What is Bijuva
EstradiolThe Generic name of this drug
Treatment SummaryEstradiol is a hormone produced naturally in female bodies. It is available in various forms as a hormone therapy to treat conditions caused by low estrogen levels, such as hot flashes and vaginal dryness. It can be taken orally as a pill, injected, used as a vaginal ring, patch, spray, gel, or cream. When taken orally or by injection, it is usually combined with a pro-drug ester. Ethinyl estradiol is a synthetic version of estradiol that is commonly used in combination with other hormones in birth control pills. It is more effective than estradiol because it is more bioavailable and
Estradermis the brand name
Bijuva Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Estraderm
Estradiol
1986
358
Approved as Treatment by the FDA
Estradiol, also known as Estraderm, is approved by the FDA for 4 uses like Breast Cancer and Palliative Treatment .Breast Cancer
Palliative Treatment
Birth Control
Used to treat Contraception in combination with Levonorgestrel
Hormonal Contraception
Used to treat Hormonal Contraception therapy in combination with Levonorgestrel
Effectiveness
How Bijuva Affects PatientsEstradiol is used to treat hot flashes, vaginal dryness, and other urogenital symptoms. It can also help increase bone density, improve the levels of certain proteins and hormones in the blood, and reduce the amount of follicle-stimulating hormones. However, it can increase the risk of developing cardiovascular disease, blood clots, and stroke. It also causes a hyper-coagulable state and can lead to increased levels of sodium in the body, which can cause hypertension.
How Bijuva works in the bodyEstrogen is naturally produced in the ovaries of adult women. After menopause, the majority of estrogen is created in the body from androstenedione, a hormone produced by the adrenal cortex. Estrogen works by binding to two types of receptors, ERα and ERβ, as well as GPER, which helps control its rapid effects. Once bound, estrogen enters the cell's nucleus and changes gene expression, which leads to the relief of postmenopausal symptoms like hot flashes, chills, sleep problems, and more.
When to interrupt dosage
The recommended measure of Bijuva is contingent upon the recognized condition, including Premature Menopause, Pharmaceutical Preparations and Postmenopause. The dosage fluctuates in line with the administration method depicted in the table beneath.Condition
Dosage
Administration
Postmenopausal Osteoporosis
, 0.00052 mg/mg, 0.005 mg/hour, 0.0005 mg/mg, 0.0006 mg/mg, 0.5 mg, 6.0 mg, 0.00375 mg/hour, 12.5 mg, 15.0 mg, 10.0 mg, 0.0075 mg/hour, 1.0 mg, 25.0 mg, 18.0 mg, 8.0 mg, 3.28 mg, 6.56 mg, 0.01 mg/hour, 8.66 mg, 0.0001 mg/mg, 0.0025 mg/hour, 0.00125 mg/mg, 0.025 mg, 0.01 mg, 0.00075 mg/mg, 0.06 %, 4.0 mg, 0.004 mg, 0.0075 mg/mg, 0.001 mg/mg, 1.5 mg, 2.0 mg, 0.0025 mg/mg, 0.005 mg/mg, 0.00025 mg/mg, 4.4 mg, 1.53 mg, 4.33 mg, 0.62 mg, 0.006 mg/hour, 0.00005 mg/mg, 40.0 mg/mL, 0.0014 mg/hour, 0.097 mg/[USP'U], 0.146 mg/[USP'U], 0.194 mg/[USP'U], 0.01 mg/[USP'U], 5.0 mg/mL, 20.0 mg, 22.0 mg, 0.1 %, 5.0 mg, 0.0045 mg/hour, 0.0052 mg/mg, 0.05 mg, 20.0 mg/mL, 10.0 mg/mL, 2.17 mg, 0.51 mg, 0.45 mg, 6.57 mg, 2.5 mg/mL, 1.8 mg, 0.9 mg, 4.84 mg, 14.0 mg, 4.95 mg, 50.0 mg
Transdermal, , Tablet, film coated, Insert - Vaginal, Tablet - Oral, Patch, extended release - Transdermal, Patch - Transdermal, Patch, Oral, Oral; Transdermal, Capsule; Kit, Vaginal, Patch, extended release, Tablet, Kit; Tablet - Oral, Insert, Gel - Transdermal, Topical, Spray, Cream - Vaginal, Capsule, Gel, Capsule; Spray, metered, Capsule; Kit - Oral, Tablet, film coated - Oral, Kit; Tablet, Film, extended release, Gel - Topical, Gel, metered, Ring - Vaginal, Spray - Transdermal, Tablet - Vaginal, Emulsion - Topical, Cream, Pellet - Oral, Pellet, Film, extended release - Transdermal, Capsule; Spray, metered - Oral; Transdermal, Emulsion, Lotion - Topical, Capsule - Oral, Gel, metered - Topical, Tablet, film coated - Vaginal, Spray, metered, Spray, metered - Transdermal, Ring, Gel, metered - Transdermal, Injection - Intramuscular, Intramuscular, Cream - Transdermal, Pellet, implantable - Subcutaneous, Injection, solution - Intramuscular, Pellet, implantable
Hypogonadism
, 0.00052 mg/mg, 0.005 mg/hour, 0.0005 mg/mg, 0.0006 mg/mg, 0.5 mg, 6.0 mg, 0.00375 mg/hour, 12.5 mg, 15.0 mg, 10.0 mg, 0.0075 mg/hour, 1.0 mg, 25.0 mg, 18.0 mg, 8.0 mg, 3.28 mg, 6.56 mg, 0.01 mg/hour, 8.66 mg, 0.0001 mg/mg, 0.0025 mg/hour, 0.00125 mg/mg, 0.025 mg, 0.01 mg, 0.00075 mg/mg, 0.06 %, 4.0 mg, 0.004 mg, 0.0075 mg/mg, 0.001 mg/mg, 1.5 mg, 2.0 mg, 0.0025 mg/mg, 0.005 mg/mg, 0.00025 mg/mg, 4.4 mg, 1.53 mg, 4.33 mg, 0.62 mg, 0.006 mg/hour, 0.00005 mg/mg, 40.0 mg/mL, 0.0014 mg/hour, 0.097 mg/[USP'U], 0.146 mg/[USP'U], 0.194 mg/[USP'U], 0.01 mg/[USP'U], 5.0 mg/mL, 20.0 mg, 22.0 mg, 0.1 %, 5.0 mg, 0.0045 mg/hour, 0.0052 mg/mg, 0.05 mg, 20.0 mg/mL, 10.0 mg/mL, 2.17 mg, 0.51 mg, 0.45 mg, 6.57 mg, 2.5 mg/mL, 1.8 mg, 0.9 mg, 4.84 mg, 14.0 mg, 4.95 mg, 50.0 mg
Transdermal, , Tablet, film coated, Insert - Vaginal, Tablet - Oral, Patch, extended release - Transdermal, Patch - Transdermal, Patch, Oral, Oral; Transdermal, Capsule; Kit, Vaginal, Patch, extended release, Tablet, Kit; Tablet - Oral, Insert, Gel - Transdermal, Topical, Spray, Cream - Vaginal, Capsule, Gel, Capsule; Spray, metered, Capsule; Kit - Oral, Tablet, film coated - Oral, Kit; Tablet, Film, extended release, Gel - Topical, Gel, metered, Ring - Vaginal, Spray - Transdermal, Tablet - Vaginal, Emulsion - Topical, Cream, Pellet - Oral, Pellet, Film, extended release - Transdermal, Capsule; Spray, metered - Oral; Transdermal, Emulsion, Lotion - Topical, Capsule - Oral, Gel, metered - Topical, Tablet, film coated - Vaginal, Spray, metered, Spray, metered - Transdermal, Ring, Gel, metered - Transdermal, Injection - Intramuscular, Intramuscular, Cream - Transdermal, Pellet, implantable - Subcutaneous, Injection, solution - Intramuscular, Pellet, implantable
