50 Participants Needed

Sit-to-Stand Tests for Lung Disease

(STS24 Trial)

LV
LV
Overseen ByLee Verweel
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: West Park Healthcare Centre
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to determine if sit-to-stand (STS) tests can be effectively conducted at home for individuals with chronic lung issues like asthma or COPD (chronic obstructive pulmonary disease). It will compare performing these tests at a healthcare center, at home with remote supervision, and independently, to identify the most effective method. Eligible participants include those diagnosed with a chronic lung condition, capable of completing at least five sit-to-stand repetitions in a minute without using their arms, and possessing the necessary technology for video calls. As an unphased trial, this study provides a unique opportunity to contribute to research that could enhance home-based care for chronic lung conditions.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

What prior data suggests that the sit-to-stand tests are safe for patients with chronic respiratory disease?

Research shows that sit-to-stand (STS) tests are safe for people with lung diseases. In one study, participants experienced no serious problems or injuries during the one-minute STS test, indicating no major issues occurred. The test was easy to manage, with no difficulties in movement or coordination.

The STS test often assesses exercise capacity, especially in individuals with lung conditions like chronic obstructive pulmonary disease (COPD). It has been tried and tested in similar groups. While the test can increase heart rate and cause shortness of breath, these effects are normal and not harmful.

Overall, the STS test is considered safe and effective for evaluating physical performance in people with lung disease.12345

Why are researchers excited about this trial?

Researchers are excited about the Sit-to-Stand (STS) tests for lung disease because they offer a flexible and accessible way to monitor lung function without the need for traditional clinic visits. Unlike standard methods, which often require patients to travel for in-person testing, the STS tests can be self-administered at home or remotely supervised through video calls, providing convenience and potentially increasing patient adherence. Additionally, the ability to conduct these tests independently at home allows for more frequent monitoring, which could lead to better management of lung disease symptoms over time.

What evidence suggests that this trial's sit-to-stand tests could be effective for lung disease?

Research has shown that sit-to-stand (STS) tests effectively measure exercise ability in people with chronic lung diseases. For those with COPD, about 23–33% experience reduced ability to perform daily activities, which STS tests can help assess. Studies have found that the 1-minute STS test closely matches a person's exercise capacity, providing a reliable view of their endurance. In this trial, participants will be assigned to different conditions: some will perform the STS tests independently at home, others with remote supervision, and some at a healthcare center under direct supervision. These tests aim to make exercise assessments more accessible outside traditional clinical settings for those with lung conditions.678910

Who Is on the Research Team?

DB

Dina Brooks, PhD

Principal Investigator

West Park Healthcare Centre

Are You a Good Fit for This Trial?

This trial is for individuals with chronic respiratory disease (CRD) who are interested in participating in a study to evaluate the effectiveness of sit-to-stand (STS) tests when done at home, either supervised remotely or self-administered.

Inclusion Criteria

Access to technology for remote supervision (e.g., mobile phone, laptop/computer, iPad)
I have a pulse oximeter at home to check my heart rate and oxygen levels.
I have been diagnosed with a chronic lung condition.
See 1 more

Exclusion Criteria

I had surgery on my leg in the last 3 months.
I have difficulty standing up from a seated position due to nerve or muscle issues.
Medically unstable to perform exercise tests (e.g., no exacerbation in the preceding two weeks)
See 1 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks

Orientation

Participants attend an initial orientation meeting over videoconference to review the study process and data collection, including instruction on completing the STS tests at home.

30 minutes
1 visit (virtual)

Testing

Participants complete the 30-second and 1-minute STS tests across three conditions (centre-based, remote, self-administered) with random order over a 7-day period.

7 days
3 visits (mixed: in-person and virtual)

Follow-up

Participants complete a questionnaire regarding the feasibility and acceptability of different testing conditions.

1 day

What Are the Treatments Tested in This Trial?

Interventions

  • Sit-to-Stand Test (STS)
Trial Overview The study is testing how well STS tests work when done outside of a medical center. Participants will perform two types of STS tests: one lasting 30 seconds and another lasting one minute, under three conditions: at a center, supervised remotely, or on their own.
How Is the Trial Designed?
3Treatment groups
Experimental Treatment
Active Control
Group I: Self-Administered ConditionExperimental Treatment1 Intervention
Group II: Remotely Supervised ConditionExperimental Treatment1 Intervention
Group III: Centre-Based ConditionActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

West Park Healthcare Centre

Lead Sponsor

Trials
36
Recruited
2,400+

Citations

Home-based or remote exercise testing in chronic ...Main outcome – home and remote use: Exercise tests that have been used at home in people with chronic lung disease were the 6MWT (two studies), five times STS ( ...
A Remotely Supervised Exercise Program for Lung Cancer ...The purpose of this study is to conduct a pilot randomized controlled trial (RCT) evaluating the feasibility and potential effectiveness of a remotely ...
Effect of a home-based pulmonary rehabilitation program ...The aims of this study are to evaluate the efficacy of home-based PR on functional capacity and health-related quality of life in people with ILD.
Remote assessment of exercise capacity in adults with ...In this single centre cohort study MIST supervised remotely via video-conferencing was safe, reliable and acceptable to people with chronic respiratory disease.
Sit-to-Stand Tests for Lung Disease (STS24 Trial)Trial Overview The study is testing how well STS tests work when done outside of a medical center. Participants will perform two types of STS tests: one lasting ...
The utility and safety of one-minute sit-to-stand test in ...No serious adverse events or motor impairments occurred with the 1STST. The minimum SpO2 during the tests was significantly lower with the 6MWT (92.6 ± 3.1 vs.
The minimal important difference of one-minute-sit-to-stand ...The 1-min-STS test has been validated for assessing exercise capacity in COPD, ILD, and other lung disorders. [21] Importantly, the 1-min-STS ...
The Sit-to-Stand Test: A key assessment tool in modern ...The STS test is a critical metric for assessing functional strength and mobility, particularly in sedentary patients.
Cut-off values of one-minute sit-to-stand test for ...The 1STST resulted in higher heart rate, systolic blood pressure, and dyspnea compared to the 6MWT, and showed a significant moderate ...
Impact of Chair Seat Height on the 1-Minute Sit to Stand ...The 1-minute sit to stand (1-min STS) test is a standardized test which is used to examine exercise capacity in patients with chronic obstructive pulmonary ...
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