Zithromax
Urethritis, Chancroid, Tonsillitis + 34 more
Treatment
32 FDA approvals
20 Active Studies for Zithromax
Treatment for
Urethritis
What is Zithromax
Azithromycin
The Generic name of this drug
Treatment Summary
Azithromycin is an antibiotic used to treat a wide range of bacterial infections, including respiratory, enteric and genitourinary infections. It is related to erythromycin, and is part of the azalide subclass of macrolides. It contains a 15-membered ring with a methyl-substituted nitrogen at the 9a position that prevents it from being broken down in the body. The FDA approved azithromycin in 1991 and in 2020, a French study found that a combination of azithromycin and hydroxychloroquine could be used to treat COVID-19. However
Zithromax
is the brand name
Zithromax Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Zithromax
Azithromycin
1994
541
Approved as Treatment by the FDA
Azithromycin, otherwise called Zithromax, is approved by the FDA for 32 uses including Bacterial Sinusitis and Sinusitis .
Bacterial Sinusitis
Sinusitis
Haemophilus Influenzae Infections
Genus Chlamydia
patients appropriate for oral therapy
Tonsillitis bacterial
genital ulcers caused by haemophilus ducreyi infection
Acute Otitis Media (AOM)
Streptococcus pyogenes
Streptococcal Pharyngitis
Tonsillitis streptococcal
unable to prescribe first line therapy for streptococcus pyogenes tonsillitis
Tonsillitis
Haemophilus ducreyi infection
Moraxella Catarrhalis Infection
Community Acquired Pneumonia (CAP)
Moraxella catarrhalis
ABDIC protocol
Adults
Streptococcus Pneumoniae Infections
Adult Patients
Genital Ulcer Disease (GUD)
Communicable Diseases
Staphylococcus (S.) Aureus Infection
Pneumococcal Infections
Pneumonia, Mycoplasma
Tonsillitis
Pediatric Patients
Otitis
Sore Throat
Streptococcus pyogenes
Streptococcus Agalactiae Infection
Effectiveness
How Zithromax Affects Patients
Macrolides are a type of drug used to treat bacterial infections by stopping the bacteria from growing and making proteins. Azithromycin has extra qualities that can help with respiratory diseases, and is sometimes used to treat these conditions.
How Zithromax works in the body
Azithromycin works by binding to the ribosomal proteins of bacteria, preventing them from making proteins. This stops bacteria from replicating and helps to control various bacterial infections.Azithromycin is more stable than other antibiotics, so it stays in the body longer and builds up higher concentrations in the tissues. This makes it more effective at fighting bacterial infections.
When to interrupt dosage
The quantity of Zithromax is contingent upon the diagnosed condition, including Streptococcus Agalactiae Infection, Chlamydia trachomatis and Genus Chlamydia. The measure of dosage is outlined in the table below, based on the route of administration.
Condition
Dosage
Administration
Streptococcus Agalactiae Infection
, 600.0 mg, 100.0 mg/mL, 500.0 mg, 10.0 mg/mL, 200.0 mg/mL, 500.0 mg/mL, 250.0 mg, 1000.0 mg, 50.0 mg/mL, 2000.0 mg, 1.0 %, 90.0 mg/mL, 120.0 mg/mL, 250.0 mg/mL
Oral, , Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Tablet, Tablet - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Powder, for suspension - Oral, Powder, for suspension, Injection, Injection - Intravenous, Powder, for solution - Oral, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Oral, Granule, for suspension, extended release - Oral, Granule, for suspension, extended release, Solution - Ophthalmic, Solution, For suspension, For suspension - Oral, Powder, for suspension - Parenteral, Parenteral, Suspension - Oral, Suspension, Tablet, coated, Tablet, coated - Oral
Urethritis
, 600.0 mg, 100.0 mg/mL, 500.0 mg, 10.0 mg/mL, 200.0 mg/mL, 500.0 mg/mL, 250.0 mg, 1000.0 mg, 50.0 mg/mL, 2000.0 mg, 1.0 %, 90.0 mg/mL, 120.0 mg/mL, 250.0 mg/mL