Atrophic
, 0.00052 mg/mg, 0.005 mg/hour, 0.0005 mg/mg, 0.0006 mg/mg, 0.5 mg, 6.0 mg, 0.00375 mg/hour, 12.5 mg, 15.0 mg, 10.0 mg, 0.0075 mg/hour, 1.0 mg, 25.0 mg, 18.0 mg, 8.0 mg, 3.28 mg, 6.56 mg, 0.01 mg/hour, 8.66 mg, 0.0001 mg/mg, 0.0025 mg/hour, 0.00125 mg/mg, 0.025 mg, 0.01 mg, 0.00075 mg/mg, 0.06 %, 4.0 mg, 0.004 mg, 0.0075 mg/mg, 0.001 mg/mg, 1.5 mg, 2.0 mg, 0.0025 mg/mg, 0.005 mg/mg, 0.00025 mg/mg, 4.4 mg, 1.53 mg, 4.33 mg, 0.62 mg, 0.006 mg/hour, 0.00005 mg/mg, 40.0 mg/mL, 0.0014 mg/hour, 0.097 mg/[USP'U], 0.146 mg/[USP'U], 0.194 mg/[USP'U], 0.01 mg/[USP'U], 5.0 mg/mL, 20.0 mg, 22.0 mg, 0.1 %, 5.0 mg, 0.0045 mg/hour, 0.0052 mg/mg, 0.05 mg, 20.0 mg/mL, 10.0 mg/mL, 2.17 mg, 0.51 mg, 0.45 mg, 6.57 mg, 2.5 mg/mL, 1.8 mg, 0.9 mg, 4.84 mg, 14.0 mg, 4.95 mg, 50.0 mg
Transdermal, , Tablet, film coated, Insert - Vaginal, Tablet - Oral, Patch, extended release - Transdermal, Patch - Transdermal, Patch, Oral, Oral; Transdermal, Capsule; Kit, Vaginal, Patch, extended release, Tablet, Kit; Tablet - Oral, Insert, Gel - Transdermal, Topical, Spray, Cream - Vaginal, Capsule, Gel, Capsule; Spray, metered, Capsule; Kit - Oral, Tablet, film coated - Oral, Kit; Tablet, Film, extended release, Gel - Topical, Gel, metered, Ring - Vaginal, Spray - Transdermal, Tablet - Vaginal, Emulsion - Topical, Cream, Pellet - Oral, Pellet, Film, extended release - Transdermal, Capsule; Spray, metered - Oral; Transdermal, Emulsion, Lotion - Topical, Capsule - Oral, Gel, metered - Topical, Tablet, film coated - Vaginal, Spray, metered, Spray, metered - Transdermal, Ring, Gel, metered - Transdermal, Injection - Intramuscular, Intramuscular, Cream - Transdermal, Pellet, implantable - Subcutaneous, Injection, solution - Intramuscular, Pellet, implantable
Prostate Cancer
, 0.00052 mg/mg, 0.005 mg/hour, 0.0005 mg/mg, 0.0006 mg/mg, 0.5 mg, 6.0 mg, 0.00375 mg/hour, 12.5 mg, 15.0 mg, 10.0 mg, 0.0075 mg/hour, 1.0 mg, 25.0 mg, 18.0 mg, 8.0 mg, 3.28 mg, 6.56 mg, 0.01 mg/hour, 8.66 mg, 0.0001 mg/mg, 0.0025 mg/hour, 0.00125 mg/mg, 0.025 mg, 0.01 mg, 0.00075 mg/mg, 0.06 %, 4.0 mg, 0.004 mg, 0.0075 mg/mg, 0.001 mg/mg, 1.5 mg, 2.0 mg, 0.0025 mg/mg, 0.005 mg/mg, 0.00025 mg/mg, 4.4 mg, 1.53 mg, 4.33 mg, 0.62 mg, 0.006 mg/hour, 0.00005 mg/mg, 40.0 mg/mL, 0.0014 mg/hour, 0.097 mg/[USP'U], 0.146 mg/[USP'U], 0.194 mg/[USP'U], 0.01 mg/[USP'U], 5.0 mg/mL, 20.0 mg, 22.0 mg, 0.1 %, 5.0 mg, 0.0045 mg/hour, 0.0052 mg/mg, 0.05 mg, 20.0 mg/mL, 10.0 mg/mL, 2.17 mg, 0.51 mg, 0.45 mg, 6.57 mg, 2.5 mg/mL, 1.8 mg, 0.9 mg, 4.84 mg, 14.0 mg, 4.95 mg, 50.0 mg
Transdermal, , Tablet, film coated, Insert - Vaginal, Tablet - Oral, Patch, extended release - Transdermal, Patch - Transdermal, Patch, Oral, Oral; Transdermal, Capsule; Kit, Vaginal, Patch, extended release, Tablet, Kit; Tablet - Oral, Insert, Gel - Transdermal, Topical, Spray, Cream - Vaginal, Capsule, Gel, Capsule; Spray, metered, Capsule; Kit - Oral, Tablet, film coated - Oral, Kit; Tablet, Film, extended release, Gel - Topical, Gel, metered, Ring - Vaginal, Spray - Transdermal, Tablet - Vaginal, Emulsion - Topical, Cream, Pellet - Oral, Pellet, Film, extended release - Transdermal, Capsule; Spray, metered - Oral; Transdermal, Emulsion, Lotion - Topical, Capsule - Oral, Gel, metered - Topical, Tablet, film coated - Vaginal, Spray, metered, Spray, metered - Transdermal, Ring, Gel, metered - Transdermal, Injection - Intramuscular, Intramuscular, Cream - Transdermal, Pellet, implantable - Subcutaneous, Injection, solution - Intramuscular, Pellet, implantable
Vasomotor System
, 0.00052 mg/mg, 0.005 mg/hour, 0.0005 mg/mg, 0.0006 mg/mg, 0.5 mg, 6.0 mg, 0.00375 mg/hour, 12.5 mg, 15.0 mg, 10.0 mg, 0.0075 mg/hour, 1.0 mg, 25.0 mg, 18.0 mg, 8.0 mg, 3.28 mg, 6.56 mg, 0.01 mg/hour, 8.66 mg, 0.0001 mg/mg, 0.0025 mg/hour, 0.00125 mg/mg, 0.025 mg, 0.01 mg, 0.00075 mg/mg, 0.06 %, 4.0 mg, 0.004 mg, 0.0075 mg/mg, 0.001 mg/mg, 1.5 mg, 2.0 mg, 0.0025 mg/mg, 0.005 mg/mg, 0.00025 mg/mg, 4.4 mg, 1.53 mg, 4.33 mg, 0.62 mg, 0.006 mg/hour, 0.00005 mg/mg, 40.0 mg/mL, 0.0014 mg/hour, 0.097 mg/[USP'U], 0.146 mg/[USP'U], 0.194 mg/[USP'U], 0.01 mg/[USP'U], 5.0 mg/mL, 20.0 mg, 22.0 mg, 0.1 %, 5.0 mg, 0.0045 mg/hour, 0.0052 mg/mg, 0.05 mg, 20.0 mg/mL, 10.0 mg/mL, 2.17 mg, 0.51 mg, 0.45 mg, 6.57 mg, 2.5 mg/mL, 1.8 mg, 0.9 mg, 4.84 mg, 14.0 mg, 4.95 mg, 50.0 mg
Transdermal, , Tablet, film coated, Insert - Vaginal, Tablet - Oral, Patch, extended release - Transdermal, Patch - Transdermal, Patch, Oral, Oral; Transdermal, Capsule; Kit, Vaginal, Patch, extended release, Tablet, Kit; Tablet - Oral, Insert, Gel - Transdermal, Topical, Spray, Cream - Vaginal, Capsule, Gel, Capsule; Spray, metered, Capsule; Kit - Oral, Tablet, film coated - Oral, Kit; Tablet, Film, extended release, Gel - Topical, Gel, metered, Ring - Vaginal, Spray - Transdermal, Tablet - Vaginal, Emulsion - Topical, Cream, Pellet - Oral, Pellet, Film, extended release - Transdermal, Capsule; Spray, metered - Oral; Transdermal, Emulsion, Lotion - Topical, Capsule - Oral, Gel, metered - Topical, Tablet, film coated - Vaginal, Spray, metered, Spray, metered - Transdermal, Ring, Gel, metered - Transdermal, Injection - Intramuscular, Intramuscular, Cream - Transdermal, Pellet, implantable - Subcutaneous, Injection, solution - Intramuscular, Pellet, implantable
