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DHA Supplementation for Alzheimer's Disease (PreventE4 Trial)
PreventE4 Trial Summary
This trial will help us understand if people with a certain gene are more likely to get Alzheimer's and if taking a certain supplement could help prevent it.
PreventE4 Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowPreventE4 Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.PreventE4 Trial Design
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Who is running the clinical trial?
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- I am between 55 and 80 years old.The doctor has determined that you have dementia.You consume more than 200 mg of DHA per day, according to a reliable questionnaire.I am currently being treated for a serious condition like another cancer or HIV.I am taking blood thinners like Plavix, Coumadin, or newer ones.You have at least one risk factor for dementia such as being overweight, having high blood pressure, or high cholesterol.You must score at least 25 on the Mini-Mental State Examination (MMSE) test.You need to be able to remember certain information after a short delay, scoring between 6 and 18 on a memory test.I am currently taking medication for memory problems.You have a history of drinking too much alcohol or using drugs.I have not taken omega-3 supplements in the last 3 months.
- Group 1: Placebo
- Group 2: DHA
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
What is the government agency's opinion of DHA?
"DHA scored a 2 in terms of safety. This is due to the fact that, while there have been Phase 2 trials conducted which support its safety, there are no studies which suggest it is an effective treatment."
If I take part in this research, what are the benefits?
"The aim of this research is to enroll 368 patients that are currently experiencing alzheimer disease. These individuals must be between the ages of 55 and 80. To qualify, potential patients must also meet at least one of the following dementia risk factors: obesity, years spent in education, hypertension, or hyperlipidemia. Additionally, their MMSE score must be greater than 25 and their Logical Memory II delayed recall score must be between 6 and 18."
If I am not yet 55 years old, can I still enroll in this research program?
"Eligibility for this study requires that potential patients are between 55 and 80 years old."
Are people still able to sign up for this research project?
"This particular clinical trial is not presently looking for candidates, as per the information found on clinicaltrials.gov. The study was initially posted on 7/1/2018 and was last updated on 11/10/2022. There are 561 other trials recruiting patients at this time."
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