Theo-Dur

Acute Bronchitis, Bronchial Spasm, Asthma + 8 more
Treatment
7 FDA approvals
20 Active Studies for Theo-Dur

What is Theo-Dur

TheophyllineThe Generic name of this drug
Treatment SummaryTheophylline is a drug derived from tea that has multiple effects on the body including increasing urine production, relaxing smooth muscle, and stimulating the heart, lungs, and central nervous system. It works by blocking enzyme phosphodiesterase, adenosine receptors, and activating histone deacetylase. It is sold under several brand names such as Uniphyl and Theochron and is most commonly used for asthma, bronchospasm, and chronic obstructive pulmonary disease (COPD).
Elixophyllinis the brand name
image of different drug pills on a surface
Theo-Dur Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Elixophyllin
Theophylline
1979
114

Approved as Treatment by the FDA

Theophylline, commonly known as Elixophyllin, is approved by the FDA for 7 uses like Chronic Bronchitis and Lung Disorder .
Chronic Bronchitis
Lung Disorder
Asthma
Asthma
Bronchitis, Chronic
Bronchoconstriction
Lung Diseases

Effectiveness

How Theo-Dur Affects PatientsTheophylline, which is similar to caffeine and theobromine, is used to treat asthma and other airway problems. It helps by relaxing the airway muscles and reducing the body's response to irritants.
How Theo-Dur works in the bodyTheophylline is a medication that helps to open up the airways and reduce the responsiveness of the airways to various triggers. It does this by blocking an enzyme that breaks down a molecule in the cells that help keep the airways relaxed. It also binds to a receptor in the airways and prevents it from tightening. In inflammatory states, it helps reduce inflammation by stopping the transcription of certain genes.

