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Chemotherapy + Radiation for Pancreatic Cancer

N/A
Waitlist Available
Research Sponsored by University of South Florida
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Histologically or cytologically confirmed pancreatic adenocarcinoma
Locally or regionally advanced disease
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 5 years
Awards & highlights

Study Summary

This trial is studying chemotherapy, radiation therapy, and brachytherapy to see how well they work in treating patients with pancreatic cancer.

Who is the study for?
This trial is for adults over 18 with advanced pancreatic cancer that can't be surgically removed. They should have no other cancers in the past 5 years, except certain skin, cervical or early-stage prostate cancers. Participants need normal blood counts and organ function, and must not be pregnant or nursing. Those who are fertile must use contraception.Check my eligibility
What is being tested?
The study compares two treatments: both groups receive chemotherapy drugs fluorouracil and gemcitabine with external-beam radiation therapy; one group also gets brachytherapy using radioactive phosphorus P32 to see if it's more effective at killing tumor cells.See study design
What are the potential side effects?
Chemotherapy may cause nausea, fatigue, hair loss, increased risk of infection due to low blood cell counts, and mouth sores. Radiation could lead to skin irritation at the treatment site and fatigue. Brachytherapy might result in localized pain or discomfort.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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My diagnosis is pancreatic cancer, confirmed by a lab test.
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My cancer has spread to nearby tissues or lymph nodes.
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My condition cannot be treated with surgery due to its severity or my health issues.
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I am 18 years old or older.
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I can care for myself but may not be able to do active work.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 5 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 5 years for reporting.

Treatment Details

Find a Location

Who is running the clinical trial?

University of South FloridaLead Sponsor
412 Previous Clinical Trials
187,059 Total Patients Enrolled
Alexander Rosemurgy, MDStudy ChairUniversity of South Florida
2 Previous Clinical Trials
170 Total Patients Enrolled

Media Library

External-Beam Radiation Therapy Clinical Trial Eligibility Overview. Trial Name: NCT00079365 — N/A
Pancreatic Cancer Research Study Groups:
Pancreatic Cancer Clinical Trial 2023: External-Beam Radiation Therapy Highlights & Side Effects. Trial Name: NCT00079365 — N/A
External-Beam Radiation Therapy 2023 Treatment Timeline for Medical Study. Trial Name: NCT00079365 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any spots still available for participation in this experiment?

"The clinicaltrials.gov website lists this trial as not currently recruiting for participants, with the original posting on May 1st 2001 and last edit made in December 3rd 2013. Despite that, there are still 1353 medical studies seeking patients at present."

Answered by AI
Recent research and studies
clinicaltrials.govStudy
Fluorouracil, External-Beam Radiation Therapy, and Gemcitabine With or Without Brachytherapy Using Phosphorus P32 in Treating Patients With Locally or Regionally Advanced Unresectable Adenocarcinoma of the Pancreas
2001. "Fluorouracil, External-Beam Radiation Therapy, and Gemcitabine With or Without Brachytherapy Using Phosphorus P32 in Treating Patients With Locally or Regionally Advanced Unresectable Adenocarcinoma of the Pancreas". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT00079365.
All > Adenocarcinoma > Flu
~15 spots leftby Apr 2025
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