Ssd
Septicemia, Wound Infection, Alopecia + 1 more
Treatment
2 FDA approvals
2 Active Studies for Ssd
Treatment for
Septicemia
What is Ssd
Silver sulfadiazine
The Generic name of this drug
Treatment Summary
Silver sulfadiazine is a topical antibiotic used mainly to treat second and third-degree burns. It belongs to a group of drugs called sulfa derivatives.
Silvadene
is the brand name
Ssd Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Silvadene
Silver sulfadiazine
1973
69
Approved as Treatment by the FDA
Silver sulfadiazine, also known as Silvadene, is approved by the FDA for 2 uses which include Wound Infections and Wound Infection .
Wound Infections
Used to treat Wound Infections in combination with Chlorhexidine
Wound Infection
Used to treat Wound Infections in combination with Chlorhexidine
Effectiveness
How Ssd Affects Patients
Silver sulfadiazine is a powerful antibiotic that is effective against many types of bacteria and yeast. It does not interfere with carbonic anhydrase, which makes it a good choice if other drugs in this category are not suitable.
How Ssd works in the body
Silver sulfadiazine works differently from silver nitrate and sodium sulfadiazine. It attacks bacteria directly on the cell membrane and cell wall, causing cell death. Silver ions bind to proteins in the cells, disrupting their normal functions. Sulfadiazine stops bacteria from making the enzyme dihydropteroate synthetase, which is needed to make folic acid. Together, these two processes create a powerful antibacterial agent.
When to interrupt dosage
The advocated dosage of Ssd is contingent upon the determined disorder, for example Septicemia, Second Degree Burns and Third Degree Burns. The amount of dosage relies upon the technique of delivery specified in the table beneath.
Condition
Dosage
Administration
Wound Infection
0.01 mg/mg, , 1.0 %, 1.0 mg/mg
, Cream, Topical, Cream - Topical, Gel, Gel - Topical
Burns
0.01 mg/mg, , 1.0 %, 1.0 mg/mg
, Cream, Topical, Cream - Topical, Gel, Gel - Topical
Septicemia
0.01 mg/mg, , 1.0 %, 1.0 mg/mg
, Cream, Topical, Cream - Topical, Gel, Gel - Topical
Alopecia
0.01 mg/mg, , 1.0 %, 1.0 mg/mg
, Cream, Topical, Cream - Topical, Gel, Gel - Topical
Warnings
Ssd has three contraindications and should not be ingested along with the conditions described in the subsequent table.
Ssd Contraindications
Condition
Risk Level
Notes
Prematurity
Do Not Combine
Kernicterus
Do Not Combine
newborn infants during the first 2 months of life
Do Not Combine
There are 17 known major drug interactions with Ssd.
Common Ssd Drug Interactions
Drug Name
Risk Level
Description
Allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen
Major
The therapeutic efficacy of Allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen can be decreased when used in combination with Silver sulfadiazine.
Benzylpenicillin
Moderate
Silver sulfadiazine may decrease the excretion rate of Benzylpenicillin which could result in a higher serum level.
Estetrol
Moderate
The therapeutic efficacy of Estetrol can be decreased when used in combination with Silver sulfadiazine.
Insulin argine
Moderate
The risk or severity of hypoglycemia can be increased when Silver sulfadiazine is combined with Insulin argine.
Insulin aspart
Moderate
The risk or severity of hypoglycemia can be increased when Silver sulfadiazine is combined with Insulin aspart.
Ssd Toxicity & Overdose Risk
The lowest toxic dose of this drug in rats has been found to be 10001mg/kg.
Ssd Novel Uses: Which Conditions Have a Clinical Trial Featuring Ssd?
Two active clinical trials are currently being conducted to evaluate the potential of Ssd to provide relief from Third Degree Burns, Second Degree Burns and Wound Infections.
Condition
Clinical Trials
Trial Phases
Septicemia
0 Actively Recruiting
Alopecia
0 Actively Recruiting
Wound Infection
0 Actively Recruiting
Burns
2 Actively Recruiting
Phase 2
Ssd Reviews: What are patients saying about Ssd?
4.7
Patient Review
4/18/2017
Ssd for Skin Ulcer
Patient Q&A Section about ssd
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
What's the difference between SSD and hard drive?
"An SSD has the same function as a hard drive, but instead of storing data on a spinning disk, it stores it on interconnected flash-memory chips that can retain the data even when there is no power."
Answered by AI
Is SSD a RAM?
"While they appear to be made with memory chips, they are not actually RAM. SSDs use a different type of memory and cannot be accessed directly by your computer's processor. They are much slower than RAM, but can still make a significant difference in your computer's performance."
Answered by AI
What's better SSD or HDD?
"Solid state drives are typically faster, more durable, more compact, quieter, and consume less energy than their HDD counterparts. HDDs are typically more affordable and may offer easier data recovery in the event of damage. However, SSDs usually offer superior performance overall - especially since modern SSDs are just as reliable as HDDs."
Answered by AI
Whats is SSD?
"A solid-state drive is a storage device used in computers that stores data on solid-state flash memory. This type of drive is used as a replacement for a traditional hard disk drive and performs the same basic functions."
Answered by AI