← Back to Search

Beta Blocker

Blood Pressure Medication for Early Pregnancy Hypertension

Phase 2

Recruiting

Research Sponsored by Marshall University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be between 18 and 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up through study completion, an average of 1 year

Awards & highlights

Study Summary

This trial looks at whether treating high blood pressure in early pregnancy helps outcomes or not.

Who is the study for?

This trial is for pregnant individuals between 12 and 16 weeks gestation, under care at Marshall University offices, with slightly elevated blood pressure (systolic 120-139 or diastolic 80-89). It's not for those already on hypertension medication, with chronic hypertension, substance use disorders, alcohol consumption during pregnancy, diabetes or end stage renal disease.Check my eligibility

What is being tested?

The study compares the effects of treating early pregnancy high blood pressure with either Labetalol or Nifedipine versus no treatment. Participants will be randomly assigned to one of these three groups after giving their consent.See study design

What are the potential side effects?

Labetalol may cause fatigue, headache, dizziness or nausea. Nifedipine can lead to swelling in the legs and feet, flushing, heart palpitations and may occasionally lower your blood pressure too much.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ through study completion, an average of 1 year

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~through study completion, an average of 1 year

This trial's timeline: 3 weeks for screening, Varies for treatment, and through study completion, an average of 1 year for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Treatment of elevated blood pressures

Secondary outcome measures

ICG directed treatment

Trial Design

2Treatment groups

Active Control

Group I: Treatment GroupActive Control2 Interventions

Treatment of elevated blood pressures (120 or greater systolic OR 80 or greater diastolic)

Group II: Non-treatment GroupActive Control1 Intervention

Non-treatment of blood pressures between 120-139 systolic and 80-89 diastolic

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Marshall UniversityLead Sponsor

20 Previous Clinical Trials

3,928 Total Patients Enrolled

Media Library

Labetalol (Beta Blocker) Clinical Trial Eligibility Overview. Trial Name: NCT05955040 — Phase 2

High Blood Pressure Research Study Groups: Treatment Group, Non-treatment Group

High Blood Pressure Clinical Trial 2023: Labetalol Highlights & Side Effects. Trial Name: NCT05955040 — Phase 2

Labetalol (Beta Blocker) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05955040 — Phase 2

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is it possible to join this trial at present?

"In order to be enrolled in this clinical trial, potential participants should have elevated blood pressure and fall within the youthful interval between 18-45 years of age. A total of 234 persons are required for successful completion."

Answered by AI

Does this experiment allow for participants aged 50 or more?

"This particular trial only considers applicants who are 18-45 years old. For people younger than eighteen, there are 50 available studies while those over 65 have a selection of 671 clinical trials to choose from."

Answered by AI

Has Treatment Group received clearance from the Federal Drug Administration?

"While no clinical data exists yet to back up Treatment Group's efficacy, there is evidence that it poses some safety risks which warrants a score of 2."

Answered by AI

Is enrollment still available for this experiment?

"As per the clinicaltrials.gov database, this medical trial has commenced participant recruitment. The details of which were first published on July 11th 2023 and have been amended since then."

Answered by AI

To what extent is public participation in this clinical experiment widespread?

"Affirmative. Per the data posted on clinicaltrials.gov, this research is actively enrolling participants since its inception on July 11th 2023 and last update was also made at that time. The study requires the recruitment of 234 individuals across a single site."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Treatment of Elevated Blood Pressures in Early Pregnancy

Jesse Cottrell 2023. "Treatment of Elevated Blood Pressures in Early Pregnancy". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05955040.