Tenoretic 50

Slow Heart Rate, Atrial Fibrillation, Migraine + 14 more
Treatment
6 FDA approvals
20 Active Studies for Tenoretic 50

What is Tenoretic 50

AtenololThe Generic name of this drug
Treatment SummaryAtenolol is a type of medication called a beta-blocker used to treat various heart conditions. It was developed in the 1960s and approved by the FDA in 1981. It is one of the most commonly prescribed beta-blockers, but it may not reduce the risk of death or cardiovascular disease in patients with hypertension. Atenolol may need to be used depending on the patient's age and other factors.
Tenorminis the brand name
image of different drug pills on a surface
Tenoretic 50 Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Tenormin
Atenolol
1990
432

Approved as Treatment by the FDA

Atenolol, otherwise called Tenormin, is approved by the FDA for 6 uses like Hemodynamically Stable and Slow Heart Rate .
Hemodynamically Stable
Slow Heart Rate
Heart Attack
Hypertensive disease
Used to treat Refractory Hypertension in combination with Chlorthalidone
Hypertensive disease
Helps manage High Blood Pressure (Hypertension)
Systolic Blood Pressure >100 mmHg

Effectiveness

How Tenoretic 50 Affects PatientsAtenolol is a drug that works mainly on the heart. It slows down the heart rate and makes it work less hard. This helps to reduce the mismatch between oxygen supply and demand, especially in people with narrowed coronary arteries. It also helps to prevent abnormal heart rhythms and can reduce the frequency of angina attacks. Atenolol can lower blood pressure, but not as much as other beta-blocker drugs. It is also thought to reduce peripheral vascular resistance. When taken, it may cause fatigue, depression, and sleep problems. It can also produce bronchoconstriction, which can interfere with asthma or COPD
How Tenoretic 50 works in the bodyAtenolol is a drug that works by blocking certain receptors in the heart and lungs. By blocking the beta-1 receptor, atenolol can increase heart rate and contractility while decreasing contraction time. This helps the heart pump blood more effectively. In the lungs, atenolol blocks a pathway that causes constriction, resulting in relaxation of the airways. This makes it easier to breathe. By targeting the specific receptors in the heart and lungs, atenolol can provide a therapeutic benefit without causing too many side effects.

When to interrupt dosage

The quantity of Tenoretic 50 is contingent upon the diagnosed disorder, including Atrial Fibrillation, Migraine and Hypertensive disease. The measure of dosage also relies upon the technique of delivery (e.g. Tablet - Oral or Tablet) described in the table underneath.
Condition
Dosage
Administration
Thyrotoxicosis
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous
Systolic Blood Pressure >100 mmHg
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous
Syndrome
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous
Migraine
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous
Tachycardia, Ventricular
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous
Tachycardia, Ventricular
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous
Coronary Artery Atherosclerosis
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous
Chest Pain
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous
prophylaxis of migraine headaches
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous
Hypertensive disease
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous
Heart Attack
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous
Hypertensive disease
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous
Secondary prevention Myocardial infarction
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous
Hemodynamically Stable
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous
Atrial Fibrillation
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous
Slow Heart Rate
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous
Congestive Heart Failure
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous

Warnings

Tenoretic 50 Contraindications
Condition
Risk Level
Notes
Heart Block
Do Not Combine
Shock, Cardiogenic
Do Not Combine
Sinus Bradycardia
Do Not Combine
overt cardiac failure
Do Not Combine
There are 20 known major drug interactions with Tenoretic 50.
Common Tenoretic 50 Drug Interactions
Drug Name
Risk Level
Description
4-Bromo-2,5-dimethoxyphenethylamine
Major
The therapeutic efficacy of 4-Bromo-2,5-dimethoxyphenethylamine can be decreased when used in combination with Atenolol.
4-Methoxyamphetamine
Major
The therapeutic efficacy of 4-Methoxyamphetamine can be decreased when used in combination with Atenolol.
Abediterol
Major
The therapeutic efficacy of Abediterol can be decreased when used in combination with Atenolol.
Adrafinil
Major
The therapeutic efficacy of Adrafinil can be decreased when used in combination with Atenolol.
Agrostis gigantea pollen
Major
The risk of a hypersensitivity reaction to Agrostis gigantea pollen is increased when it is combined with Atenolol.
Tenoretic 50 Toxicity & Overdose RiskThe toxic dose of Atenolol in mice is 2 g/kg when taken orally, 57 mg/kg when injected, 134 mg/kg when administered intraperitoneally, and 400 mg/kg when injected subcutaneously. In rats, the toxic dose is 2 g/kg when taken orally, 77 mg/kg when injected, and 600 mg/kg when injected subcutaneously. In rabbits, the toxic dose is 50 mg/kg when injected. Studies on rats and mice showed no evidence of cancer, even at doses 150 times the maximum recommended human dose. Mutagenic effects have not been observed in tests on
image of a doctor in a lab doing drug, clinical research

Tenoretic 50 Novel Uses: Which Conditions Have a Clinical Trial Featuring Tenoretic 50?