Oral, , Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Tablet, Tablet - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Powder, for suspension - Oral, Powder, for suspension, Injection, Injection - Intravenous, Powder, for solution - Oral, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Oral, Granule, for suspension, extended release - Oral, Granule, for suspension, extended release, Solution - Ophthalmic, Solution, For suspension, For suspension - Oral, Powder, for suspension - Parenteral, Parenteral, Suspension - Oral, Suspension, Tablet, coated, Tablet, coated - Oral
Chancroid
, 600.0 mg, 100.0 mg/mL, 500.0 mg, 10.0 mg/mL, 200.0 mg/mL, 500.0 mg/mL, 250.0 mg, 1000.0 mg, 50.0 mg/mL, 2000.0 mg, 1.0 %, 90.0 mg/mL, 120.0 mg/mL, 250.0 mg/mL
Oral, , Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Tablet, Tablet - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Powder, for suspension - Oral, Powder, for suspension, Injection, Injection - Intravenous, Powder, for solution - Oral, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Oral, Granule, for suspension, extended release - Oral, Granule, for suspension, extended release, Solution - Ophthalmic, Solution, For suspension, For suspension - Oral, Powder, for suspension - Parenteral, Parenteral, Suspension - Oral, Suspension, Tablet, coated, Tablet, coated - Oral
Conjunctivitis, Bacterial
, 600.0 mg, 100.0 mg/mL, 500.0 mg, 10.0 mg/mL, 200.0 mg/mL, 500.0 mg/mL, 250.0 mg, 1000.0 mg, 50.0 mg/mL, 2000.0 mg, 1.0 %, 90.0 mg/mL, 120.0 mg/mL, 250.0 mg/mL
Oral, , Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Tablet, Tablet - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Powder, for suspension - Oral, Powder, for suspension, Injection, Injection - Intravenous, Powder, for solution - Oral, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Oral, Granule, for suspension, extended release - Oral, Granule, for suspension, extended release, Solution - Ophthalmic, Solution, For suspension, For suspension - Oral, Powder, for suspension - Parenteral, Parenteral, Suspension - Oral, Suspension, Tablet, coated, Tablet, coated - Oral
Communicable Diseases
, 600.0 mg, 100.0 mg/mL, 500.0 mg, 10.0 mg/mL, 200.0 mg/mL, 500.0 mg/mL, 250.0 mg, 1000.0 mg, 50.0 mg/mL, 2000.0 mg, 1.0 %, 90.0 mg/mL, 120.0 mg/mL, 250.0 mg/mL
Oral, , Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Tablet, Tablet - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Powder, for suspension - Oral, Powder, for suspension, Injection, Injection - Intravenous, Powder, for solution - Oral, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Oral, Granule, for suspension, extended release - Oral, Granule, for suspension, extended release, Solution - Ophthalmic, Solution, For suspension, For suspension - Oral, Powder, for suspension - Parenteral, Parenteral, Suspension - Oral, Suspension, Tablet, coated, Tablet, coated - Oral
Otitis
, 600.0 mg, 100.0 mg/mL, 500.0 mg, 10.0 mg/mL, 200.0 mg/mL, 500.0 mg/mL, 250.0 mg, 1000.0 mg, 50.0 mg/mL, 2000.0 mg, 1.0 %, 90.0 mg/mL, 120.0 mg/mL, 250.0 mg/mL
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Tonsillitis
, 600.0 mg, 100.0 mg/mL, 500.0 mg, 10.0 mg/mL, 200.0 mg/mL, 500.0 mg/mL, 250.0 mg, 1000.0 mg, 50.0 mg/mL, 2000.0 mg, 1.0 %, 90.0 mg/mL, 120.0 mg/mL, 250.0 mg/mL
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Chlamydia trachomatis
, 600.0 mg, 100.0 mg/mL, 500.0 mg, 10.0 mg/mL, 200.0 mg/mL, 500.0 mg/mL, 250.0 mg, 1000.0 mg, 50.0 mg/mL, 2000.0 mg, 1.0 %, 90.0 mg/mL, 120.0 mg/mL, 250.0 mg/mL
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Genus Chlamydia
, 600.0 mg, 100.0 mg/mL, 500.0 mg, 10.0 mg/mL, 200.0 mg/mL, 500.0 mg/mL, 250.0 mg, 1000.0 mg, 50.0 mg/mL, 2000.0 mg, 1.0 %, 90.0 mg/mL, 120.0 mg/mL, 250.0 mg/mL
