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Combination Therapy for Type 2 Diabetes
Study Summary
This trial is testing a combination of drugs to see if they can effectively and durably control blood sugar levels in people with type 2 diabetes, which would prevent many of the complications associated with the disease.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- People with type 1 diabetesYou haven't taken any medication for the condition, or you have been taking metformin for less than 3 months.People who have tested positive for GAD antibodies.You have not taken any medication for your condition, or you have been taking metformin for less than 3 months.You have been diagnosed with type 2 diabetes within the last 2 years.You have had diabetes for more than 2 years.You have been taking metformin for more than 3 months, or you have already been taking other medications before joining the study.You are older than 18 years old.You were diagnosed with type 2 diabetes less than 2 years ago.
- Group 1: conventional therapy
- Group 2: Triple Therapy
- Drug Has Already Been Approved - The FDA has already approved this drug, and is just seeking more data.
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Pivotal Trial - The final step before approval, pivotal trials feature drugs that have already shown basic safety & efficacy.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Is participation in this research restricted to individuals over a certain age?
"The requirements to take part in this medical experiment necessitate that the participants are between 18 and 80 years old. Additionally, there are 221 clinical trials tailored towards those under 18 years of age and 1119 studies dedicated to individuals over 65."
Are there still vacancies in this clinical research endeavor?
"Unfortunately, this clinical trial is not accepting new enrollees at the present moment. The study was first posted in 2009 and had its last update on March 8th 2022. On the other hand, if you are looking for additional trials to join, 1266 studies recruiting people with diabetes mellitus are currently operational and 215 of them have openings pertaining to metformin-pioglitazone-exenatide combinations."
What are the requirements for participants to be eligible in this medical research study?
"This trial is seeking 521 diabetics between 18 and 80 years old. Applicants must have been recently diagnosed within the past 2 years, not taken any diabetes medication for at least 3 months or be drug naive, and exceed 18 years of age to qualify."
Are there any prior studies that have explored the usage of metformin, pioglitazone, or exenatide?
"Presently, 215 clinical studies are underway regarding metformin\pioglitazone\exenatide. 53 of these experiments have advanced to Phase 3 with the majority occurring in Chicago, Illinois. Across 2271 medical sites worldwide this medication is being tested."
Have any of the medications metformin, pioglitazone, or exenatide been given clearance by regulators?
"Considering that this is a Phase 4 trial and the treatment has already been approved, our team at Power rated its safety as 3 on a scale of 1 to 3."
What is the aggregate enrolment for this research project?
"Currently, the trial is not accruing participants. It was established on January 1st 2009 and updated most recently on March 8th 2022. If you are seeking alternative studies, there are a total of 1266 trials currently enrolling patients with diabetes mellitus and 215 that involve metformin/pioglitazone/exenatide as treatments."
In what circumstances are metformin\pioglitazone\exenatide typically prescribed?
"To ameliorate diabetes, exercise-related issues, and type 1 diabetes mellitus respectively, metformin, pioglitazone, and exenatide can be deployed."
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