What is Theo-Dur
TheophyllineThe Generic name of this drug
Treatment SummaryTheophylline is a drug derived from tea that has multiple effects on the body including increasing urine production, relaxing smooth muscle, and stimulating the heart, lungs, and central nervous system. It works by blocking enzyme phosphodiesterase, adenosine receptors, and activating histone deacetylase. It is sold under several brand names such as Uniphyl and Theochron and is most commonly used for asthma, bronchospasm, and chronic obstructive pulmonary disease (COPD).
Elixophyllinis the brand name
Theo-Dur Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Elixophyllin
Theophylline
1979
114
Approved as Treatment by the FDA
Theophylline, commonly known as Elixophyllin, is approved by the FDA for 4 uses like Lung Disorder and Asthma .Lung Disorder
Asthma
Chronic Bronchitis
Bronchoconstriction
Effectiveness
How Theo-Dur Affects PatientsTheophylline, which is similar to caffeine and theobromine, is used to treat asthma and other airway problems. It helps by relaxing the airway muscles and reducing the body's response to irritants.
How Theo-Dur works in the bodyTheophylline is a medication that helps to open up the airways and reduce the responsiveness of the airways to various triggers. It does this by blocking an enzyme that breaks down a molecule in the cells that help keep the airways relaxed. It also binds to a receptor in the airways and prevents it from tightening. In inflammatory states, it helps reduce inflammation by stopping the transcription of certain genes.
When to interrupt dosage
The proposed dosage of Theo-Dur is contingent upon the indicated condition, including Bronchodilation, Bronchoconstriction and Chronic Obstructive Pulmonary Disease (COPD). The amount of dosage differs, in line with the method of administration set forth in the table below.Condition
Dosage
Administration
Bronchodilation
, 100.0 mg, 600.0 mg, 1.6 mg/mL, 4.0 mg/mL, 0.4 mg/mL, 8.0 mg/mL, 7.0 mg/mL, 0.8 mg/mL, 400.0 mg, 200.0 mg, 450.0 mg, 50.0 mg, 125.0 mg, 250.0 mg, 500.0 mg, 300.0 mg, 140.0 mg, 70.0 mg, 118.0 mg, 350.0 mg, 75.0 mg, 130.0 mg, 3.2 mg/mL, 2.0 mg/mL, 175.0 mg, 65.0 mg
, Injection, solution, Oral, Tablet, Syrup - Oral, Tablet - Oral, Liquid, Tablet, extended release, Capsule, extended release, Intravenous, Syrup, Elixir, Solution - Oral, Elixir - Oral, Tablet, extended release - Oral, Injection, solution - Intravenous, Capsule, extended release - Oral, Solution, Solution - Intravenous, Injection, Liquid - Oral, Injection - Intravenous, Kit, Capsule - Oral, Capsule
Bronchoconstriction
, 100.0 mg, 600.0 mg, 1.6 mg/mL, 4.0 mg/mL, 0.4 mg/mL, 8.0 mg/mL, 7.0 mg/mL, 0.8 mg/mL, 400.0 mg, 200.0 mg, 450.0 mg, 50.0 mg, 125.0 mg, 250.0 mg, 500.0 mg, 300.0 mg, 140.0 mg, 70.0 mg, 118.0 mg, 350.0 mg, 75.0 mg, 130.0 mg, 3.2 mg/mL, 2.0 mg/mL, 175.0 mg, 65.0 mg
, Injection, solution, Oral, Tablet, Syrup - Oral, Tablet - Oral, Liquid, Tablet, extended release, Capsule, extended release, Intravenous, Syrup, Elixir, Solution - Oral, Elixir - Oral, Tablet, extended release - Oral, Injection, solution - Intravenous, Capsule, extended release - Oral, Solution, Solution - Intravenous, Injection, Liquid - Oral, Injection - Intravenous, Kit, Capsule - Oral, Capsule