Oral, , Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Tablet, Tablet - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Powder, for suspension - Oral, Powder, for suspension, Injection, Injection - Intravenous, Powder, for solution - Oral, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Oral, Granule, for suspension, extended release - Oral, Granule, for suspension, extended release, Solution - Ophthalmic, Solution, For suspension, For suspension - Oral, Powder, for suspension - Parenteral, Parenteral, Suspension - Oral, Suspension, Tablet, coated, Tablet, coated - Oral
Genital Ulcer Disease (GUD)
, 600.0 mg, 100.0 mg/mL, 500.0 mg, 10.0 mg/mL, 200.0 mg/mL, 500.0 mg/mL, 250.0 mg, 1000.0 mg, 50.0 mg/mL, 2000.0 mg, 1.0 %, 90.0 mg/mL, 120.0 mg/mL, 250.0 mg/mL
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Haemophilus ducreyi infection
, 600.0 mg, 100.0 mg/mL, 500.0 mg, 10.0 mg/mL, 200.0 mg/mL, 500.0 mg/mL, 250.0 mg, 1000.0 mg, 50.0 mg/mL, 2000.0 mg, 1.0 %, 90.0 mg/mL, 120.0 mg/mL, 250.0 mg/mL
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Streptococcus pyogenes
, 600.0 mg, 100.0 mg/mL, 500.0 mg, 10.0 mg/mL, 200.0 mg/mL, 500.0 mg/mL, 250.0 mg, 1000.0 mg, 50.0 mg/mL, 2000.0 mg, 1.0 %, 90.0 mg/mL, 120.0 mg/mL, 250.0 mg/mL
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Moraxella catarrhalis
, 600.0 mg, 100.0 mg/mL, 500.0 mg, 10.0 mg/mL, 200.0 mg/mL, 500.0 mg/mL, 250.0 mg, 1000.0 mg, 50.0 mg/mL, 2000.0 mg, 1.0 %, 90.0 mg/mL, 120.0 mg/mL, 250.0 mg/mL
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Uterine Cervicitis
, 600.0 mg, 100.0 mg/mL, 500.0 mg, 10.0 mg/mL, 200.0 mg/mL, 500.0 mg/mL, 250.0 mg, 1000.0 mg, 50.0 mg/mL, 2000.0 mg, 1.0 %, 90.0 mg/mL, 120.0 mg/mL, 250.0 mg/mL
Oral, , Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Tablet, Tablet - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Powder, for suspension - Oral, Powder, for suspension, Injection, Injection - Intravenous, Powder, for solution - Oral, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Oral, Granule, for suspension, extended release - Oral, Granule, for suspension, extended release, Solution - Ophthalmic, Solution, For suspension, For suspension - Oral, Powder, for suspension - Parenteral, Parenteral, Suspension - Oral, Suspension, Tablet, coated, Tablet, coated - Oral
Sinusitis
, 600.0 mg, 100.0 mg/mL, 500.0 mg, 10.0 mg/mL, 200.0 mg/mL, 500.0 mg/mL, 250.0 mg, 1000.0 mg, 50.0 mg/mL, 2000.0 mg, 1.0 %, 90.0 mg/mL, 120.0 mg/mL, 250.0 mg/mL
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Adult Patients
, 600.0 mg, 100.0 mg/mL, 500.0 mg, 10.0 mg/mL, 200.0 mg/mL, 500.0 mg/mL, 250.0 mg, 1000.0 mg, 50.0 mg/mL, 2000.0 mg, 1.0 %, 90.0 mg/mL, 120.0 mg/mL, 250.0 mg/mL
Oral, , Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Tablet, Tablet - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Powder, for suspension - Oral, Powder, for suspension, Injection, Injection - Intravenous, Powder, for solution - Oral, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Oral, Granule, for suspension, extended release - Oral, Granule, for suspension, extended release, Solution - Ophthalmic, Solution, For suspension, For suspension - Oral, Powder, for suspension - Parenteral, Parenteral, Suspension - Oral, Suspension, Tablet, coated, Tablet, coated - Oral
Tonsillitis
, 600.0 mg, 100.0 mg/mL, 500.0 mg, 10.0 mg/mL, 200.0 mg/mL, 500.0 mg/mL, 250.0 mg, 1000.0 mg, 50.0 mg/mL, 2000.0 mg, 1.0 %, 90.0 mg/mL, 120.0 mg/mL, 250.0 mg/mL
Oral, , Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Tablet, Tablet - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Powder, for suspension - Oral, Powder, for suspension, Injection, Injection - Intravenous, Powder, for solution - Oral, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Oral, Granule, for suspension, extended release - Oral, Granule, for suspension, extended release, Solution - Ophthalmic, Solution, For suspension, For suspension - Oral, Powder, for suspension - Parenteral, Parenteral, Suspension - Oral, Suspension, Tablet, coated, Tablet, coated - Oral
Bacterial conjunctivitis
