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What is Quasense
LevonorgestrelThe Generic name of this drug
Treatment SummaryLevonorgestrel (LNG) is a type of synthetic hormone used in contraception and hormone therapy. It is also known as ‘Plan B’ and is used as an emergency contraceptive pill or as a hormone released from an intrauterine device (IUD). Other long-term devices containing levonorgestrel are also available, such as Jaydess, Kyleena and Mirena. Levonorgestrel is the most widely used emergency contraceptive pill and was approved by the FDA in 1982. It is highly effective and has fewer side effects than other emergency contraceptives due to its lack of estrogen.
Triphasil-21is the brand name
Quasense Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Triphasil-21
Levonorgestrel
1984
243
Approved as Treatment by the FDA
Levonorgestrel, also known as Triphasil-21, is approved by the FDA for 6 uses including moderate Menopausal Vasomotor Symptoms and Emergency Contraception .moderate Menopausal Vasomotor Symptoms
Used to treat moderate Menopausal Vasomotor Symptoms in combination with Estradiol
Emergency Contraception
Has had at least 1 child
Postmenopausal Osteoporosis
Used to treat Postmenopausal Osteoporosis in combination with Estradiol
Menopause
Used to treat severe Vasomotor Symptoms Associated With Menopause in combination with Estradiol
Hot flashes
Used to treat Menopause in combination with Estradiol
Effectiveness
How Quasense Affects PatientsLevonorgestrel is a form of contraception that prevents pregnancy by blocking ovulation, fertilization, and implantation. If taken in the form of an emergency contraceptive pill within 72 hours after intercourse, it is 89% effective. When used as an intrauterine or implantable device, it is over 99% effective. Additionally, it can be used as a form of hormone therapy to help prevent cancer in the uterus.
How Quasense works in the bodyLevonorgestrel is a hormone used in contraceptives and hormone therapy. To prevent ovulation, it binds to progesterone and androgen receptors and slows the release of a hormone from the brain that triggers ovulation. It also thickens cervical mucus, which makes it harder for sperm to move and survive, and may also change the endometrium, making it harder for a fertilized egg to implant. Finally, when used in combination with estrogen, levonorgestrel works to reduce the risk of endometrial cancer.
When to interrupt dosage
The prescribed amount of Quasense is contingent upon the verified affliction, including Endometrial Hyperplasia, Emergency Contraception and Hypermenorrhea. The measure of dosage is dictated by the technique of delivery outlined in the table below.Condition
Dosage
Administration
Emergency Contraception
, 0.75 mg, 1.5 mg, 52.0 mg, 1.39 mg, 0.15 mg, 0.1 mg, 36.0 mg, 0.25 mg, 0.125 mg, 0.075 mg, 13.5 mg, 0.09 mg, 1.5 mg/mg, 19.5 mg, 0.0015 mg/hour, 0.03 mg, 0.05 mg, 0.45 mg, 2.6 mg, 0.3 mg
Oral, Kit - Oral, , Kit, Tablet, Tablet - Oral, Intrauterine, Intrauterine device, Intrauterine device - Intrauterine, Transdermal, Patch - Transdermal, Patch, Insert, extended release, Insert, extended release - Intrauterine, Subcutaneous, Implant, Implant - Subcutaneous, Tablet, film coated, Tablet, film coated - Oral
Endometrial Hyperplasia
