Ssd

Septicemia, Wound Infection, Alopecia + 1 more

Treatment

2 FDA approvals

3 Active Studies for Ssd

Treatment for

Septicemia

What is Ssd

Silver sulfadiazineThe Generic name of this drug

Treatment SummarySilver sulfadiazine is a topical antibiotic used mainly to treat second and third-degree burns. It belongs to a group of drugs called sulfa derivatives.

Silvadeneis the brand name

image of different drug pills on a surface

Ssd Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Silvadene

Silver sulfadiazine

1973

Approved as Treatment by the FDA

Silver sulfadiazine, also known as Silvadene, is approved by the FDA for 2 uses which include Wound Infections and Wound Infection .

Wound Infections

Used to treat Wound Infections in combination with Chlorhexidine

Wound Infection

Used to treat Wound Infections in combination with Chlorhexidine

Effectiveness

How Ssd Affects PatientsSilver sulfadiazine is a powerful antibiotic that is effective against many types of bacteria and yeast. It does not interfere with carbonic anhydrase, which makes it a good choice if other drugs in this category are not suitable.

How Ssd works in the bodySilver sulfadiazine works differently from silver nitrate and sodium sulfadiazine. It attacks bacteria directly on the cell membrane and cell wall, causing cell death. Silver ions bind to proteins in the cells, disrupting their normal functions. Sulfadiazine stops bacteria from making the enzyme dihydropteroate synthetase, which is needed to make folic acid. Together, these two processes create a powerful antibacterial agent.

When to interrupt dosage

The advocated dosage of Ssd is contingent upon the determined disorder, for example Septicemia, Second Degree Burns and Third Degree Burns. The amount of dosage relies upon the technique of delivery specified in the table beneath.

Condition

Dosage

Administration

Septicemia

0.01 mg/mg, , 1.0 %, 1.0 mg/mg

, Topical, Cream, Cream - Topical, Gel - Topical, Gel

Wound Infection

0.01 mg/mg, , 1.0 %, 1.0 mg/mg

, Topical, Cream, Cream - Topical, Gel - Topical, Gel

Alopecia

0.01 mg/mg, , 1.0 %, 1.0 mg/mg

, Topical, Cream, Cream - Topical, Gel - Topical, Gel

Burns

0.01 mg/mg, , 1.0 %, 1.0 mg/mg

, Topical, Cream, Cream - Topical, Gel - Topical, Gel

Warnings

Ssd has three contraindications and should not be ingested along with the conditions described in the subsequent table.Ssd Contraindications

Condition

Risk Level

Notes

Prematurity

Do Not Combine

Kernicterus

Do Not Combine

newborn infants during the first 2 months of life

Do Not Combine

There are 17 known major drug interactions with Ssd.

Common Ssd Drug Interactions

Drug Name

Risk Level

Description

Allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen

Major

The therapeutic efficacy of Allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen can be decreased when used in combination with Silver sulfadiazine.

Benzylpenicillin

Moderate

Silver sulfadiazine may decrease the excretion rate of Benzylpenicillin which could result in a higher serum level.

Estetrol

Moderate

The therapeutic efficacy of Estetrol can be decreased when used in combination with Silver sulfadiazine.

Insulin argine

Moderate

The risk or severity of hypoglycemia can be increased when Silver sulfadiazine is combined with Insulin argine.

Insulin aspart

Moderate

The risk or severity of hypoglycemia can be increased when Silver sulfadiazine is combined with Insulin aspart.

Ssd Toxicity & Overdose RiskThe lowest toxic dose of this drug in rats has been found to be 10001mg/kg.

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Ssd Novel Uses: Which Conditions Have a Clinical Trial Featuring Ssd?

Two active clinical trials are currently being conducted to evaluate the potential of Ssd to provide relief from Third Degree Burns, Second Degree Burns and Wound Infections.

Condition

Clinical Trials

Trial Phases

Septicemia

0 Actively Recruiting

Alopecia

0 Actively Recruiting

Wound Infection

0 Actively Recruiting

Burns

3 Actively Recruiting

Phase 2, Phase 3

Ssd Reviews: What are patients saying about Ssd?

4.7Patient Review

4/18/2017

Ssd for Skin Ulcer

After years of dealing with an ever-growing ulcer on my leg, this treatment finally started to show some progress. In just three weeks of using it once per day, I've seen approximately 40-50% new skin growth. If it weren't for the prescription, I would use this more often!

image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about ssd

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What's the difference between SSD and hard drive?

"An SSD has the same function as a hard drive, but instead of storing data on a spinning disk, it stores it on interconnected flash-memory chips that can retain the data even when there is no power."

Answered by AI

Is SSD a RAM?

"While they appear to be made with memory chips, they are not actually RAM. SSDs use a different type of memory and cannot be accessed directly by your computer's processor. They are much slower than RAM, but can still make a significant difference in your computer's performance."

Answered by AI

What's better SSD or HDD?

"Solid state drives are typically faster, more durable, more compact, quieter, and consume less energy than their HDD counterparts. HDDs are typically more affordable and may offer easier data recovery in the event of damage. However, SSDs usually offer superior performance overall - especially since modern SSDs are just as reliable as HDDs."

Answered by AI

Whats is SSD?

"A solid-state drive is a storage device used in computers that stores data on solid-state flash memory. This type of drive is used as a replacement for a traditional hard disk drive and performs the same basic functions."

Answered by AI