When to interrupt dosage

The proposed dosage of Theo-Dur is contingent upon the indicated condition, including Bronchodilation, Bronchoconstriction and Chronic Obstructive Pulmonary Disease (COPD). The amount of dosage differs, in line with the method of administration set forth in the table below.
Condition
Dosage
Administration
Chronic Obstructive Pulmonary Disease
, 8.0 mg/mL, 0.8 mg/mL, 1.6 mg/mL, 300.0 mg, 200.0 mg, 100.0 mg, 400.0 mg, 450.0 mg, 600.0 mg, 50.0 mg, 250.0 mg, 500.0 mg, 125.0 mg, 70.0 mg, 140.0 mg, 118.0 mg, 2.0 mg/mL, 4.0 mg/mL, 3.2 mg/mL, 175.0 mg, 65.0 mg, 75.0 mg, 350.0 mg, 130.0 mg, 0.4 mg/mL, 7.0 mg/mL
, Oral, Solution, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Capsule, extended release, Capsule, extended release - Oral, Kit, Elixir, Elixir - Oral, Syrup, Syrup - Oral, Capsule - Oral, Capsule, Injection, Injection - Intravenous, Solution - Intravenous
Airway secretion clearance therapy
, 8.0 mg/mL, 0.8 mg/mL, 1.6 mg/mL, 300.0 mg, 200.0 mg, 100.0 mg, 400.0 mg, 450.0 mg, 600.0 mg, 50.0 mg, 250.0 mg, 500.0 mg, 125.0 mg, 70.0 mg, 140.0 mg, 118.0 mg, 2.0 mg/mL, 4.0 mg/mL, 3.2 mg/mL, 175.0 mg, 65.0 mg, 75.0 mg, 350.0 mg, 130.0 mg, 0.4 mg/mL, 7.0 mg/mL
, Oral, Solution, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Capsule, extended release, Capsule, extended release - Oral, Kit, Elixir, Elixir - Oral, Syrup, Syrup - Oral, Capsule - Oral, Capsule, Injection, Injection - Intravenous, Solution - Intravenous
Bronchitis, Chronic
, 8.0 mg/mL, 0.8 mg/mL, 1.6 mg/mL, 300.0 mg, 200.0 mg, 100.0 mg, 400.0 mg, 450.0 mg, 600.0 mg, 50.0 mg, 250.0 mg, 500.0 mg, 125.0 mg, 70.0 mg, 140.0 mg, 118.0 mg, 2.0 mg/mL, 4.0 mg/mL, 3.2 mg/mL, 175.0 mg, 65.0 mg, 75.0 mg, 350.0 mg, 130.0 mg, 0.4 mg/mL, 7.0 mg/mL
, Oral, Solution, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Capsule, extended release, Capsule, extended release - Oral, Kit, Elixir, Elixir - Oral, Syrup, Syrup - Oral, Capsule - Oral, Capsule, Injection, Injection - Intravenous, Solution - Intravenous
Acute Bronchitis
, 8.0 mg/mL, 0.8 mg/mL, 1.6 mg/mL, 300.0 mg, 200.0 mg, 100.0 mg, 400.0 mg, 450.0 mg, 600.0 mg, 50.0 mg, 250.0 mg, 500.0 mg, 125.0 mg, 70.0 mg, 140.0 mg, 118.0 mg, 2.0 mg/mL, 4.0 mg/mL, 3.2 mg/mL, 175.0 mg, 65.0 mg, 75.0 mg, 350.0 mg, 130.0 mg, 0.4 mg/mL, 7.0 mg/mL
, Oral, Solution, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Capsule, extended release, Capsule, extended release - Oral, Kit, Elixir, Elixir - Oral, Syrup, Syrup - Oral, Capsule - Oral, Capsule, Injection, Injection - Intravenous, Solution - Intravenous
Bronchial Spasm
, 8.0 mg/mL, 0.8 mg/mL, 1.6 mg/mL, 300.0 mg, 200.0 mg, 100.0 mg, 400.0 mg, 450.0 mg, 600.0 mg, 50.0 mg, 250.0 mg, 500.0 mg, 125.0 mg, 70.0 mg, 140.0 mg, 118.0 mg, 2.0 mg/mL, 4.0 mg/mL, 3.2 mg/mL, 175.0 mg, 65.0 mg, 75.0 mg, 350.0 mg, 130.0 mg, 0.4 mg/mL, 7.0 mg/mL
, Oral, Solution, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Capsule, extended release, Capsule, extended release - Oral, Kit, Elixir, Elixir - Oral, Syrup, Syrup - Oral, Capsule - Oral, Capsule, Injection, Injection - Intravenous, Solution - Intravenous
Asthma
