Blueberry Intervention for Brain Aging

Overseen By Caitlin Boeckman

Age: 65+

Sex: Any

Trial Phase: Academic

Sponsor: University of Kansas Medical Center

Must not be taking: Psychoactive, Investigational

Disqualifiers: Neurological diseases, Psychiatric disorders, Diabetes, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Approved in 1 Jurisdiction This treatment is already approved in other countries

Compensation: Varies

Number of Visits: Unknown

63 Participants Needed

Trial Summary

What is the purpose of this trial?

The purpose of this study is to determine if increased blueberry intake helps increase brain antioxidant (glutathione) and cerebral blood flow in older adults.

Research Team

In-Young Choi, PhD

Principal Investigator

Department of Neurology

Eligibility Criteria

This study is for older adults who are cognitively normal, have a BMI between 18.5-35, speak and read English well, are in good health without serious diseases, and eat very few berries. It's not for pregnant individuals or those with blueberry allergies, major head trauma history, life-threatening illnesses, recent severe psychiatric disorders including depression or anxiety, diabetes, metabolic syndrome or uncontrolled high blood pressure.

Inclusion Criteria

I speak and read English as my primary language.

I am in good health with no other major illnesses.

Low berry consumption (≤1 serving/week)

Exclusion Criteria

I am not taking any psychoactive or investigational drugs.

Presence of major psychiatric disorders within the past 3 years including depression, anxiety, and alcohol or drug abuse

Pregnancy

Treatment Details

Interventions

• Control
• Intervention

Trial Overview The trial is testing whether eating more blueberries can boost brain antioxidants (specifically glutathione) and improve blood flow to the brain in older adults. Participants will be divided into two groups: one that receives an increased amount of blueberries (intervention) and another that does not receive this increase (control).

Participant Groups

Group I: Intervention Experimental Treatment 1 Intervention

Participants will receive the dietary intervention. Participants will take 1 serving of blueberries/day.

Group II: Control Active Control 1 Intervention

Participants will receive a placebo. Participants will take 1 serving of placebo/day.

Intervention is already approved in United States for the following indications:

Approved in United States as Digital Meditation Intervention for:

• Loneliness in Older Adults
• Social Isolation
• Emotional Well-being

Who Is Running the Clinical Trial?

University of Kansas Medical Center

Lead Sponsor

Trials

527

Recruited

181,000+

U.S. Highbush Blueberry Council

Collaborator

Trials

18

Recruited

1,100+