Timoptic

Migraine, Open-angle glaucoma, prophylaxis of migraine headaches + 6 more
Treatment
20 Active Studies for Timoptic

What is Timoptic

TimololThe Generic name of this drug
Treatment SummaryTimolol is a medication used to lower pressure in the eyes and treat high blood pressure. It is available in eye drop solution or tablet form, and was approved by the FDA in 1978. There are various manufacturers of this drug, making it a popular choice for treating conditions such as glaucoma and hypertension.
Timopticis the brand name
Timoptic Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Timoptic
Timolol
1978
167

Effectiveness

How Timoptic Affects PatientsTimolol is a drug that can be used to quickly lower pressure inside the eyes, as well as reduce blood pressure, heart rate, and sympathetic activity. It starts working about 20 minutes after an ophthalmic dose and can last up to 24 hours if given in a 0.5% or 0.25% dose.
How Timoptic works in the bodyTimolol blocks certain receptors in the heart, blood vessels and bronchial muscles, which helps lower blood pressure. It also reduces the production of aqueous humor in the eye, likely by decreasing the blood supply to the ciliary body or interfering with prostaglandin synthesis.

When to interrupt dosage

The suggested measure of Timoptic is determined by the diagnosed condition, such as Open Angle Glaucoma, requiring additional or substitution treatment and Ocular Hypertension. The amount of dosage differs based on the method of administration (e.g. Ophthalmic or Solution, gel forming / drops) as shown in the table below.
Condition
Dosage
Administration
insufficient response to beta-blockers
5.0 mg/mL, , 5.0 mg, 10.0 mg, 20.0 mg, 2.5 mg/mL, 6.8 mg/mL, 6.83 mg/mL, 2.56 mg/mL, 5.12 mg/mL, 0.5 %, 0.25 %, 3.4 mg/mL, 0.1 mg/mL
, Ophthalmic, Solution, Solution - Ophthalmic, Oral, Tablet, Tablet - Oral, Solution / drops, Solution / drops - Ophthalmic, Solution, gel forming, extended release, Solution, gel forming, extended release - Ophthalmic, Liquid, Liquid - Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Suspension, Suspension - Ophthalmic, Solution, gel forming / drops, Solution, gel forming / drops - Ophthalmic
Migraine
5.0 mg/mL, , 5.0 mg, 10.0 mg, 20.0 mg, 2.5 mg/mL, 6.8 mg/mL, 6.83 mg/mL, 2.56 mg/mL, 5.12 mg/mL, 0.5 %, 0.25 %, 3.4 mg/mL, 0.1 mg/mL
, Ophthalmic, Solution, Solution - Ophthalmic, Oral, Tablet, Tablet - Oral, Solution / drops, Solution / drops - Ophthalmic, Solution, gel forming, extended release, Solution, gel forming, extended release - Ophthalmic, Liquid, Liquid - Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Suspension, Suspension - Ophthalmic, Solution, gel forming / drops, Solution, gel forming / drops - Ophthalmic
Open-angle glaucoma
5.0 mg/mL, , 5.0 mg, 10.0 mg, 20.0 mg, 2.5 mg/mL, 6.8 mg/mL, 6.83 mg/mL, 2.56 mg/mL, 5.12 mg/mL, 0.5 %, 0.25 %, 3.4 mg/mL, 0.1 mg/mL
, Ophthalmic, Solution, Solution - Ophthalmic, Oral, Tablet, Tablet - Oral, Solution / drops, Solution / drops - Ophthalmic, Solution, gel forming, extended release, Solution, gel forming, extended release - Ophthalmic, Liquid, Liquid - Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Suspension, Suspension - Ophthalmic, Solution, gel forming / drops, Solution, gel forming / drops - Ophthalmic
Ocular Hypertension
5.0 mg/mL, , 5.0 mg, 10.0 mg, 20.0 mg, 2.5 mg/mL, 6.8 mg/mL, 6.83 mg/mL, 2.56 mg/mL, 5.12 mg/mL, 0.5 %, 0.25 %, 3.4 mg/mL, 0.1 mg/mL
, Ophthalmic, Solution, Solution - Ophthalmic, Oral, Tablet, Tablet - Oral, Solution / drops, Solution / drops - Ophthalmic, Solution, gel forming, extended release, Solution, gel forming, extended release - Ophthalmic, Liquid, Liquid - Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Suspension, Suspension - Ophthalmic, Solution, gel forming / drops, Solution, gel forming / drops - Ophthalmic
inadequate response to other therapeutic measures
5.0 mg/mL, , 5.0 mg, 10.0 mg, 20.0 mg, 2.5 mg/mL, 6.8 mg/mL, 6.83 mg/mL, 2.56 mg/mL, 5.12 mg/mL, 0.5 %, 0.25 %, 3.4 mg/mL, 0.1 mg/mL
, Ophthalmic, Solution, Solution - Ophthalmic, Oral, Tablet, Tablet - Oral, Solution / drops, Solution / drops - Ophthalmic, Solution, gel forming, extended release, Solution, gel forming, extended release - Ophthalmic, Liquid, Liquid - Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Suspension, Suspension - Ophthalmic, Solution, gel forming / drops, Solution, gel forming / drops - Ophthalmic
prophylaxis of migraine headaches
5.0 mg/mL, , 5.0 mg, 10.0 mg, 20.0 mg, 2.5 mg/mL, 6.8 mg/mL, 6.83 mg/mL, 2.56 mg/mL, 5.12 mg/mL, 0.5 %, 0.25 %, 3.4 mg/mL, 0.1 mg/mL
, Ophthalmic, Solution, Solution - Ophthalmic, Oral, Tablet, Tablet - Oral, Solution / drops, Solution / drops - Ophthalmic, Solution, gel forming, extended release, Solution, gel forming, extended release - Ophthalmic, Liquid, Liquid - Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Suspension, Suspension - Ophthalmic, Solution, gel forming / drops, Solution, gel forming / drops - Ophthalmic
Open Angle Glaucoma
5.0 mg/mL, , 5.0 mg, 10.0 mg, 20.0 mg, 2.5 mg/mL, 6.8 mg/mL, 6.83 mg/mL, 2.56 mg/mL, 5.12 mg/mL, 0.5 %, 0.25 %, 3.4 mg/mL, 0.1 mg/mL
, Ophthalmic, Solution, Solution - Ophthalmic, Oral, Tablet, Tablet - Oral, Solution / drops, Solution / drops - Ophthalmic, Solution, gel forming, extended release, Solution, gel forming, extended release - Ophthalmic, Liquid, Liquid - Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Suspension, Suspension - Ophthalmic, Solution, gel forming / drops, Solution, gel forming / drops - Ophthalmic
requiring adjunctive or replacement therapy
5.0 mg/mL, , 5.0 mg, 10.0 mg, 20.0 mg, 2.5 mg/mL, 6.8 mg/mL, 6.83 mg/mL, 2.56 mg/mL, 5.12 mg/mL, 0.5 %, 0.25 %, 3.4 mg/mL, 0.1 mg/mL
, Ophthalmic, Solution, Solution - Ophthalmic, Oral, Tablet, Tablet - Oral, Solution / drops, Solution / drops - Ophthalmic, Solution, gel forming, extended release, Solution, gel forming, extended release - Ophthalmic, Liquid, Liquid - Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Suspension, Suspension - Ophthalmic, Solution, gel forming / drops, Solution, gel forming / drops - Ophthalmic
Increased Intra Ocular Pressure (IOP)
5.0 mg/mL, , 5.0 mg, 10.0 mg, 20.0 mg, 2.5 mg/mL, 6.8 mg/mL, 6.83 mg/mL, 2.56 mg/mL, 5.12 mg/mL, 0.5 %, 0.25 %, 3.4 mg/mL, 0.1 mg/mL
, Ophthalmic, Solution, Solution - Ophthalmic, Oral, Tablet, Tablet - Oral, Solution / drops, Solution / drops - Ophthalmic, Solution, gel forming, extended release, Solution, gel forming, extended release - Ophthalmic, Liquid, Liquid - Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Suspension, Suspension - Ophthalmic, Solution, gel forming / drops, Solution, gel forming / drops - Ophthalmic

