Mobile Health Programs for Smoking Cessation
(ESCAPE Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests two mobile apps designed to help Black individuals with HIV quit smoking. It compares the new ESCAPE app with the existing quitSTART app, both in conjunction with nicotine replacement therapy (NRT). Participants will join one of three groups: ESCAPE + NRT, quitSTART + NRT, or a control group with NRT. Individuals who identify as Black, have HIV, smoke at least five cigarettes daily, and are motivated to quit may be suitable for this trial. As a Phase 2 trial, the research focuses on measuring the treatment's effectiveness in an initial, smaller group.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. However, you must be willing to use nicotine replacement therapy (NRT) as part of the study.
Is there any evidence suggesting that this trial's treatments are likely to be safe?
Research shows that both the ESCAPE app and the quitSTART app are user-friendly. Although detailed safety information for the ESCAPE app is lacking, smoking cessation apps, in general, have successfully helped people quit smoking, suggesting they are safe to use.
For the quitSTART app, studies indicate it is effective and well-received by users trying to quit smoking. One study found that 25% of users successfully quit smoking, demonstrating its effectiveness without any major safety issues reported.
Both apps aim to help people quit smoking and generally have no known serious side effects. It is common and generally safe to use these apps alongside nicotine replacement therapy (NRT). While specific data on side effects is limited, previous studies suggest that using these apps with NRT is safe for participants.12345Why are researchers excited about this trial's treatments?
Researchers are excited about the ESCAPE and quitSTART apps for smoking cessation because they leverage mobile health technology to offer personalized support, which is different from traditional methods like nicotine replacement therapy (NRT) alone. These apps provide interactive features and tailored guidance, making quitting smoking more engaging and accessible. By combining these apps with NRT, there's potential for a more comprehensive approach, addressing both behavioral and physical aspects of nicotine addiction in a way that many current options do not.
What evidence suggests that this trial's treatments could be effective for smoking cessation in Black persons with HIV/AIDS?
Research has shown that mobile health (mHealth) apps can help people quit smoking. In this trial, participants will join different treatment arms. The ESCAPE app, one of the interventions tested, combines smoking cessation treatments with other health supports. This holistic approach has shown promise in aiding smoking cessation.
Another treatment arm involves the quitSTART app. Research has found that personalized digital programs like quitSTART can increase quit rates by 77% compared to standard methods. The app works even better with nicotine replacement therapy (NRT), significantly boosting the chances of quitting smoking. Both apps, when used with NRT, provide helpful tools that can improve the success of quitting smoking.13678Who Is on the Research Team?
Michael S. Businelle, Ph.D.
Principal Investigator
University of Oklahoma Health Sciences
Are You a Good Fit for This Trial?
This trial is for Black individuals living with HIV who smoke at least 5 cigarettes daily for a year, are motivated to quit, and willing to use a mobile app and nicotine replacement therapy (NRT). They must be adults fluent in English without cognitive impairments or recent heart attacks. Pregnant individuals or those planning pregnancy soon cannot participate.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Baseline
Participants complete a baseline appointment to assess initial conditions
Treatment
Participants engage in the intervention or control condition with ecological momentary assessments and weekly follow-ups
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Control (CTRL)
- ESCAPE app
- quitSTART app
Trial Overview
The study tests the effectiveness of two smoking cessation methods among Black persons with HIV: the ESCAPE app plus NRT versus the quitSTART app plus NRT. A control group receives only assessments along with NRT. Participants will be randomly assigned to one of these three groups.
How Is the Trial Designed?
3
Treatment groups
Experimental Treatment
Active Control
Placebo Group
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Houston
Lead Sponsor
University of Oklahoma
Collaborator
Citations
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Protocol for a randomized controlled trial of the Enhanced ...
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Protocol for a randomized controlled trial of the Enhanced ...
This study will test a smoking cessation intervention using personal stories and a lung cancer screening decision-aide compared to standard care.
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