, 8.0 mg/mL, 0.8 mg/mL, 1.6 mg/mL, 300.0 mg, 200.0 mg, 100.0 mg, 400.0 mg, 450.0 mg, 600.0 mg, 50.0 mg, 250.0 mg, 500.0 mg, 125.0 mg, 70.0 mg, 140.0 mg, 118.0 mg, 2.0 mg/mL, 4.0 mg/mL, 3.2 mg/mL, 175.0 mg, 65.0 mg, 75.0 mg, 350.0 mg, 130.0 mg, 0.4 mg/mL, 7.0 mg/mL
, Oral, Solution, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Capsule, extended release, Capsule, extended release - Oral, Kit, Elixir, Elixir - Oral, Syrup, Syrup - Oral, Capsule - Oral, Capsule, Injection, Injection - Intravenous, Solution - Intravenous
Emphysema
, 8.0 mg/mL, 0.8 mg/mL, 1.6 mg/mL, 300.0 mg, 200.0 mg, 100.0 mg, 400.0 mg, 450.0 mg, 600.0 mg, 50.0 mg, 250.0 mg, 500.0 mg, 125.0 mg, 70.0 mg, 140.0 mg, 118.0 mg, 2.0 mg/mL, 4.0 mg/mL, 3.2 mg/mL, 175.0 mg, 65.0 mg, 75.0 mg, 350.0 mg, 130.0 mg, 0.4 mg/mL, 7.0 mg/mL
, Oral, Solution, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Capsule, extended release, Capsule, extended release - Oral, Kit, Elixir, Elixir - Oral, Syrup, Syrup - Oral, Capsule - Oral, Capsule, Injection, Injection - Intravenous, Solution - Intravenous
Bronchoconstriction
, 8.0 mg/mL, 0.8 mg/mL, 1.6 mg/mL, 300.0 mg, 200.0 mg, 100.0 mg, 400.0 mg, 450.0 mg, 600.0 mg, 50.0 mg, 250.0 mg, 500.0 mg, 125.0 mg, 70.0 mg, 140.0 mg, 118.0 mg, 2.0 mg/mL, 4.0 mg/mL, 3.2 mg/mL, 175.0 mg, 65.0 mg, 75.0 mg, 350.0 mg, 130.0 mg, 0.4 mg/mL, 7.0 mg/mL
, Oral, Solution, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Capsule, extended release, Capsule, extended release - Oral, Kit, Elixir, Elixir - Oral, Syrup, Syrup - Oral, Capsule - Oral, Capsule, Injection, Injection - Intravenous, Solution - Intravenous
Lung Diseases
, 8.0 mg/mL, 0.8 mg/mL, 1.6 mg/mL, 300.0 mg, 200.0 mg, 100.0 mg, 400.0 mg, 450.0 mg, 600.0 mg, 50.0 mg, 250.0 mg, 500.0 mg, 125.0 mg, 70.0 mg, 140.0 mg, 118.0 mg, 2.0 mg/mL, 4.0 mg/mL, 3.2 mg/mL, 175.0 mg, 65.0 mg, 75.0 mg, 350.0 mg, 130.0 mg, 0.4 mg/mL, 7.0 mg/mL
, Oral, Solution, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Capsule, extended release, Capsule, extended release - Oral, Kit, Elixir, Elixir - Oral, Syrup, Syrup - Oral, Capsule - Oral, Capsule, Injection, Injection - Intravenous, Solution - Intravenous
Bronchodilation
, 8.0 mg/mL, 0.8 mg/mL, 1.6 mg/mL, 300.0 mg, 200.0 mg, 100.0 mg, 400.0 mg, 450.0 mg, 600.0 mg, 50.0 mg, 250.0 mg, 500.0 mg, 125.0 mg, 70.0 mg, 140.0 mg, 118.0 mg, 2.0 mg/mL, 4.0 mg/mL, 3.2 mg/mL, 175.0 mg, 65.0 mg, 75.0 mg, 350.0 mg, 130.0 mg, 0.4 mg/mL, 7.0 mg/mL
, Oral, Solution, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Capsule, extended release, Capsule, extended release - Oral, Kit, Elixir, Elixir - Oral, Syrup, Syrup - Oral, Capsule - Oral, Capsule, Injection, Injection - Intravenous, Solution - Intravenous
Bronchitis, Chronic
, 8.0 mg/mL, 0.8 mg/mL, 1.6 mg/mL, 300.0 mg, 200.0 mg, 100.0 mg, 400.0 mg, 450.0 mg, 600.0 mg, 50.0 mg, 250.0 mg, 500.0 mg, 125.0 mg, 70.0 mg, 140.0 mg, 118.0 mg, 2.0 mg/mL, 4.0 mg/mL, 3.2 mg/mL, 175.0 mg, 65.0 mg, 75.0 mg, 350.0 mg, 130.0 mg, 0.4 mg/mL, 7.0 mg/mL
, Oral, Solution, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Capsule, extended release, Capsule, extended release - Oral, Kit, Elixir, Elixir - Oral, Syrup, Syrup - Oral, Capsule - Oral, Capsule, Injection, Injection - Intravenous, Solution - Intravenous

