CLINICAL TRIAL

Propofol for Cancer

Recruiting · 18+ · All Sexes · Rochester, NY

This study is evaluating whether a type of anesthesia may help reduce the risk of death following surgery.

See full description

About the trial for Cancer

Eligible Conditions
Surgical Oncology · Neoplasms · Anesthesia, General

Treatment Groups

This trial involves 2 different treatments. Propofol is the primary treatment being studied. Participants will be divided into 2 treatment groups. There is no placebo group. The treatments being tested are in Phase 4 and have been shown to be safe and effective in humans.

Experimental Group 1
Volatile Agent
DRUG
Experimental Group 2
Propofol
DRUG

About The Treatment

Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Propofol
FDA approved

Eligibility

This trial is for patients born any sex aged 18 and older. There are 8 eligibility criteria to participate in this trial as listed below.

Inclusion & Exclusion Checklist
Mark “yes” if the following statements are true for you:
The surgical removal of the gallbladder is called a cholecystectomy show original
Radical (total) cystectomy
Pancreatectomy
is a novel treatment for peritoneal cancer that involves the delivery of high-temperature chemotherapy directly to the site of the tumor show original
Gastrectomy (subtotal or total)
Lobectomy or pneumonectomy
Esophagectomy
Partial hepatectomy
View All
Odds of Eligibility
Unknown<50%
Be sure to apply to 2-3 other trials, as you have a low likelihood of qualifying for this one.Apply To This Trial

Approximate Timelines

Please note that timelines for treatment and screening will vary by patient
Screening: ~3 weeks
Treatment: varies
Reporting: 2 years
Screening: ~3 weeks
Treatment: Varies
Reporting: 2 years
This trial has approximate timelines as follows: 3 weeks for initial screening, variable treatment timelines, and reporting: 2 years.
View detailed reporting requirements
Trial Expert
Connect with the researchersHop on a 15 minute call & ask questions about:
- What options you have available- The pros & cons of this trial
- Whether you're likely to qualify- What the enrollment process looks like

Measurement Requirements

This trial is evaluating whether Propofol will improve 1 primary outcome and 2 secondary outcomes in patients with Cancer. Measurement will happen over the course of Minimum 2 years.

Recurrence free survival
MINIMUM 2 YEARS
Time to event
MINIMUM 2 YEARS
All-cause mortality
2 YEAR MINIMUM
Time to event
2 YEAR MINIMUM
All-cause mortality as a binary outcome
2 YEARS
2 YEARS

Who is running the study

Principal Investigator
E. B.
Prof. Elliott Bennett-Guerrero, Professor and Vice Chairman
Stony Brook University

Patient Q & A Section

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is cancer?

Cancer can be defined as a disease that develops when normal cells grow and divide uncontrollably or excessively, resulting in the formation of new abnormal tissues. Most cancer develops from cells that live in or on the surface of tissues. In many cancers, cells accumulate inside tissues, forming masses that can block or impede vital structures like the lungs, brain, liver, or blood vessels. The cancer in the brain is known as glioblastoma multiforme. Tumours that form in structures deep underneath the skin can cause problems, but the most common form of cancer is lung cancer. Cancer can sometimes be diagnosed by observing blood tests or through medical imaging. There are many different types of cancer and some that come back without treatment will eventually heal.

Anonymous Patient Answer

What are common treatments for cancer?

More than 60% use medical imaging like PET/MRI or CT on an as-needed basis without a formal examination by a professional. Imaging is used at a high frequency in oncology, and this is likely related to the high rates of disease recurrence and high rates of metastasis.

Anonymous Patient Answer

What are the signs of cancer?

Nausea and vomiting (often without warning), loss of appetite and loss of color and bruising may be the first and only signs of cancer. Abdominal pain, swollen neck nodes or a lump are also signs of cancer and may be combined with persistent or worsening coughing. Coughing up blood and blood in urine are other signs of cancer. It is important for all men and women to seek medical help if any of these symptoms persist.

Anonymous Patient Answer

Can cancer be cured?

The ability of cancer cells to revert to a stem cell or a normal cell phenotype is a central process that allows the cell to circumvent the body's natural processes of self-destruction. This process depends on a complex network of molecules and signals called a cancer stem cell (CSC). CSCs can be thought of as a biological self-contained living entity that is self-sufficient and independent. Because of the low frequency of CSCs in tumors (detailed below), it has long been argued that CSCs can not really exist except in the context of a massive and enduring cancer eradication program in most cancers, including those diagnosed in stage 1 and a small number of stage 2 cancers.

Anonymous Patient Answer

What causes cancer?

In general, the causes of cancer and its incidence are multifactorial. However, certain human carcinomas and in specific cases the initiation of carcinogenesis may take place due to a single genetic or environmental agent. The relationship of causation between environment and cancer is still being determined.

Anonymous Patient Answer

How many people get cancer a year in the United States?

Approximately 5.9 million American adults will experience [lung cancer](https://www.withpower.com/clinical-trials/lung-cancer), colon cancer, and/or [breast cancer](https://www.withpower.com/clinical-trials/breast-cancer). About 1.5 million people in the United States will experience prostate cancer. Also, 531,000 people in the United States will have an ovarian cancer diagnosis. About 2.75 million of US adults will be diagnosed with a brain tumor. The next highest incidence of cancer in the nation is in the stomach, colon, lung, urinary bladder, liver, pancreas, breast, hematologic or bone/torus/mammal cells.

Anonymous Patient Answer

Is propofol typically used in combination with any other treatments?

Propofol is typically used in combination with radiation, chemotherapy, chemo-radiotherapy, and/or pain medicine. There appears to be a need to determine a method and means for determining the safest and most effective way to use propofol while using chemotherapy or chemoradiation.

Anonymous Patient Answer

Has propofol proven to be more effective than a placebo?

Propofol appears safe and may be as effective as a placebo in the treatment of pain in a cancer patient experiencing pain or to relieve pain during radiotherapy and/or anesthesia.

Anonymous Patient Answer

What is the primary cause of cancer?

It was cancer that was affecting my ability to perform at my regular work and also with my regular hobbies. I was on the road so much I was going through exhaustion, headaches, a bit of an energy crash so, I needed something to keep me on the wheel. I was putting excessive weight on my body too...and I was consuming a lot of drugs, and that‘s what made me feel sick in my stomach. That was when the colon cancer came. Then that’s when I began to think about this diet. Then I had all this weight on my body, so I had the need to lose some.

Anonymous Patient Answer

Have there been any new discoveries for treating cancer?

There have been a number of research findings since 2000 with no significant impact for the treatment of cancer, but we can assume that cancer is now firmly on the research agenda.

Anonymous Patient Answer

How serious can cancer be?

If an individual with cancer can't do their job, this is a serious problem. Cancer is so harmful, in such devastating ways, that people should have their doctor take care of it, whether they had cancer or not. It's so serious, so important, and so expensive that paying for it in your job is so important. Also, many of our friends and neighbors can't pay for their doctor.

Anonymous Patient Answer
See if you qualify for this trial
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