, 600.0 mg, 100.0 mg/mL, 500.0 mg, 10.0 mg/mL, 200.0 mg/mL, 500.0 mg/mL, 250.0 mg, 1000.0 mg, 50.0 mg/mL, 2000.0 mg, 1.0 %, 90.0 mg/mL, 120.0 mg/mL, 250.0 mg/mL
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Pneumonia, Mycoplasma
, 600.0 mg, 100.0 mg/mL, 500.0 mg, 10.0 mg/mL, 200.0 mg/mL, 500.0 mg/mL, 250.0 mg, 1000.0 mg, 50.0 mg/mL, 2000.0 mg, 1.0 %, 90.0 mg/mL, 120.0 mg/mL, 250.0 mg/mL
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Communicable Diseases
, 600.0 mg, 100.0 mg/mL, 500.0 mg, 10.0 mg/mL, 200.0 mg/mL, 500.0 mg/mL, 250.0 mg, 1000.0 mg, 50.0 mg/mL, 2000.0 mg, 1.0 %, 90.0 mg/mL, 120.0 mg/mL, 250.0 mg/mL
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Warnings
Zithromax Contraindications
Condition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Azithromycin may interact with Pulse Frequency
Jaundice, Obstructive
Do Not Combine
prior azithromycin use
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Azithromycin may interact with Pulse Frequency
Severe Hypersensitivity Reactions
Do Not Combine
Azithromycin may interact with Pulse Frequency
Severe Hypersensitivity Reactions
Do Not Combine
Azithromycin may interact with Pulse Frequency
There are 20 known major drug interactions with Zithromax.
Common Zithromax Drug Interactions
Drug Name
Risk Level
Description
Anagrelide
Major
The risk or severity of QTc prolongation can be increased when Azithromycin is combined with Anagrelide.
Arsenic trioxide
Major
The risk or severity of QTc prolongation can be increased when Azithromycin is combined with Arsenic trioxide.
Artemether
Major
The risk or severity of QTc prolongation can be increased when Azithromycin is combined with Artemether.
Asenapine
Major
The risk or severity of QTc prolongation can be increased when Azithromycin is combined with Asenapine.
Astemizole
Major
The risk or severity of QTc prolongation can be increased when Azithromycin is combined with Astemizole.
Zithromax Toxicity & Overdose Risk
In rats, the lowest dose of azithromycin that causes toxicity is over 2000mk/kg. This drug could potentially cause heart rhythm problems and hearing loss, and has been linked to macrolide resistance. Liver and kidney damage have been reported in rare cases. Azithromycin is a pregnancy category B drug, meaning it has not been proven to be harmful to a fetus, but should be used with caution if pregnant. This drug may also be found in breast milk, so caution should be taken when nursing. Animal studies have not found any evidence of cancer or fertility problems caused by azithromycin.
Zithromax Novel Uses: Which Conditions Have a Clinical Trial Featuring Zithromax?
Currently, 9 active studies are examining the possibility of administering Zithromax for the management of Moraxella Catarrhalis Infection, Staphylococcus (S.) Aureus Infection and Communicable Diseases.
Condition
Clinical Trials
Trial Phases
Sinusitis
0 Actively Recruiting
Communicable Diseases
0 Actively Recruiting
Staphylococcus (S.) Aureus Infection
2 Actively Recruiting
Phase 4, Phase 1
Conjunctivitis, Bacterial
0 Actively Recruiting
Streptococcus pyogenes
0 Actively Recruiting
Moraxella catarrhalis
0 Actively Recruiting
Streptococcus Agalactiae Infection
0 Actively Recruiting
Haemophilus Influenzae Infections
0 Actively Recruiting
Uterine Cervicitis
0 Actively Recruiting
Genital Ulcer Disease (GUD)
0 Actively Recruiting
unable to prescribe first line therapy for streptococcus pyogenes tonsillitis
0 Actively Recruiting
Bacterial conjunctivitis
0 Actively Recruiting
Streptococcus pyogenes
0 Actively Recruiting
Diarrhea
0 Actively Recruiting
Tonsillitis
0 Actively Recruiting
Communicable Diseases
0 Actively Recruiting
Pneumococcal Infections
0 Actively Recruiting
Pediatric Patients
0 Actively Recruiting
Adult Patients
0 Actively Recruiting
Chancroid
0 Actively Recruiting
Zithromax Reviews: What are patients saying about Zithromax?
