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We started Power when my dad was diagnosed with multiple myeloma, and I struggled to help him access the latest immunotherapy. Hopefully Power makes it simpler for you to explore promising new treatments, during what is probably a difficult time.

Bask
Bask GillCEO at Power
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      Why We Started Power

      We started Power when my dad was diagnosed with multiple myeloma, and I struggled to help him access the latest immunotherapy. Hopefully Power makes it simpler for you to explore promising new treatments, during what is probably a difficult time.

      Bask
      Bask GillCEO at Power
      Learn More About Trials
      How Do Clinical Trials Work?Are Clinical Trials Safe?What Can I Expect During a Clinical Trial?

      68 Ocd Trials Near You

      Power is an online platform that helps thousands of Ocd patients discover FDA-reviewed trials every day. Every trial we feature meets safety and ethical standards, giving patients an easy way to discover promising new treatments in the research stage.

      Learn More About Power
      No Placebo
      Highly Paid
      Stay on Current Meds
      Pivotal Trials (Near Approval)
      Breakthrough Medication

      Deep Brain Stimulation for Neurological and Psychiatric Conditions

      Charlestown, Massachusetts
      We propose to study approach/avoidance behavior as measured by the Approach Avoidance task in 20 epilepsy patients undergoing implementation of depth electrodes for seizure monitoring in the Epilepsy Monitoring Unit at MGH. We will also study the effects of VC/VS electrical stimulation on approach-avoidance conflict in 20 adult patients who have undergone DBS implantation for severe MDD and/or OCD. There are 100-200 patients in the world with DBS electrodes in the VC/VS, and our research team cares for more than any other institution. Both participant groups will be assessed with respect to reward-aversion decision conflict using the task. The task will be performed with concurrent EEG recordings in DBS patients, and with continuous recording through our invasive neurophysiology rig in EMU subjects.
      No Placebo Group

      Trial Details

      Trial Status:Recruiting

      Key Eligibility Criteria

      Disqualifiers:Bipolar, Psychotic Disorder, Substance Abuse, Others

      60 Participants Needed

      Psychological Treatment for Intrusive Thoughts

      Boston, Massachusetts
      The investigators are conducting this study to learn more about the cognitive and attentional processes among individuals with three types of repetitive negative thinking (RNT): mental rituals (as seen in obsessive compulsive disorder, OCD), worries (as seen in generalized anxiety disorder, GAD), and ruminations (as seen in major depressive disorder, MDD). Specifically, the investigators are studying whether psychological treatment can help people with RNT who have trouble stopping unwanted thoughts and shifting their attention.
      No Placebo Group

      Trial Details

      Trial Status:Active Not Recruiting
      Age:18 - 60

      Key Eligibility Criteria

      Disqualifiers:Not Listed

      87 Participants Needed

      TMS for Depression

      Boston, Massachusetts
      The goal of this clinical trial is to test a new brain stimulation treatment target for individuals with depression plus at least one additional psychiatric disorder. The main question is to understand the safety profile of a non-invasive form of brain stimulation called accelerated intermittent theta burst stimulation when it is targeting the posterior parietal cortex. Additional questions focus on whether this stimulation improves symptoms of depression and other psychiatric disorders as well as whether this stimulation changes brain function.
      No Placebo Group

      Trial Details

      Trial Status:Active Not Recruiting
      Trial Phase:Early Phase 1
      Age:18 - 65

      Key Eligibility Criteria

      Disqualifiers:Pregnancy, Autism, Neurological Illness, Others
      Must Not Be Taking:Ketamine, Esketamine, ECT, Others

      10 Participants Needed

      Transcranial Magnetic Stimulation for Mental Illness

      Boston, Massachusetts
      Participants will receive Transcranial Magnetic Stimulation (TMS) at a random location in the left prefrontal cortex, excluding sites that are potentially unsafe. Extensive behavioral testing will be conducted to determine which behaviors are modulated by stimulating which circuits.
      No Placebo Group

      Trial Details

      Trial Status:Recruiting
      Trial Phase:Phase 2
      Age:18 - 65

      Key Eligibility Criteria

      Disqualifiers:Pregnancy, Cluster B Disorders, PTSD, Others
      Must Not Be Taking:Ketamine, Esketamine, ECT

      180 Participants Needed

      Cognitive Behavioral Therapy for Depression

      Boston, Massachusetts
      To examine the effectiveness and clinical care outcomes of cognitive-behavioral therapy interventions at Massachusetts General Hospital (MGH).
      No Placebo Group

