Sleep Intervention for Duchenne Muscular Dystrophy
(DMD Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This project will systematically plan and evaluate the implementation of the Transdiagnostic Sleep and Circadian Intervention for youth (TranS-CY). As an early stage study, investigators will focus on recruitment strategies to reach the target population and collection of preliminary data on primary and secondary effects of the TranS-CY. Weekly remote (video web conferencing) parent training sessions will allow investigators to explore adoption through parent adherence and examine whether the essential elements of the TranS-CY intervention (e.g., motivational interviewing, goal setting, problem solving, sleep routine scheduling, monitoring) can be consistently taught by clinicians and implemented by parents into the home setting.
Do I have to stop my current medications for this trial?
The trial protocol does not specify whether you need to stop taking your current medications. However, if your child is currently receiving an intervention for a sleep-related disorder, they cannot participate in the trial.
What safety data exists for the sleep intervention treatment for Duchenne Muscular Dystrophy?
The provided research does not directly address safety data for the sleep intervention treatment specifically in the context of Duchenne Muscular Dystrophy. However, the Transdiagnostic Sleep and Circadian Intervention (TranS-C) has been studied in adolescents for improving sleep and circadian functioning, with some studies focusing on its effects on sleep and rest-activity rhythms, as well as its potential to improve depression symptoms. These studies suggest that TranS-C is being evaluated for its effectiveness and potential benefits, but specific safety data, especially in the context of Duchenne Muscular Dystrophy, is not detailed in the provided abstracts.12345
Is the treatment Transdiagnostic Behavioral Sleep Intervention promising for improving sleep in people with Duchenne Muscular Dystrophy?
What data supports the idea that Sleep Intervention for Duchenne Muscular Dystrophy is an effective treatment?
The available research shows that the Sleep Intervention, known as TranS-C, has been effective in improving sleep and related issues in adolescents with various conditions. For example, one study found that TranS-C helped improve sleep and daily activity patterns in adolescents who preferred staying up late. Another study showed that it helped reduce symptoms of depression in teens with a tendency to stay up late. While these studies focus on other conditions, they suggest that TranS-C can effectively improve sleep and related health outcomes, which could be beneficial for those with Duchenne Muscular Dystrophy as well.134910
Who Is on the Research Team?
Angela Caldwell, PhD
Principal Investigator
University of Pittsburgh
Are You a Good Fit for This Trial?
This trial is for English-speaking parents or caregivers of boys aged 6-17 with Duchenne Muscular Dystrophy (DMD) who live at home and have access to a smartphone or computer with internet. It's not suitable for those whose children have cognitive/behavioral issues that would limit participation, or are currently receiving sleep disorder treatments.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Pre-phase
Initial interview and ActiGraph data collection to characterize the sample and gather baseline data
Intervention Implementation
Weekly video-conference meetings for parent training and education on sleep health, with data collection on parent attendance and feedback
Post-Intervention
ActiGraph data collection to assess changes in sleep efficiency after the intervention
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Transdiagnostic Behavioral Sleep Intervention
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Pittsburgh
Lead Sponsor