9 Participants Needed

Whey Protein Supplement for Kidney Failure

Recruiting at 1 trial location
JM
Overseen ByJeanette M Andrade, PhD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: University of Florida
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)
Approved in 4 JurisdictionsThis treatment is already approved in other countries

Trial Summary

What is the purpose of this trial?

This is a 6-month prospective interventional clinical trial designed to evaluate the impact of whey protein isolate oral supplement on protein status. Differences in protein status will be evaluated with review of the medical chart from standard of care monthly blood collection for serum albumin, total protein, and normalized protein catabolic rate (nPCR) as detected by serum urea nitrogen. Mid-arm circumference and weight will be measured to ensure no significant changes. Quality of life will be measured to detect if the addition of protein aided in overall quality of life. There will be a 3-month recruitment period prior to the start of the trial to ensure the potential participants are familiarized with the clinical trial. After the recruitment period has finished, eligible participants will sign the consent form in order to participate in the study. At this point, participants will be provided the supplements for the month and instructed with the amount of water and how to mix with the provided measuring and drinking cup.

Research Team

JM

Jeanette M Andrade, PhD

Principal Investigator

University of Florida

Eligibility Criteria

Adults over 18 with stage 5 chronic kidney disease (CKD) who have been on peritoneal dialysis for at least three months. Participants must be able to sign consent, have no dietary restrictions, food allergies, or issues with chewing/swallowing. Pregnant or lactating individuals and those using other protein supplements are excluded.

Inclusion Criteria

I have been diagnosed with stage 5 kidney disease for at least 3 months.
Can provide signed informed consent
I have no issues with chewing or swallowing.
See 3 more

Exclusion Criteria

Use of other protein supplement
Pregnant/lactating as either self-reported or determined by the medical director
My kidney disease is between stages 1 to 4.
See 1 more

Timeline

Screening

Participants are screened for eligibility to participate in the trial

3 months

Treatment

Participants receive 20g total protein of whey protein isolate in 115 mls of water daily

6 months
Monthly visits for blood collection and measurements

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

Treatment Details

Interventions

  • Whey protein supplement
Trial Overview The trial is testing if a whey protein isolate supplement can improve the protein status in adults undergoing peritoneal dialysis. Over six months, participants' blood will be checked monthly for certain proteins and their body measurements taken to see any changes in nutrition and quality of life.
Participant Groups
1Treatment groups
Experimental Treatment
Group I: Whey protein consumptionExperimental Treatment1 Intervention
Participants will receive 20g total protein of whey protein isolate in 115 mls of water to consume daily for up to 6 months

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Florida

Lead Sponsor

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