      Trial Details

      Trial Status:Active Not Recruiting
      Trial Phase:Unphased

      Key Eligibility Criteria

      Disqualifiers:Active Suicidality, Untreated Bipolar, Psychosis, Others

      250 Participants Needed

      Computerized Psycho-social Intervention for Anxiety Disorders

      Tallahassee, Florida
      Anxiety disorders are the most common form of psychopathology, and frequently begin in childhood, resulting in lifelong impairment. Increased brain activity after making mistakes, as reflected by the error-related negativity (ERN), is observed in people with anxiety disorders, even before disorder onset. The ERN is therefore of great interest as a potentially modifiable risk factor for anxiety. However, methodological issues can make the ERN difficult to measure. Increased brain activity in response to a balance disturbance, as reflected by the balance N1, resembles the ERN, but does not share its methodological issues. The investigators' preliminary data demonstrate that the balance N1 and the ERN are associated in amplitude in adults, suggesting they may depend on the same brain processes. The balance N1 has never been investigated in individuals with anxiety disorders, but it increases in amplitude within individuals under anxiety-inducing environmental contexts. Further, balance and anxiety are related in terms of brain anatomy, daily behavior, disorder presentation, and response to treatment. The present investigation will measure the ERN and the balance N1 in children (ages 9-12) with anxiety disorders, and further, how these brain activity measures change in response to a brief, 45-minute, computerized psychosocial intervention that was developed to reduce reactivity to errors, and has been shown to reduce the ERN. The investigators will recruit approximately 80 children with anxiety disorders, half of whom will be randomly assigned to the active intervention condition. The other half will be assigned to an active control condition, consisting of a different 45-minute computerized presentation. Participants assigned to the control condition can access the computerized intervention after participation in the study. The purpose of this investigation is to test the hypothesis that the balance N1 and the ERN will be reduced to a similar extent after the intervention, to demonstrate that these brain responses arise from shared brain processes. Transfer of the effect of the psycho-social intervention to the balance N1 would provide insight into prior work demonstrating that balance training can alleviate anxiety in young children, and well-documented benefits of psychotherapy to balance disorders. Collectively, these data may guide the development of multidisciplinary interventions for the prevention and treatment of anxiety disorders in children.
      No Placebo Group

      Trial Details

      Trial Status:Recruiting
      Trial Phase:Unphased
      Age:9 - 12

      Key Eligibility Criteria

      Disqualifiers:Depression, ADHD, Severe Psychopathology, Others

      80 Participants Needed

      tVNS + ERP for Obsessive-Compulsive Disorder

      Gainesville, Florida
      In the proposed investigation, the investigator will develop pilot data for the use of tVNS (transcutaneous vagal nerve stimulation) to enhance efficacy of exposure and response prevention therapy (ERP) to improve treatment success in patients with OCD. This data will include tolerability information from therapists and patients with OCD, effect sizes on real world clinical outcomes for the combinatory treatment, and mechanistic data on brain changes associated with treatment.

      Trial Details

      Trial Status:Recruiting
      Trial Phase:Unphased
      Age:18 - 55

      Key Eligibility Criteria

      Disqualifiers:Neurological Conditions, Autism, Psychosis, Others

      56 Participants Needed

      Family Cognitive Behavioral Therapy for Obsessive-Compulsive Disorder

      Vancouver, British Columbia
      Obsessive-Compulsive Disorder (OCD) is a common neuropsychiatric illness beginning in childhood. Effective OCD treatments include cognitive-behaviour therapy (CBT) and medications but access to treatment is difficult and does not systematically include parents. The investigators will evaluate clinical and neural effects of Group-based Family CBT (GF-CBT), via a case-control study including: Group 1 - OCD cases receiving GF-CBT (N=90); Group 2 - OCD waitlist cases (N=90). Effects will be measured between baseline and completion of 12 GF-CBT sessions: comparing OCD severity and functioning changes between Groups 1 and 2.
      No Placebo Group

      Trial Details

      Trial Status:Recruiting
      Trial Phase:Unphased
      Age:5 - 18

      Key Eligibility Criteria

      Disqualifiers:Bipolar, Psychosis, Autism, Others

      180 Participants Needed

      Why Other Patients Applied

      "I've been struggling with ADHD and anxiety since I was 9 years old. I'm currently 30. I really don't like how numb the medications make me feel. And especially now, that I've lost my grandma and my aunt 8 days apart, my anxiety has been even worse. So I'm trying to find something new."