female castration
, 0.00052 mg/mg, 0.005 mg/hour, 0.0005 mg/mg, 0.0006 mg/mg, 0.5 mg, 6.0 mg, 0.00375 mg/hour, 12.5 mg, 15.0 mg, 10.0 mg, 0.0075 mg/hour, 1.0 mg, 25.0 mg, 18.0 mg, 8.0 mg, 3.28 mg, 6.56 mg, 0.01 mg/hour, 8.66 mg, 0.0001 mg/mg, 0.0025 mg/hour, 0.00125 mg/mg, 0.025 mg, 0.01 mg, 0.00075 mg/mg, 0.06 %, 4.0 mg, 0.004 mg, 0.0075 mg/mg, 0.001 mg/mg, 1.5 mg, 2.0 mg, 0.0025 mg/mg, 0.005 mg/mg, 0.00025 mg/mg, 4.4 mg, 1.53 mg, 4.33 mg, 0.62 mg, 0.006 mg/hour, 0.00005 mg/mg, 40.0 mg/mL, 0.0014 mg/hour, 0.097 mg/[USP'U], 0.146 mg/[USP'U], 0.194 mg/[USP'U], 0.01 mg/[USP'U], 5.0 mg/mL, 20.0 mg, 22.0 mg, 0.1 %, 5.0 mg, 0.0045 mg/hour, 0.0052 mg/mg, 0.05 mg, 20.0 mg/mL, 10.0 mg/mL, 2.17 mg, 0.51 mg, 0.45 mg, 6.57 mg, 2.5 mg/mL, 1.8 mg, 0.9 mg, 4.84 mg, 14.0 mg, 4.95 mg, 50.0 mg
Transdermal, , Tablet, film coated, Insert - Vaginal, Tablet - Oral, Patch, extended release - Transdermal, Patch - Transdermal, Patch, Oral, Oral; Transdermal, Capsule; Kit, Vaginal, Patch, extended release, Tablet, Kit; Tablet - Oral, Insert, Gel - Transdermal, Topical, Spray, Cream - Vaginal, Capsule, Gel, Capsule; Spray, metered, Capsule; Kit - Oral, Tablet, film coated - Oral, Kit; Tablet, Film, extended release, Gel - Topical, Gel, metered, Ring - Vaginal, Spray - Transdermal, Tablet - Vaginal, Emulsion - Topical, Cream, Pellet - Oral, Pellet, Film, extended release - Transdermal, Capsule; Spray, metered - Oral; Transdermal, Emulsion, Lotion - Topical, Capsule - Oral, Gel, metered - Topical, Tablet, film coated - Vaginal, Spray, metered, Spray, metered - Transdermal, Ring, Gel, metered - Transdermal, Injection - Intramuscular, Intramuscular, Cream - Transdermal, Pellet, implantable - Subcutaneous, Injection, solution - Intramuscular, Pellet, implantable
Therapeutic procedure
, 0.00052 mg/mg, 0.005 mg/hour, 0.0005 mg/mg, 0.0006 mg/mg, 0.5 mg, 6.0 mg, 0.00375 mg/hour, 12.5 mg, 15.0 mg, 10.0 mg, 0.0075 mg/hour, 1.0 mg, 25.0 mg, 18.0 mg, 8.0 mg, 3.28 mg, 6.56 mg, 0.01 mg/hour, 8.66 mg, 0.0001 mg/mg, 0.0025 mg/hour, 0.00125 mg/mg, 0.025 mg, 0.01 mg, 0.00075 mg/mg, 0.06 %, 4.0 mg, 0.004 mg, 0.0075 mg/mg, 0.001 mg/mg, 1.5 mg, 2.0 mg, 0.0025 mg/mg, 0.005 mg/mg, 0.00025 mg/mg, 4.4 mg, 1.53 mg, 4.33 mg, 0.62 mg, 0.006 mg/hour, 0.00005 mg/mg, 40.0 mg/mL, 0.0014 mg/hour, 0.097 mg/[USP'U], 0.146 mg/[USP'U], 0.194 mg/[USP'U], 0.01 mg/[USP'U], 5.0 mg/mL, 20.0 mg, 22.0 mg, 0.1 %, 5.0 mg, 0.0045 mg/hour, 0.0052 mg/mg, 0.05 mg, 20.0 mg/mL, 10.0 mg/mL, 2.17 mg, 0.51 mg, 0.45 mg, 6.57 mg, 2.5 mg/mL, 1.8 mg, 0.9 mg, 4.84 mg, 14.0 mg, 4.95 mg, 50.0 mg
Transdermal, , Tablet, film coated, Insert - Vaginal, Tablet - Oral, Patch, extended release - Transdermal, Patch - Transdermal, Patch, Oral, Oral; Transdermal, Capsule; Kit, Vaginal, Patch, extended release, Tablet, Kit; Tablet - Oral, Insert, Gel - Transdermal, Topical, Spray, Cream - Vaginal, Capsule, Gel, Capsule; Spray, metered, Capsule; Kit - Oral, Tablet, film coated - Oral, Kit; Tablet, Film, extended release, Gel - Topical, Gel, metered, Ring - Vaginal, Spray - Transdermal, Tablet - Vaginal, Emulsion - Topical, Cream, Pellet - Oral, Pellet, Film, extended release - Transdermal, Capsule; Spray, metered - Oral; Transdermal, Emulsion, Lotion - Topical, Capsule - Oral, Gel, metered - Topical, Tablet, film coated - Vaginal, Spray, metered, Spray, metered - Transdermal, Ring, Gel, metered - Transdermal, Injection - Intramuscular, Intramuscular, Cream - Transdermal, Pellet, implantable - Subcutaneous, Injection, solution - Intramuscular, Pellet, implantable
Kraurosis Vulvae
, 0.00052 mg/mg, 0.005 mg/hour, 0.0005 mg/mg, 0.0006 mg/mg, 0.5 mg, 6.0 mg, 0.00375 mg/hour, 12.5 mg, 15.0 mg, 10.0 mg, 0.0075 mg/hour, 1.0 mg, 25.0 mg, 18.0 mg, 8.0 mg, 3.28 mg, 6.56 mg, 0.01 mg/hour, 8.66 mg, 0.0001 mg/mg, 0.0025 mg/hour, 0.00125 mg/mg, 0.025 mg, 0.01 mg, 0.00075 mg/mg, 0.06 %, 4.0 mg, 0.004 mg, 0.0075 mg/mg, 0.001 mg/mg, 1.5 mg, 2.0 mg, 0.0025 mg/mg, 0.005 mg/mg, 0.00025 mg/mg, 4.4 mg, 1.53 mg, 4.33 mg, 0.62 mg, 0.006 mg/hour, 0.00005 mg/mg, 40.0 mg/mL, 0.0014 mg/hour, 0.097 mg/[USP'U], 0.146 mg/[USP'U], 0.194 mg/[USP'U], 0.01 mg/[USP'U], 5.0 mg/mL, 20.0 mg, 22.0 mg, 0.1 %, 5.0 mg, 0.0045 mg/hour, 0.0052 mg/mg, 0.05 mg, 20.0 mg/mL, 10.0 mg/mL, 2.17 mg, 0.51 mg, 0.45 mg, 6.57 mg, 2.5 mg/mL, 1.8 mg, 0.9 mg, 4.84 mg, 14.0 mg, 4.95 mg, 50.0 mg
Transdermal, , Tablet, film coated, Insert - Vaginal, Tablet - Oral, Patch, extended release - Transdermal, Patch - Transdermal, Patch, Oral, Oral; Transdermal, Capsule; Kit, Vaginal, Patch, extended release, Tablet, Kit; Tablet - Oral, Insert, Gel - Transdermal, Topical, Spray, Cream - Vaginal, Capsule, Gel, Capsule; Spray, metered, Capsule; Kit - Oral, Tablet, film coated - Oral, Kit; Tablet, Film, extended release, Gel - Topical, Gel, metered, Ring - Vaginal, Spray - Transdermal, Tablet - Vaginal, Emulsion - Topical, Cream, Pellet - Oral, Pellet, Film, extended release - Transdermal, Capsule; Spray, metered - Oral; Transdermal, Emulsion, Lotion - Topical, Capsule - Oral, Gel, metered - Topical, Tablet, film coated - Vaginal, Spray, metered, Spray, metered - Transdermal, Ring, Gel, metered - Transdermal, Injection - Intramuscular, Intramuscular, Cream - Transdermal, Pellet, implantable - Subcutaneous, Injection, solution - Intramuscular, Pellet, implantable
