Tobradex

Bacteria, Cystic Fibrosis, Septicemia + 19 more
Treatment
9 Active Studies for Tobradex

What is Tobradex

TobramycinThe Generic name of this drug
Treatment SummaryTobramycin is an antibiotic medication used to treat a range of bacterial infections. It was developed in 1975 and can be administered by inhalation, injection, or applied directly to the eye. Tobramycin is especially effective against Pseudomonas aeruginosa, which is resistant to many other antibiotics. However, it can cause side effects such as kidney and hearing damage, so it is used cautiously.
Tobrexis the brand name
image of different drug pills on a surface
Tobradex Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Tobrex
Tobramycin
1981
166

Effectiveness

How Tobradex Affects PatientsTobramycin is an antibiotic used to treat different types of bacterial infections, such as those caused by _Enterobacteriaceae_, _Escherichia coli_, _Klebsiella pneumoniae_, and _Pseudomonas aeruginosa_. It also works on some Gram-positive bacteria, including methicillin-resistant (MRSA) and vancomycin-resistant strains. Taking too much tobramycin can cause kidney or ear damage, muscle weakness, or hearing loss in unborn babies. It can also cause allergic reactions, including severe skin reactions.
How Tobradex works in the bodyTobramycin works by damaging bacteria's cell membranes and preventing them from making proteins. It does this by binding to the cell's ribosome, which is responsible for making proteins. This binding blocks the ribosome from making new proteins and also disrupts the cell membrane, which allows more of the tobramycin into the cell. Bacteria can build up a resistance to tobramycin by modifying the ribosome or the tobramycin itself, which makes the drug less effective. Tobramycin is only effective against certain types of bacteria, such as Gram-negative and some Gram-positive bacteria.

