Education for Melanoma Prevention in Hispanics

Age: 18+

Sex: Any

Trial Phase: Phase 2

Sponsor: Mayo Clinic

Disqualifiers: Non-Hispanic, Under 18, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Prior Safety Data This treatment has passed at least one previous human trial

Compensation: Varies

Number of Visits: 2

145 Participants Needed

Trial Summary

What is the purpose of this trial?

This clinical trial is to develop an educational platform to educate and prevent melanoma in Hispanic populations. Melanoma is cancer arising in the skin. Educational platforms to increase the knowledge and practice of sun smart behaviors (sunscreen use, sun protective clothing use, self-skin examination) may help reduce risk of and incidence of melanoma and improve cancer survival.

Will I have to stop taking my current medications?

The trial protocol does not specify whether you need to stop taking your current medications.

What data supports the effectiveness of the treatment Educational Intervention, PRE-ACT Model, Patient Navigator Model for melanoma prevention in Hispanics?

Research shows that educational interventions, like the multimedia 'Skinsafe' and web-based 'mySmartSkin', improve knowledge and protective behaviors against melanoma. Additionally, a review highlights the need for more Spanish-language materials to educate Hispanic patients on sun safety and skin cancer, suggesting that targeted education can be beneficial. ^{1 2 3 4 5}

Is the educational intervention for melanoma prevention safe for humans?

The educational interventions reviewed, such as community-based healthcare worker and video-based programs, have been used to educate Spanish-speaking patients about sun safety and skin cancer without any reported safety concerns. ^{1 3 4 6 7}

How is the Educational Intervention treatment for melanoma prevention in Hispanics different from other treatments?

The Educational Intervention treatment is unique because it focuses on educating Spanish-speaking patients about sun safety and skin cancer through community-based healthcare worker interventions and video-based materials, rather than using traditional medical treatments or drugs. ^{4 8 9 10 11}

Research Team

Aaron Mangold

Principal Investigator

Mayo Clinic

Eligibility Criteria

This trial is for Hispanic or Latino individuals, aged 18 and older, who are patients at the Mayo Clinic with an email on file. It aims to educate them about melanoma prevention. Those not fitting this description cannot participate.

Inclusion Criteria

Patients who identify themselves as Hispanic or Latino and receive care at the Mayo Clinic.

Have an email on file with Mayo Clinic

Exclusion Criteria

All patients who do not meet inclusion criteria

Timeline

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Educational Training

Participants complete an educational training module and a questionnaire at baseline

1 week

1 visit (virtual)

Follow-up

Participants complete a follow-up questionnaire to assess knowledge retention and behavior change

3 months

1 visit (virtual)

Treatment Details

Interventions

• Educational Intervention

Trial Overview The study is testing an educational program designed to increase awareness and encourage behaviors that protect against melanoma, like using sunscreen, wearing sun-protective clothing, and performing self-skin examinations.

Participant Groups

Group I: Prevention (Educational training) Experimental Treatment 2 Interventions

Participants complete an educational training module and complete questionnaire at baseline (before educational training module) and 3 months after completing educational training.

Who Is Running the Clinical Trial?

Mayo Clinic

Lead Sponsor

Trials

3,427

Recruited

3,221,000+

National Cancer Institute (NCI)

Collaborator

Trials

14,080

Recruited

41,180,000+

Findings from Research

The Skinsafe multimedia intervention significantly improved melanoma knowledge among patients, with scores increasing from 3.03 in the control group to 3.71 in the intervention group after 6 months (P < 0.001).

Patients who received the Skinsafe intervention reported more protective skin behaviors and were more likely to check their moles, indicating that the program effectively encouraged proactive skin health practices.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Impact of a multimedia intervention "Skinsafe" on patients' knowledge and protective behaviors. Glazebrook, C., Garrud, P., Avery, A., et al.[2006]

A study involving 150 middle school students in South Los Angeles showed that many students, particularly Latino youth, lacked knowledge about skin cancer risks and sun safety before educational intervention, but after receiving education, 94% expressed intent to use sunscreen in the future.

Post-intervention, 80% of students reported some sunscreen use, with 24% of Latino students using it daily, highlighting the effectiveness of education in improving sun safety practices, although cost remains a barrier for consistent use.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Dermatologic health literacy in underserved communities: a case report of south Los Angeles middle schools. Chapman, LW., Ochoa, A., Tenconi, F., et al.[2022]

Malignant melanoma is increasingly common, with a 7% annual rise in incidence, highlighting the urgent need for effective prevention and detection strategies.

A new public education program targeting schools, pediatricians, nurses, and state agencies aims to educate at-risk populations about melanoma and skin cancer, potentially improving early detection and prevention efforts.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

A plan to promote the prevention and early detection of melanoma. Harris, J.[2016]

References

1. United States pubmed.ncbi.nlm.nih.gov

Impact of a multimedia intervention "Skinsafe" on patients' knowledge and protective behaviors. [2006]

2. United States pubmed.ncbi.nlm.nih.gov

Efficacy of a partner assistance intervention designed to increase skin self-examination performance. [2016]

3. England pubmed.ncbi.nlm.nih.gov

Randomized controlled trial of the mySmartSkin web-based intervention to promote skin self-examination and sun protection among individuals diagnosed with melanoma. [2022]

4. Germany pubmed.ncbi.nlm.nih.gov

Dermatology education resources on sun safety and skin cancer targeted at Spanish-speaking patients: a systematic review. [2023]

5. United States pubmed.ncbi.nlm.nih.gov

Adherence to Adjuvant Therapy in Patients with Resected Melanoma: An Application of the Theory of Planned Behavior. [2023]

6. United States pubmed.ncbi.nlm.nih.gov

Trends in primary skin cancer prevention among US Hispanics: a systematic review. [2021]

7. Netherlands pubmed.ncbi.nlm.nih.gov

Sharing and seeking information about skin cancer risk and prevention among Hispanic people from Florida and Puerto Rico. [2023]

8. United States pubmed.ncbi.nlm.nih.gov

Dermatologic health literacy in underserved communities: a case report of south Los Angeles middle schools. [2022]

9. United States pubmed.ncbi.nlm.nih.gov

A randomized trial to improve early detection and prevention practices among siblings of melanoma patients. [2007]

10. United States pubmed.ncbi.nlm.nih.gov

A plan to promote the prevention and early detection of melanoma. [2016]

11. United States pubmed.ncbi.nlm.nih.gov

Melanoma in US Hispanics: recommended strategies to reduce disparities in outcomes. [2021]