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Aspirin for Pre-eclampsia (ASPERIN Trial)
ASPERIN Trial Summary
This trial will help determine if Aspirin has a dose-dependent response in reducing adverse outcomes related to preeclampsia.
- Pre-eclampsia
ASPERIN Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.ASPERIN Trial Design
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Who is running the clinical trial?
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- Requirements for being included in the control group of the study.You have an autoimmune disease.You have had a type of high blood pressure called "preterm preeclampsia" during a previous pregnancy.You have long-term high blood pressure.You have kidney problems.You do not have any conditions that increase your risk of developing preeclampsia.You have pre-eclampsia and meet the requirements to be part of the study.You have either Type 1 or Type 2 diabetes.
- Group 1: Acetylsalicylic Acid 81mg
- Group 2: Acetylsalicylic Acid 162mg
- Group 3: Control Group
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- All Individual Drugs Already Approved - Therapies where all constituent drugs have already been approved are likely to have better-understood side effect profiles.
- Approved for 10 Other Conditions - This treatment demonstrated efficacy for 10 other conditions.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Are recruitment efforts for this experiment still underway?
"Yes, this information is available on clinicaltrials.gov. The listing says that the trial is actively recruiting and provides the dates 4/25/2019 (original posting) and 7/19/2021 (most recent update)."
What is the FDA's most recent decision on Acetylsalicylic Acid 162 mg?
"Power has given Acetylsalicylic Acid a safety score of 2. This is because, while there is some data supporting its safety, there is currently no evidence that it is an effective medication."
Will this experiment be incorporating elderly participants?
"The target recruitment pool for this study are individuals who have not yet reached middle age (i.e. those younger than 45 years old)."
What are the ideal characteristics for participants in this research?
"250 individuals who have been diagnosed with pre-eclampsia and are aged 18 to 45 can participate in this study. The most crucial requirement for participants is that they cannot have any additional risk factors for preeclampsia, renal diseases, or autoimmune disease."
What is the most frequent purpose of taking Acetylsalicylic Acid 162 mg?
"Acetylsalicylic Acid 162 mg is an effective medical treatment for percutaneous coronary intervention (pci), dental procedures, and inflammation."
How many people are the most that can be a part of this clinical trial?
"Yes, the trial is still ongoing and looking for patients. The information available on clinicaltrials.gov shows that the trial was posted on April 25th, 2019 and updated July 19th, 2021. They are aiming to enroll 250 patients from a single site."
To your knowledge, does a similar study exist?
"Acetylsalicylic Acid 162 mg has been under medical scrutiny since 2002 when it received its first clinical trial. After being sponsored by Sanofi, the drug completed Phase 3 and received approval in 2002. As of now, there are 181 active studies involving Acetylsalicylic Acid 162 mg taking place across 1451 cities and 61 countries."
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