5
Patient Review
3/20/2021
Zithromax for Bacterial Infection with Chronic Bronchitis
5
Patient Review
2/15/2021
Zithromax for Acute Bacterial Infection of the Sinuses
5
Patient Review
1/10/2022
Zithromax for Infection of the Middle Ear caused by Streptococcus
5
Patient Review
2/15/2021
Zithromax for Acute Bacterial Infection of the Sinuses
5
Patient Review
3/20/2021
Zithromax for Bacterial Infection with Chronic Bronchitis
5
Patient Review
1/10/2022
Zithromax for Infection of the Middle Ear caused by Streptococcus
4.7
Patient Review
2/8/2021
Zithromax for Acute Bacterial Infection of the Sinuses
4.7
Patient Review
2/8/2021
Zithromax for Acute Bacterial Infection of the Sinuses
4
Patient Review
3/30/2021
Zithromax for Bacterial Infection with Chronic Bronchitis
4
Patient Review
12/3/2019
Zithromax for Bacterial Infection with Chronic Bronchitis
4
Patient Review
12/3/2019
Zithromax for Bacterial Infection with Chronic Bronchitis
4
Patient Review
3/30/2021
Zithromax for Bacterial Infection with Chronic Bronchitis
3.7
Patient Review
4/13/2022
Zithromax for Chlamydia Trachomatis Infection of Female Pelvic Organs
3.7
Patient Review
4/13/2022
Zithromax for Chlamydia Trachomatis Infection of Female Pelvic Organs
3.3
Patient Review
1/4/2020
Zithromax for Strep Throat
3.3
Patient Review
1/4/2020
Zithromax for Strep Throat
3
Patient Review
1/7/2022
Zithromax for Acute Bacterial Infection of the Sinuses
3
Patient Review
1/7/2022
Zithromax for Acute Bacterial Infection of the Sinuses
2.7
Patient Review
5/27/2021
Zithromax for infection caused by bacteria
2.7
Patient Review
5/27/2021
Zithromax for infection caused by bacteria
2.3
Patient Review
6/14/2022
Zithromax for Bronchitis caused by the Bacteria Haemophilus Influenzae
2.3
Patient Review
6/14/2022
Zithromax for Bronchitis caused by the Bacteria Haemophilus Influenzae
1.7
Patient Review
5/11/2021
Zithromax for Acute Bacterial Infection of the Sinuses
1.7
Patient Review
5/11/2021
Zithromax for Acute Bacterial Infection of the Sinuses
1
Patient Review
11/17/2021
Zithromax for Middle Ear Infection
1
Patient Review
8/3/2019
Zithromax for infection caused by bacteria
1
Patient Review
11/17/2021
Zithromax for Middle Ear Infection
1
Patient Review
8/3/2019
Zithromax for infection caused by bacteria
Patient Q&A Section about zithromax
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
How fast does Zithromax work?
"The most common side effects of Zithromax are diarrhea, abdominal pain, nausea, and vomiting. Generally, it takes about five days for the full effect."
Answered by AI
What infections are treated with Zithromax?
"Otitis media, tonsillitis, laryngitis, bronchitis, pneumonia, and sinusitis are all caused by bacteria."
Answered by AI
What is Zithromax used for?
"Azithromycin is used to treat bacterial infections. It is a macrolide antibiotic that works by stopping the growth of bacteria. This medication will not work for viral infections (such as common cold, flu)."
Answered by AI
Is Zithromax a penicillin?
"Zithromax is not a penicillin. It is a macrolide antibiotic. Macrolides work by inhibiting protein synthesis and blocking the assembly of the 50S ribosomal subunit. This structure helps coordinate protein synthesis in cells."
Answered by AI