What is Cancidas
CaspofunginThe Generic name of this drug
Treatment SummaryCaspofungin, also known by its brand name Cancidas, is a type of antifungal drug used to treat fungal infections. It is typically administered through an intravenous injection and works by blocking the fungal cell wall from creating β(1,3)-D-Glucan. Caspofungin is most commonly used to treat infections caused by Aspergillus and Candida.
Cancidasis the brand name
Cancidas Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Cancidas
Caspofungin
2001
22
Approved as Treatment by the FDA
Caspofungin, also known as Cancidas, is approved by the FDA for 9 uses including Therapeutic procedure and Invasive Aspergillosis .Therapeutic procedure
Invasive Aspergillosis
Esophageal Candidiasis
Yeast Infection
Communicable Diseases
Candidemia
Abscess, Intra-Abdominal
Febrile Neutropenia
Peritonitis
Effectiveness
How Cancidas Affects PatientsCaspofungin is a type of antifungal medication used to treat infections caused by Aspergillus and Candida fungi. It works by preventing the fungi from forming its cell wall, which helps stop the infection from spreading. Although there is a chance that the fungi can become resistant to the drug, there has not been any research showing that this has happened with Caspofungin.
How Cancidas works in the bodyCaspofungin inhibits the formation of beta-(1,3)-D-glucan, a kind of molecule only found in certain fungi. This molecule is necessary for the fungi's cell wall, so blocking its production weakens the cell and helps kill the fungus. The drug targets the enzyme that produces this molecule.
When to interrupt dosage
The proposed portion of Cancidas is contingent upon the diagnosed state, such as Abscess, Intra-Abdominal, Therapeutic procedure and Invasive Aspergillosis. The amount of dosage is contingent upon the method of delivery (e.g. Powder, for solution - Intravenous or Injection, powder, for solution - Intravenous) indicated in the table below.Condition
Dosage
Administration
Abscess, Intra-Abdominal
5.0 mg/mL, 7.0 mg/mL, , 70.0 mg, 50.0 mg
Powder, for solution - Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Powder, for solution, Intravenous, Injection, powder, lyophilized, for solution, , Injection, powder, for solution, Injection - Intravenous, Injection
Therapeutic procedure
5.0 mg/mL, 7.0 mg/mL, , 70.0 mg, 50.0 mg
Powder, for solution - Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Powder, for solution, Intravenous, Injection, powder, lyophilized, for solution, , Injection, powder, for solution, Injection - Intravenous, Injection
Invasive Aspergillosis
5.0 mg/mL, 7.0 mg/mL, , 70.0 mg, 50.0 mg
Powder, for solution - Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Powder, for solution, Intravenous, Injection, powder, lyophilized, for solution, , Injection, powder, for solution, Injection - Intravenous, Injection
Peritonitis
5.0 mg/mL, 7.0 mg/mL, , 70.0 mg, 50.0 mg
Powder, for solution - Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Powder, for solution, Intravenous, Injection, powder, lyophilized, for solution, , Injection, powder, for solution, Injection - Intravenous, Injection
Oropharyngeal Candidiasis
5.0 mg/mL, 7.0 mg/mL, , 70.0 mg, 50.0 mg
Powder, for solution - Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Powder, for solution, Intravenous, Injection, powder, lyophilized, for solution, , Injection, powder, for solution, Injection - Intravenous, Injection
Febrile Neutropenia
5.0 mg/mL, 7.0 mg/mL, , 70.0 mg, 50.0 mg
Powder, for solution - Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Powder, for solution, Intravenous, Injection, powder, lyophilized, for solution, , Injection, powder, for solution, Injection - Intravenous, Injection
Communicable Diseases
5.0 mg/mL, 7.0 mg/mL, , 70.0 mg, 50.0 mg
Powder, for solution - Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Powder, for solution, Intravenous, Injection, powder, lyophilized, for solution, , Injection, powder, for solution, Injection - Intravenous, Injection
Esophageal Candidiasis
5.0 mg/mL, 7.0 mg/mL, , 70.0 mg, 50.0 mg
Powder, for solution - Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Powder, for solution, Intravenous, Injection, powder, lyophilized, for solution, , Injection, powder, for solution, Injection - Intravenous, Injection
Infections, Fungal
5.0 mg/mL, 7.0 mg/mL, , 70.0 mg, 50.0 mg
Powder, for solution - Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Powder, for solution, Intravenous, Injection, powder, lyophilized, for solution, , Injection, powder, for solution, Injection - Intravenous, Injection
Candidemia
5.0 mg/mL, 7.0 mg/mL, , 70.0 mg, 50.0 mg
Powder, for solution - Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Powder, for solution, Intravenous, Injection, powder, lyophilized, for solution, , Injection, powder, for solution, Injection - Intravenous, Injection
Yeast Infection
5.0 mg/mL, 7.0 mg/mL, , 70.0 mg, 50.0 mg
Powder, for solution - Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Powder, for solution, Intravenous, Injection, powder, lyophilized, for solution, , Injection, powder, for solution, Injection - Intravenous, Injection
Warnings
There are 20 known major drug interactions with Cancidas.Common Cancidas Drug Interactions
Drug Name
Risk Level
Description
Revefenacin
Major
Caspofungin may decrease the excretion rate of Revefenacin which could result in a higher serum level.
