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What is Accolate
ZafirlukastThe Generic name of this drug
Treatment SummaryZafirlukast is a pill used to treat asthma. It works by blocking a certain type of molecule, called a leukotriene, which can cause your airways to become constricted, inflamed, and produce extra mucus. Zafirlukast is usually taken twice a day and is often used with an inhaled steroid and/or long-acting bronchodilator. Another similar medication is montelukast (Singulair), which is usually taken once daily.
Accolateis the brand name
Accolate Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Accolate
Zafirlukast
1996
32
Approved as Treatment by the FDA
Zafirlukast, commonly known as Accolate, is approved by the FDA for 1 uses like Asthma .Asthma
Helps manage Asthma
Effectiveness
How Accolate Affects PatientsZafirlukast is a medicine used to prevent and treat asthma. People with asthma are more sensitive to the effects of leukotriene D4 (LTD<sub>4</sub>) than non-asthmatic people. Tests have shown that zafirlukast helps block the effects of LTD<sub>4</sub>, LTC<sub>4</sub>, and LTE<sub>4</sub> on airways and skin, as well as preventing LTD<sub>4</sub> from increasing the permeability of the skin and stopping it from causing eosinophils to enter
How Accolate works in the bodyZafirlukast blocks leukotriene D4 and E4 from attaching to their receptors in the body. These molecules are associated with asthma, causing swelling, tightening of airways, and inflammation. By preventing them from binding, zafirlukast helps to reduce the signs and symptoms of asthma.
When to interrupt dosage
The measure of Accolate is contingent upon the diagnosed state. The amount of dosage differs, as per the mode of delivery (e.g. Tablet, film coated or Tablet) indicated in the table beneath.Condition
Dosage
Administration
Chronic Urticaria
, 10.0 mg, 20.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, Tablet - Oral
Asthma
, 10.0 mg, 20.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, Tablet - Oral
Warnings
Accolate ContraindicationsCondition
Risk Level
Notes
Cirrhosis
Do Not Combine
Liver Disease
Do Not Combine
Common Accolate Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The metabolism of Abemaciclib can be decreased when combined with Zafirlukast.
Acalabrutinib
Major
The metabolism of Acalabrutinib can be decreased when combined with Zafirlukast.
Albendazole
Major
The metabolism of Albendazole can be decreased when combined with Zafirlukast.
Alectinib
Major
The metabolism of Alectinib can be decreased when combined with Zafirlukast.
Amiodarone
Major
The metabolism of Amiodarone can be decreased when combined with Zafirlukast.
Accolate Toxicity & Overdose RiskPossible side effects of this medication include skin rash and stomach discomfort.
Accolate Novel Uses: Which Conditions Have a Clinical Trial Featuring Accolate?
160 active studies are currently underway to evaluate the potential of Accolate to provide therapeutic benefit in cases of Chronic Urticaria.Condition
Clinical Trials
Trial Phases
Chronic Urticaria
0 Actively Recruiting
Asthma
160 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 4, Early Phase 1, Phase 3
Accolate Reviews: What are patients saying about Accolate?
5Patient Review
10/1/2008 This drug has been a miracle for me. If I could only take one medication, this would be it. I've experienced fewer headaches and ear aches since taking it, and I no longer have to take my inhaler to bed with me at night.
5Patient Review
10/7/2008 Marax was an older drug I used to take that worked well for me, but this newer medication is even better.
5Patient Review
6/29/2010 I have severe muscle spasms around my lungs whenever I miss two doses of this medication, similar to pleurisy. It took me a while to figure out what was causing the pain, but when I did some research and discovered pleurisy, it perfectly described my symptoms. The pain is unbearable, and my doctors have always just shrugged their shoulders.
5Patient Review
1/27/2011 This medication has been a lifesaver for me. I've been taking it since 1993, and it's helped me immensely. I'm so grateful that it's available to people who need it.
5Patient Review
6/26/2017 I've been taking ACCOLATE for 25 years with great success and no side effects. I've tried other medications in the past, but this is by far the most effective with the least amount of negatives.
5Patient Review
9/23/2009 Accolate was the only thing that worked for me. Singular was a total waste of money in comparison because it did nothing to address my breathing problems.
5Patient Review
6/18/2009 This medication has been great! I hardly ever have to use my inhaler now.
4Patient Review
9/21/2009 My daughter's headaches were actually being caused by Accolate. We didn't make the connection until she forgot to take her medication while on vacation and her headaches disappeared after a few days.
3.3Patient Review
2/26/2009 I was recently advised to discontinue this medication after using it for 15 years. I didn't experience any adverse effects while taking it, but since stopping the medicine my headaches, muscle aches and fatigue are slowly starting to improve.
3Patient Review
8/18/2009 I developed an extreme itch after just one month of using this medication. I had to stop taking it as a result.
2.7Patient Review
8/3/2009 It's not the most convenient medication, having to wait a few hours after taking it to eat anything.
2.3Patient Review
4/28/2011 I was hospitalized due to liver problems, even though I don't drink. The staff kept asking me about my drinking habits, which was really frustrating.
Patient Q&A Section about accolate
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is the generic name for Accolate?
"Zafirlukast is used to prevent asthma attacks in adults and children as young as 5 years old.
Zafirlukast is a medication that is used to prevent asthma attacks in adults and children as young as 5 years old."
Answered by AI
What is the drug Accolate used for?
"This medication is used to control and prevent the symptoms of asthma, such as wheezing and shortness of breath. By controlling these symptoms, it allows you to keep up with your normal activities and prevents you from having to miss work or school. In order to be effective, this medication must be used on a regular basis."
Answered by AI
What is the most common side effect of Accolate?
"Side effects that are common may include: feeling nauseous, having diarrhea, stomach pain; a headache; or. having cold symptoms like a stuffy nose, sneezing, or a sore throat."
Answered by AI