When to interrupt dosage

The advised dosage of Tobradex is reliant upon the diagnosed state, including Cystic Fibrosis (CF), steroid-responsive inflammation and Meningitis, Bacterial. The amount of dosage can be found in the table below, contingent upon the method of delivery.
Condition
Dosage
Administration
Urinary tract infection
, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Solution - Oral, Solution, Solution / drops, Solution / drops - Ophthalmic, Intravenous, Injection, solution - Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suspension, Suspension - Ophthalmic, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Respiratory (inhalation), Solution - Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid, Liquid - Ophthalmic, Liquid - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Oral; Respiratory (inhalation), Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Inhalant, Inhalant - Respiratory (inhalation), Solution - Oral; Respiratory (inhalation)
concomitant use of NSAID
, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Solution - Oral, Solution, Solution / drops, Solution / drops - Ophthalmic, Intravenous, Injection, solution - Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suspension, Suspension - Ophthalmic, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Respiratory (inhalation), Solution - Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid, Liquid - Ophthalmic, Liquid - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Oral; Respiratory (inhalation), Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Inhalant, Inhalant - Respiratory (inhalation), Solution - Oral; Respiratory (inhalation)
steroid-responsive inflammation
, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Solution - Oral, Solution, Solution / drops, Solution / drops - Ophthalmic, Intravenous, Injection, solution - Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suspension, Suspension - Ophthalmic, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Respiratory (inhalation), Solution - Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid, Liquid - Ophthalmic, Liquid - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Oral; Respiratory (inhalation), Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Inhalant, Inhalant - Respiratory (inhalation), Solution - Oral; Respiratory (inhalation)
Eye Infections, Bacterial
, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Solution - Oral, Solution, Solution / drops, Solution / drops - Ophthalmic, Intravenous, Injection, solution - Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suspension, Suspension - Ophthalmic, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Respiratory (inhalation), Solution - Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid, Liquid - Ophthalmic, Liquid - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Oral; Respiratory (inhalation), Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Inhalant, Inhalant - Respiratory (inhalation), Solution - Oral; Respiratory (inhalation)
Adrenal Cortex Hormones
, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Solution - Oral, Solution, Solution / drops, Solution / drops - Ophthalmic, Intravenous, Injection, solution - Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suspension, Suspension - Ophthalmic, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Respiratory (inhalation), Solution - Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid, Liquid - Ophthalmic, Liquid - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Oral; Respiratory (inhalation), Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Inhalant, Inhalant - Respiratory (inhalation), Solution - Oral; Respiratory (inhalation)
ear infection-not otherwise specified caused by susceptible bacteria
, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Solution - Oral, Solution, Solution / drops, Solution / drops - Ophthalmic, Intravenous, Injection, solution - Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suspension, Suspension - Ophthalmic, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Respiratory (inhalation), Solution - Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid, Liquid - Ophthalmic, Liquid - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Oral; Respiratory (inhalation), Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Inhalant, Inhalant - Respiratory (inhalation), Solution - Oral; Respiratory (inhalation)
External auditory canal structure
, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Solution - Oral, Solution, Solution / drops, Solution / drops - Ophthalmic, Intravenous, Injection, solution - Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suspension, Suspension - Ophthalmic, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Respiratory (inhalation), Solution - Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid, Liquid - Ophthalmic, Liquid - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Oral; Respiratory (inhalation), Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Inhalant, Inhalant - Respiratory (inhalation), Solution - Oral; Respiratory (inhalation)
FEV1 <25% predicted
, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Solution - Oral, Solution, Solution / drops, Solution / drops - Ophthalmic, Intravenous, Injection, solution - Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suspension, Suspension - Ophthalmic, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Respiratory (inhalation), Solution - Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid, Liquid - Ophthalmic, Liquid - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Oral; Respiratory (inhalation), Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Inhalant, Inhalant - Respiratory (inhalation), Solution - Oral; Respiratory (inhalation)
FEV1 >80% predicted
, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Solution - Oral, Solution, Solution / drops, Solution / drops - Ophthalmic, Intravenous, Injection, solution - Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suspension, Suspension - Ophthalmic, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Respiratory (inhalation), Solution - Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid, Liquid - Ophthalmic, Liquid - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Oral; Respiratory (inhalation), Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Inhalant, Inhalant - Respiratory (inhalation), Solution - Oral; Respiratory (inhalation)
Bacteria
, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Solution - Oral, Solution, Solution / drops, Solution / drops - Ophthalmic, Intravenous, Injection, solution - Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suspension, Suspension - Ophthalmic, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Respiratory (inhalation), Solution - Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid, Liquid - Ophthalmic, Liquid - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Oral; Respiratory (inhalation), Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Inhalant, Inhalant - Respiratory (inhalation), Solution - Oral; Respiratory (inhalation)
Cystic Fibrosis
, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Solution - Oral, Solution, Solution / drops, Solution / drops - Ophthalmic, Intravenous, Injection, solution - Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suspension, Suspension - Ophthalmic, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Respiratory (inhalation), Solution - Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid, Liquid - Ophthalmic, Liquid - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Oral; Respiratory (inhalation), Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Inhalant, Inhalant - Respiratory (inhalation), Solution - Oral; Respiratory (inhalation)
Septicemia
, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Solution - Oral, Solution, Solution / drops, Solution / drops - Ophthalmic, Intravenous, Injection, solution - Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suspension, Suspension - Ophthalmic, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Respiratory (inhalation), Solution - Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid, Liquid - Ophthalmic, Liquid - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Oral; Respiratory (inhalation), Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Inhalant, Inhalant - Respiratory (inhalation), Solution - Oral; Respiratory (inhalation)
ocular bacterial infections
, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Solution - Oral, Solution, Solution / drops, Solution / drops - Ophthalmic, Intravenous, Injection, solution - Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suspension, Suspension - Ophthalmic, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Respiratory (inhalation), Solution - Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid, Liquid - Ophthalmic, Liquid - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Oral; Respiratory (inhalation), Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Inhalant, Inhalant - Respiratory (inhalation), Solution - Oral; Respiratory (inhalation)
Bacterial Infections
, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Solution - Oral, Solution, Solution / drops, Solution / drops - Ophthalmic, Intravenous, Injection, solution - Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suspension, Suspension - Ophthalmic, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Respiratory (inhalation), Solution - Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid, Liquid - Ophthalmic, Liquid - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Oral; Respiratory (inhalation), Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Inhalant, Inhalant - Respiratory (inhalation), Solution - Oral; Respiratory (inhalation)
Eye Infections
, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Solution - Oral, Solution, Solution / drops, Solution / drops - Ophthalmic, Intravenous, Injection, solution - Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suspension, Suspension - Ophthalmic, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Respiratory (inhalation), Solution - Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid, Liquid - Ophthalmic, Liquid - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Oral; Respiratory (inhalation), Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Inhalant, Inhalant - Respiratory (inhalation), Solution - Oral; Respiratory (inhalation)
Ocular Inflammation
, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Solution - Oral, Solution, Solution / drops, Solution / drops - Ophthalmic, Intravenous, Injection, solution - Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suspension, Suspension - Ophthalmic, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Respiratory (inhalation), Solution - Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid, Liquid - Ophthalmic, Liquid - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Oral; Respiratory (inhalation), Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Inhalant, Inhalant - Respiratory (inhalation), Solution - Oral; Respiratory (inhalation)
Cystic Fibrosis (CF)
, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Solution - Oral, Solution, Solution / drops, Solution / drops - Ophthalmic, Intravenous, Injection, solution - Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suspension, Suspension - Ophthalmic, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Respiratory (inhalation), Solution - Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid, Liquid - Ophthalmic, Liquid - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Oral; Respiratory (inhalation), Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Inhalant, Inhalant - Respiratory (inhalation), Solution - Oral; Respiratory (inhalation)
Bone Infection
, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Solution - Oral, Solution, Solution / drops, Solution / drops - Ophthalmic, Intravenous, Injection, solution - Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suspension, Suspension - Ophthalmic, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Respiratory (inhalation), Solution - Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid, Liquid - Ophthalmic, Liquid - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Oral; Respiratory (inhalation), Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Inhalant, Inhalant - Respiratory (inhalation), Solution - Oral; Respiratory (inhalation)
Intraabdominal Infections
, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Solution - Oral, Solution, Solution / drops, Solution / drops - Ophthalmic, Intravenous, Injection, solution - Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suspension, Suspension - Ophthalmic, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Respiratory (inhalation), Solution - Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid, Liquid - Ophthalmic, Liquid - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Oral; Respiratory (inhalation), Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Inhalant, Inhalant - Respiratory (inhalation), Solution - Oral; Respiratory (inhalation)
Meningitis, Bacterial
, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Solution - Oral, Solution, Solution / drops, Solution / drops - Ophthalmic, Intravenous, Injection, solution - Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suspension, Suspension - Ophthalmic, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Respiratory (inhalation), Solution - Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid, Liquid - Ophthalmic, Liquid - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Oral; Respiratory (inhalation), Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Inhalant, Inhalant - Respiratory (inhalation), Solution - Oral; Respiratory (inhalation)