Birth Control
, 0.00052 mg/mg, 0.005 mg/hour, 0.0005 mg/mg, 0.0006 mg/mg, 0.5 mg, 6.0 mg, 0.00375 mg/hour, 12.5 mg, 15.0 mg, 10.0 mg, 0.0075 mg/hour, 1.0 mg, 25.0 mg, 18.0 mg, 8.0 mg, 3.28 mg, 6.56 mg, 0.01 mg/hour, 8.66 mg, 0.0001 mg/mg, 0.0025 mg/hour, 0.00125 mg/mg, 0.025 mg, 0.01 mg, 0.00075 mg/mg, 0.06 %, 4.0 mg, 0.004 mg, 0.0075 mg/mg, 0.001 mg/mg, 1.5 mg, 2.0 mg, 0.0025 mg/mg, 0.005 mg/mg, 0.00025 mg/mg, 4.4 mg, 1.53 mg, 4.33 mg, 0.62 mg, 0.006 mg/hour, 0.00005 mg/mg, 40.0 mg/mL, 0.0014 mg/hour, 0.097 mg/[USP'U], 0.146 mg/[USP'U], 0.194 mg/[USP'U], 0.01 mg/[USP'U], 5.0 mg/mL, 20.0 mg, 22.0 mg, 0.1 %, 5.0 mg, 0.0045 mg/hour, 0.0052 mg/mg, 0.05 mg, 20.0 mg/mL, 10.0 mg/mL, 2.17 mg, 0.51 mg, 0.45 mg, 6.57 mg, 2.5 mg/mL, 1.8 mg, 0.9 mg, 4.84 mg, 14.0 mg, 4.95 mg, 50.0 mg
Transdermal, , Tablet, film coated, Insert - Vaginal, Tablet - Oral, Patch, extended release - Transdermal, Patch - Transdermal, Patch, Oral, Oral; Transdermal, Capsule; Kit, Vaginal, Patch, extended release, Tablet, Kit; Tablet - Oral, Insert, Gel - Transdermal, Topical, Spray, Cream - Vaginal, Capsule, Gel, Capsule; Spray, metered, Capsule; Kit - Oral, Tablet, film coated - Oral, Kit; Tablet, Film, extended release, Gel - Topical, Gel, metered, Ring - Vaginal, Spray - Transdermal, Tablet - Vaginal, Emulsion - Topical, Cream, Pellet - Oral, Pellet, Film, extended release - Transdermal, Capsule; Spray, metered - Oral; Transdermal, Emulsion, Lotion - Topical, Capsule - Oral, Gel, metered - Topical, Tablet, film coated - Vaginal, Spray, metered, Spray, metered - Transdermal, Ring, Gel, metered - Transdermal, Injection - Intramuscular, Intramuscular, Cream - Transdermal, Pellet, implantable - Subcutaneous, Injection, solution - Intramuscular, Pellet, implantable
Low Testosterone
, 0.00052 mg/mg, 0.005 mg/hour, 0.0005 mg/mg, 0.0006 mg/mg, 0.5 mg, 6.0 mg, 0.00375 mg/hour, 12.5 mg, 15.0 mg, 10.0 mg, 0.0075 mg/hour, 1.0 mg, 25.0 mg, 18.0 mg, 8.0 mg, 3.28 mg, 6.56 mg, 0.01 mg/hour, 8.66 mg, 0.0001 mg/mg, 0.0025 mg/hour, 0.00125 mg/mg, 0.025 mg, 0.01 mg, 0.00075 mg/mg, 0.06 %, 4.0 mg, 0.004 mg, 0.0075 mg/mg, 0.001 mg/mg, 1.5 mg, 2.0 mg, 0.0025 mg/mg, 0.005 mg/mg, 0.00025 mg/mg, 4.4 mg, 1.53 mg, 4.33 mg, 0.62 mg, 0.006 mg/hour, 0.00005 mg/mg, 40.0 mg/mL, 0.0014 mg/hour, 0.097 mg/[USP'U], 0.146 mg/[USP'U], 0.194 mg/[USP'U], 0.01 mg/[USP'U], 5.0 mg/mL, 20.0 mg, 22.0 mg, 0.1 %, 5.0 mg, 0.0045 mg/hour, 0.0052 mg/mg, 0.05 mg, 20.0 mg/mL, 10.0 mg/mL, 2.17 mg, 0.51 mg, 0.45 mg, 6.57 mg, 2.5 mg/mL, 1.8 mg, 0.9 mg, 4.84 mg, 14.0 mg, 4.95 mg, 50.0 mg
Transdermal, , Tablet, film coated, Insert - Vaginal, Tablet - Oral, Patch, extended release - Transdermal, Patch - Transdermal, Patch, Oral, Oral; Transdermal, Capsule; Kit, Vaginal, Patch, extended release, Tablet, Kit; Tablet - Oral, Insert, Gel - Transdermal, Topical, Spray, Cream - Vaginal, Capsule, Gel, Capsule; Spray, metered, Capsule; Kit - Oral, Tablet, film coated - Oral, Kit; Tablet, Film, extended release, Gel - Topical, Gel, metered, Ring - Vaginal, Spray - Transdermal, Tablet - Vaginal, Emulsion - Topical, Cream, Pellet - Oral, Pellet, Film, extended release - Transdermal, Capsule; Spray, metered - Oral; Transdermal, Emulsion, Lotion - Topical, Capsule - Oral, Gel, metered - Topical, Tablet, film coated - Vaginal, Spray, metered, Spray, metered - Transdermal, Ring, Gel, metered - Transdermal, Injection - Intramuscular, Intramuscular, Cream - Transdermal, Pellet, implantable - Subcutaneous, Injection, solution - Intramuscular, Pellet, implantable
Hot flashes
, 0.00052 mg/mg, 0.005 mg/hour, 0.0005 mg/mg, 0.0006 mg/mg, 0.5 mg, 6.0 mg, 0.00375 mg/hour, 12.5 mg, 15.0 mg, 10.0 mg, 0.0075 mg/hour, 1.0 mg, 25.0 mg, 18.0 mg, 8.0 mg, 3.28 mg, 6.56 mg, 0.01 mg/hour, 8.66 mg, 0.0001 mg/mg, 0.0025 mg/hour, 0.00125 mg/mg, 0.025 mg, 0.01 mg, 0.00075 mg/mg, 0.06 %, 4.0 mg, 0.004 mg, 0.0075 mg/mg, 0.001 mg/mg, 1.5 mg, 2.0 mg, 0.0025 mg/mg, 0.005 mg/mg, 0.00025 mg/mg, 4.4 mg, 1.53 mg, 4.33 mg, 0.62 mg, 0.006 mg/hour, 0.00005 mg/mg, 40.0 mg/mL, 0.0014 mg/hour, 0.097 mg/[USP'U], 0.146 mg/[USP'U], 0.194 mg/[USP'U], 0.01 mg/[USP'U], 5.0 mg/mL, 20.0 mg, 22.0 mg, 0.1 %, 5.0 mg, 0.0045 mg/hour, 0.0052 mg/mg, 0.05 mg, 20.0 mg/mL, 10.0 mg/mL, 2.17 mg, 0.51 mg, 0.45 mg, 6.57 mg, 2.5 mg/mL, 1.8 mg, 0.9 mg, 4.84 mg, 14.0 mg, 4.95 mg, 50.0 mg
Transdermal, , Tablet, film coated, Insert - Vaginal, Tablet - Oral, Patch, extended release - Transdermal, Patch - Transdermal, Patch, Oral, Oral; Transdermal, Capsule; Kit, Vaginal, Patch, extended release, Tablet, Kit; Tablet - Oral, Insert, Gel - Transdermal, Topical, Spray, Cream - Vaginal, Capsule, Gel, Capsule; Spray, metered, Capsule; Kit - Oral, Tablet, film coated - Oral, Kit; Tablet, Film, extended release, Gel - Topical, Gel, metered, Ring - Vaginal, Spray - Transdermal, Tablet - Vaginal, Emulsion - Topical, Cream, Pellet - Oral, Pellet, Film, extended release - Transdermal, Capsule; Spray, metered - Oral; Transdermal, Emulsion, Lotion - Topical, Capsule - Oral, Gel, metered - Topical, Tablet, film coated - Vaginal, Spray, metered, Spray, metered - Transdermal, Ring, Gel, metered - Transdermal, Injection - Intramuscular, Intramuscular, Cream - Transdermal, Pellet, implantable - Subcutaneous, Injection, solution - Intramuscular, Pellet, implantable
Vasomotor Symptoms Associated With Menopause
