Brilinta

Thrombosis, Acute Chest Syndrome, Transient Ischemic Attack (TIA) + 8 more
Treatment
20 Active Studies for Brilinta

What is Brilinta

TicagrelorThe Generic name of this drug
Treatment SummaryTicagrelor (also known as AZD6140) is a medication used to prevent the formation of blood clots in patients with acute coronary syndrome or a history of heart attack. It was first described in 2003 and is marketed under the brand names Brilinta (US) and Brilique or Possia (EU). Ticagrelor was approved by the EMA in 2010 and by the FDA in 2011.
Brilintais the brand name
image of different drug pills on a surface
Brilinta Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Brilinta
Ticagrelor
2011
7

Effectiveness

How Brilinta Affects PatientsTicagrelor is a drug that helps prevent heart attacks and strokes by stopping blood clots from forming. It needs to be taken twice a day and is generally well-tolerated, but patients need to be aware of the potential side effects such as bleeding, difficulty breathing, and slower heart rate.
How Brilinta works in the bodyTicagrelor helps prevent blood clots by blocking a receptor that is involved in the formation of clots. It stops this receptor from communicating with other proteins which help create clotting. This reduces the risk of heart attack and stroke by preventing blood clots from forming.

When to interrupt dosage

The suggested dosage of Brilinta is contingent upon the diagnosed condition, including Stent Placement, Heart Attack and Stroke. The amount of dosage hinges on the method of delivery, as featured in the table below.
Condition
Dosage
Administration
High Ischemic Risk
, 90.0 mg, 60.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating
Stroke
, 90.0 mg, 60.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating
Thrombosis
, 90.0 mg, 60.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating
Acute Chest Syndrome
, 90.0 mg, 60.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating
Transient Ischemic Attack (TIA)
, 90.0 mg, 60.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating
Coronary Disease
, 90.0 mg, 60.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating
Heart Attack
, 90.0 mg, 60.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating
High Risk
, 90.0 mg, 60.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating
Cardiovascular Mortality
, 90.0 mg, 60.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating
Ischemic Stroke
, 90.0 mg, 60.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating
Stent Stenosis
, 90.0 mg, 60.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating

Warnings

Brilinta Contraindications
Condition
Risk Level
Notes
Intracranial Hemorrhage
Do Not Combine
Hemorrhage
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Ticagrelor may interact with Pulse Frequency
There are 20 known major drug interactions with Brilinta.
Common Brilinta Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The serum concentration of Abemaciclib can be increased when it is combined with Ticagrelor.
Abrocitinib
Major
The risk or severity of bleeding and thrombocytopenia can be increased when Ticagrelor is combined with Abrocitinib.
Acalabrutinib
Major
The metabolism of Acalabrutinib can be decreased when combined with Ticagrelor.
Albutrepenonacog alfa
Major
The therapeutic efficacy of Albutrepenonacog alfa can be decreased when used in combination with Ticagrelor.
Alectinib
Major
The metabolism of Alectinib can be decreased when combined with Ticagrelor.
Brilinta Toxicity & Overdose RiskSigns of ticagrelor overdose include bleeding, nausea, vomiting, diarrhea, and pauses in the heartbeat. Treatment for an overdose includes monitoring the patient's heart rate and providing supportive care. Due to it being protein bound, dialysis is not expected to remove ticagrelor from the blood.
image of a doctor in a lab doing drug, clinical research

Brilinta Novel Uses: Which Conditions Have a Clinical Trial Featuring Brilinta?

84 active clinical trials are investigating the efficacy of Brilinta in providing Acute Chest Syndrome, Cardiovascular Mortality and Myocardial Infarction relief.
Condition
Clinical Trials
Trial Phases
Cardiovascular Mortality
0 Actively Recruiting
Acute Chest Syndrome
3 Actively Recruiting
Not Applicable, Phase 2
High Risk
1 Actively Recruiting
Phase 1
Thrombosis
0 Actively Recruiting
Transient Ischemic Attack (TIA)
2 Actively Recruiting
Phase 4, Not Applicable
Coronary Disease
1 Actively Recruiting
Not Applicable
Heart Attack
26 Actively Recruiting
Not Applicable, Phase 4, Phase 1, Phase 2, Early Phase 1, Phase 3
Stent Stenosis
0 Actively Recruiting
High Ischemic Risk
0 Actively Recruiting
Stroke
9 Actively Recruiting
Phase 4, Phase 1, Not Applicable
Ischemic Stroke
21 Actively Recruiting
Phase 2, Phase 3, Not Applicable, Phase 1

Brilinta Reviews: What are patients saying about Brilinta?

4.3Patient Review
7/23/2019
Brilinta for Treatment to Prevent a Blood Clot in a Vascular Stent
I experienced shortness of breath, bruising, and epistaxis while taking this medication.
4Patient Review
12/28/2021
Brilinta for Blood Clot Prevention Following Percutaneous Coronary Intervention
I had a CABG surgery an year ago, Dr. prescribed Brilinta and is still on it, no major complaints. Experienced muscle twitching and elevation of BP a couple of times. I don't know if it is a side effect of Brilinta. Leading a normal life so far and taking one day at a time.
3.3Patient Review
4/1/2020
Brilinta for Treatment to Prevent a Blood Clot in a Vascular Stent
I've been feeling dizzy and short of breath since I got a stent placed two months ago. Not sure if it's the combination of this medication and losartan, but I'm going to give it a few more months before I make any decisions.
3Patient Review
3/3/2020
Brilinta for Blood Clot Prevention Following Percutaneous Coronary Intervention
I took this drug for 8 months and experienced nose bleeds, easy bruising, and difficulty urinating after 2 months. My cardiologist switched me to another anti coagulant and ALL these symptoms went away within one week.
2.3Patient Review
12/28/2019
Brilinta for Blood Clot Prevention Following Percutaneous Coronary Intervention
I had a stent put in on October 15th, and since then I've been having shortness of breath, confusion, unexplained depression and obsessive thoughts.
View All Reviews
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Patient Q&A Section about brilinta

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What kind of drug is Brilinta?

"BRILINTA can help prevent you from having another heart attack when taken with a low-dose aspirin. BRILINTA is more effective when aspirin is also taken, up to a maximum of 100 mg."

Answered by AI

Is Brilinta a blood thinner or antiplatelet?

"Brilinta is a blood thinner that can help prevent heart attack or stroke. However, it can also cause severe bleeding. In people who have had a previous heart attack, Brilinta can lower the risk of death from another heart attack."

Answered by AI

Is Brilinta the same as Plavix?

"Brilinta (ticagrelor) seems to be more effective than Plavix (clopidogrel) in reducing the percentage of CV death, MI or stroke in the first year of treatment. Brilinta patients more commonly reported breathing difficulties as a side effect compared to Plavix patients."

Answered by AI

What is Brilinta used for?

"Brilinta is a prescription medication used to reduce the risk of death, heart attack, and stroke in adults with a blocked blood flow to the heart or a history of heart attack."

Answered by AI

What are the major side effects of Brilinta?

"There is a chance of developing some of the following side effects after taking ibuprofen: bruising, bleeding more easily, nosebleeds, headache, dizziness, cough, nausea, and diarrhea."

Answered by AI

Clinical Trials for Brilinta

Have you considered Brilinta clinical trials? We made a collection of clinical trials featuring Brilinta, we think they might fit your search criteria.
Have you considered Brilinta clinical trials? We made a collection of clinical trials featuring Brilinta, we think they might fit your search criteria.
Have you considered Brilinta clinical trials? We made a collection of clinical trials featuring Brilinta, we think they might fit your search criteria.
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