This trial is evaluating whether PTeye will improve 2 primary outcomes and 12 secondary outcomes in patients with Hypoparathyroidism. Measurement will happen over the course of Collected immediately following surgery.
This trial requires 160 total participants across 2 different treatment groups
This trial involves 2 different treatments. PTeye is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.
"The main goal of treatment is not necessarily cure but, rather, long-term cure or remission. Surgical resection may reduce symptoms in 1/4 of patients and even long-term cure (about 20% in our cohort) in 30-40% of cases in the most experienced centres." - Anonymous Online Contributor
"Hyper and hypocalcemia can have a serious effect on patients and it is the major reason of the admission to the Internal Medicine Service in the Internal Medicine Department of Universidad Autónoma de Santander." - Anonymous Online Contributor
"Physicians and scientists should seriously consider trial for high-risk PTH-related bone demineralization disease for those with high PTH levels, or high risk PTH-related skeletal loss for those who have high Ca x P product." - Anonymous Online Contributor
"Parathyroid diseases are most commonly caused by an increase in serum calcium, due to hyperparathyroidism or vitamin D deficiency. If parathyroid hyperplasia or adenomas are present, disease must be detected before surgery. When adenomas are detected, surgery often has good long-term results." - Anonymous Online Contributor
"There is a vast number of parathyroid-related disease with all types of abnormal hormone-producing parathyroid tissue and is a leading reason for the cause for low calcium levels and hypoparathyroidism. An exhaustive, detailed history with regards to physical, laboratory, radiological investigations and all other problems/interventions as well as the use of medication will aid in diagnosis and treatment." - Anonymous Online Contributor
"Based on this review, there were many new treatments, such as radioactive iodine, scanning, PET imaging, and magnetic resonance imaging (MRI) in this discipline, but also the use of certain conventional treatments." - Anonymous Online Contributor
"Symptoms may appear in the early phase of the disease. The primary complaint includes headache, and other systemic manifestations may depend on the sites of involvement." - Anonymous Online Contributor
"Approximately 3% to 4% of people are diagnosed with primary hyperparathyroidism, approximately 1% to 1.5% with secondary hyperparathyroidism, and approximately 13% of people develop persistent or chronic osteitis fibrosa. While there were no significant differences in parathyroid disease prevalence between men and women, women had significantly more severe disease." - Anonymous Online Contributor
"Due to the high prevalence, parathyroid biopsy remains a diagnostic tool of choice for patients with chronic kidney disease. The increased use of parathyroid biopsy in older patients with kidney disease suggest that our knowledge and understanding of the pathological process, such as micro-involvement, has gained more confidence. The number of patients with parathyroid carcinoma and hypoparathyroidism is increasing." - Anonymous Online Contributor
"This is the first study reporting the prevalence of pteye. Results from a recent paper indicate a higher prevalence in women than men. The common side effects reported include nausea, vomiting, diarrhea, itching, chest pain, and tachycardia but were not specific to women." - Anonymous Online Contributor
"The percentage of patients who received PT alone was 7.3% but doubled to 14.8% when PT was used in combination with the other drugs. A combination of PT and ATC was most common in the elderly." - Anonymous Online Contributor
"The drug is well tolerated with an insignificant increase in haemorrhage in this small pilot study. However, it is important that larger studies are conducted to ascertain if PTE is an effective alternative to a placebo in the treatment of primary hyperparathyroidism." - Anonymous Online Contributor