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Exercise for Alzheimer's Disease

N/A
Recruiting
Led By J. Carson Smith, PhD
Research Sponsored by University of Maryland, College Park
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
60 to 80 years old
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline and 6 months
Awards & highlights

Study Summary

This trial is comparing the effects of six months of moderate exercise to six months of flexibility training on brain function, cognition, and physical function in adults aged 60-80.

Who is the study for?
This trial is for physically inactive adults aged 60-80, who are cognitively healthy and fluent in English. They must be willing to commit time to the study and have a doctor's approval for moderate exercise. People with neurological conditions, untreated major health issues, severe depression, substance abuse, or certain medication use cannot participate.Check my eligibility
What is being tested?
The study compares a 6-month program of moderate intensity aerobic exercise (ET) versus low-intensity flexibility exercises (FC) on brain function and memory in older adults at risk for Alzheimer's. Participants will be randomly assigned to one of these two groups and activities take place in retirement communities or university campus.See study design
What are the potential side effects?
Since this trial involves physical activity, potential side effects may include muscle soreness, fatigue, joint pain or injury. However, risks are minimized by medical oversight and tailored exercise plans.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am between 60 and 80 years old.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline and 6 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline and 6 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change from Baseline to 6 months in Resting Cerebral Blood Flow
Change from Baseline to 6 months in Rey Auditory Verbal Learning Test Sum of Trials 1-5
Secondary outcome measures
Change from Baseline to 6 months in 6 Minute Walk Test
Change from Baseline to 6 months in VO2peak

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Exercise TrainingExperimental Treatment1 Intervention
Group exercise and treadmill walking
Group II: Flexibility ControlActive Control1 Intervention
Group exercise and flexibility exercise

Find a Location

Who is running the clinical trial?

University of Maryland, College ParkLead Sponsor
155 Previous Clinical Trials
45,513 Total Patients Enrolled
National Institute on Aging (NIA)NIH
1,672 Previous Clinical Trials
28,018,511 Total Patients Enrolled
Johns Hopkins UniversityOTHER
2,262 Previous Clinical Trials
14,823,012 Total Patients Enrolled

Media Library

Exercise Training Clinical Trial Eligibility Overview. Trial Name: NCT03727360 — N/A
Healthy Cognition Research Study Groups: Exercise Training, Flexibility Control
Healthy Cognition Clinical Trial 2023: Exercise Training Highlights & Side Effects. Trial Name: NCT03727360 — N/A
Exercise Training 2023 Treatment Timeline for Medical Study. Trial Name: NCT03727360 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are recruitment efforts currently underway for this trial?

"Affirmative. Clinicaltrials.gov data confirms that enrollment for this clinical trial is ongoing; it was first posted on October 8th 2018 and most recently updated on November 14th 2022. The study is looking to recruit 152 participants from one site."

Answered by AI

What is the maximum participant capacity for this research endeavor?

"Affirmative. According to clinicaltrials.gov, this examination is currently recruiting participants who meet the criteria. It was launched on October 8th 2018 and has recently been updated November 14th 2022. 152 people are required for the trial which will take place at one site."

Answered by AI

Does this clinical trial offer access to adults over the age of 35?

"This study has set the age range for participants from 60 to 80 years old. There are 23 clinical trials available specifically targeting those under 18, and 539 studies open to those above 65."

Answered by AI

Do I meet the qualifications necessary to participate in this experiment?

"Prospective participants of this clinical trial must be between 60 and 80 years old, as well as have a diagnosis of Alzheimer's disease. In total, 152 people are required for the study to reach completion."

Answered by AI

Who else is applying?

What state do they live in?
Maryland
What site did they apply to?
University of Maryland, Department of Kinesiology
What portion of applicants met pre-screening criteria?
Met criteria
How many prior treatments have patients received?
0

Why did patients apply to this trial?

Looking for ways to be accountable to someone for exercising. If it possibly helps my long term cognition, so much the better.
PatientReceived 2+ prior treatments
Recent research and studies
clinicaltrials.govStudy
Exercise for Brain Health in the Fight Against Alzheimer's Disease
2018. "Exercise for Brain Health in the Fight Against Alzheimer's Disease". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03727360.
All > Alzheimers Disease Baltimore
~23 spots leftby Apr 2025
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