, 0.00052 mg/mg, 0.005 mg/hour, 0.0005 mg/mg, 0.0006 mg/mg, 0.5 mg, 6.0 mg, 0.00375 mg/hour, 12.5 mg, 15.0 mg, 10.0 mg, 0.0075 mg/hour, 1.0 mg, 25.0 mg, 18.0 mg, 8.0 mg, 3.28 mg, 6.56 mg, 0.01 mg/hour, 8.66 mg, 0.0001 mg/mg, 0.0025 mg/hour, 0.00125 mg/mg, 0.025 mg, 0.01 mg, 0.00075 mg/mg, 0.06 %, 4.0 mg, 0.004 mg, 0.0075 mg/mg, 0.001 mg/mg, 1.5 mg, 2.0 mg, 0.0025 mg/mg, 0.005 mg/mg, 0.00025 mg/mg, 4.4 mg, 1.53 mg, 4.33 mg, 0.62 mg, 0.006 mg/hour, 0.00005 mg/mg, 40.0 mg/mL, 0.0014 mg/hour, 0.097 mg/[USP'U], 0.146 mg/[USP'U], 0.194 mg/[USP'U], 0.01 mg/[USP'U], 5.0 mg/mL, 20.0 mg, 22.0 mg, 0.1 %, 5.0 mg, 0.0045 mg/hour, 0.0052 mg/mg, 0.05 mg, 20.0 mg/mL, 10.0 mg/mL, 2.17 mg, 0.51 mg, 0.45 mg, 6.57 mg, 2.5 mg/mL, 1.8 mg, 0.9 mg, 4.84 mg, 14.0 mg, 4.95 mg, 50.0 mg
Transdermal, , Tablet, film coated, Insert - Vaginal, Tablet - Oral, Patch, extended release - Transdermal, Patch - Transdermal, Patch, Oral, Oral; Transdermal, Capsule; Kit, Vaginal, Patch, extended release, Tablet, Kit; Tablet - Oral, Insert, Gel - Transdermal, Topical, Spray, Cream - Vaginal, Capsule, Gel, Capsule; Spray, metered, Capsule; Kit - Oral, Tablet, film coated - Oral, Kit; Tablet, Film, extended release, Gel - Topical, Gel, metered, Ring - Vaginal, Spray - Transdermal, Tablet - Vaginal, Emulsion - Topical, Cream, Pellet - Oral, Pellet, Film, extended release - Transdermal, Capsule; Spray, metered - Oral; Transdermal, Emulsion, Lotion - Topical, Capsule - Oral, Gel, metered - Topical, Tablet, film coated - Vaginal, Spray, metered, Spray, metered - Transdermal, Ring, Gel, metered - Transdermal, Injection - Intramuscular, Intramuscular, Cream - Transdermal, Pellet, implantable - Subcutaneous, Injection, solution - Intramuscular, Pellet, implantable
hypoestrogenism
, 0.00052 mg/mg, 0.005 mg/hour, 0.0005 mg/mg, 0.0006 mg/mg, 0.5 mg, 6.0 mg, 0.00375 mg/hour, 12.5 mg, 15.0 mg, 10.0 mg, 0.0075 mg/hour, 1.0 mg, 25.0 mg, 18.0 mg, 8.0 mg, 3.28 mg, 6.56 mg, 0.01 mg/hour, 8.66 mg, 0.0001 mg/mg, 0.0025 mg/hour, 0.00125 mg/mg, 0.025 mg, 0.01 mg, 0.00075 mg/mg, 0.06 %, 4.0 mg, 0.004 mg, 0.0075 mg/mg, 0.001 mg/mg, 1.5 mg, 2.0 mg, 0.0025 mg/mg, 0.005 mg/mg, 0.00025 mg/mg, 4.4 mg, 1.53 mg, 4.33 mg, 0.62 mg, 0.006 mg/hour, 0.00005 mg/mg, 40.0 mg/mL, 0.0014 mg/hour, 0.097 mg/[USP'U], 0.146 mg/[USP'U], 0.194 mg/[USP'U], 0.01 mg/[USP'U], 5.0 mg/mL, 20.0 mg, 22.0 mg, 0.1 %, 5.0 mg, 0.0045 mg/hour, 0.0052 mg/mg, 0.05 mg, 20.0 mg/mL, 10.0 mg/mL, 2.17 mg, 0.51 mg, 0.45 mg, 6.57 mg, 2.5 mg/mL, 1.8 mg, 0.9 mg, 4.84 mg, 14.0 mg, 4.95 mg, 50.0 mg
Transdermal, , Tablet, film coated, Insert - Vaginal, Tablet - Oral, Patch, extended release - Transdermal, Patch - Transdermal, Patch, Oral, Oral; Transdermal, Capsule; Kit, Vaginal, Patch, extended release, Tablet, Kit; Tablet - Oral, Insert, Gel - Transdermal, Topical, Spray, Cream - Vaginal, Capsule, Gel, Capsule; Spray, metered, Capsule; Kit - Oral, Tablet, film coated - Oral, Kit; Tablet, Film, extended release, Gel - Topical, Gel, metered, Ring - Vaginal, Spray - Transdermal, Tablet - Vaginal, Emulsion - Topical, Cream, Pellet - Oral, Pellet, Film, extended release - Transdermal, Capsule; Spray, metered - Oral; Transdermal, Emulsion, Lotion - Topical, Capsule - Oral, Gel, metered - Topical, Tablet, film coated - Vaginal, Spray, metered, Spray, metered - Transdermal, Ring, Gel, metered - Transdermal, Injection - Intramuscular, Intramuscular, Cream - Transdermal, Pellet, implantable - Subcutaneous, Injection, solution - Intramuscular, Pellet, implantable
advanced androgen dependent Prostate cancer
, 0.00052 mg/mg, 0.005 mg/hour, 0.0005 mg/mg, 0.0006 mg/mg, 0.5 mg, 6.0 mg, 0.00375 mg/hour, 12.5 mg, 15.0 mg, 10.0 mg, 0.0075 mg/hour, 1.0 mg, 25.0 mg, 18.0 mg, 8.0 mg, 3.28 mg, 6.56 mg, 0.01 mg/hour, 8.66 mg, 0.0001 mg/mg, 0.0025 mg/hour, 0.00125 mg/mg, 0.025 mg, 0.01 mg, 0.00075 mg/mg, 0.06 %, 4.0 mg, 0.004 mg, 0.0075 mg/mg, 0.001 mg/mg, 1.5 mg, 2.0 mg, 0.0025 mg/mg, 0.005 mg/mg, 0.00025 mg/mg, 4.4 mg, 1.53 mg, 4.33 mg, 0.62 mg, 0.006 mg/hour, 0.00005 mg/mg, 40.0 mg/mL, 0.0014 mg/hour, 0.097 mg/[USP'U], 0.146 mg/[USP'U], 0.194 mg/[USP'U], 0.01 mg/[USP'U], 5.0 mg/mL, 20.0 mg, 22.0 mg, 0.1 %, 5.0 mg, 0.0045 mg/hour, 0.0052 mg/mg, 0.05 mg, 20.0 mg/mL, 10.0 mg/mL, 2.17 mg, 0.51 mg, 0.45 mg, 6.57 mg, 2.5 mg/mL, 1.8 mg, 0.9 mg, 4.84 mg, 14.0 mg, 4.95 mg, 50.0 mg
Transdermal, , Tablet, film coated, Insert - Vaginal, Tablet - Oral, Patch, extended release - Transdermal, Patch - Transdermal, Patch, Oral, Oral; Transdermal, Capsule; Kit, Vaginal, Patch, extended release, Tablet, Kit; Tablet - Oral, Insert, Gel - Transdermal, Topical, Spray, Cream - Vaginal, Capsule, Gel, Capsule; Spray, metered, Capsule; Kit - Oral, Tablet, film coated - Oral, Kit; Tablet, Film, extended release, Gel - Topical, Gel, metered, Ring - Vaginal, Spray - Transdermal, Tablet - Vaginal, Emulsion - Topical, Cream, Pellet - Oral, Pellet, Film, extended release - Transdermal, Capsule; Spray, metered - Oral; Transdermal, Emulsion, Lotion - Topical, Capsule - Oral, Gel, metered - Topical, Tablet, film coated - Vaginal, Spray, metered, Spray, metered - Transdermal, Ring, Gel, metered - Transdermal, Injection - Intramuscular, Intramuscular, Cream - Transdermal, Pellet, implantable - Subcutaneous, Injection, solution - Intramuscular, Pellet, implantable
Postmenopause
, 0.00052 mg/mg, 0.005 mg/hour, 0.0005 mg/mg, 0.0006 mg/mg, 0.5 mg, 6.0 mg, 0.00375 mg/hour, 12.5 mg, 15.0 mg, 10.0 mg, 0.0075 mg/hour, 1.0 mg, 25.0 mg, 18.0 mg, 8.0 mg, 3.28 mg, 6.56 mg, 0.01 mg/hour, 8.66 mg, 0.0001 mg/mg, 0.0025 mg/hour, 0.00125 mg/mg, 0.025 mg, 0.01 mg, 0.00075 mg/mg, 0.06 %, 4.0 mg, 0.004 mg, 0.0075 mg/mg, 0.001 mg/mg, 1.5 mg, 2.0 mg, 0.0025 mg/mg, 0.005 mg/mg, 0.00025 mg/mg, 4.4 mg, 1.53 mg, 4.33 mg, 0.62 mg, 0.006 mg/hour, 0.00005 mg/mg, 40.0 mg/mL, 0.0014 mg/hour, 0.097 mg/[USP'U], 0.146 mg/[USP'U], 0.194 mg/[USP'U], 0.01 mg/[USP'U], 5.0 mg/mL, 20.0 mg, 22.0 mg, 0.1 %, 5.0 mg, 0.0045 mg/hour, 0.0052 mg/mg, 0.05 mg, 20.0 mg/mL, 10.0 mg/mL, 2.17 mg, 0.51 mg, 0.45 mg, 6.57 mg, 2.5 mg/mL, 1.8 mg, 0.9 mg, 4.84 mg, 14.0 mg, 4.95 mg, 50.0 mg