, 0.75 mg, 1.5 mg, 52.0 mg, 1.39 mg, 0.15 mg, 0.1 mg, 36.0 mg, 0.25 mg, 0.125 mg, 0.075 mg, 13.5 mg, 0.09 mg, 1.5 mg/mg, 19.5 mg, 0.0015 mg/hour, 0.03 mg, 0.05 mg, 0.45 mg, 2.6 mg, 0.3 mg
Oral, Kit - Oral, , Kit, Tablet, Tablet - Oral, Intrauterine, Intrauterine device, Intrauterine device - Intrauterine, Transdermal, Patch - Transdermal, Patch, Insert, extended release, Insert, extended release - Intrauterine, Subcutaneous, Implant, Implant - Subcutaneous, Tablet, film coated, Tablet, film coated - Oral
Menopause
, 0.75 mg, 1.5 mg, 52.0 mg, 1.39 mg, 0.15 mg, 0.1 mg, 36.0 mg, 0.25 mg, 0.125 mg, 0.075 mg, 13.5 mg, 0.09 mg, 1.5 mg/mg, 19.5 mg, 0.0015 mg/hour, 0.03 mg, 0.05 mg, 0.45 mg, 2.6 mg, 0.3 mg
Oral, Kit - Oral, , Kit, Tablet, Tablet - Oral, Intrauterine, Intrauterine device, Intrauterine device - Intrauterine, Transdermal, Patch - Transdermal, Patch, Insert, extended release, Insert, extended release - Intrauterine, Subcutaneous, Implant, Implant - Subcutaneous, Tablet, film coated, Tablet, film coated - Oral
Hypermenorrhea
, 0.75 mg, 1.5 mg, 52.0 mg, 1.39 mg, 0.15 mg, 0.1 mg, 36.0 mg, 0.25 mg, 0.125 mg, 0.075 mg, 13.5 mg, 0.09 mg, 1.5 mg/mg, 19.5 mg, 0.0015 mg/hour, 0.03 mg, 0.05 mg, 0.45 mg, 2.6 mg, 0.3 mg
Oral, Kit - Oral, , Kit, Tablet, Tablet - Oral, Intrauterine, Intrauterine device, Intrauterine device - Intrauterine, Transdermal, Patch - Transdermal, Patch, Insert, extended release, Insert, extended release - Intrauterine, Subcutaneous, Implant, Implant - Subcutaneous, Tablet, film coated, Tablet, film coated - Oral
moderate Menopausal Vasomotor Symptoms
, 0.75 mg, 1.5 mg, 52.0 mg, 1.39 mg, 0.15 mg, 0.1 mg, 36.0 mg, 0.25 mg, 0.125 mg, 0.075 mg, 13.5 mg, 0.09 mg, 1.5 mg/mg, 19.5 mg, 0.0015 mg/hour, 0.03 mg, 0.05 mg, 0.45 mg, 2.6 mg, 0.3 mg
Oral, Kit - Oral, , Kit, Tablet, Tablet - Oral, Intrauterine, Intrauterine device, Intrauterine device - Intrauterine, Transdermal, Patch - Transdermal, Patch, Insert, extended release, Insert, extended release - Intrauterine, Subcutaneous, Implant, Implant - Subcutaneous, Tablet, film coated, Tablet, film coated - Oral
Postmenopausal Osteoporosis
, 0.75 mg, 1.5 mg, 52.0 mg, 1.39 mg, 0.15 mg, 0.1 mg, 36.0 mg, 0.25 mg, 0.125 mg, 0.075 mg, 13.5 mg, 0.09 mg, 1.5 mg/mg, 19.5 mg, 0.0015 mg/hour, 0.03 mg, 0.05 mg, 0.45 mg, 2.6 mg, 0.3 mg
Oral, Kit - Oral, , Kit, Tablet, Tablet - Oral, Intrauterine, Intrauterine device, Intrauterine device - Intrauterine, Transdermal, Patch - Transdermal, Patch, Insert, extended release, Insert, extended release - Intrauterine, Subcutaneous, Implant, Implant - Subcutaneous, Tablet, film coated, Tablet, film coated - Oral
Endometriosis
, 0.75 mg, 1.5 mg, 52.0 mg, 1.39 mg, 0.15 mg, 0.1 mg, 36.0 mg, 0.25 mg, 0.125 mg, 0.075 mg, 13.5 mg, 0.09 mg, 1.5 mg/mg, 19.5 mg, 0.0015 mg/hour, 0.03 mg, 0.05 mg, 0.45 mg, 2.6 mg, 0.3 mg
Oral, Kit - Oral, , Kit, Tablet, Tablet - Oral, Intrauterine, Intrauterine device, Intrauterine device - Intrauterine, Transdermal, Patch - Transdermal, Patch, Insert, extended release, Insert, extended release - Intrauterine, Subcutaneous, Implant, Implant - Subcutaneous, Tablet, film coated, Tablet, film coated - Oral
Has had at least 1 child
, 0.75 mg, 1.5 mg, 52.0 mg, 1.39 mg, 0.15 mg, 0.1 mg, 36.0 mg, 0.25 mg, 0.125 mg, 0.075 mg, 13.5 mg, 0.09 mg, 1.5 mg/mg, 19.5 mg, 0.0015 mg/hour, 0.03 mg, 0.05 mg, 0.45 mg, 2.6 mg, 0.3 mg
