Temovate

Alopecia, Psoriasis, Severe Plaque psoriasis + 4 more
Treatment
18 Active Studies for Temovate

What is Temovate

Clobetasol propionateThe Generic name of this drug
Treatment SummaryClobetasol Propionate is a steroid-based medication used to reduce inflammation. It is more effective than similar drugs and was first described in 1974. It was approved by the FDA in 1985 for use in the United States.
Temovate Scalp Applicationis the brand name
image of different drug pills on a surface
Temovate Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Temovate Scalp Application
Clobetasol propionate
1990
245

Effectiveness

How Temovate Affects PatientsCorticosteroids work by blocking certain signals in the body that cause inflammation. Clobetasol propionate is usually used twice a day and can last for a long time. Corticosteroids can be taken in higher doses than the body naturally produces, so it has a wide safety range. However, patients should be aware that taking corticosteroids may reduce their body's ability to fight infections and suppress hormones.
How Temovate works in the bodyCorticosteroids help reduce inflammation by decreasing blood vessel expansion and preventing white blood cells from travelling to sites of inflammation. They also change the way certain genes are expressed, stopping some proteins from increasing inflammation and promoting proteins that reduce inflammation. Low doses of corticosteroids can reduce inflammation, while high doses weaken the immune system. When taken for an extended period, high doses of glucocorticoids bind to a different type of receptor, which increases sodium levels and decreases potassium levels.

