This trial is evaluating whether IMSA101 will improve 1 primary outcome and 2 secondary outcomes in patients with Cancer. Measurement will happen over the course of 2 years.
This trial requires 115 total participants across 5 different treatment groups
This trial involves 5 different treatments. IMSA101 is the primary treatment being studied. Participants will be divided into 5 treatment groups. There is no placebo group. The treatments being tested are in Phase 1 & 2 and have already been tested with other people.
"The development of cancer depends on the genetic mutation that causes them. This mutation, which may be a change in gene expression, can be caused by environmental factors such as pollution or radiation. Cancer tends to develop gradually from benign to malignant cancer. Other cancers such as thyroid cancer may develop either naturally or from environmental factors such as radiation. In order to prevent cancer, individuals must take control of modifiable risk factors. Dietary factors and cigarette smoking contribute to many of the cancers that cause most deaths." - Anonymous Online Contributor
"Treatment of brain tumors is difficult because of issues such as BBB. But, because a large part of brain tumour has not been found yet, researchers and clinicians have no means to cure cancer. The only cure is to diagnose it correctly and to treat it adequately at the earliest stage." - Anonymous Online Contributor
"Some forms of treatment can be provided using different treatment techniques and the patient's individual characteristics. However, a wide range of procedures are available for cancer treatment even though these vary in their effect and duration." - Anonymous Online Contributor
"Almost 20% of all cancer deaths are of people who were under the age of 50 years when deaths from cancer usually occur, and more than 95% of cancers occur outside health-system surveillance in these individuals. Cancer deaths and incidence rates are lower in older individuals than younger individuals. Cancer incidence also increases with age in most regions in the United States." - Anonymous Online Contributor
"Signs of cancer are mostly nonspecific. They include signs of disease, signs of treatment effects, and signs of complications. It is important that physicians are aware of such signs so as to ensure early diagnosis and prompt treatment." - Anonymous Online Contributor
"Cancer is a disease that can be traced to mutated cells in the body, which then grow or spread. Most cancers start in the body’s normal tissue, either in the skin, colon, breast, or brain. When cancers do form in a child it is usually harmless, such as skin cancer or brain tumors. However, cancer may occasionally grow and spread in children. Cancer is a disease that is relatively treatable if diagnosed early enough. It is estimated that 1 in 3 people will develop cancer in their lifetime. Understanding the signs and symptoms of cancer can help prevent it." - Anonymous Online Contributor
"Imsa101 is safe with a low level of side effects across a wide range of indications. As our preliminary results show that this agent is safe and well tolerated in all ages, its use cannot be excluded in older patients at high risk of chemotherapy related toxicity." - Anonymous Online Contributor
"There has been some speculation that the combination of imsa101 with radiotherapy might be more effective than radiotherapy alone, but further investigation is required before a clear answer to this question can be resolved. A clinical trial to test this hypothesis would have a number of advantages over other current treatments, but would have a small sample size and would require long follow-up, making its results less reliable. The evidence obtained so far would be less persuasive if we do not take into consideration the small but noteworthy number (almost 100,000) of patients and their treatment who have already been treated for cancer." - Anonymous Online Contributor
"IMSA101 showed potent antiviral and antineoplastic effects in preclinical assays of cancer cell lines and a xenograft tumour-growth model. The novel observations are in accordance with observations by the FDA. Given that IMSA101 is in the pre-clinical stage and in advanced stages in human clinical trials, this reinforces its rationale as a therapeutic drug against cancer." - Anonymous Online Contributor
"The effects of Imsa101 were significantly lower than that for a group that was given a placebo. The reason behind these findings remains unclear; however, it would be possible that some patients with the same condition are benefiting significantly more from Ima101 than others. More studies are in progress to ascertain the overall effect. The effects of Ima101 were greater than that for the placebo group, which was expected, as it was based on the results of previous studies. We believe Ima101 to be an effective treatment for the treatment of prostate cancer. But there is no evidence showing that Ima101 increases survival. More research is needed to confirm this effect." - Anonymous Online Contributor
"More research needs to be done before a treatment can be declared effective. The only one in the past couple of decades that has made a difference to patients with cancer is targeted therapy which is specifically focused on the cancer cells. Although they have been in use for at least ten years now, we are still waiting for an approved drug to be the breakthrough treatment for those with cancer that was used to treat metastatic breast cancer over the last decade." - Anonymous Online Contributor
"IMSA101 is a novel compound prepared from the bark of Imsa ajmonu, and appears to share many of the in vivo antitumor effects of the plant." - Anonymous Online Contributor