Chronic Obstructive Pulmonary Disease
, 100.0 mg, 600.0 mg, 1.6 mg/mL, 4.0 mg/mL, 0.4 mg/mL, 8.0 mg/mL, 7.0 mg/mL, 0.8 mg/mL, 400.0 mg, 200.0 mg, 450.0 mg, 50.0 mg, 125.0 mg, 250.0 mg, 500.0 mg, 300.0 mg, 140.0 mg, 70.0 mg, 118.0 mg, 350.0 mg, 75.0 mg, 130.0 mg, 3.2 mg/mL, 2.0 mg/mL, 175.0 mg, 65.0 mg
, Injection, solution, Oral, Tablet, Syrup - Oral, Tablet - Oral, Liquid, Tablet, extended release, Capsule, extended release, Intravenous, Syrup, Elixir, Solution - Oral, Elixir - Oral, Tablet, extended release - Oral, Injection, solution - Intravenous, Capsule, extended release - Oral, Solution, Solution - Intravenous, Injection, Liquid - Oral, Injection - Intravenous, Kit, Capsule - Oral, Capsule
Bronchospasm
, 100.0 mg, 600.0 mg, 1.6 mg/mL, 4.0 mg/mL, 0.4 mg/mL, 8.0 mg/mL, 7.0 mg/mL, 0.8 mg/mL, 400.0 mg, 200.0 mg, 450.0 mg, 50.0 mg, 125.0 mg, 250.0 mg, 500.0 mg, 300.0 mg, 140.0 mg, 70.0 mg, 118.0 mg, 350.0 mg, 75.0 mg, 130.0 mg, 3.2 mg/mL, 2.0 mg/mL, 175.0 mg, 65.0 mg
, Injection, solution, Oral, Tablet, Syrup - Oral, Tablet - Oral, Liquid, Tablet, extended release, Capsule, extended release, Intravenous, Syrup, Elixir, Solution - Oral, Elixir - Oral, Tablet, extended release - Oral, Injection, solution - Intravenous, Capsule, extended release - Oral, Solution, Solution - Intravenous, Injection, Liquid - Oral, Injection - Intravenous, Kit, Capsule - Oral, Capsule
Lung Disorder
, 100.0 mg, 600.0 mg, 1.6 mg/mL, 4.0 mg/mL, 0.4 mg/mL, 8.0 mg/mL, 7.0 mg/mL, 0.8 mg/mL, 400.0 mg, 200.0 mg, 450.0 mg, 50.0 mg, 125.0 mg, 250.0 mg, 500.0 mg, 300.0 mg, 140.0 mg, 70.0 mg, 118.0 mg, 350.0 mg, 75.0 mg, 130.0 mg, 3.2 mg/mL, 2.0 mg/mL, 175.0 mg, 65.0 mg
, Injection, solution, Oral, Tablet, Syrup - Oral, Tablet - Oral, Liquid, Tablet, extended release, Capsule, extended release, Intravenous, Syrup, Elixir, Solution - Oral, Elixir - Oral, Tablet, extended release - Oral, Injection, solution - Intravenous, Capsule, extended release - Oral, Solution, Solution - Intravenous, Injection, Liquid - Oral, Injection - Intravenous, Kit, Capsule - Oral, Capsule
Airway secretion clearance therapy
, 100.0 mg, 600.0 mg, 1.6 mg/mL, 4.0 mg/mL, 0.4 mg/mL, 8.0 mg/mL, 7.0 mg/mL, 0.8 mg/mL, 400.0 mg, 200.0 mg, 450.0 mg, 50.0 mg, 125.0 mg, 250.0 mg, 500.0 mg, 300.0 mg, 140.0 mg, 70.0 mg, 118.0 mg, 350.0 mg, 75.0 mg, 130.0 mg, 3.2 mg/mL, 2.0 mg/mL, 175.0 mg, 65.0 mg
, Injection, solution, Oral, Tablet, Syrup - Oral, Tablet - Oral, Liquid, Tablet, extended release, Capsule, extended release, Intravenous, Syrup, Elixir, Solution - Oral, Elixir - Oral, Tablet, extended release - Oral, Injection, solution - Intravenous, Capsule, extended release - Oral, Solution, Solution - Intravenous, Injection, Liquid - Oral, Injection - Intravenous, Kit, Capsule - Oral, Capsule
Chronic Bronchitis
, 100.0 mg, 600.0 mg, 1.6 mg/mL, 4.0 mg/mL, 0.4 mg/mL, 8.0 mg/mL, 7.0 mg/mL, 0.8 mg/mL, 400.0 mg, 200.0 mg, 450.0 mg, 50.0 mg, 125.0 mg, 250.0 mg, 500.0 mg, 300.0 mg, 140.0 mg, 70.0 mg, 118.0 mg, 350.0 mg, 75.0 mg, 130.0 mg, 3.2 mg/mL, 2.0 mg/mL, 175.0 mg, 65.0 mg
