Sorilux

Psoriasis, Psoriasis Vulgaris

Treatment

20 Active Studies for Sorilux

Treatment for

Psoriasis

What is Sorilux

CalcipotriolThe Generic name of this drug

Treatment SummaryCalcipotriol is a medication derived from Vitamin D. It is used to treat skin disorders such as psoriasis and eczema.

Calcipotrieneis the brand name

image of different drug pills on a surface

Sorilux Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Calcipotriene

Calcipotriol

1996

Effectiveness

How Sorilux Affects PatientsCalcipotriene is an artificial form of vitamin D. Vitamin D is produced when the skin is exposed to sunshine, which turns the skin's 7-dehydrocholesterol into vitamin D3 (also known as cholecalciferol).

How Sorilux works in the bodyWe don't know exactly how calcipotriol works to treat psoriasis, but it appears to have a similar effect on the body's cells as Vitamin D does. The Vitamin D receptor, which is found on cells in many different parts of the body, binds to calcipotriol. This binding then changes the way certain genes are expressed, which in turn affects how cells differentiate and reproduce.

When to interrupt dosage

The endorsed dosage of Sorilux depends on the diagnosed condition. The measure of dosage is contingent upon the method of administration stated in the table beneath.

Condition

Dosage

Administration

Psoriasis

, 0.05 mg/mL, 0.00005 mg/mg

, Topical, Solution, Solution - Topical, Cream, Cream - Topical, Ointment, Ointment - Topical, Spray, metered, Spray, metered - Topical, Suspension, Suspension - Topical, Gel - Topical, Gel, Aerosol, foam, Aerosol, foam - Topical, Kit, Kit - Topical

Psoriasis Vulgaris

, 0.05 mg/mL, 0.00005 mg/mg

Warnings

Sorilux has three contraindications and should not be administered in combination with any of the conditions specified in the following table.Sorilux Contraindications

Condition

Risk Level

Notes

Hypercalcemia

Do Not Combine

vitamin D intoxication

Do Not Combine

Facial Paralysis

Do Not Combine

There are 15 known major drug interactions with Sorilux.

Common Sorilux Drug Interactions

Drug Name

Risk Level

Description

Calcium

Moderate

The risk or severity of adverse effects can be increased when Calcipotriol is combined with Calcium.

Calcium Phosphate

Moderate

The risk or severity of adverse effects can be increased when Calcipotriol is combined with Calcium Phosphate.

Calcium acetate

Moderate

The risk or severity of adverse effects can be increased when Calcipotriol is combined with Calcium acetate.

Calcium carbonate

Moderate

The risk or severity of adverse effects can be increased when Calcipotriol is combined with Calcium carbonate.

Calcium cation

Moderate

The risk or severity of adverse effects can be increased when Calcipotriol is combined with Calcium cation.

Sorilux Toxicity & Overdose RiskWhen applied directly to the skin, calcipotriene can be absorbed into the bloodstream and cause an increase in calcium levels in the blood. Using too much of this drug can lead to an overdose.

image of a doctor in a lab doing drug, clinical research

Sorilux Novel Uses: Which Conditions Have a Clinical Trial Featuring Sorilux?

18 active clinical trials are presently evaluating the effectiveness of Sorilux in managing Plaque Psoriasis.

Condition

Clinical Trials

Trial Phases

Psoriasis

0 Actively Recruiting

Psoriasis Vulgaris

25 Actively Recruiting

Early Phase 1, Phase 3, Not Applicable, Phase 4, Phase 2

Sorilux Reviews: What are patients saying about Sorilux?

4.3Patient Review

10/18/2020

Sorilux for Plaque Psoriasis

I'm getting extreme sun sensitivity and increased sensitivity to other products while using this foam. The foam also does not absorb well into my scalp through my thick hair.

1.7Patient Review

4/13/2021

Sorilux for Psoriasis of Scalp

Applying this to my scalp was really tough and I had to go back to using a different medicine. It's hard for me to give a good survey of it because of how difficult it was to use.

1.3Patient Review

12/26/2013

Sorilux for Psoriasis of Scalp

Unfortunately, this caused an extreme red rash where I applied it.

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Patient Q&A Section about sorilux

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Sorilux a steroid?

"SORILUX Foam is not a steroid. It is a vitamin D3 analog that helps the skin to better absorb calcium."

Answered by AI

What is Sorilux used for?

"This medication is used to treat psoriasis by slowing the growth of skin cells with calcipotriene, a form of vitamin d."

Answered by AI

Can you put Sorilux on your face?

"This medication is only meant to be used on the skin- do not get it on your face or in any other bodily cavity. If you are pregnant or planning on becoming pregnant, inform your doctor."

Answered by AI

How much does Sorilux cost?

"The average cost of Sorilux topical foam 0.005%, depending on the pharmacy, is around $943 for 60 grams. This price is for cash customers only and does not account for insurance plans."

Answered by AI