Warnings

Timoptic has seven contraindications and should not be administered when experiencing any of the situations outlined in the following table.Timoptic Contraindications
Condition
Risk Level
Notes
Lung Diseases, Obstructive
Do Not Combine
Sinus Bradycardia
Do Not Combine
Shock, Cardiogenic
Do Not Combine
second or third degree AV block
Do Not Combine
Asthma
Do Not Combine
overt cardiac failure
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Timolol may interact with Pulse Frequency
There are 20 known major drug interactions with Timoptic.
Common Timoptic Drug Interactions
Drug Name
Risk Level
Description
4-Bromo-2,5-dimethoxyphenethylamine
Major
The therapeutic efficacy of 4-Bromo-2,5-dimethoxyphenethylamine can be decreased when used in combination with Timolol.
4-Methoxyamphetamine
Major
The therapeutic efficacy of 4-Methoxyamphetamine can be decreased when used in combination with Timolol.
Abediterol
Major
Timolol may decrease the bronchodilatory activities of Abediterol.
Adrafinil
Major
The therapeutic efficacy of Adrafinil can be decreased when used in combination with Timolol.
Agrostis gigantea pollen
Major
The risk of a hypersensitivity reaction to Agrostis gigantea pollen is increased when it is combined with Timolol.
Timoptic Toxicity & Overdose RiskThe toxic dose of timolol maleate in rats is 1028mg/kg and 1137mg/kg in mice. An overdose may cause dizziness, headaches, difficulty breathing, a slow heart rate, or even cardiac arrest. Dialysis can be used to reverse the effects of timolol overdose, although those with poor kidney function might not find it as effective.
image of a doctor in a lab doing drug, clinical research

Timoptic Novel Uses: Which Conditions Have a Clinical Trial Featuring Timoptic?

