effective than Diazapam at relieving my muscle spasms without making me feel loopy.
5Patient Review
8/31/2016 I've been taking Soma for chronic pain that I've had for 16 years now. It's the only thing that helps.
5Patient Review
5/7/2016 This muscle relaxant is the only one that has helped me with my severe spasms. It's getting harder to find a physician who will prescribe it though, which is concerning.
5Patient Review
10/17/2018 I saw the best results when I took this medication as prescribed and with food.
5Patient Review
3/7/2015 This treatment is amazing! I can't believe how well it worked for me.
4.7Patient Review
12/31/20142Patient Review
10/6/2022 Do not drink alcohol or smoke cannabis while on this medication. I had one margarita and two puffs of a joint, and it almost killed me. I started to fade out while driving, and luckily was able to pull over before anything bad happened. My wife called 911 and was crying when they arrived because she thought I had died. So please, heed the warnings on the label and don't mix this drug with other substances!
1.7Patient Review
1/22/2016 I was only recently switched to this medication, but it seems to be working better than the last one. The downside is that it makes me sleepy very quickly, so I can only take it at night.
1.3Patient Review
2/19/2016 I have taken soma for 15 years and it has provided me a lot of relief. However, I got a refill that was CL 022 and it made me sleep walk and have weird dreams. I told the pharmacist that I never wanted this brand again and threw away most of my script.
Patient Q&A Section about carisoprodol
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is carisoprodol a painkiller?
"6 days ago"
Answered by AI
Does carisoprodol 350 mg make you sleepy?
"Carisoprodol can make you feel drowsy and lightheaded. Do not drive or operate heavy machinery until you know how this medication affects you. Carisoprodol can be addictive and may lead to dependence."
Answered by AI
What is carisoprodol used for?
"This medicine is used to relax muscles and relieve discomfort caused by acute, painful muscle or bone conditions. However, it is not a replacement for rest, exercise, physical therapy, or other treatments that your doctor may recommend for your medical condition."
Answered by AI