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1 for Liver Failure

N/A
Waitlist Available
Led By Ralph Lattermann, MD PhD
Research Sponsored by McGill University Health Centre/Research Institute of the McGill University Health Centre
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up one day before and one day after surgery
Awards & highlights

Study Summary

The goal of the study is to determine whether intravenous glucose administration before liver resection preserves hepatic glycogen resulting in improved hepatic metabolic function after the operation. We further investigate whether the benefit of avoiding preoperative fasting is more pronounced in patients undergoing more extensive liver resection.

Eligible Conditions
  • Liver Failure

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~one day before and one day after surgery
This trial's timeline: 3 weeks for screening, Varies for treatment, and one day before and one day after surgery for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Rate of albumin synthesis
Secondary outcome measures
Transthyretin synthesis, fibrinogen synthesis, whole body glucose and protein kinetics

Trial Design

2Treatment groups
Active Control
Placebo Group
Group I: 1Active Control1 Intervention
Glucose infusion.
Group II: 2Placebo Group1 Intervention
Normal saline infusion.

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Who is running the clinical trial?

McGill University Health Centre/Research Institute of the McGill University Health CentreLead Sponsor
442 Previous Clinical Trials
159,124 Total Patients Enrolled
2 Trials studying Liver Failure
876 Patients Enrolled for Liver Failure
Ralph Lattermann, MD PhDPrincipal InvestigatorDepartment of Anaesthesia, McGill University Health Centre
1 Previous Clinical Trials
460 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Preoperative Glucose Infusion: a Novel Strategy to Improve Liver Function After Liver Resection
Ralph Lattermann 2008. "Preoperative Glucose Infusion: a Novel Strategy to Improve Liver Function After Liver Resection". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT00623662.
All > Liver Fibrosis
~3 spots leftby Apr 2025
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