Warnings

Tobradex Contraindications
Condition
Risk Level
Notes
Pulse Frequency
Do Not Combine
There are 20 known major drug interactions with Tobradex.
Common Tobradex Drug Interactions
Drug Name
Risk Level
Description
Neomycin
Major
The risk or severity of nephrotoxicity can be increased when Tobramycin is combined with Neomycin.
Tenofovir
Major
Tobramycin may increase the nephrotoxic activities of Tenofovir.
Tenofovir alafenamide
Major
Tobramycin may increase the nephrotoxic activities of Tenofovir alafenamide.
Tenofovir disoproxil
Major
Tobramycin may increase the nephrotoxic activities of Tenofovir disoproxil.
Vibrio cholerae CVD 103-HgR strain live antigen
Major
The therapeutic efficacy of Vibrio cholerae CVD 103-HgR strain live antigen can be decreased when used in combination with Tobramycin.
Tobradex Toxicity & Overdose RiskTobramycin can cause serious side effects if taken in large doses, such as damage to the kidneys or ears, nerve or muscle problems, or difficulty breathing. Treatment for an overdose of tobramycin focuses on managing the symptoms and hemodialysis may be used to clear excess of the drug from the body. Taking tobramycin by accident is unlikely to cause an overdose, as it is not well absorbed in the digestive system. Animal studies have found that the toxic dose for mice and rats to be between 367-1030 mg/kg when administered through injection and more than 7500 mg/kg when taken orally.
image of a doctor in a lab doing drug, clinical research

Tobradex Novel Uses: Which Conditions Have a Clinical Trial Featuring Tobradex?