, Injection, solution, Oral, Tablet, Syrup - Oral, Tablet - Oral, Liquid, Tablet, extended release, Capsule, extended release, Intravenous, Syrup, Elixir, Solution - Oral, Elixir - Oral, Tablet, extended release - Oral, Injection, solution - Intravenous, Capsule, extended release - Oral, Solution, Solution - Intravenous, Injection, Liquid - Oral, Injection - Intravenous, Kit, Capsule - Oral, Capsule
Chronic bronchial inflammation
, 100.0 mg, 600.0 mg, 1.6 mg/mL, 4.0 mg/mL, 0.4 mg/mL, 8.0 mg/mL, 7.0 mg/mL, 0.8 mg/mL, 400.0 mg, 200.0 mg, 450.0 mg, 50.0 mg, 125.0 mg, 250.0 mg, 500.0 mg, 300.0 mg, 140.0 mg, 70.0 mg, 118.0 mg, 350.0 mg, 75.0 mg, 130.0 mg, 3.2 mg/mL, 2.0 mg/mL, 175.0 mg, 65.0 mg
, Injection, solution, Oral, Tablet, Syrup - Oral, Tablet - Oral, Liquid, Tablet, extended release, Capsule, extended release, Intravenous, Syrup, Elixir, Solution - Oral, Elixir - Oral, Tablet, extended release - Oral, Injection, solution - Intravenous, Capsule, extended release - Oral, Solution, Solution - Intravenous, Injection, Liquid - Oral, Injection - Intravenous, Kit, Capsule - Oral, Capsule
Acute Bronchitis
, 100.0 mg, 600.0 mg, 1.6 mg/mL, 4.0 mg/mL, 0.4 mg/mL, 8.0 mg/mL, 7.0 mg/mL, 0.8 mg/mL, 400.0 mg, 200.0 mg, 450.0 mg, 50.0 mg, 125.0 mg, 250.0 mg, 500.0 mg, 300.0 mg, 140.0 mg, 70.0 mg, 118.0 mg, 350.0 mg, 75.0 mg, 130.0 mg, 3.2 mg/mL, 2.0 mg/mL, 175.0 mg, 65.0 mg
, Injection, solution, Oral, Tablet, Syrup - Oral, Tablet - Oral, Liquid, Tablet, extended release, Capsule, extended release, Intravenous, Syrup, Elixir, Solution - Oral, Elixir - Oral, Tablet, extended release - Oral, Injection, solution - Intravenous, Capsule, extended release - Oral, Solution, Solution - Intravenous, Injection, Liquid - Oral, Injection - Intravenous, Kit, Capsule - Oral, Capsule
Emphysema
, 100.0 mg, 600.0 mg, 1.6 mg/mL, 4.0 mg/mL, 0.4 mg/mL, 8.0 mg/mL, 7.0 mg/mL, 0.8 mg/mL, 400.0 mg, 200.0 mg, 450.0 mg, 50.0 mg, 125.0 mg, 250.0 mg, 500.0 mg, 300.0 mg, 140.0 mg, 70.0 mg, 118.0 mg, 350.0 mg, 75.0 mg, 130.0 mg, 3.2 mg/mL, 2.0 mg/mL, 175.0 mg, 65.0 mg
, Injection, solution, Oral, Tablet, Syrup - Oral, Tablet - Oral, Liquid, Tablet, extended release, Capsule, extended release, Intravenous, Syrup, Elixir, Solution - Oral, Elixir - Oral, Tablet, extended release - Oral, Injection, solution - Intravenous, Capsule, extended release - Oral, Solution, Solution - Intravenous, Injection, Liquid - Oral, Injection - Intravenous, Kit, Capsule - Oral, Capsule
Asthma
, 100.0 mg, 600.0 mg, 1.6 mg/mL, 4.0 mg/mL, 0.4 mg/mL, 8.0 mg/mL, 7.0 mg/mL, 0.8 mg/mL, 400.0 mg, 200.0 mg, 450.0 mg, 50.0 mg, 125.0 mg, 250.0 mg, 500.0 mg, 300.0 mg, 140.0 mg, 70.0 mg, 118.0 mg, 350.0 mg, 75.0 mg, 130.0 mg, 3.2 mg/mL, 2.0 mg/mL, 175.0 mg, 65.0 mg
, Injection, solution, Oral, Tablet, Syrup - Oral, Tablet - Oral, Liquid, Tablet, extended release, Capsule, extended release, Intravenous, Syrup, Elixir, Solution - Oral, Elixir - Oral, Tablet, extended release - Oral, Injection, solution - Intravenous, Capsule, extended release - Oral, Solution, Solution - Intravenous, Injection, Liquid - Oral, Injection - Intravenous, Kit, Capsule - Oral, Capsule
Warnings
There are 20 known major drug interactions with Theo-Dur.Common Theo-Dur Drug Interactions
Drug Name
Risk Level
Description
Acenocoumarol
Major
The metabolism of Acenocoumarol can be decreased when combined with Theophylline.