Warnings

There are 20 known major drug interactions with Theo-Dur.
Common Theo-Dur Drug Interactions
Drug Name
Risk Level
Description
Acenocoumarol
Major
The metabolism of Acenocoumarol can be decreased when combined with Theophylline.
Aminophylline
Major
The metabolism of Aminophylline can be decreased when combined with Theophylline.
Axitinib
Major
The metabolism of Axitinib can be decreased when combined with Theophylline.
Bendamustine
Major
The metabolism of Bendamustine can be decreased when combined with Theophylline.
Brigatinib
Major
The metabolism of Brigatinib can be decreased when combined with Theophylline.
Theo-Dur Toxicity & Overdose RiskOverdosing on the drug can cause seizures, abnormal heart rhythms, and digestive issues.
image of a doctor in a lab doing drug, clinical research

Theo-Dur Novel Uses: Which Conditions Have a Clinical Trial Featuring Theo-Dur?

280 active clinical trials are assessing the potential of Theo-Dur in providing Bronchodilation, ameliorating Chronic Bronchitis and managing Asthma.
Condition
Clinical Trials
Trial Phases
Asthma
88 Actively Recruiting
Phase 4, Early Phase 1, Phase 2, Not Applicable, Phase 1, Phase 3
Chronic Obstructive Pulmonary Disease
85 Actively Recruiting
Phase 3, Not Applicable, Phase 1, Phase 2, Early Phase 1, Phase 4
Airway secretion clearance therapy
0 Actively Recruiting
Bronchoconstriction
0 Actively Recruiting
Bronchodilation
0 Actively Recruiting
Emphysema
4 Actively Recruiting
Phase 2, Not Applicable
Bronchitis, Chronic
0 Actively Recruiting
Acute Bronchitis
1 Actively Recruiting
Not Applicable
Bronchitis, Chronic
0 Actively Recruiting
Lung Diseases
7 Actively Recruiting
Not Applicable, Phase 1, Phase 2
Bronchial Spasm
0 Actively Recruiting

Theo-Dur Reviews: What are patients saying about Theo-Dur?

5Patient Review
7/7/2010
Theo-Dur for Asthma
5Patient Review
6/3/2011
Theo-Dur for Asthma
I was feeling really bad, like I was going to have a stroke. But this treatment fixed me right up.
4.3Patient Review
6/12/2011
Theo-Dur for COPD with Chronic Bronchitis
I've been taking Theo-Dur for my asthma, bronchospasms, and bronchitis for over 40 years now, and it's always worked great for me.
4Patient Review
12/7/2008
Theo-Dur for Bronchi Muscle Spasm resulting from COPD
2.7Patient Review
2/24/2012
Theo-Dur for Asthma
I'm not sure if this medication contributed to my son's current health problems, but I've always wondered. We were desperate for something to help his asthma when he was younger and felt we had no choice. It did seem to help prevent wheezing at the time, but he's 30 now and has health problems and depression.
View All Reviews
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Patient Q&A Section about theo-dur

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is Theo-Dur used for?

"The xanthine class of drugs to which this medication belongs prevent wheezing and shortness of breath when used regularly. They work by relaxing the muscles around the airways so that they open up and the patient can breathe more easily. These drugs also decrease the lungs' response to irritants."

Answered by AI

Is Theo-Dur discontinued?

"is the last update for the drug class Methylxanthines. The Theo-Dur brand name has been discontinued and there are now generic equivalents available."

Answered by AI

Why is theophylline no longer used for asthma?

"Theophylline is a bronchodilator that is not as effective as inhaled bronchodilators because of the adverse effects that limit the dose."

Answered by AI

What is the generic name for Theo-Dur?

"This document contains information about side effects for theophylline. Some of the dosage forms listed on this page may not apply to the brand name Theo-Dur."

Answered by AI

Clinical Trials for Theo-Dur

Have you considered Theo-Dur clinical trials? We made a collection of clinical trials featuring Theo-Dur, we think they might fit your search criteria.
Have you considered Theo-Dur clinical trials? We made a collection of clinical trials featuring Theo-Dur, we think they might fit your search criteria.
Have you considered Theo-Dur clinical trials? We made a collection of clinical trials featuring Theo-Dur, we think they might fit your search criteria.
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