Transdermal, , Tablet, film coated, Insert - Vaginal, Tablet - Oral, Patch, extended release - Transdermal, Patch - Transdermal, Patch, Oral, Oral; Transdermal, Capsule; Kit, Vaginal, Patch, extended release, Tablet, Kit; Tablet - Oral, Insert, Gel - Transdermal, Topical, Spray, Cream - Vaginal, Capsule, Gel, Capsule; Spray, metered, Capsule; Kit - Oral, Tablet, film coated - Oral, Kit; Tablet, Film, extended release, Gel - Topical, Gel, metered, Ring - Vaginal, Spray - Transdermal, Tablet - Vaginal, Emulsion - Topical, Cream, Pellet - Oral, Pellet, Film, extended release - Transdermal, Capsule; Spray, metered - Oral; Transdermal, Emulsion, Lotion - Topical, Capsule - Oral, Gel, metered - Topical, Tablet, film coated - Vaginal, Spray, metered, Spray, metered - Transdermal, Ring, Gel, metered - Transdermal, Injection - Intramuscular, Intramuscular, Cream - Transdermal, Pellet, implantable - Subcutaneous, Injection, solution - Intramuscular, Pellet, implantable
Hormonal Contraception
, 0.00052 mg/mg, 0.005 mg/hour, 0.0005 mg/mg, 0.0006 mg/mg, 0.5 mg, 6.0 mg, 0.00375 mg/hour, 12.5 mg, 15.0 mg, 10.0 mg, 0.0075 mg/hour, 1.0 mg, 25.0 mg, 18.0 mg, 8.0 mg, 3.28 mg, 6.56 mg, 0.01 mg/hour, 8.66 mg, 0.0001 mg/mg, 0.0025 mg/hour, 0.00125 mg/mg, 0.025 mg, 0.01 mg, 0.00075 mg/mg, 0.06 %, 4.0 mg, 0.004 mg, 0.0075 mg/mg, 0.001 mg/mg, 1.5 mg, 2.0 mg, 0.0025 mg/mg, 0.005 mg/mg, 0.00025 mg/mg, 4.4 mg, 1.53 mg, 4.33 mg, 0.62 mg, 0.006 mg/hour, 0.00005 mg/mg, 40.0 mg/mL, 0.0014 mg/hour, 0.097 mg/[USP'U], 0.146 mg/[USP'U], 0.194 mg/[USP'U], 0.01 mg/[USP'U], 5.0 mg/mL, 20.0 mg, 22.0 mg, 0.1 %, 5.0 mg, 0.0045 mg/hour, 0.0052 mg/mg, 0.05 mg, 20.0 mg/mL, 10.0 mg/mL, 2.17 mg, 0.51 mg, 0.45 mg, 6.57 mg, 2.5 mg/mL, 1.8 mg, 0.9 mg, 4.84 mg, 14.0 mg, 4.95 mg, 50.0 mg
Transdermal, , Tablet, film coated, Insert - Vaginal, Tablet - Oral, Patch, extended release - Transdermal, Patch - Transdermal, Patch, Oral, Oral; Transdermal, Capsule; Kit, Vaginal, Patch, extended release, Tablet, Kit; Tablet - Oral, Insert, Gel - Transdermal, Topical, Spray, Cream - Vaginal, Capsule, Gel, Capsule; Spray, metered, Capsule; Kit - Oral, Tablet, film coated - Oral, Kit; Tablet, Film, extended release, Gel - Topical, Gel, metered, Ring - Vaginal, Spray - Transdermal, Tablet - Vaginal, Emulsion - Topical, Cream, Pellet - Oral, Pellet, Film, extended release - Transdermal, Capsule; Spray, metered - Oral; Transdermal, Emulsion, Lotion - Topical, Capsule - Oral, Gel, metered - Topical, Tablet, film coated - Vaginal, Spray, metered, Spray, metered - Transdermal, Ring, Gel, metered - Transdermal, Injection - Intramuscular, Intramuscular, Cream - Transdermal, Pellet, implantable - Subcutaneous, Injection, solution - Intramuscular, Pellet, implantable
estradiol
, 0.00052 mg/mg, 0.005 mg/hour, 0.0005 mg/mg, 0.0006 mg/mg, 0.5 mg, 6.0 mg, 0.00375 mg/hour, 12.5 mg, 15.0 mg, 10.0 mg, 0.0075 mg/hour, 1.0 mg, 25.0 mg, 18.0 mg, 8.0 mg, 3.28 mg, 6.56 mg, 0.01 mg/hour, 8.66 mg, 0.0001 mg/mg, 0.0025 mg/hour, 0.00125 mg/mg, 0.025 mg, 0.01 mg, 0.00075 mg/mg, 0.06 %, 4.0 mg, 0.004 mg, 0.0075 mg/mg, 0.001 mg/mg, 1.5 mg, 2.0 mg, 0.0025 mg/mg, 0.005 mg/mg, 0.00025 mg/mg, 4.4 mg, 1.53 mg, 4.33 mg, 0.62 mg, 0.006 mg/hour, 0.00005 mg/mg, 40.0 mg/mL, 0.0014 mg/hour, 0.097 mg/[USP'U], 0.146 mg/[USP'U], 0.194 mg/[USP'U], 0.01 mg/[USP'U], 5.0 mg/mL, 20.0 mg, 22.0 mg, 0.1 %, 5.0 mg, 0.0045 mg/hour, 0.0052 mg/mg, 0.05 mg, 20.0 mg/mL, 10.0 mg/mL, 2.17 mg, 0.51 mg, 0.45 mg, 6.57 mg, 2.5 mg/mL, 1.8 mg, 0.9 mg, 4.84 mg, 14.0 mg, 4.95 mg, 50.0 mg
Transdermal, , Tablet, film coated, Insert - Vaginal, Tablet - Oral, Patch, extended release - Transdermal, Patch - Transdermal, Patch, Oral, Oral; Transdermal, Capsule; Kit, Vaginal, Patch, extended release, Tablet, Kit; Tablet - Oral, Insert, Gel - Transdermal, Topical, Spray, Cream - Vaginal, Capsule, Gel, Capsule; Spray, metered, Capsule; Kit - Oral, Tablet, film coated - Oral, Kit; Tablet, Film, extended release, Gel - Topical, Gel, metered, Ring - Vaginal, Spray - Transdermal, Tablet - Vaginal, Emulsion - Topical, Cream, Pellet - Oral, Pellet, Film, extended release - Transdermal, Capsule; Spray, metered - Oral; Transdermal, Emulsion, Lotion - Topical, Capsule - Oral, Gel, metered - Topical, Tablet, film coated - Vaginal, Spray, metered, Spray, metered - Transdermal, Ring, Gel, metered - Transdermal, Injection - Intramuscular, Intramuscular, Cream - Transdermal, Pellet, implantable - Subcutaneous, Injection, solution - Intramuscular, Pellet, implantable
Breast
, 0.00052 mg/mg, 0.005 mg/hour, 0.0005 mg/mg, 0.0006 mg/mg, 0.5 mg, 6.0 mg, 0.00375 mg/hour, 12.5 mg, 15.0 mg, 10.0 mg, 0.0075 mg/hour, 1.0 mg, 25.0 mg, 18.0 mg, 8.0 mg, 3.28 mg, 6.56 mg, 0.01 mg/hour, 8.66 mg, 0.0001 mg/mg, 0.0025 mg/hour, 0.00125 mg/mg, 0.025 mg, 0.01 mg, 0.00075 mg/mg, 0.06 %, 4.0 mg, 0.004 mg, 0.0075 mg/mg, 0.001 mg/mg, 1.5 mg, 2.0 mg, 0.0025 mg/mg, 0.005 mg/mg, 0.00025 mg/mg, 4.4 mg, 1.53 mg, 4.33 mg, 0.62 mg, 0.006 mg/hour, 0.00005 mg/mg, 40.0 mg/mL, 0.0014 mg/hour, 0.097 mg/[USP'U], 0.146 mg/[USP'U], 0.194 mg/[USP'U], 0.01 mg/[USP'U], 5.0 mg/mL, 20.0 mg, 22.0 mg, 0.1 %, 5.0 mg, 0.0045 mg/hour, 0.0052 mg/mg, 0.05 mg, 20.0 mg/mL, 10.0 mg/mL, 2.17 mg, 0.51 mg, 0.45 mg, 6.57 mg, 2.5 mg/mL, 1.8 mg, 0.9 mg, 4.84 mg, 14.0 mg, 4.95 mg, 50.0 mg
