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Visual Rehabilitation Training for Stroke

N/A
Recruiting
Research Sponsored by University of Rochester
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Willing and safely able to undergo magnetic resonance imaging (MRI) scanning
Reliable visual field defects in both eyes as measured by Humphrey, Macular Integrity Assessment (MAIA), Goldmann, and/or equivalent perimetry. This deficit must be large enough to enclose a 5-deg diameter visual stimulus.
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, 6 months, 12 months
Awards & highlights

Study Summary

This trial will help researchers understand how the visual system changes after a stroke, and how to better restore vision for people suffering from cortical blindness.

Who is the study for?
This trial is for US and Canada residents who've had a stroke damaging the primary visual cortex within the last 6 months, leading to reliable vision defects. Participants must be able to undergo MRI scans, speak English fluently, have good enough eyesight (20/40 or better), and can do daily visual training at home.Check my eligibility
What is being tested?
The study tests how well different types of visual training help recover sight after a stroke. It involves exercises in both the intact and blind parts of the field of vision, comparing early versus late training effects on brain plasticity and vision restoration.See study design
What are the potential side effects?
Since this trial focuses on non-invasive visual training exercises rather than medication or surgery, side effects are minimal but may include eye strain or fatigue from regular practice.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I can safely have an MRI scan.
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I have significant vision loss in both eyes confirmed by specific eye tests.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, 6 months, 12 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, 6 months, 12 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Direction Discrimination Threshold
Secondary outcome measures
Contrast Sensitivity for Direction
Direction Integration Threshold
Ganglion cell complex thickness laterality
+3 more
Other outcome measures
Goldmann perimetry
Humphrey 10-2 and 24-2 perimetry
MAIA Visual Field Perimetry

Trial Design

2Treatment groups
Experimental Treatment
Group I: Training in the intact fieldExperimental Treatment2 Interventions
Training in the intact field using specialized software
Group II: Training in the blind fieldExperimental Treatment2 Interventions
Training in the blind field using specialized software

Find a Location

Who is running the clinical trial?

University of RochesterLead Sponsor
840 Previous Clinical Trials
534,190 Total Patients Enrolled
2 Trials studying Homonymous Hemianopia
60 Patients Enrolled for Homonymous Hemianopia
National Institutes of Health (NIH)NIH
2,705 Previous Clinical Trials
7,507,318 Total Patients Enrolled

Media Library

Chronic Training in the blind field Clinical Trial Eligibility Overview. Trial Name: NCT04798924 — N/A
Homonymous Hemianopia Research Study Groups: Training in the blind field, Training in the intact field
Homonymous Hemianopia Clinical Trial 2023: Chronic Training in the blind field Highlights & Side Effects. Trial Name: NCT04798924 — N/A
Chronic Training in the blind field 2023 Treatment Timeline for Medical Study. Trial Name: NCT04798924 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How many participants has this research project enrolled thus far?

"Affirmative. Clinicaltrials.gov confirms that this study, which was first listed on July 19th 2021 is actively recruiting 60 participants from a single medical center. The most recent update to the trial's information was made on October 4th 2022."

Answered by AI

To whom is this research project open for participation?

"This clinical study is recruiting 60 individuals aged between 21 and 75 who have experienced a hemorrhagic stroke. Participants must be mentally competent, willing to complete their visual training on their own for multiple months, as well as possess reliable visual field defects that can accommodate a 5-degree diameter stimulus measured by Humphrey's Perimetry, Macular Integrity Assessment (MAIA), Goldmann or equivalent techniques."

Answered by AI

Is this research program currently recruiting participants?

"Affirmative. The clinicaltrials.gov portal states this medical experiment, which was first made available on July 19th 2021, is proactively recruiting enrollees. Approximately 60 participants are needed at 1 trial site."

Answered by AI

Is the eligibility for this medical study restricted to those over 65 years of age?

"The age-range for this trial is 21 to 75. Those who are younger than that must look into one of the 44 different trials available; those over 65 can consider any of the 1065 other studies on offer."

Answered by AI
~16 spots leftby Jun 2025