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Positive Memory Therapy for PTSD

Led By Ateka Contractor, PHD
Research Sponsored by University of North Texas, Denton, TX
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
18-65 years old
Past month DSM-5 posttraumatic stress disorder (PTSD) diagnosis
Screening 3 weeks
Treatment 7 weeks
Follow Up 3 months
Awards & highlights


This trial will examine the effects of a novel PTSD technique that focuses on narrating and detailing positive memories on PTSD symptom severity and stress systems' dysregulation. It aims to provide evidence for the potential significance of targeting positive memories in PTSD interventions.

Who is the study for?
This trial is for adults aged 18-65 with a recent PTSD diagnosis who speak English and can consent to participate. It's not suitable for those currently pregnant, in other mental health therapy, with active suicidal thoughts or psychosis, or recent changes in psychiatric meds.Check my eligibility
What is being tested?
The study tests a new technique called PPMT that focuses on positive memories to help with PTSD symptoms against Supportive Counseling (SC). Participants will be randomly assigned to one of these two treatments to see which is more effective at reducing PTSD severity and stress markers.See study design
What are the potential side effects?
Since the interventions involve counseling techniques without medication, significant physical side effects are not expected. However, discussing traumatic experiences may cause emotional discomfort or temporary increases in distress.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
I am between 18 and 65 years old.
I have been diagnosed with PTSD in the past month.
I have been diagnosed with PTSD in the last month.


Screening ~ 3 weeks
Treatment ~ 7 weeks
Follow Up ~3 months
This trial's timeline: 3 weeks for screening, 7 weeks for treatment, and 3 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Post-Traumatic Stress Disorder
Secondary outcome measures
Positive and Negative Affect Schedule
Saliva Samples

Trial Design

2Treatment groups
Active Control
Group I: Processing of Positive Memories Technique (PPMT)Active Control1 Intervention
Participants receive 5 60-minute Processing of Positive Memories Technique (PPMT) sessions for PTSD following the treatment procedures as outlined in PPMT therapy manual.
Group II: Supportive Counseling (SC)Active Control1 Intervention
Participants receive 5 60-minute supportive counseling (SC) sessions. SC includes a discussion of the daily monitoring diary and exploration of current issues and concerns.

Research Highlights

Information in this section is not a recommendation. We encourage patients to speak with their healthcare team when evaluating any treatment decision.
Mechanism Of Action
Side Effect Profile
Prior Approvals
Other Research
Common treatments for PTSD include trauma-focused therapies, pharmacological treatments, and novel techniques like the Processing of Positive Memories Technique (PPMT). Trauma-focused therapies, such as Cognitive Behavioral Therapy (CBT) and Eye Movement Desensitization and Reprocessing (EMDR), work by helping patients process and integrate traumatic memories, reducing their emotional impact. Pharmacological treatments, including SSRIs and prazosin, target neurochemical imbalances to alleviate symptoms like anxiety and sleep disturbances. PPMT, a novel technique, enhances the encoding and retrieval of positive memories, which can counteract the negative cognitive and emotional patterns associated with PTSD. These mechanisms are crucial as they address both the psychological and physiological aspects of PTSD, offering a comprehensive approach to symptom reduction and improved mental health.
Sleep as a window to target traumatic memories.Effects of processing positive memories on posttrauma mental health: A preliminary study in a non-clinical student sample.The Effectiveness of Mindfulness Training in Improving the Quality of Life of the War Victims with Post Traumatic stress disorder (PTSD).

Find a Location

Who is running the clinical trial?

University of North Texas, Denton, TXLead Sponsor
9 Previous Clinical Trials
6,719 Total Patients Enrolled
Ateka Contractor, PHDPrincipal InvestigatorUniversity of North Texas Health Science Center

Media Library

Processing of Positive Memories Technique (PPMT) Clinical Trial Eligibility Overview. Trial Name: NCT05523453 — N/A
Post-Traumatic Stress Disorder Research Study Groups: Processing of Positive Memories Technique (PPMT), Supportive Counseling (SC)
Post-Traumatic Stress Disorder Clinical Trial 2023: Processing of Positive Memories Technique (PPMT) Highlights & Side Effects. Trial Name: NCT05523453 — N/A
~13 spots leftby Dec 2024