Transdermal, , Tablet, film coated, Insert - Vaginal, Tablet - Oral, Patch, extended release - Transdermal, Patch - Transdermal, Patch, Oral, Oral; Transdermal, Capsule; Kit, Vaginal, Patch, extended release, Tablet, Kit; Tablet - Oral, Insert, Gel - Transdermal, Topical, Spray, Cream - Vaginal, Capsule, Gel, Capsule; Spray, metered, Capsule; Kit - Oral, Tablet, film coated - Oral, Kit; Tablet, Film, extended release, Gel - Topical, Gel, metered, Ring - Vaginal, Spray - Transdermal, Tablet - Vaginal, Emulsion - Topical, Cream, Pellet - Oral, Pellet, Film, extended release - Transdermal, Capsule; Spray, metered - Oral; Transdermal, Emulsion, Lotion - Topical, Capsule - Oral, Gel, metered - Topical, Tablet, film coated - Vaginal, Spray, metered, Spray, metered - Transdermal, Ring, Gel, metered - Transdermal, Injection - Intramuscular, Intramuscular, Cream - Transdermal, Pellet, implantable - Subcutaneous, Injection, solution - Intramuscular, Pellet, implantable
no menstrual period in previous 6 months
, 0.00052 mg/mg, 0.005 mg/hour, 0.0005 mg/mg, 0.0006 mg/mg, 0.5 mg, 6.0 mg, 0.00375 mg/hour, 12.5 mg, 15.0 mg, 10.0 mg, 0.0075 mg/hour, 1.0 mg, 25.0 mg, 18.0 mg, 8.0 mg, 3.28 mg, 6.56 mg, 0.01 mg/hour, 8.66 mg, 0.0001 mg/mg, 0.0025 mg/hour, 0.00125 mg/mg, 0.025 mg, 0.01 mg, 0.00075 mg/mg, 0.06 %, 4.0 mg, 0.004 mg, 0.0075 mg/mg, 0.001 mg/mg, 1.5 mg, 2.0 mg, 0.0025 mg/mg, 0.005 mg/mg, 0.00025 mg/mg, 4.4 mg, 1.53 mg, 4.33 mg, 0.62 mg, 0.006 mg/hour, 0.00005 mg/mg, 40.0 mg/mL, 0.0014 mg/hour, 0.097 mg/[USP'U], 0.146 mg/[USP'U], 0.194 mg/[USP'U], 0.01 mg/[USP'U], 5.0 mg/mL, 20.0 mg, 22.0 mg, 0.1 %, 5.0 mg, 0.0045 mg/hour, 0.0052 mg/mg, 0.05 mg, 20.0 mg/mL, 10.0 mg/mL, 2.17 mg, 0.51 mg, 0.45 mg, 6.57 mg, 2.5 mg/mL, 1.8 mg, 0.9 mg, 4.84 mg, 14.0 mg, 4.95 mg, 50.0 mg
Transdermal, , Tablet, film coated, Insert - Vaginal, Tablet - Oral, Patch, extended release - Transdermal, Patch - Transdermal, Patch, Oral, Oral; Transdermal, Capsule; Kit, Vaginal, Patch, extended release, Tablet, Kit; Tablet - Oral, Insert, Gel - Transdermal, Topical, Spray, Cream - Vaginal, Capsule, Gel, Capsule; Spray, metered, Capsule; Kit - Oral, Tablet, film coated - Oral, Kit; Tablet, Film, extended release, Gel - Topical, Gel, metered, Ring - Vaginal, Spray - Transdermal, Tablet - Vaginal, Emulsion - Topical, Cream, Pellet - Oral, Pellet, Film, extended release - Transdermal, Capsule; Spray, metered - Oral; Transdermal, Emulsion, Lotion - Topical, Capsule - Oral, Gel, metered - Topical, Tablet, film coated - Vaginal, Spray, metered, Spray, metered - Transdermal, Ring, Gel, metered - Transdermal, Injection - Intramuscular, Intramuscular, Cream - Transdermal, Pellet, implantable - Subcutaneous, Injection, solution - Intramuscular, Pellet, implantable
Premature Menopause
, 0.00052 mg/mg, 0.005 mg/hour, 0.0005 mg/mg, 0.0006 mg/mg, 0.5 mg, 6.0 mg, 0.00375 mg/hour, 12.5 mg, 15.0 mg, 10.0 mg, 0.0075 mg/hour, 1.0 mg, 25.0 mg, 18.0 mg, 8.0 mg, 3.28 mg, 6.56 mg, 0.01 mg/hour, 8.66 mg, 0.0001 mg/mg, 0.0025 mg/hour, 0.00125 mg/mg, 0.025 mg, 0.01 mg, 0.00075 mg/mg, 0.06 %, 4.0 mg, 0.004 mg, 0.0075 mg/mg, 0.001 mg/mg, 1.5 mg, 2.0 mg, 0.0025 mg/mg, 0.005 mg/mg, 0.00025 mg/mg, 4.4 mg, 1.53 mg, 4.33 mg, 0.62 mg, 0.006 mg/hour, 0.00005 mg/mg, 40.0 mg/mL, 0.0014 mg/hour, 0.097 mg/[USP'U], 0.146 mg/[USP'U], 0.194 mg/[USP'U], 0.01 mg/[USP'U], 5.0 mg/mL, 20.0 mg, 22.0 mg, 0.1 %, 5.0 mg, 0.0045 mg/hour, 0.0052 mg/mg, 0.05 mg, 20.0 mg/mL, 10.0 mg/mL, 2.17 mg, 0.51 mg, 0.45 mg, 6.57 mg, 2.5 mg/mL, 1.8 mg, 0.9 mg, 4.84 mg, 14.0 mg, 4.95 mg, 50.0 mg
Transdermal, , Tablet, film coated, Insert - Vaginal, Tablet - Oral, Patch, extended release - Transdermal, Patch - Transdermal, Patch, Oral, Oral; Transdermal, Capsule; Kit, Vaginal, Patch, extended release, Tablet, Kit; Tablet - Oral, Insert, Gel - Transdermal, Topical, Spray, Cream - Vaginal, Capsule, Gel, Capsule; Spray, metered, Capsule; Kit - Oral, Tablet, film coated - Oral, Kit; Tablet, Film, extended release, Gel - Topical, Gel, metered, Ring - Vaginal, Spray - Transdermal, Tablet - Vaginal, Emulsion - Topical, Cream, Pellet - Oral, Pellet, Film, extended release - Transdermal, Capsule; Spray, metered - Oral; Transdermal, Emulsion, Lotion - Topical, Capsule - Oral, Gel, metered - Topical, Tablet, film coated - Vaginal, Spray, metered, Spray, metered - Transdermal, Ring, Gel, metered - Transdermal, Injection - Intramuscular, Intramuscular, Cream - Transdermal, Pellet, implantable - Subcutaneous, Injection, solution - Intramuscular, Pellet, implantable
Warnings
Bijuva ContraindicationsCondition
Risk Level
Notes
Deep Vein Thrombosis
Do Not Combine
Thromboembolism
Do Not Combine
Pulmonary Embolism
Do Not Combine
Thromboembolism
Do Not Combine
Neoplasms, Hormone-Dependent
Do Not Combine
undiagnosed abnormal genital bleeding
Do Not Combine
Liver Dysfunction
Do Not Combine
Thrombophilia
Do Not Combine
Breast
Do Not Combine
Breast
Do Not Combine
Angioedema
Do Not Combine
Breast Cancer
Do Not Combine
history of deep venous thrombosis
Do Not Combine
Pulmonary Embolism
Do Not Combine
Angioedema
Do Not Combine
estrogen-dependent neoplasia
Do Not Combine
suspected pregnancy
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Estradiol may interact with Toxoplasma Infections
Common Bijuva Drug Interactions
Drug Name
Risk Level
Description
Aminophylline
Major
The metabolism of Aminophylline can be decreased when combined with Estradiol.
Anagrelide
Major