Aminophylline
Major
The metabolism of Aminophylline can be decreased when combined with Theophylline.
Axitinib
Major
The metabolism of Axitinib can be decreased when combined with Theophylline.
Bendamustine
Major
The metabolism of Bendamustine can be decreased when combined with Theophylline.
Brigatinib
Major
The metabolism of Brigatinib can be decreased when combined with Theophylline.
Theo-Dur Toxicity & Overdose RiskOverdosing on the drug can cause seizures, abnormal heart rhythms, and digestive issues.
Theo-Dur Novel Uses: Which Conditions Have a Clinical Trial Featuring Theo-Dur?
280 active clinical trials are assessing the potential of Theo-Dur in providing Bronchodilation, ameliorating Chronic Bronchitis and managing Asthma.Condition
Clinical Trials
Trial Phases
Chronic Obstructive Pulmonary Disease
104 Actively Recruiting
Not Applicable, Early Phase 1, Phase 1, Phase 2, Phase 3, Phase 4
Bronchodilation
0 Actively Recruiting
Chronic Bronchitis
6 Actively Recruiting
Not Applicable, Phase 3, Phase 2, Phase 4
Asthma
152 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 4, Phase 3, Early Phase 1
Emphysema
13 Actively Recruiting
Phase 3, Phase 4, Early Phase 1, Phase 1, Phase 2, Not Applicable
Acute Bronchitis
11 Actively Recruiting
Not Applicable, Phase 3, Phase 2, Phase 4
Bronchospasm
0 Actively Recruiting
Chronic bronchial inflammation
0 Actively Recruiting
Bronchoconstriction
0 Actively Recruiting
Airway secretion clearance therapy
0 Actively Recruiting
Lung Disorder
8 Actively Recruiting
Not Applicable, Phase 1, Phase 2
Theo-Dur Reviews: What are patients saying about Theo-Dur?
5Patient Review
7/7/20105Patient Review
6/3/2011 I was feeling really bad, like I was going to have a stroke. But this treatment fixed me right up.
4.3Patient Review
6/12/2011 I've been taking Theo-Dur for my asthma, bronchospasms, and bronchitis for over 40 years now, and it's always worked great for me.
4Patient Review
12/7/20082.7Patient Review
2/24/2012 I'm not sure if this medication contributed to my son's current health problems, but I've always wondered. We were desperate for something to help his asthma when he was younger and felt we had no choice. It did seem to help prevent wheezing at the time, but he's 30 now and has health problems and depression.
2.3Patient Review
2/24/2011 This treatment is effective, but it seems to leave a terrible taste when eating food. Liquids are fine, but when I start to eat my tongue gets numb???
2Patient Review
12/2/20101.7Patient Review
5/29/2011 For years I was told this medicine was a steroid, and I took it for extended periods of time. As a result, I became overweight and have been struggling with my weight ever since. Additionally, I still had to go to the hospital several times for asthma issues.
Patient Q&A Section about theo-dur
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is Theo-Dur used for?
"The xanthine class of drugs to which this medication belongs prevent wheezing and shortness of breath when used regularly. They work by relaxing the muscles around the airways so that they open up and the patient can breathe more easily. These drugs also decrease the lungs' response to irritants."
Answered by AI
Is Theo-Dur discontinued?
"is the last update for the drug class Methylxanthines. The Theo-Dur brand name has been discontinued and there are now generic equivalents available."
Answered by AI
Why is theophylline no longer used for asthma?
"Theophylline is a bronchodilator that is not as effective as inhaled bronchodilators because of the adverse effects that limit the dose."
Answered by AI
What is the generic name for Theo-Dur?
"This document contains information about side effects for theophylline. Some of the dosage forms listed on this page may not apply to the brand name Theo-Dur."
Answered by AI