Allulose for Calorie Burning

Overseen By Nick Bellissimo

Age: 18 - 65

Sex: Any

Trial Phase: Academic

Sponsor: Toronto Metropolitan University

Disqualifiers: Diabetes, Pregnancy, Gastrointestinal, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 3

Duration: 3 days

10 Participants Needed

Trial Summary

What is the purpose of this trial?

The objective of this study is to investigate the dose-response effect of allulose on diet-induced thermogenesis, substrate oxidation, glycemic response, and subjective appetite in healthy normal weight adults.

Research Team

Nick Bellissimo

Principal Investigator

Toronto Metropolitan University

Eligibility Criteria

Healthy adults aged 18-45, non-smokers with a normal weight BMI (20-24.9 kg/m2), can join this trial. Those with diabetes, gastrointestinal, liver or kidney disease, on conflicting diets or medications affecting metabolism and intake regulation, pregnant or possibly pregnant women, allergic to test ingredients, unable to complete tests, having high fasting glucose levels or recent major medical events are excluded.

Inclusion Criteria

I am 18-45 years old, healthy, don't smoke, and have a normal BMI.

Exclusion Criteria

Participants with previously diagnosed diabetes

I have a gastrointestinal condition.

Participants who were or are on a diet that may confound the study

Timeline

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks

Treatment

Participants consume varying doses of allulose on 3 separate days with energy expenditure and glucose monitoring

3 days

3 visits (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment

1 week

Treatment Details

Interventions

• Allulose

Trial Overview The study is testing how different doses of allulose affect the body's heat production after eating (diet-induced thermogenesis), fat and sugar burning rates (substrate oxidation), blood sugar levels (glycemic response), and feelings of hunger in healthy individuals.

Participant Groups

Group I: Allulose Dose 3 Experimental Treatment 1 Intervention

Treatment

Group II: Allulose Dose 2 Experimental Treatment 1 Intervention

Treatment

Group III: Allulose Dose 1 Experimental Treatment 1 Intervention

Treatment

Who Is Running the Clinical Trial?

Toronto Metropolitan University

Lead Sponsor

Trials

95

Recruited

19,300+

Anderson Advanced Ingredients

Industry Sponsor

Trials

2

Recruited

30+