Oral, Kit - Oral, , Kit, Tablet, Tablet - Oral, Intrauterine, Intrauterine device, Intrauterine device - Intrauterine, Transdermal, Patch - Transdermal, Patch, Insert, extended release, Insert, extended release - Intrauterine, Subcutaneous, Implant, Implant - Subcutaneous, Tablet, film coated, Tablet, film coated - Oral
Hot flashes
, 0.75 mg, 1.5 mg, 52.0 mg, 1.39 mg, 0.15 mg, 0.1 mg, 36.0 mg, 0.25 mg, 0.125 mg, 0.075 mg, 13.5 mg, 0.09 mg, 1.5 mg/mg, 19.5 mg, 0.0015 mg/hour, 0.03 mg, 0.05 mg, 0.45 mg, 2.6 mg, 0.3 mg
Oral, Kit - Oral, , Kit, Tablet, Tablet - Oral, Intrauterine, Intrauterine device, Intrauterine device - Intrauterine, Transdermal, Patch - Transdermal, Patch, Insert, extended release, Insert, extended release - Intrauterine, Subcutaneous, Implant, Implant - Subcutaneous, Tablet, film coated, Tablet, film coated - Oral
Warnings
Quasense has forty-three contraindications, hence it should not be consumed while enduring any of the conditions specified in the following table.Quasense ContraindicationsCondition
Risk Level
Notes
Septic Abortion
Do Not Combine
undiagnosed abnormal genital bleeding
Do Not Combine
infected abortions
Do Not Combine
HCG elevated
Do Not Combine
Pelvic Infection
Do Not Combine
Vaginitis
Do Not Combine
Acute Coryza
Do Not Combine
presence or history of breast cancer
Do Not Combine
Uterine Cervicitis
Do Not Combine
Communicable Diseases
Do Not Combine
gonococcal cervical infection
Do Not Combine
Breast Cancer
Do Not Combine
Intrauterine Devices
Do Not Combine
Neoplasms, Hepatic
Do Not Combine
congenital or aquired uterine abnormality
Do Not Combine
Chlamydia Infections
Do Not Combine
Hypersensitivity
Do Not Combine
Emergency Contraception
Do Not Combine
Bacterial Endocarditis
Do Not Combine
lower genital tract infection
Do Not Combine
suspected pregnancy
Do Not Combine
Uterine Cervicitis
Do Not Combine
uterine neoplasia
Do Not Combine
Pelvic Inflammatory Disease
Do Not Combine
history of progestogen-sensitive breast cancer
Do Not Combine
Cervical Neoplasia
Do Not Combine
Fibroid Tumor
Do Not Combine
Postpartum Endometritis
Do Not Combine
chlamydial cervical infection
Do Not Combine
PAP Test Abnormalities
Do Not Combine
acute liver disease
Do Not Combine
Uterine anomaly distorting uterine cavity
Do Not Combine
Breast Cancer
Do Not Combine
Cervical Dysplasia
Do Not Combine
Thromboembolism
Do Not Combine
Bacterial Vaginosis
Do Not Combine
history of pelvic inflammatory disease
Do Not Combine
Breast
Do Not Combine
Vaginal Bleeding
Do Not Combine
Bacterial Vaginosis
Do Not Combine
Pelvic Inflammatory Disease
Do Not Combine
gonococcal cervical infection
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Levonorgestrel may interact with Pulse Frequency
Common Quasense Drug Interactions
Drug Name
Risk Level
Description
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Levonorgestrel.
Axitinib
Major
The metabolism of Axitinib can be decreased when combined with Levonorgestrel.
Cabazitaxel
Major
The metabolism of Cabazitaxel can be decreased when combined with Levonorgestrel.
Copanlisib
Major
The metabolism of Copanlisib can be decreased when combined with Levonorgestrel.
Crizotinib
Major
The metabolism of Crizotinib can be decreased when combined with Levonorgestrel.