The metabolism of Anagrelide can be decreased when combined with Estradiol.
Anastrozole
Major
The therapeutic efficacy of Anastrozole can be decreased when used in combination with Estradiol.
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Estradiol.
Axitinib
Major
The metabolism of Axitinib can be decreased when combined with Estradiol.
Bijuva Toxicity & Overdose RiskTests have shown that taking a small amount of estradiol every day over a 90 day period has no adverse effects. However, taking too much estradiol can lead to nausea, vomiting, abdominal pain, breast tenderness, blood clots, and vaginal bleeding. If someone has taken too much estradiol, it is recommended to stop taking it and provide supportive care.
Bijuva Novel Uses: Which Conditions Have a Clinical Trial Featuring Bijuva?
Currently, 867 active clinical trials are assessing the potential of Bijuva to address Osteoporosis, Amenorrhea of 6 months or longer duration and Urogenital Atrophy.Condition
Clinical Trials
Trial Phases
Birth Control
36 Actively Recruiting
Phase 4, Not Applicable, Phase 3, Phase 2, Early Phase 1
Metastatic Breast Cancer
80 Actively Recruiting
Phase 2, Not Applicable, Phase 3, Phase 1, Phase 4
Osteoporosis
44 Actively Recruiting
Phase 1, Phase 2, Not Applicable, Phase 4, Phase 3
Hormone Replacement Therapy
0 Actively Recruiting
Postmenopausal Osteoporosis
4 Actively Recruiting
Not Applicable, Phase 4, Phase 3
Hot flashes
19 Actively Recruiting
Phase 2, Not Applicable, Phase 1, Phase 4, Early Phase 1
Low Testosterone
18 Actively Recruiting
Phase 1, Phase 2, Phase 4
Hormonal Contraception
0 Actively Recruiting
Hypogonadism
0 Actively Recruiting
Vasomotor Symptoms Associated With Menopause
9 Actively Recruiting
Phase 3, Phase 2, Not Applicable
Hysterectomy
1 Actively Recruiting
Phase 4
Postmenopause
7 Actively Recruiting
Phase 2, Not Applicable, Phase 3
moderate to severe symptoms
0 Actively Recruiting
Atrophic
5 Actively Recruiting
Phase 4, Phase 2, Not Applicable, Early Phase 1
no menstrual period in previous 6 months
0 Actively Recruiting
Urogenital atrophy
0 Actively Recruiting
Kraurosis Vulvae
0 Actively Recruiting
Breast Cancer
720 Actively Recruiting
Phase 1, Phase 2, Phase 3, Not Applicable, Early Phase 1, Phase 4
Premature Menopause
0 Actively Recruiting
Breast
0 Actively Recruiting
Bijuva Reviews: What are patients saying about Bijuva?
5Patient Review
9/11/2020 I've been taking Bijuva for just under a year now and it's really helped.
5Patient Review
9/30/2020 I'm really pleased with this medication.
5Patient Review
6/20/2021 I've tried two different treatments and had bad reactions to both of them. I was willing to put up with it because they were working so well, but my doctor suggested Bijuvia and it's been a week with no negative side effects so far.
5Patient Review
7/20/2020 I just started taking Bijuva and it's fantastic.
5Patient Review
1/11/2021 This treatment is really effective. I was amazed at how well it worked and how quickly I felt better.
4.7Patient Review
8/4/2020 Bijuva helped me get rid of my hot flashes and sleep better. I also saw an improvement in my sex life. However, after taking it for about 5 months, I've gained 15 pounds.
4.3Patient Review
2/14/2022 The night sweats have disappeared, sleeping well but I have gained 8lbs in two months. I need to find a solution without gaining weight.
3Patient Review
9/30/2021 I'm experiencing a lot of unpleasant side effects from this medication, including leg cramps, kidney and back pain, acne, and emotional outbursts. It's like going through PMS all over again. I hope the hot flashes stop soon.
2.3Patient Review
8/18/2020 I experienced a 14 pound weight gain by the second packet. I have always been lucky and not had trouble with controlling my weight. Also, fatigue was an issue too. It did however stop the night sweats but unfortunately was not a good fit for me.
2.3Patient Review
8/5/2020 When I first started taking bijuva, I felt great. My mood was better and I didn't have any vaginal dryness.
2Patient Review
11/9/2022 I strongly advise against this medication if you have a history of depression. It exacerbated my condition to the point where I was suicidal. Once I stopped taking it, however, I felt better within days. Additionally, it also caused me pain in my gallbladder.
2Patient Review
9/14/2022 I had high hopes for this medication, but unfortunately it has not helped me sleep better at all. In fact, I feel bloated and have gained several pounds since starting to take it a month ago.
Patient Q&A Section about bijuva
Is Bijuva a bioidentical hormone?
"Bijuva contains estradiol and progesterone that are chemically identical to the hormones that women produce naturally." - Anonymous Online Contributor
Unverified Answer
Does Bijuva make you gain weight?
"Since Bijuva contains the hormones estradiol (a form of estrogen) and progesterone, it's possible that you may experience weight gain as a side effect of Bijuva. If you're concerned about weight gain or weight loss while taking Bijuva, talk with your doctor to see if this is a normal side effect or something to be concerned about." - Anonymous Online Contributor
Unverified Answer
What are the benefits of taking Bijuva?
"1 capsule of BIJUVA once a day can help with moderate to severe hot flashes by replacing the estrogen your body loses during menopause. A study showed that BIJUVA can reduce the frequency and severity of moderate to severe hot flashes in menopausal women." - Anonymous Online Contributor
Unverified Answer