← Back to Search

Bupivacaine injection for Postoperative Pain (SPGB Trial)

Phase 4

Waitlist Available

Led By Dr. Kesava Reddy, MD

Research Sponsored by Hamilton Health Sciences Corporation

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up through study completion, approximately 1 year

Awards & highlights

SPGB Trial Summary

This trial aims to determine if adding a nerve block during pituitary surgery can help manage pain better after the surgery. Patients will receive either Bupivacaine or a placebo during surgery and will

Who is the study for?

This trial is for individuals undergoing minimally invasive pituitary surgery who need postoperative pain management. Participants must meet certain health criteria to be eligible, but specific inclusion and exclusion details are not provided.Check my eligibility

What is being tested?

The study tests the effectiveness of a nerve block with Bupivacaine-Epinephrine solution versus a placebo (saline) in managing post-surgery pain. Patients' pain levels will be monitored over the first day after surgery to see if this approach reduces their pain medication needs.See study design

What are the potential side effects?

Possible side effects may include reactions at the injection site, such as discomfort or swelling, and systemic effects like dizziness or heart rate changes due to Bupivacaine-Epinephrine. Placebo injections typically have no active side effects.

SPGB Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ through study completion, approximately 1 year

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~through study completion, approximately 1 year

This trial's timeline: 3 weeks for screening, Varies for treatment, and through study completion, approximately 1 year for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Post-operative pain score

Secondary outcome measures

Analgesic requirement

Length of stay

Post-operative bleeding

+1 more

SPGB Trial Design

2Treatment groups

Experimental Treatment

Placebo Group

Group I: Bupivacaine injectionExperimental Treatment1 Intervention

This group will receive bilateral injection of 0.5% bupivacaine with 1:200,000 epinephrine using a 20G needle and comprising 2mL of fluid on each side (4mL total) into the sphenopalatine ganglion.

Group II: Placebo ControlPlacebo Group1 Intervention

This group will receive bilateral injection of 0.9% saline solution using a 20G needle and comprising 2mL of fluid on each side (4mL total) into the sphenopalatine ganglion.

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Hamilton Health Sciences CorporationLead Sponsor

368 Previous Clinical Trials

300,949 Total Patients Enrolled

1 Trials studying Postoperative Pain

103 Patients Enrolled for Postoperative Pain

Dr. Kesava Reddy, MDPrincipal InvestigatorHamilton Health Sciences Corporatin

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is it feasible for me to participate in this clinical trial?

"Candidates with postoperative pain aged 18-100 are eligible for this study, which has space for a total of 52 participants."

Answered by AI

Is the enrollment of participants currently ongoing for this research study?

"According to clinicaltrials.gov, the current status of this medical trial indicates that it is not actively seeking participants. This particular study was initially published on May 1st, 2024 and last revised on April 2nd, 2024. Despite its inactive recruitment status, there are currently 524 other research projects actively looking for eligible candidates."

Answered by AI

Is there an age limit for participation in this research study, specifically concerning individuals older than 30 years?

"To be considered for participation in this research, individuals must meet the age requirements of being at least 18 years old but no older than 100."

Answered by AI