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Carbohydrate Fueling

Carbohydrate Mixtures for Energy Deficiency

N/A
Recruiting
Research Sponsored by United States Army Research Institute of Environmental Medicine
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Men and women aged 18 - 39 years
Willing to refrain from alcohol, smoking/using any nicotine product (includes e-cigarettes, vaping, chewing tobacco), caffeine, and dietary supplements while consuming the study diet
Must not have
Musculoskeletal injuries that compromise exercise capability
Unwilling or unable to consume study diets or foods provided due to personal preference, dietary restrictions, and/or food allergies
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 80 minutes
Awards & highlights

Summary

This trial will study the effects of consuming a mixture of glucose and fructose versus glucose alone on the body's use of carbohydrates during exercise and physical performance. Participants will go through various tests and measurements to

Who is the study for?
This trial is for individuals who are willing to participate in a study examining how different carbohydrate combinations affect exercise performance and energy use. Participants should be comfortable with exercise protocols, including cycling, and must undergo various tests such as body composition assessments, blood draws, and muscle biopsies.Check my eligibility
What is being tested?
The study is testing the effects of consuming glucose alone or combined with fructose on carbohydrate burning rates during aerobic exercise under balanced and deficit energy conditions. It involves controlled diet, steady-state cycling exercises followed by a time trial test to measure physical performance.See study design
What are the potential side effects?
Since this trial involves dietary interventions rather than drugs or medical procedures, side effects may include gastrointestinal discomfort from the carbohydrate drinks or temporary soreness from muscle biopsies.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I am between 18 and 39 years old.
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I am willing to avoid alcohol, nicotine, caffeine, and supplements for the study.
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My menstrual cycles are regular, between 26-32 days, or I am on continuous birth control.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
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I have injuries that limit my ability to exercise.
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I cannot follow the study's diet due to my dietary preferences, restrictions, or allergies.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~80 minutes
This trial's timeline: 3 weeks for screening, Varies for treatment, and 80 minutes for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Exogenous carbohydrate oxidation
Secondary outcome measures
Time to exhaustion

Trial Design

4Treatment groups
Experimental Treatment
Active Control
Group I: Energy Deficit: Glucose plus FructoseExperimental Treatment1 Intervention
Following 48 hours of consuming an energy deficit diet, volunteers complete 80 min of steady-state (60 ± 5% V̇O2peak) exercise on a cycle ergometer while consuming 53 g of glucose and 27 g of fructose.
Group II: Energy Balance: Glucose plus FructoseExperimental Treatment1 Intervention
Following 48 hours of consuming an energy balance diet, volunteers complete 80 min of steady-state (60 ± 5% V̇O2peak) exercise on a cycle ergometer while consuming 53 g of glucose and 27 g of fructose.
Group III: Energy Balance: GlucoseActive Control1 Intervention
Following 48 hours of consuming an energy balance diet, volunteers complete 80 min of steady-state (60 ± 5% V̇O2peak) exercise on a cycle ergometer while consuming 80 g of glucose
Group IV: Energy Deficit: GlucoseActive Control1 Intervention
Following 48 hours of consuming an energy deficit diet, volunteers complete 80 min of steady-state (60 ± 5% V̇O2peak) exercise on a cycle ergometer while consuming 80 g of glucose

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Who is running the clinical trial?

United States Army Research Institute of Environmental MedicineLead Sponsor
62 Previous Clinical Trials
3,582 Total Patients Enrolled
~5 spots leftby Dec 2024