626 active research studies are currently assessing the utility of Tenoretic 50 in managing Atrial Fibrillation, Coronary Artery Atherosclerosis and Ventricular Tachycardia.
Condition
Clinical Trials
Trial Phases
prophylaxis of migraine headaches
0 Actively Recruiting
Migraine
52 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3, Phase 4, Early Phase 1
Secondary prevention Myocardial infarction
0 Actively Recruiting
Thyrotoxicosis
0 Actively Recruiting
Tachycardia, Ventricular
0 Actively Recruiting
Heart Attack
53 Actively Recruiting
Phase 4, Phase 2, Phase 3, Not Applicable, Phase 1, Early Phase 1
Atrial Fibrillation
146 Actively Recruiting
Not Applicable, Phase 2, Phase 4, Phase 1, Phase 3, Early Phase 1
Systolic Blood Pressure >100 mmHg
0 Actively Recruiting
Coronary Artery Atherosclerosis
2 Actively Recruiting
Not Applicable, Phase 4
Slow Heart Rate
7 Actively Recruiting
Phase 4, Not Applicable
Hemodynamically Stable
0 Actively Recruiting
Syndrome
3 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3
Hypertensive disease
0 Actively Recruiting
Congestive Heart Failure
312 Actively Recruiting
Phase 2, Phase 3, Not Applicable, Phase 1, Early Phase 1, Phase 4
Chest Pain
6 Actively Recruiting
Phase 2, Phase 3, Not Applicable, Phase 4
Tachycardia, Ventricular
0 Actively Recruiting
Hypertensive disease
19 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3

Tenoretic 50 Reviews: What are patients saying about Tenoretic 50?

5Patient Review
11/12/2008
Tenoretic 50 for High Blood Pressure
5Patient Review
9/20/2007
Tenoretic 50 for High Blood Pressure
4.3Patient Review
4/14/2011
Tenoretic 50 for High Blood Pressure
My blood pressure was lowered within a day of taking this medication, which I appreciate.
4.3Patient Review
12/6/2017
Tenoretic 50 for High Blood Pressure
I've been taking this medication for a couple of years now, and unfortunately I have started to experience hair loss.
3.3Patient Review
10/13/2009
Tenoretic 50 for High Blood Pressure
I've been taking Tenoretic for fifteen years and, in that time, it has kept my blood pressure at a normal level. Although, I do notice that it might go up if I'm experiencing stress or have eaten something salty. But, all things considered, this medication does its job well enough. Plus, my doctor monitors me closely to make sure there are no negative side-effects from long term use.
3Patient Review
9/2/2013
Tenoretic 50 for High Blood Pressure
This medication caused me to feel very dizzy.
3Patient Review
8/19/2009
Tenoretic 50 for High Blood Pressure
Everytime I take this medicine my blood pressure would drop to below 90. Also, I got a really bad sunburn from just mowing the lawn once. This is the first time that's happened to me. Later, I found out that this medication makes you very sensitive to bright light.
2.7Patient Review
8/14/2012
Tenoretic 50 for High Blood Pressure
I've been on this medication for nearly a decade, but it has yet to get my blood pressure below 140/80. If anything, in recent years it's gone up to above that mark. That said, I'm thankful that it at least keeps my blood pressure at a reasonable level - if it weren't for this drug, who knows where my BP would be?
2.7Patient Review
6/9/2008
Tenoretic 50 for High Blood Pressure
2Patient Review
9/15/2008
Tenoretic 50 for High Blood Pressure
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about tenoretic 50

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the generic name for tenoretic?

"The generic name for the medication is atenolol and chlorthalidone, and it is available in 50mg/25mg+ and 100mg/25mg dosages. The medication comes in tablet form and is scored for easy breaking."

Answered by AI

What is tenoretic used for?

"Atenolol is a beta-blocker that works by blocking the hormone epinephrine (adrenaline). This medication slows down your heart and decreases the amount of blood it pumps out. Chlorthalidone is a "water pill" (diuretic) that causes you to make more urine, which helps your body get rid of extra salt and water.

This medication is used to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. This product contains 2 medications: atenolol and chlorthalidone. Atenolol is a beta-blocker that works by blocking the hormone epinephrine (adrenaline). This medication slows down your heart and decreases the amount of blood it pumps out. Chlorthalidone is a "water pill" (diuretic) that causes you to make more urine, which helps your body get rid of extra salt and water."

Answered by AI

Is tenoretic the same as atenolol?

"This action then reduces the heart rate and blood pressure.

Tenoretic is a combination of two different medications: Atenolol is a selective beta blocker. It works by blocking specific (natural) compounds that may bind to receptors on the heart. By doing this, it reduces the heart rate and blood pressure."

Answered by AI

What drug class is tenoretic?

"Tenoretic is a prescription medication that is used to help manage the symptoms associated with high blood pressure. This medication can be used on its own or in conjunction with other medications. Tenoretic is part of a class of drugs known as Thiazide Combos."

Answered by AI

Clinical Trials for Tenoretic 50

Have you considered Tenoretic 50 clinical trials? We made a collection of clinical trials featuring Tenoretic 50, we think they might fit your search criteria.
Have you considered Tenoretic 50 clinical trials? We made a collection of clinical trials featuring Tenoretic 50, we think they might fit your search criteria.
Have you considered Tenoretic 50 clinical trials? We made a collection of clinical trials featuring Tenoretic 50, we think they might fit your search criteria.
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top