Curcumin C3 complex® +Lovaza® for Lung Disease

H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL
Lung Disease+1 More ConditionsLovaza® - Drug
All Sexes

Study Summary

This trial will test if Lovaza + Curcumin C3 Complex can help reduce the size of lung nodules and if it is safe to take.

Eligible Conditions
  • Lung Disease
  • Lung Cancer Prevention

Treatment Effectiveness

Phase-Based Effectiveness

1 of 3
Phase 2

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Study Objectives

2 Primary · 2 Secondary · Reporting Duration: 6 months post treatment

6 months post treatment
Mean Change in Bronchial Nodule Size
Rate of Adherence
Rate of Nodules ≥4 mm
Month 7
Rate of Treatment Related Adverse Events (AEs)

Trial Safety

Phase-Based Safety

2 of 3
This is further along than 68% of similar trials

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Awards & Highlights

All Individual Drugs Already Approved
Therapies where all constituent drugs have already been approved are likely to have better-understood side effect profiles.
Approved for 5 Other Conditions
This treatment demonstrated efficacy for 5 other conditions.

Trial Design

3 Treatment Groups

Curcumin C3 complex® +Lovaza® +Placebo
1 of 3
Curcumin C3 complex® +Lovaza®
1 of 3
Placebo only
1 of 3

Active Control

75 Total Participants · 3 Treatment Groups

Primary Treatment: Curcumin C3 complex® +Lovaza® · Has Placebo Group · Phase 2

Curcumin C3 complex® +Lovaza® +PlaceboActiveComparator Group · 3 Interventions: Lovaza®, Placebo, Curcumin C3 complex® · Intervention Types: Drug, Other, Drug
Curcumin C3 complex® +Lovaza®ActiveComparator Group · 2 Interventions: Lovaza®, Curcumin C3 complex® · Intervention Types: Drug, Drug
Placebo only
ActiveComparator Group · 1 Intervention: Placebo · Intervention Types: Other

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 6 months post treatment

Who is running the clinical trial?

James and Esther King Biomedical Research ProgramOTHER
13 Previous Clinical Trials
1,759 Total Patients Enrolled
H. Lee Moffitt Cancer Center and Research InstituteLead Sponsor
514 Previous Clinical Trials
128,201 Total Patients Enrolled
Nagi Kumar, Ph.DPrincipal InvestigatorH. Lee Moffitt Cancer Center and Research Institute
1 Previous Clinical Trials

Eligibility Criteria

Age 18+ · All Participants · 4 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You are not allergic to the ingredients in the study medication.
You have a history of smoking at least 20 packs of cigarettes.
If you smoke, you must agree to receive help to quit smoking during the trial.
You can swallow the pills given for the study.

Frequently Asked Questions

Is this a pioneering research endeavor?

"As far back as 2005, Abbott sponsored a trial testing Curcumin C3 complex® +Lovaza®, which eventually led to the drug being approved for Phase 4. Presently, there are 22 active studies of this medication taking place in 19 cities across 8 countries." - Anonymous Online Contributor

Unverified Answer

Has there been any prior research that has incorporated Curcumin C3 complex® +Lovaza®?

"At the present moment, 22 investigations into Curcumin C3 complex® +Lovaza® are in progress. 5 of these experiments have progressed to Phase 3. Moreover, 30 medical sites nationwide are looking at this intervention with many being based in Kansas City, Kansas." - Anonymous Online Contributor

Unverified Answer

Has the FDA sanctioned the combination of Curcumin C3 Complex® and Lovaza®?

"Our team at Power assessed the safety of Curcumin C3 Complex® +Lovaza® to be a 2, as this trial is currently in Phase 2; indicating that there are some data points demonstrating its security yet none proving effectiveness." - Anonymous Online Contributor

Unverified Answer

How many participants are enrolled in this research initiative?

"Affirmative. According to the details posted on, this investigation is actively seeking participants; it was initially uploaded on June 5th 2019 and recently revised on September 30th 2022. As of now, they require 75 individuals from one medical facility." - Anonymous Online Contributor

Unverified Answer

Are there currently any opportunities for participants to join this experiment?

"That is accurate. As per the information on, this medical trial which was first posted in June 2019 is presently recruiting participants. 75 individuals are needed from a single clinic for the study." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.