Quasense Toxicity & Overdose RiskThe lowest toxic dose of levonorgestrel in rats has been found to be greater than 5000 mg/kg. An overdose of this drug may cause nausea and bleeding similar to a menstrual period. If someone overdoses, they should be provided with supportive care and the local poison control center should be contacted. There is no known antidote for a levonorgestrel overdose.
Quasense Novel Uses: Which Conditions Have a Clinical Trial Featuring Quasense?
99 active investigations are being conducted to assess the potential of Quasense to treat Postmenopausal Osteoporosis, Post-Partum Women and Endometrial Hyperplasia.Condition
Clinical Trials
Trial Phases
Endometriosis
32 Actively Recruiting
Phase 3, Not Applicable, Early Phase 1, Phase 2, Phase 4, Phase 1
Menopause
0 Actively Recruiting
Hot flashes
22 Actively Recruiting
Phase 2, Not Applicable, Phase 1, Phase 4, Early Phase 1
Has had at least 1 child
0 Actively Recruiting
Emergency Contraception
1 Actively Recruiting
Phase 4
Endometrial Hyperplasia
9 Actively Recruiting
Phase 2, Not Applicable
Hypermenorrhea
0 Actively Recruiting
Postmenopausal Osteoporosis
3 Actively Recruiting
Not Applicable, Phase 4
moderate Menopausal Vasomotor Symptoms
0 Actively Recruiting
Quasense Reviews: What are patients saying about Quasense?
5Patient Review
9/20/2013 I've been using this birth control for years with no problems. It's also the only one that ever helped with my morning sickness. I highly recommend it.
4.7Patient Review
12/24/2017 Quasense has been an amazing addition to my life for the past three months. It's helped with my acne, period pains, and flow-- all without any negative side effects like spotting or weight gain. I would highly recommend this birth control to anyone seeking a low-maintenance but effective solution.
4Patient Review
8/11/2013 I've been using this medication for four months now with mostly good results. My period symptoms have lightened, and I haven't experienced any extreme side effects; though I have put on some weight since starting the drug. The only downside is that it can be difficult to remember to take it at the same time every day.
3.3Patient Review
2/10/2018 Quasense has been my pill for about a year now, and I'm ready to move on. The weight gain and difficulty losing it, the acne, bloating, mood swings, and increased monthly spotting have all been frustrating side effects of this medication.
3Patient Review
10/10/2013 I've only been taking this pill for a week, but I have noticed some side effects like dizziness and numbness in my tongue. So far it's okay, but I take it at night so I don't have to deal with the headache during the day. My biggest worry was weight gain, but thankfully I haven't had any issues there.
3Patient Review
1/2/2014 I didn't like this because I got headaches almost every day. My libido decreased, and I felt terrible all the time. Additionally, my skin would clear up and then break out again the very next day.
2Patient Review
4/12/2014 I tried this for a month and was very disappointed. I had to leave school early the first day due to nausea and vomiting. My face also broke out more than it ever has while taking Quasense. Additionally, I don't gain weight easily, but I gained six pounds in one month while taking this medication. Overall, not recommended.
1Patient Review
7/26/2016 I gained a lot of weight, started bleeding constantly, and my depression got worse. I also developed chest and back acne, as well as weird bumps on my arms. Do not take this medication.
Patient Q&A Section about quasense
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is the generic for seasonique?
"is indicated for use by females of reproductive potential to prevent pregnancy.
SIMPESSE is indicated for use by females of reproductive potential for the prevention of pregnancy."
Answered by AI
What is seasonique prescribed for?
"Seasonique is a contraceptive pill that is taken once a week. It contains a lower dose of hormones than other birth control pills and also helps to regulate your periods. Seasonique may be used alone or with other medications. It is not known if Seasonique is safe and effective in children before menarche."
Answered by AI
What is Quasense generic for?
"QUASENSE (levonorgestrel and ethinyl estradiol) is an extended-cycle combination oral contraceptive that consists of 84 white active tablets (each containing 0.15 mg of levonorgestrel—a synthetic progestin—and 0.03 mg of ethinyl estradiol) and 7 peach inert tablets (without hormones)."
Answered by AI
Is Quasense discontinued?
"The Quasense brand name is no longer available in the United States. If the FDA has approved generic versions of this product, there may be generic equivalents available."
Answered by AI