When to interrupt dosage

The advised dose of Temovate is dependent upon the recognized condition, for example Psoriasis, corticosteroid responsive, Inflammatory Dermatosis and Pruritus. The amount of dosage fluctuates, as per the method of delivery (e.g. Topical or Ointment) showcased in the table beneath.
Condition
Dosage
Administration
Pruritus
0.4625 mg/mL, , 0.0005 mg/mg, 0.5 mg/mL, 50.0 mg/mL, 0.462 mg/mL, 0.0005 mL/mL, 0.00005 mg/mg, 0.05 %, 0.0005 mg/mL, 0.00025 mg/mg, 0.5 mg/mg, 0.00015 mg/mg
Topical, Solution, , Solution - Topical, Ointment, Cream, Ointment - Topical, Cream - Topical, Gel, Gel - Topical, Shampoo, Lotion, Lotion - Topical, Spray, Shampoo - Topical, Spray - Topical, Aerosol, foam, Aerosol, foam - Topical, Kit, Emulsion, Emulsion - Topical, Liquid, Liquid - Topical, Kit - Topical
Psoriasis
0.4625 mg/mL, , 0.0005 mg/mg, 0.5 mg/mL, 50.0 mg/mL, 0.462 mg/mL, 0.0005 mL/mL, 0.00005 mg/mg, 0.05 %, 0.0005 mg/mL, 0.00025 mg/mg, 0.5 mg/mg, 0.00015 mg/mg
Topical, Solution, , Solution - Topical, Ointment, Cream, Ointment - Topical, Cream - Topical, Gel, Gel - Topical, Shampoo, Lotion, Lotion - Topical, Spray, Shampoo - Topical, Spray - Topical, Aerosol, foam, Aerosol, foam - Topical, Kit, Emulsion, Emulsion - Topical, Liquid, Liquid - Topical, Kit - Topical
Alopecia
0.4625 mg/mL, , 0.0005 mg/mg, 0.5 mg/mL, 50.0 mg/mL, 0.462 mg/mL, 0.0005 mL/mL, 0.00005 mg/mg, 0.05 %, 0.0005 mg/mL, 0.00025 mg/mg, 0.5 mg/mg, 0.00015 mg/mg
Topical, Solution, , Solution - Topical, Ointment, Cream, Ointment - Topical, Cream - Topical, Gel, Gel - Topical, Shampoo, Lotion, Lotion - Topical, Spray, Shampoo - Topical, Spray - Topical, Aerosol, foam, Aerosol, foam - Topical, Kit, Emulsion, Emulsion - Topical, Liquid, Liquid - Topical, Kit - Topical
Psoriasis
0.4625 mg/mL, , 0.0005 mg/mg, 0.5 mg/mL, 50.0 mg/mL, 0.462 mg/mL, 0.0005 mL/mL, 0.00005 mg/mg, 0.05 %, 0.0005 mg/mL, 0.00025 mg/mg, 0.5 mg/mg, 0.00015 mg/mg
Topical, Solution, , Solution - Topical, Ointment, Cream, Ointment - Topical, Cream - Topical, Gel, Gel - Topical, Shampoo, Lotion, Lotion - Topical, Spray, Shampoo - Topical, Spray - Topical, Aerosol, foam, Aerosol, foam - Topical, Kit, Emulsion, Emulsion - Topical, Liquid, Liquid - Topical, Kit - Topical
Psoriasis
0.4625 mg/mL, , 0.0005 mg/mg, 0.5 mg/mL, 50.0 mg/mL, 0.462 mg/mL, 0.0005 mL/mL, 0.00005 mg/mg, 0.05 %, 0.0005 mg/mL, 0.00025 mg/mg, 0.5 mg/mg, 0.00015 mg/mg
Topical, Solution, , Solution - Topical, Ointment, Cream, Ointment - Topical, Cream - Topical, Gel, Gel - Topical, Shampoo, Lotion, Lotion - Topical, Spray, Shampoo - Topical, Spray - Topical, Aerosol, foam, Aerosol, foam - Topical, Kit, Emulsion, Emulsion - Topical, Liquid, Liquid - Topical, Kit - Topical
Severe Plaque psoriasis
0.4625 mg/mL, , 0.0005 mg/mg, 0.5 mg/mL, 50.0 mg/mL, 0.462 mg/mL, 0.0005 mL/mL, 0.00005 mg/mg, 0.05 %, 0.0005 mg/mL, 0.00025 mg/mg, 0.5 mg/mg, 0.00015 mg/mg
Topical, Solution, , Solution - Topical, Ointment, Cream, Ointment - Topical, Cream - Topical, Gel, Gel - Topical, Shampoo, Lotion, Lotion - Topical, Spray, Shampoo - Topical, Spray - Topical, Aerosol, foam, Aerosol, foam - Topical, Kit, Emulsion, Emulsion - Topical, Liquid, Liquid - Topical, Kit - Topical
corticosteroid responsive, Inflammatory Dermatosis
0.4625 mg/mL, , 0.0005 mg/mg, 0.5 mg/mL, 50.0 mg/mL, 0.462 mg/mL, 0.0005 mL/mL, 0.00005 mg/mg, 0.05 %, 0.0005 mg/mL, 0.00025 mg/mg, 0.5 mg/mg, 0.00015 mg/mg
Topical, Solution, , Solution - Topical, Ointment, Cream, Ointment - Topical, Cream - Topical, Gel, Gel - Topical, Shampoo, Lotion, Lotion - Topical, Spray, Shampoo - Topical, Spray - Topical, Aerosol, foam, Aerosol, foam - Topical, Kit, Emulsion, Emulsion - Topical, Liquid, Liquid - Topical, Kit - Topical

Warnings

There are 20 known major drug interactions with Temovate.
Common Temovate Drug Interactions
Drug Name
Risk Level
Description
2-Methoxyethanol
Major
The risk or severity of adverse effects can be increased when Clobetasol propionate is combined with 2-Methoxyethanol.
9-(N-methyl-L-isoleucine)-cyclosporin A
Major
The risk or severity of adverse effects can be increased when Clobetasol propionate is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Abatacept
Major
The risk or severity of adverse effects can be increased when Clobetasol propionate is combined with Abatacept.
Abemaciclib
Major
The metabolism of Abemaciclib can be increased when combined with Clobetasol propionate.
Abetimus
Major
The risk or severity of adverse effects can be increased when Clobetasol propionate is combined with Abetimus.
Temovate Toxicity & Overdose RiskTaking too much of a glucocorticoid such as clobetasol propionate can lead to the body not having enough of the steroid, as well as other problems. These include cataracts, glaucoma, high blood pressure, water retention, high cholesterol, stomach ulcers, pancreatitis, muscle problems, changes in emotions, skin thinning, allergies, acne, extra hair growth, weak immune system, diabetes, low calcium, low phosphate, and slowed growth. In case of an overdose, the dose may be adjusted or stopped and other treatments may be used to help manage symptoms.

