Hemodialysis for Chronic Kidney Failure
What You Need to Know Before You Apply
What is the purpose of this trial?
The study will determine the efficacy of twice weekly hemodialysis in patients with residual kidney function.
Do I need to stop taking my current medications for the trial?
The trial information does not specify whether you need to stop taking your current medications. However, if you are using antibiotics or expect to use them, you may not be eligible to participate.
Is hemodialysis safe for humans?
How does twice-weekly hemodialysis differ from other treatments for chronic kidney failure?
Twice-weekly hemodialysis is unique because it is an incremental approach that starts with fewer sessions per week, which can help preserve the remaining kidney function in patients who still have some kidney activity. This contrasts with the more common thrice-weekly schedule, which is often used regardless of the patient's residual kidney function.34567
What data supports the effectiveness of the treatment Thrice weekly hemodialysis, Twice weekly hemodialysis for Chronic Kidney Failure?
Research suggests that starting with twice-weekly hemodialysis can help preserve remaining kidney function in patients who still have some kidney activity, which may improve survival and quality of life. This approach is especially considered for patients with significant residual kidney function, as it may slow down the decline of kidney function compared to more frequent dialysis.34678
Who Is on the Research Team?
Tammy Sirich, MD
Principal Investigator
Stanford/VA Palo Alto Health Care System
Are You a Good Fit for This Trial?
This trial is for stable dialysis patients who can consent to participate. It's not for those who've used antibiotics in the last two months, expect to use them soon, were recently hospitalized, or have very low residual kidney function (<2.5 mL/min).Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo two 4-week study periods with twice weekly versus thrice weekly hemodialysis
Follow-up
Participants are monitored for safety and effectiveness after treatment, including quality of life and cognitive assessments
What Are the Treatments Tested in This Trial?
Interventions
- Thrice weekly hemodialysis
- Twice weekly hemodialysis
Find a Clinic Near You
Who Is Running the Clinical Trial?
Palo Alto Veterans Institute for Research
Lead Sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Collaborator