Prolensa

Eye Pain, Cataract Surgery, Ocular Inflammation
Treatment
3 FDA approvals
6 Active Studies for Prolensa

What is Prolensa

BromfenacThe Generic name of this drug
Treatment SummaryBromfenac is an eye medication used to reduce pain and inflammation. It belongs to a class of drugs known as nonsteroidal anti-inflammatory drugs (NSAIDs). Ophthalmic NSAIDs are often used to manage ocular pain and inflammation after surgery and have a long track record of being safe and effective.
Xibromis the brand name
image of different drug pills on a surface
Prolensa Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Xibrom
Bromfenac
2005
19

Approved as Treatment by the FDA

Bromfenac, otherwise called Xibrom, is approved by the FDA for 3 uses including Ocular Inflammation and Eye Pain .
Ocular Inflammation
Eye Pain
Helps manage Eye Pain
Cataract Surgery
Helps manage Cataract Surgery

Effectiveness

How Prolensa Affects PatientsBromfenac ophthalmic solution is an eye drop that helps reduce inflammation. It is a non-steroidal anti-inflammatory drug (NSAID) and should be used as directed.
How Prolensa works in the bodyThe way this drug works is by stopping the body from making prostaglandins. Prostaglandins can cause inflammation in the eyes. In animal studies, they have been linked to increased eye pressure, increased blood flow, and increased permeability of the blood vessels in the eye. The drug blocks the substances that make prostaglandins, so less of them are made and the inflammation is reduced.

When to interrupt dosage

The prescribed amount of Prolensa is contingent upon the diagnosed condition, including Cataract Surgery, Eye Pain and Ocular Inflammation. The degree of dosage is contingent upon the delivery technique (e.g. Solution / drops - Ophthalmic or Solution / drops), as mentioned in the table underneath.
Condition
Dosage
Administration
Eye Pain
, 0.9 mg/mL, 1.035 mg/mL, 0.07 %, 0.7 mg/mL, 0.76 mg/mL, 0.75 mg/mL
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Solution, Solution - Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic
Cataract Surgery
, 0.9 mg/mL, 1.035 mg/mL, 0.07 %, 0.7 mg/mL, 0.76 mg/mL, 0.75 mg/mL
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Solution, Solution - Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic
Ocular Inflammation
, 0.9 mg/mL, 1.035 mg/mL, 0.07 %, 0.7 mg/mL, 0.76 mg/mL, 0.75 mg/mL
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Solution, Solution - Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic

Warnings

Prolensa Contraindications
Condition
Risk Level
Notes
Pulse Frequency
Do Not Combine
There are 20 known major drug interactions with Prolensa.
Common Prolensa Drug Interactions
Drug Name
Risk Level
Description
Valproic acid
Minor
The protein binding of Valproic acid can be decreased when combined with Bromfenac.
Aceclofenac
Moderate
The risk or severity of adverse effects can be increased when Bromfenac is combined with Aceclofenac.
Acemetacin
Moderate
The risk or severity of adverse effects can be increased when Bromfenac is combined with Acemetacin.
Acetylsalicylic acid
Moderate
The therapeutic efficacy of Acetylsalicylic acid can be decreased when used in combination with Bromfenac.
Alclofenac
Moderate
The risk or severity of adverse effects can be increased when Bromfenac is combined with Alclofenac.
image of a doctor in a lab doing drug, clinical research

Prolensa Novel Uses: Which Conditions Have a Clinical Trial Featuring Prolensa?

Seven active clinical trials are currently evaluating Prolensa as a potential treatment for Cataract Surgery, Ocular Pain and Inflammation.
Condition
Clinical Trials
Trial Phases
Eye Pain
2 Actively Recruiting
Not Applicable, Phase 4
Cataract Surgery
1 Actively Recruiting
Phase 4
Ocular Inflammation
3 Actively Recruiting
Phase 2, Phase 4, Phase 3

Prolensa Reviews: What are patients saying about Prolensa?

5Patient Review
12/10/2013
Prolensa for Inflammation of the Eye Following Surgery
I had surgery and used this treatment. I experienced no problems whatsoever. Thank you!
5Patient Review
6/21/2014
Prolensa for Inflammation of the Eye Following Surgery
Though this drug is effective, it's also very costly.
4.3Patient Review
2/23/2018
Prolensa for Postoperative Pain in Eye
Though it is very expensive, this medication does what it's supposed to do. I have yet to find a generic brand that works as well.
3.7Patient Review
1/24/2017
Prolensa for Inflammation of the Eye Following Surgery
I developed pain in both eyes after cataract surgery. My doctor recommended adding Durezol to my Prolensa routine. However, this only made my eyes more red, itchy, light sensitive, blurred, and twitching. They also became very dry. The post-operative effects have been a nightmare.
3.7Patient Review
6/5/2021
Prolensa for Inflammation of the Eye Following Surgery
The usual dosage on the box suggests using for 14 days, however I found that 0.6 ml was enough for me and only needed it for ten days after my cataract surgery. Unfortunately, because I ran out over the weekend, I wasn't able to get a prescription from my doctor until Monday.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about prolensa

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the generic drug for PROLENSA?

"Use one drop of generic bromfenac (0.09% strength) in the affected eye once a day."

Answered by AI

What is the drug PROLENSA used for?

"PROLENSA is a drug that helps to reduce inflammation and eye pain in patients who have recently had surgery to remove cataracts."

Answered by AI

How long should PROLENSA be used?

"Before cataract surgery, use one drop of Prolensa™ in the affected eye once a day. On the day of surgery, use one drop of Prolensa™ and one drop of Bromday®. For two weeks after surgery, use one drop of Prolensa™ once a day."

Answered by AI

Is PROLENSA a steroid?

"Prolensa is an eye medication used to treat swelling and pain caused by cataract surgery. It is a non-steroidal anti-inflammatory drug (NSAID). Prolensa may also be used for other purposes not listed in this guide."

Answered by AI

Clinical Trials for Prolensa

Have you considered Prolensa clinical trials? We made a collection of clinical trials featuring Prolensa, we think they might fit your search criteria.