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Angiotensin II Receptor Agonist

Local lactated Ringer's (control) perfusion for Gender Differences

Q: Are there currently available spots for this clinical investigation?

Affirmative, the information on clinicaltrials.gov plainly demonstrates that this medical trial is actively enrolling patients. It was initially posted on October 3rd 2022 and has been refreshed recently on October 13th of the same year. The study requires 24 individuals to join from 1 particular location.

Q: What is the utmost capacity of individuals participating in this experiment?

Yes, the research project is actively recruiting according to clinicaltrials.gov records. The investigation was first posted on October 3rd 2022 and has since been updated as recently as October 13th 2022. Across one single site, 24 participants are needed for this study.

Q: Does the age of fifty constitute a barrier to participation in this medical experiment?

This medical experiment is looking for volunteers that are between 18 and 35 years of age.

Q: Who meets the criteria for enrollment in this medical research?

This clinical investigation is looking to recruit a cohort of 24 individuals with gender disparities aged 18-35. Eligible participants should be young women or men, have body mass index between 18 and 30 kg/m2, systolic blood pressure less than 140 mmHg and diastolic blood pressure below 90mmHg.

Phase < 1

Waitlist Available

Research Sponsored by Anna Stanhewicz, PhD

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be between 18 and 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up post 1 hour of local control treatment

Awards & highlights

Study Summary

This trial looks at how Angiotensin II receptors and estrogen affect blood pressure, showing pre-menopausal women have a greater protection against cardiovascular diseases.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ post 1 hour of local control treatment

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~post 1 hour of local control treatment

This trial's timeline: 3 weeks for screening, Varies for treatment, and post 1 hour of local control treatment for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Microvascular AT2R sensitivity following local AT1R inhibition

Microvascular AT2R sensitivity following local control treatment

Secondary outcome measures

circulating hormones

Trial Design

2Treatment groups

Experimental Treatment

Group I: Local losartan perfusionExperimental Treatment1 Intervention

~1 hour of losartan is perfused through an intradermal microdialysis fiber

Group II: Local lactated Ringer's (control) perfusionExperimental Treatment1 Intervention

~1 hour of lactated Ringer's is perfused through an intradermal microdialysis fiber

Do I qualify?Apply below to find out

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Who is running the clinical trial?

Anna Stanhewicz, PhDLead Sponsor

9 Previous Clinical Trials

356 Total Patients Enrolled

Media Library

Compound 21 (Angiotensin II Receptor Agonist) Clinical Trial Eligibility Overview. Trial Name: NCT05576155 — Phase < 1

Gender Differences Research Study Groups: Local lactated Ringer's (control) perfusion, Local losartan perfusion

Gender Differences Clinical Trial 2023: Compound 21 Highlights & Side Effects. Trial Name: NCT05576155 — Phase < 1

Compound 21 (Angiotensin II Receptor Agonist) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05576155 — Phase < 1

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there currently available spots for this clinical investigation?

"Affirmative, the information on clinicaltrials.gov plainly demonstrates that this medical trial is actively enrolling patients. It was initially posted on October 3rd 2022 and has been refreshed recently on October 13th of the same year. The study requires 24 individuals to join from 1 particular location."

Answered by AI

What is the utmost capacity of individuals participating in this experiment?

"Yes, the research project is actively recruiting according to clinicaltrials.gov records. The investigation was first posted on October 3rd 2022 and has since been updated as recently as October 13th 2022. Across one single site, 24 participants are needed for this study."

Answered by AI

Does the age of fifty constitute a barrier to participation in this medical experiment?

"This medical experiment is looking for volunteers that are between 18 and 35 years of age."

Answered by AI

Who meets the criteria for enrollment in this medical research?

"This clinical investigation is looking to recruit a cohort of 24 individuals with gender disparities aged 18-35. Eligible participants should be young women or men, have body mass index between 18 and 30 kg/m2, systolic blood pressure less than 140 mmHg and diastolic blood pressure below 90mmHg."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Sex Differences in the Dilatory Response of Compound 21

Anna Stanhewicz, PhD 2022. "Sex Differences in the Dilatory Response of Compound 21". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05576155.