Temovate Novel Uses: Which Conditions Have a Clinical Trial Featuring Temovate?

47 trials are currently assessing the potential of Temovate to treat corticosteroid-responsive Inflammatory Dermatosis, Psoriasis and Alopecia.
Condition
Clinical Trials
Trial Phases
Alopecia
16 Actively Recruiting
Early Phase 1, Not Applicable, Phase 3, Phase 2, Phase 1
Severe Plaque psoriasis
0 Actively Recruiting
Psoriasis
0 Actively Recruiting
Psoriasis
0 Actively Recruiting
corticosteroid responsive, Inflammatory Dermatosis
0 Actively Recruiting
Pruritus
0 Actively Recruiting
Psoriasis
0 Actively Recruiting

Temovate Reviews: What are patients saying about Temovate?

5Patient Review
10/8/2009
Temovate for Skin Inflammation
I found this treatment to be very effective in treating my Lichen Sclerosis. It burned a lot when I first applied it, but afterwards the itching and pain went away.
5Patient Review
7/15/2016
Temovate for Atopic Dermatitis
I've tried a lot of different things for my eczema, and this is by far the best.
5Patient Review
2/15/2008
Temovate for Skin Inflammation
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about temovate

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the generic for Temovate?

"Clobetasol is a much stronger (super-high-potency) corticosteroid than most others. Clobetasol can be found under the following different brand names: Temovate, Temovate E, Cormax, Clobex, Clobex Spray, Clarelux, Cormax Ointment, Cormax Scalp Application, Olux, Olux-E, and Olux-E Foam."

Answered by AI

What is Temovate used for?

"This medication is used to treat various skin conditions by reducing swelling, itching, and redness. It can be used to treat eczema, psoriasis, dermatitis, allergies, and rash."

Answered by AI

Can you buy Temovate over the counter?

"This medication is not available over the counter, you will need a prescription from your doctor to get it."

Answered by AI

Is Temovate cream a steroid?

"The drugs Temovate and Temovate E are both creams that contain steroids, and are used to treat conditions characterized by skin inflammation and itching."

Answered by AI

Clinical Trials for Temovate

Image of Advanced Dermatology & Cosmetic Surgery in Maitland, United States.

Xtresse Serum for Hair Loss

18 - 65
All Sexes
Maitland, FL
The goal of this study is to determine how safe and effective it is to improve hair growth by applying a serum daily on the scalp of men and women with thinning hair. The main aims of this trial are: 1. To confirm using photographic analysis, changes in the quality, volume, and thickness of hair. 2. To gauge patient satisfaction with hair changes and application process. 3. Monitor and report any adverse events associated with the daily usage of Xtressé serum. Participants who qualify will complete 4 visits after voluntary consent has been given. Participants will be given 4 bottles of serum to use during the study. The product will be applied daily over a 4-month period. Photographs and scalp analysis will be performed at each visit to measure changes in hair volume, thickness, and growth. Participants will complete a survey at the end of the study.
Waitlist Available
Has No Placebo
Advanced Dermatology & Cosmetic Surgery (+2 Sites)Melissa Rayner, MSRestore Biologics Holdings, Inc. dba Xtressé
Image of Advanced Dermatology & Cosmetic Surgery in Maitland, United States.

Xtressé Gummies for Alopecia

18 - 65
Female
Maitland, FL
The goal of this study is to determine how safe and effective it is to improve hair growth using an active gummy treatment in women with self-perceived thinning hair. The main aims of this trial are: 1. To confirm using photographic analysis, changes in the quality, volume, and thickness of hair. 2. To gauge patient satisfaction with hair changes and application process. 3. Monitor and report any adverse events associated with the daily intake of Xtressé Participants who qualify will complete 5 visits after voluntary consent has been given. Participants will be given a 30-day supply of the gummies at each visit over a 4-month period. Photographs and scalp analysis will be performed at each visit to measure changes in hair volume, thickness, and growth.
Waitlist Available
Has No Placebo
Advanced Dermatology & Cosmetic Surgery (+3 Sites)Melissa Y Rayner, MSRestore Biologics Holdings, Inc. dba Xtressé
Image of Advanced Dermatology & Cosmetic Surgery in Maitland, United States.

