Sodium Sulfate
Bowel preparation therapy
Treatment
1 FDA approval
1 Active Study for Sodium Sulfate
Treatment for
Bowel preparation therapy
What is Sodium Sulfate
Sodium sulfate
The Generic name of this drug
Treatment Summary
Sodium Sulfate Anhydrous is a form of sulfuric acid that breaks apart into sodium and sulfate ions when mixed with water. Sodium ions are important for maintaining electrolyte balance in the body, and Sodium Sulfate Anhydrous is used to replenish electrolytes in the body and make sure that the body's fluid and electrolyte levels don't get too imbalanced. It is used in balanced solutions so that it won't cause the body to absorb or excrete water or ions.
GoLYTELY
is the brand name
Sodium Sulfate Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
GoLYTELY
Sodium sulfate
1984
34
Approved as Treatment by the FDA
Sodium sulfate, also known as GoLYTELY, is approved by the FDA for 1 uses such as Bowel preparation therapy .
Bowel preparation therapy
Effectiveness
How Sodium Sulfate Affects Patients
Causes watery diarrhea by drawing water into the intestines due to the unabsorbed sulfate salts and polyethylene glycol (PEG) in the digestive tract. The sulfate salts provide sulfate anions, which do not get absorbed into the body, and PEG which is also not absorbed, draws water into the intestines.
How Sodium Sulfate works in the body
MoviPrep empties the colon by causing an increase in watery stools. This is due to the osmotic activity of its ingredients, which include polyethylene glycol 3350, sodium sulfate, sodium chloride, potassium chloride, sodium ascorbate, and ascorbic acid. When taken with one liter of additional clear liquid, the ingredients do not absorb or release any ions or water.
When to interrupt dosage
The prescribed dosage of Sodium Sulfate is conditional upon the specified condition. The exact measure of dosage is contingent upon the delivery approach (e.g. Powder, for solution or Oral) noted in the table underneath.
Condition
Dosage
Administration
Bowel preparation therapy
22.74 mg/mL, , 0.2274 mg/mg, 0.2272 mg/mg, 17500.0 mg/mL, 21.5 mg/mL, 0.02 mg/mg, 8.0 mg, 22740.0 mg, 5740.0 mg, 22960.0 mg, 1420.0 mg, 5680.0 mg, 22.72 mg/mL, 285.0 mg, 1.75 mg/mg, 7.5 mg/mL, 9000.0 mg, 7500.0 mg, 175.0 mg/mL, 131.3 mg/mL, 17750.0 mg, 105.6 mg/mL, 0.0812 mg/mg, 5.74 mg/mL, 0.12 mmol/mL, 5.68 mg/mL, 0.227 mg/mg, 0.2296 mg/mg
Powder, for solution - Oral, , Oral, Powder, for solution, Solution, concentrate, Solution, concentrate - Oral, Powder, for solution - Nasogastric; Oral, Nasogastric; Oral, Powder - Oral; Topical, Oral; Topical, Powder, Capsule - Oral, Capsule, Kit; Powder, for solution; Tablet, delayed release, Kit; Powder, for solution; Tablet, delayed release - Oral, Liquid - Oral, Liquid, Powder - Oral, Solution - Oral, Solution, Nasogastric, Powder, for solution - Nasogastric, Tablet, effervescent - Oral, Tablet, effervescent, Kit, Kit - Oral, Tablet, Tablet - Oral
Warnings
There are 20 known major drug interactions with Sodium Sulfate.
Common Sodium Sulfate Drug Interactions
Drug Name
Risk Level
Description
Acrivastine
Minor
Sodium sulfate may decrease the excretion rate of Acrivastine which could result in a higher serum level.
Albutrepenonacog alfa
Minor
Sodium sulfate may decrease the excretion rate of Albutrepenonacog alfa which could result in a higher serum level.
Alloin
Minor
The risk or severity of adverse effects can be increased when Sodium sulfate is combined with Alloin.
Almasilate
Minor
Sodium sulfate may decrease the excretion rate of Almasilate which could result in a higher serum level.
Antithrombin III human
Minor
Sodium sulfate may decrease the excretion rate of Antithrombin III human which could result in a higher serum level.
Sodium Sulfate Toxicity & Overdose Risk
The toxic dose of this drug for mice is 5989mg/kg when taken orally, and 1220mg/kg when given intravenously. Rabbits experience a toxic dose of 1220mg/kg when given intravenously.
Sodium Sulfate Novel Uses: Which Conditions Have a Clinical Trial Featuring Sodium Sulfate?
An active clinical trial is assessing the potential of Sodium Sulfate to be used as an agent in Bowel preparation therapy.
Condition
Clinical Trials
Trial Phases
Bowel preparation therapy
1 Actively Recruiting
Phase 1, Phase 2
Patient Q&A Section about sodium sulfate
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Is sodium sulfate toxic?
"The toxicity of sodium sulfate has not been reliably established, but it is probably much higher than 5000 mg/kg. In a study of inhalation, no adverse effects were found at 10 mg/m3. Also, human data indicate a very low acute toxicity of sodium sulfate."
Answered by AI
What does sodium sulfate do to water?
"Sodium sulfate anhydrous is a salt form of sulfuric acid where the sodium and sulfate ions are not hydrated. In water, it breaks down into sodium and sulfate ions. Sodium ions are the main cation, or positively charged ion, in extracellular fluid and play an important role in treating fluid and electrolyte disorders."
Answered by AI
What is sodium sulfate in food?
"It is also used as a reducing agent in photographic developing.
Sodium sulfite is a white powder that is soluble in water and has a salty, sulfurous taste. It is primarily used as a food preservative and as an antioxidant. It is also used as a reducing agent in photographic developing."
Answered by AI
What is the sodium sulfate used for?
"Sodium sulphate is used to dry organic liquids and as a filler in powdered home laundry detergents. It can also be used as a fining agent to remove small air bubbles from molten glass. The decahydrate form of Glauber's salt was historically used as a laxative to remove certain drugs from the body."
Answered by AI