      FF
      ADHD PatientAge: 31

      "I have dealt with voice and vocal fold issues related to paralysis for over 12 years. This problem has negatively impacted virtually every facet of my life. I am an otherwise healthy 48 year old married father of 3 living. My youngest daughter is 12 and has never heard my real voice. I am now having breathing issues related to the paralysis as well as trouble swallowing some liquids. In my research I have seen some recent trials focused on helping people like me."

      AG
      Paralysis PatientAge: 50

      "As a healthy volunteer, I like to participate in as many trials as I'm able to. It's a good way to help research and earn money."

      IZ
      Healthy Volunteer PatientAge: 38

      "I was diagnosed with stage 4 pancreatic cancer three months ago, metastatic to my liver, and I have been receiving and responding well to chemotherapy. My blood work revealed that my tumor markers have gone from 2600 in the beginning to 173 as of now, even with the delay in treatment, they are not going up. CT Scans reveal they have been shrinking as well. However, chemo is seriously deteriorating my body. I have 4 more treatments to go in this 12 treatment cycle. I am just interested in learning about my other options, if any are available to me."

      ID
      Pancreatic Cancer PatientAge: 40

      "My orthopedist recommended a half replacement of my right knee. I have had both hips replaced. Currently have arthritis in knee, shoulder, and thumb. I want to avoid surgery, and I'm open-minded about trying a trial before using surgery as a last resort."

      HZ
      Arthritis PatientAge: 78
      Match to a Ocd Trial
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      Why We Started Power

      We started Power when my dad was diagnosed with multiple myeloma, and I struggled to help him access the latest immunotherapy. Hopefully Power makes it simpler for you to explore promising new treatments, during what is probably a difficult time.

      Bask
      Bask GillCEO at Power
      Learn More About Trials
      How Do Clinical Trials Work?Are Clinical Trials Safe?What Can I Expect During a Clinical Trial?
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      Frequently Asked Questions

      How much do Ocd clinical trials pay?

      Each trial will compensate patients a different amount, but $50-100 for each visit is a fairly common range for Phase 2–4 trials (Phase 1 trials often pay substantially more). Further, most trials will cover the costs of a travel to-and-from the clinic.

      How do Ocd clinical trials work?

      After a researcher reviews your profile, they may choose to invite you in to a screening appointment, where they'll determine if you meet 100% of the eligibility requirements. If you do, you'll be sorted into one of the treatment groups, and receive your study drug. For some trials, there is a chance you'll receive a placebo. Across Ocd trials 30% of clinical trials have a placebo. Typically, you'll be required to check-in with the clinic every month or so. The average trial length for Ocd is 12 months.

      How do I participate in a study as a "healthy volunteer"?

      Not all studies recruit healthy volunteers: usually, Phase 1 studies do. Participating as a healthy volunteer means you will go to a research facility several times over a few days or weeks to receive a dose of either the test treatment or a "placebo," which is a harmless substance that helps researchers compare results. You will have routine tests during these visits, and you'll be compensated for your time and travel, with the number of appointments and details varying by study.

      What does the "phase" of a clinical trial mean?

      The phase of a trial reveals what stage the drug is in to get approval for a specific condition. Phase 1 trials are the trials to collect safety data in humans. Phase 2 trials are those where the drug has some data showing safety in humans, but where further human data is needed on drug effectiveness. Phase 3 trials are in the final step before approval. The drug already has data showing both safety and effectiveness. As a general rule, Phase 3 trials are more promising than Phase 2, and Phase 2 trials are more promising than phase 1.

      Do I need to be insured to participate in a Ocd medical study?

      Clinical trials are almost always free to participants, and so do not require insurance. The only exception here are trials focused on cancer, because only a small part of the typical treatment plan is actually experimental. For these cancer trials, participants typically need insurance to cover all the non-experimental components.

      What are the newest Ocd clinical trials?

      Most recently, we added Deep Brain Stimulation for Obsessive-Compulsive Disorder, Freespira Breathing System for Anxiety and Exercise for Obsessive-Compulsive Disorder to the Power online platform.

      What is the best treatment for OCD?

      Think of OCD care in layers. First-line is either Exposure-and-Response-Prevention therapy (a special form of CBT) or an SSRI medicine—using whichever you can access and are willing to try, or both together for the strongest results. If symptoms remain, your clinician can adjust the SSRI dose, add a low-dose antipsychotic, or consider brain-stimulation options such as TMS or (rarely) deep-brain stimulation, so there is usually another step to take.

      What are the 3 C's of OCD?