172 active trials are assessing the benefits of Timoptic in managing insufficient response to beta-blockers, insufficient response to other therapies and requiring adjunctive or replacement therapy.
Condition
Clinical Trials
Trial Phases
Increased Intra Ocular Pressure (IOP)
0 Actively Recruiting
Open-angle glaucoma
84 Actively Recruiting
Phase 3, Not Applicable, Phase 1, Phase 2, Phase 4, Early Phase 1
prophylaxis of migraine headaches
0 Actively Recruiting
requiring adjunctive or replacement therapy
0 Actively Recruiting
Migraine
52 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3, Phase 4, Early Phase 1
inadequate response to other therapeutic measures
0 Actively Recruiting
insufficient response to beta-blockers
0 Actively Recruiting
Ocular Hypertension
22 Actively Recruiting
Phase 1, Phase 2, Not Applicable, Phase 3, Phase 4
Open Angle Glaucoma
12 Actively Recruiting
Not Applicable, Phase 3, Phase 2

Timoptic Reviews: What are patients saying about Timoptic?

5Patient Review
7/20/2009
Timoptic for Closed Angle Glaucoma
I've been on this medication for several years and it's lowered my intraocular pressure from 28 to 16. No complaints here, just great results.
5Patient Review
2/3/2017
Timoptic for Wide-Angle Glaucoma
I've been using this medication for three years now, and it has really helped to improve my overall eye health. It's lowered my intraocular pressure (IOP) and prevented me from losing any more of my vision.
5Patient Review
1/3/2012
Timoptic for Increased Pressure in the Eye
I've been using this medication for nine months now, and my eye pressure has lowered from 28 to 18.
4Patient Review
4/18/2009
Timoptic for Closed Angle Glaucoma
So far, so good. I worry that my eyes will get used to it, and it wont work as well as it should.
3.7Patient Review
10/24/2009
Timoptic for High Eye Pressure or Glaucoma that May Worsen without Treatment
After taking this medication, I feel exhausted and like I need to take a nap.
3Patient Review
12/28/2015
Timoptic for High Eye Pressure or Glaucoma that May Worsen without Treatment
My doctor was pleased to see my blood pressure drop from 28 to 21 within two months. However, I started experiencing daily lethargy and extreme foot pain, cold feet and hands. When I reported these symptoms to him, he told me to stop taking the medication immediately. We are trying another drug but the foot pain has not subsided in 2 weeks.
2.3Patient Review
12/12/2010
Timoptic for Closed Angle Glaucoma
I've been using this treatment for a little over three months now. I had used it before but stopped because it burned, however other drugs haven't been effective so I had to start again. It's made my breathing more labored and still burns; on top of that, it also makes me nauseated. Hopefully I can find something else soon that will be more effective with fewer side effects.
2.3Patient Review
12/16/2013
Timoptic for Wide-Angle Glaucoma
Timolol Maleate was not effective in reducing my intraocular pressure. I've tried several other options with no success.
1.7Patient Review
5/29/2009
Timoptic for High Eye Pressure or Glaucoma that May Worsen without Treatment
I experienced worsening depression, feeling like my ears were clogged, and low blood pressure while taking this medication.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about timoptic

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are the side effects of Timoptic eye drops?

"If you experience any of the following side effects, notify your doctor or pharmacist: temporary blurred vision, temporary burning/stinging/itching/redness of the eye, watery eyes, dry eyes, feeling as if something is in the eye, or headache."

Answered by AI

What are side effects of timolol?

"You may experience some temporary side effects such as blurred vision, burning or stinging sensations in the eyes, watery eyes, dry eyes, the feeling that there is something in your eye, or a headache. If you notice any of these effects persisting or worsening, be sure to notify your doctor or pharmacist."

Answered by AI

Are timolol and Timoptic the same?

"The generic form of Timoptic is called timolol, and there is also a generic form of Xalatan."

Answered by AI

What is Timoptic eye drops used for?

"Timolol eye drops are used to treat increased pressure in the eye that is caused by open-angle glaucoma or a condition called ocular (eye) hypertension. This medicine is a beta-blocker."

Answered by AI

Clinical Trials for Timoptic

Have you considered Timoptic clinical trials? We made a collection of clinical trials featuring Timoptic, we think they might fit your search criteria.
Have you considered Timoptic clinical trials? We made a collection of clinical trials featuring Timoptic, we think they might fit your search criteria.
Have you considered Timoptic clinical trials? We made a collection of clinical trials featuring Timoptic, we think they might fit your search criteria.
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