Acyclovir
Minor
The excretion of Acyclovir can be decreased when combined with Caspofungin.
Adefovir dipivoxil
Minor
The excretion of Adefovir dipivoxil can be decreased when combined with Caspofungin.
Alprostadil
Minor
The excretion of Alprostadil can be decreased when combined with Caspofungin.
Ambrisentan
Minor
The excretion of Ambrisentan can be decreased when combined with Caspofungin.
Cancidas Toxicity & Overdose RiskPotential side effects of the drug include rash, swelling, and rarely, nausea.
Cancidas Novel Uses: Which Conditions Have a Clinical Trial Featuring Cancidas?
17 active trials are currently in process to investigate the potential of Cancidas in managing Peritonitis, Invasive Aspergillosis and Esophageal Candidiasis.Condition
Clinical Trials
Trial Phases
Infections, Fungal
1 Actively Recruiting
Phase 3
Therapeutic procedure
0 Actively Recruiting
Peritonitis
1 Actively Recruiting
Not Applicable
Invasive Aspergillosis
2 Actively Recruiting
Phase 2, Phase 3
Esophageal Candidiasis
0 Actively Recruiting
Yeast Infection
7 Actively Recruiting
Phase 1, Phase 2, Phase 3, Early Phase 1, Not Applicable
Communicable Diseases
0 Actively Recruiting
Febrile Neutropenia
2 Actively Recruiting
Phase 2, Phase 4
Candidemia
4 Actively Recruiting
Phase 3, Phase 2, Not Applicable
Abscess, Intra-Abdominal
0 Actively Recruiting
Oropharyngeal Candidiasis
0 Actively Recruiting
Cancidas Reviews: What are patients saying about Cancidas?
4.7Patient Review
10/22/2010 I was able to effectively treat my wife's yeast infection with this medication. The short shelf life is really the only downside, but other than that it wasn't any worse than any other medication she's taken.
3.7Patient Review
11/22/2008 I was in and out of the hospital for six months with a really serious case of aspergillosis. This medicine saved my life with very few side effects, which is saying a lot considering I was also dealing with tuberculosis and pneumocystis at the time.
Patient Q&A Section about cancidas
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is Cancidas used for?
"Cancidas is a medication used to treat fungal infections in the stomach, lungs, esophagus, or other internal body areas. It may be used alone or with other medications."
Answered by AI
What is caspofungin used for?
"Caspofungin is used to treat serious fungal infections, including candidemia, esophageal candidiasis, other candida infections, and aspergillosis."
Answered by AI
Is caspofungin an antibiotic?
"Caspofungin acetate is an antifungal antibiotic that inhibits the growth of fungi by preventing the synthesis of 1,3-β-d-glucan, an essential component of the fungal cell wall. While caspofungin is effective against yeasts and dimorphic fungi such as Candida albicans, its effect on Aspergillus fumigatus is less well understood."
Answered by AI
What is micafungin used to treat?
"Micafungin is an antifungal medication used to treat serious fungal infections such as candidemia, acute disseminated candidiasis, candida peritonitis, and esophageal candidiasis."
Answered by AI