      The “3 C’s” are a CBT shorthand: Catch the intrusive thought or urge, Check whether the fear is realistic or helpful, and Change it by replacing the thought with a balanced statement while choosing not to perform the compulsion. It’s a handy self-talk tool, but lasting improvement for OCD usually also requires exposure-and-response prevention therapy and, at times, medication, so consult a qualified clinician if symptoms are frequent or distressing.

      Will I ever be normal again after OCD?

      With the right treatment—typically exposure-and-response-prevention therapy, often paired with an SSRI—most people see their OCD symptoms fall by about half, and roughly one in two reach minimal-symptom or full-remission levels, letting them work, study, and socialise much like anyone else. OCD is a vulnerability that can flare under stress, but using the coping skills learned in therapy (and medication if prescribed) keeps those flare-ups brief, so “normal life” is a realistic, long-term expectation for the majority of treated patients. If symptoms do creep back, a short booster course of therapy or medication adjustment usually restores control.

      Is OCD neurodivergent?

      Clinically, OCD is listed in DSM-5 as an “Obsessive-Compulsive and Related Disorder,” not a neurodevelopmental condition like autism or ADHD. Socially, many people still count it as “neurodivergent” because its symptoms stem from lifelong differences in brain circuits and it often overlaps with other neurodivergent diagnoses. In practice, you can use the neurodivergent label if it helps you seek understanding and accommodations, while still pursuing proven treatments such as exposure-and-response-prevention therapy and medication.

      What is the 15 minute rule for OCD?

      The “15-minute rule” is a starter exercise in exposure-and-response-prevention therapy: when an urge to do a ritual appears, you set a timer and deliberately wait 15 minutes without giving in. During that short pause the anxiety usually rises, then naturally ebbs, teaching your brain that the thought is safe and loosening the habit loop; over time you lengthen the delay or skip the ritual altogether. It’s a training tool, not a cure, so use it alongside a therapist’s guidance—especially if urges remain intense or daily life is being disrupted.

      Which OCD has poor prognosis?

      OCD tends to have a poorer long-term outlook when it starts early and remains untreated, when insight is weak or delusional, when hoarding or tic-related symptoms dominate, or when severe depression, substance use, or strong family accommodation are also present. People without these features—especially those who seek treatment soon after onset, have good insight, and lack major comorbidities—generally respond well to standard therapy and medication. In short, it is the combination of early, severe, insight-poor, hoarding/tic-related, and highly comorbid presentations that carries the worst prognosis.

      When is OCD at its peak?

      Most people first develop OCD in one of two windows—late childhood (about ages 8-12) or late adolescence/early adulthood (about 18-25)—but once the disorder is present its severity can rise and fall throughout life. Symptoms often flare again during big hormonal or life stresses such as puberty, pregnancy/post-partum, major losses, or serious illness, so the true “peak” is different for each person and can happen more than once. If obsessive thoughts or rituals start to interfere with daily living at any age, a mental-health professional can offer proven treatments like exposure-response-prevention therapy and medication.

      What exacerbates OCD?

      OCD tends to worsen when your stress system is cranked up (e.g., during major life stress, poor sleep, high caffeine or stimulant use, hormonal changes, illness, or suddenly stopping medication) or when compulsions keep getting “fed” by you or well-meaning family members. Spotting and dialing down these triggers—steady sleep, limiting stimulants, managing stress, sticking to prescribed meds, and practicing exposure-and-response-prevention rather than giving in—can help prevent or calm flare-ups. If symptoms suddenly spike or disrupt daily life, contact a mental-health professional promptly.

      Why was OCD removed from anxiety?

      In DSM-5 (2013), OCD was taken out of the anxiety-disorders chapter and placed in a new group called “Obsessive-Compulsive and Related Disorders” because research showed it behaves differently from classic anxiety illnesses: it centers on intrusive obsessions and ritualistic compulsions, involves partly distinct brain circuits and genes, responds best to higher-dose SSRIs and exposure-response prevention therapy, and clusters with conditions like body-dysmorphic disorder and hoarding. Anxiety is still very common in OCD, but these biological, clinical, and treatment differences made experts create a separate category so diagnosis and care could be more accurate.

      What is the success rate of deep brain stimulation for OCD?

      Across all studies, about half of people with severe, treatment-resistant OCD improve substantially after deep-brain stimulation—“substantial” usually means at least a 35 % drop in symptom scores, and reported success ranges from roughly 40 % to 70 % depending on the exact brain target used. Side-effects such as surgical infection, device problems, or brief mood changes occur in a small minority, so DBS is considered a reasonable last-resort option when medications and therapy have failed, ideally delivered in experienced centers that can fine-tune the settings and monitor patients long-term.