Nudges for MRI Screening in Women with Dense Breasts

Recruiting at 1 trial location

Overseen By Claudia Fernandez Perez, MHS

Age: 18+

Sex: Female

Trial Phase: Academic

Sponsor: Abramson Cancer Center at Penn Medicine

Disqualifiers: Breast cancer history, Recent ultrasound, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: Unknown

1358 Participants Needed

Trial Summary

What is the purpose of this trial?

This trial aims to see if sending reminders can increase the use of MRI scans among women with extremely dense breasts. These women are at higher risk for breast cancer, and MRIs can detect tumors that regular mammograms might miss. The study hopes these reminders will lead to better cancer detection.

Research Team

Anne Marie McCarthy, PhD

Principal Investigator

University of Pennsylvania

Eligibility Criteria

This trial is for women aged 40-74 with extremely dense breasts who had a non-actionable mammogram within the last 6 months at specified Penn Medicine locations. They must have a valid mobile number, and their provider should have ordered the initial mammogram. Women with prior breast cancer or recent MRI/ultrasound are excluded.

Inclusion Criteria

I have a working mobile phone number.

My doctor has ordered my first mammogram.

You had a mammogram within the last 6 months that didn't show any concerning issues.

Exclusion Criteria

You have not had a breast MRI in the last 2 years.

You have not had an ultrasound recently or at the same time as the study.

I have had breast cancer before.

Timeline

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Intervention

Participants receive nudges through EHR and/or text messaging to increase MRI utilization

6 months

Follow-up

Participants are monitored for MRI ordering, scheduling, and completion, as well as false-positive and cancer detection rates

6 months

Treatment Details

Interventions

• Patient nudge
• Provider nudge

Trial Overview The study tests if 'nudges' to either patients, providers, or both can increase breast MRI screenings among women with very dense breasts. It also examines if there's a difference in response between Black and White women.

Participant Groups

Group I: Provider nudge only Experimental Treatment 1 Intervention

Nudge sent to provider through EHR.

Group II: Patient nudge only Experimental Treatment 1 Intervention

Nudge sent to the patient through text messaging.

Group III: Patient and provider nudge Experimental Treatment 2 Interventions

Nudge sent to both provider through EHR, and to patient through text messaging.

Group IV: Usual care (no nudge) Active Control 1 Intervention

Usual standard of care, no nudging.

Who Is Running the Clinical Trial?

Abramson Cancer Center at Penn Medicine

Lead Sponsor

Trials

425

Recruited

464,000+

University of Pennsylvania

Lead Sponsor

Trials

2,118

Recruited

45,270,000+

National Cancer Institute (NCI)

Collaborator

Trials

14,080

Recruited

41,180,000+