XVIE for Alopecia

28 - 65
Female
Maitland, FL
The goal of this study is to determine how safe and effective it is to improve hair growth using XVIE solution applied on the scalp of women with self-perceived thinning hair. The main aims of this trial are: 1. To confirm using photographic analysis, changes in the quality, volume, and thickness of hair. 2. To gauge patient satisfaction with hair changes and application process. Participants who qualify will complete 5 to 6 visits after voluntary consent has been given. Participant's scalp will be numbed and the XVIE solution will be applied by microneedling. Photographs will be taken at each visit to measure changes in hair volume, thickness, and growth. Every participant will receive active treatment twice over the 4 month period.
Waitlist Available
Has No Placebo
Advanced Dermatology & Cosmetic Surgery (+1 Sites)Melissa Y Rayner, MSRestore Biologics Holdings, Inc. dba Xtressé
Have you considered Temovate clinical trials? We made a collection of clinical trials featuring Temovate, we think they might fit your search criteria.Go to Trials
Image of Skin Wellness Dermatology in Birmingham, United States.

Xtressé Supplement and Serum for Alopecia

28 - 65
Female
Birmingham, AL
The goal of this clinical trial is to test how safe and effective it is to improve hair growth using an active gummy and serum combination treatment when compared to an inactive treatment combination in women with self-perceived thinning hair. The main questions this trial aims to answer are: * to confirm using photograph analytics, how much hair growth has increased in a marked area when using active treatment versus inactive treatment, and * participants assessment and satisfaction with the hair growth using scaled assessments. Participants who qualify will be asked to complete 6 to 7 visits after voluntarily consent has been given. The study is divided into two parts. In Part A participants will be randomly given either active or inactive treatment to use over 3 months. After 3 months, all participants will enter Part B of the study and will be given active treatment to use over the final 6 months of the study.
Recruiting
Paid Trial
Skin Wellness Dermatology (+1 Sites)Danielle LeavittRestore Biologics Holdings, Inc. dba Xtressé
Image of Marc Avram MD in New York, United States.

TargetCool + Benev Exosomes for Alopecia

18 - 70
All Sexes
New York, NY
This clinical trial is testing a new approach to help improve hair thinning using a combination of cosmetic treatments. The purpose of the study is to learn whether applying exosomes to the scalp, along with microneedling and a precision cooling device called TargetCool™. This study aims to determine whether this combination approach offers synergistic benefits for individuals with hair thinning. Exosomes are tiny particles that come from stem cells and contain growth factors and other nutrients. They are being studied for their potential to help regenerate skin and hair. TargetCool™ is an FDA-cleared device that uses precision cooling to reduce inflammation and improve comfort. Microneedling is a common, minimally invasive procedure that uses small needles to stimulate the skin and help absorb topical products more effectively. The study will include healthy men (ages 18 to 70) and women (ages approximately 45 to 70) who are not of childbearing potential. A total of 9 to 15 participants will be randomly placed into one of three groups: Group 1: Exosomes with TargetCool™ Group 2: Microneedling followed by exosomes and TargetCool™ Group 3: Microneedling followed by exosomes only Participants will receive four treatments over 9 weeks. Each visit may include microneedling, TargetCool™ treatment, and exosome application depending on group assignment. A small tattoo will be placed on the scalp to help capture consistent photographs, and a special imaging system (Canfield HairMetrix®) will be used to measure hair changes. Participants will return for follow-up visits at 3 and 6 months after the final treatment. The results will help determine whether this combination of cosmetic treatments is safe and beneficial for people experiencing hair thinning.
Waitlist Available
Has No Placebo
Marc Avram MDDawn Queen, MDRecens Medical, Inc.
Have you considered Temovate clinical trials? We made a collection of clinical trials featuring Temovate, we think they might fit your search criteria.Go to Trials
Have you considered Temovate clinical trials? We made a collection of clinical trials featuring Temovate, we think they might fit your search criteria.Go to Trials
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Terms of Service·Privacy Policy·Cookies·Security