At present, 8 active trials are investigating the potential of Tobradex to alleviate Cystic Fibrosis, Bacterial Ocular Infections and Bacterial Infections.
Condition
Clinical Trials
Trial Phases
Cystic Fibrosis
0 Actively Recruiting
Septicemia
0 Actively Recruiting
ear infection-not otherwise specified caused by susceptible bacteria
0 Actively Recruiting
Eye Infections, Bacterial
0 Actively Recruiting
Bacteria
0 Actively Recruiting
Bacterial Infections
1 Actively Recruiting
Phase 4
Urinary tract infection
0 Actively Recruiting
External auditory canal structure
0 Actively Recruiting
concomitant use of NSAID
0 Actively Recruiting
Bacterial Peritonitis
0 Actively Recruiting
FEV1 >80% predicted
0 Actively Recruiting
FEV1 <25% predicted
0 Actively Recruiting
Eye Infections
1 Actively Recruiting
Phase 4
Intraabdominal Infections
3 Actively Recruiting
Not Applicable, Phase 4
steroid-responsive inflammation
0 Actively Recruiting
ocular bacterial infections
0 Actively Recruiting
Cystic Fibrosis (CF)
0 Actively Recruiting
Burkholderia Cepacia Infection
0 Actively Recruiting
Bone Infection
1 Actively Recruiting
Phase 2
Adrenal Cortex Hormones
0 Actively Recruiting

Tobradex Reviews: What are patients saying about Tobradex?

5Patient Review
1/9/2010
Tobradex for Bacterial Infection of the Eyelid
I was amazed at how quickly this treatment worked. I had been dealing with a lot of pain for months, and after starting this medication, it went away almost immediately.
5Patient Review
1/15/2014
Tobradex for Infection Confined to the Surface of the Eye
My optometrist suggest this for my corneal infection and it worked like a charm!
5Patient Review
8/3/2010
Tobradex for Pink Eye from Bacterial Infection
I slept in my contacts and bacteria got into my eyes, which made it difficult for me to be exposed to any light whatsoever.
5Patient Review
4/7/2013
Tobradex for Scratch Wound on Cornea
Trobadex ointment is a complete life saver. I had an old tube from when I used it for pink eye and applied it to my dog scratch wound before bed. The pain was completely gone by the next morning!
4.7Patient Review
6/24/2011
Tobradex for Inflammation of Eyelid Edges and the Lining of the Eye
Although it caused my vision to blur, this drug was very effective in reducing inflammation and irritation.
3.7Patient Review
2/9/2010
Tobradex for Inflammation of Eyelid Edges and the Lining of the Eye
It took a little bit of research to understand how to properly use this cream, but it was well worth it. The pain and swelling in my eyelid went away within just three days.
3.3Patient Review
1/16/2020
Tobradex for Infection Confined to the Surface of the Eye
I was prescribed this for an infection, but unfortunately it gave me terrible diarrhea. It did help with the itchiness though.
1.7Patient Review
7/7/2011
Tobradex for Bacterial Infection of the Eyelid
My son has been taking this perscription since July 4, 2011. He is blind and started with 1 drop in right eye every 3 hours for 2 weeks, then moved up to 1 drip 4 times daily for 2 weeks.
1.3Patient Review
4/6/2015
Tobradex for Inflammation of the Eye
I took this for A.S related iritis, but unfortunately I'm allergic to one of the main ingredients (white petrolium jelly) and it just gave me a red puffy painful rash.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about tobradex

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How long can you use Tobradex eye drops?

"If you are an adult, put one drop of this medication into your conjunctival sac(s) every 4 to 6 hours while you are awake. For the first 24 to 48 hours, you may need to put a drop in every 2 hours while you are awake. Use this medication for 14 days, but do not use it for more than 24 days."

Answered by AI

How many times a day can I use Tobradex?

"Adults should use a 1/2-inch strip of ointment in the eye up to three or four times a day, and children's use and dose must be determined by a doctor."

Answered by AI

What is Tobradex used for?

"Tobradex Eye Drops are used to treat inflammation, corneal injury and bacterial infections in the external part of the eye. Your doctor will have examined your eye(s) and decided that Tobradex Eye Drops are the right medicine for you."

Answered by AI

Is Tobradex a steroid?

"The eye medication Tobradex, which is a combination of the steroid tobramycin and the antibiotic dexamethasone, is effective in treating eye inflammation and bacterial infections. However, if it is used for a long time, it can cause high eye pressure and eye injury."

Answered by AI

Clinical Trials for Tobradex

Have you considered Tobradex clinical trials? We made a collection of clinical trials featuring Tobradex, we think they might fit your search criteria.