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PET/MR vs CECT Scans for Ovarian Cancer

N/A

Waitlist Available

Led By Priya R Bhosale

Research Sponsored by M.D. Anderson Cancer Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up up to 3 years

Awards & highlights

Study Summary

This trialcompares PET/MR and CECT scans to see if PET/MR scans can help find ovarian cancer tumors, predict surgery outcomes, and predict patient responses to chemotherapy.

Who is the study for?

This trial is for adults with confirmed or suspected ovarian cancer who can undergo laparoscopic surgery to see if tumors can be removed. They must have a kidney function test (eGFR) over 30. It's not for those allergic to gadolinium, with eGFR under 30, pacemakers, pregnant women, children, weigh over 400 pounds, or high blood sugar.Check my eligibility

What is being tested?

The study compares PET/MR scans against standard CECT scans in detecting and assessing ovarian cancer tumors. It aims to determine if PET/MR provides better information on tumor location, surgical removal success prediction and response to platinum-based chemotherapy.See study design

What are the potential side effects?

Potential side effects may include reactions to contrast agents used in imaging like gadolinium (for MRI) such as nausea or itching. The CT scan may expose patients to radiation which carries a risk of cancer but this is very low.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ up to 3 years

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~up to 3 years

This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 3 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Lesion detection accuracy

Secondary outcome measures

Diagnostic accuracy by location

Imaging and genomic data analysis

Response status

Trial Design

1Treatment groups

Experimental Treatment

Group I: Diagnostic (CECT, PET-MRI)Experimental Treatment3 Interventions

Patients undergo standard of care CECT scan and PET-MRI scan over 90-120 minutes within 30 days before laparoscopy or cytoreduction. Patients who do not undergo cytoreduction based on diagnostic laparoscopy undergo additional PET-MRI and standard of care CECT scans after completion of chemotherapy and before cytoreduction.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Positron Emission Tomography

2008

Completed Phase 2

~2240

Magnetic Resonance Imaging

2017

Completed Phase 3

~1190

Do I qualify?Apply below to find out

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Who is running the clinical trial?

M.D. Anderson Cancer CenterLead Sponsor

2,967 Previous Clinical Trials

1,804,781 Total Patients Enrolled

47 Trials studying Ovarian Cancer

16,745 Patients Enrolled for Ovarian Cancer

National Cancer Institute (NCI)NIH

13,657 Previous Clinical Trials

40,933,646 Total Patients Enrolled

286 Trials studying Ovarian Cancer

73,766 Patients Enrolled for Ovarian Cancer

Priya R BhosalePrincipal InvestigatorM.D. Anderson Cancer Center

3 Previous Clinical Trials

20,073 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How many participants are currently being recruited for this clinical research?

"Affirmative. Clinicaltrials.gov data suggests that this clinical trial is actively recruiting participants, having been posted on May 12th 2018 and updated most recently on October 12th 2022. 60 patients are sought to take part in the study at a single location."

Answered by AI

Is participation in this clinical trial open to the public now?

"Yes, this clinical trial is still actively recruiting patients. It was first listed on the 5th of December 2018 and edited most recently on the 10th of October 2022. The protocol involves 60 volunteers from a single location."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

PET/MR Versus CECT Scans in Imaging Patients With Ovarian Cancer or Highly Suspected Ovarian Cancer

2018. "PET/MR Versus CECT Scans in Imaging Patients With Ovarian Cancer or Highly Suspected Ovarian Cancer". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03965481.