Prezcobix

HIV
Treatment
1 FDA approval
20 Active Studies for Prezcobix

What is Prezcobix

DarunavirThe Generic name of this drug
Treatment SummaryCobicistat (brand name Tybost) is a medication used to treat HIV. It does not directly treat HIV, but instead increases the effectiveness of other medications taken to treat HIV. Cobicistat works by blocking certain enzymes in the body that break down HIV medications, allowing the HIV medications to work better and stay in the body longer. This means that lower doses of HIV medications can be taken, leading to fewer side effects.
Prezistais the brand name
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Prezcobix Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Prezista
Darunavir
2006
25

Approved as Treatment by the FDA

Darunavir, otherwise known as Prezista, is approved by the FDA for 1 uses which include HIV .
HIV
Used to treat Human Immunodeficiency Virus Type 1 (HIV-1) Infection in combination with Ritonavir

Effectiveness

How Prezcobix works in the bodyCobicistat acts as a blocker to stop certain enzymes in the body from breaking down other drugs. By blocking these enzymes, the body is able to maintain higher levels of those drugs, which in turn increases their effectiveness against HIV. Cobicistat itself does not have any direct anti-HIV activity.

When to interrupt dosage

The quantity of Prezcobix is contingent upon the diagnosed state. The dosage fluctuates, depending upon the delivery procedure outlined in the table beneath.
Condition
Dosage
Administration
HIV
, 400.0 mg, 600.0 mg, 75.0 mg, 150.0 mg, 800.0 mg, 300.0 mg, 100.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet - Oral, Tablet, Suspension, Suspension - Oral

Warnings

Prezcobix has twenty-five contraindications. Therefore, it should not be ingested when dealing with any of the afflictions found in the following table.Prezcobix Contraindications
Condition
Risk Level
Notes
Pulse Frequency
Do Not Combine
There are 20 known major drug interactions with Prezcobix.
Common Prezcobix Drug Interactions
Drug Name
Risk Level
Description
1,2-Benzodiazepine
Major
The metabolism of 1,2-Benzodiazepine can be decreased when combined with Darunavir.
3,5-diiodothyropropionic acid
Major
The metabolism of 3,5-diiodothyropropionic acid can be decreased when combined with Darunavir.
5-androstenedione
Major
The metabolism of 5-androstenedione can be decreased when combined with Darunavir.
6-O-benzylguanine
Major
The metabolism of 6-O-benzylguanine can be decreased when combined with Darunavir.
7-ethyl-10-hydroxycamptothecin
Major
The metabolism of 7-ethyl-10-hydroxycamptothecin can be decreased when combined with Darunavir.
Prezcobix Toxicity & Overdose RiskSome of the most commonly reported side effects of this drug include yellowing of the skin and eyes (jaundice) in 13% of patients, yellowing of the eyes (ocular icterus) in 15%, and nausea in 12%.
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Prezcobix Novel Uses: Which Conditions Have a Clinical Trial Featuring Prezcobix?

165 active research studies are currently exploring the efficacy of Prezcobix for management of HIV.
Condition
Clinical Trials
Trial Phases
HIV
40 Actively Recruiting
Phase 2, Phase 3, Phase 1, Phase 4, Not Applicable, Early Phase 1

Prezcobix Reviews: What are patients saying about Prezcobix?

5Patient Review
7/15/2017
Prezcobix for HIV
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about prezcobix

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Prezcobix an antiretroviral?

"Immune reconstitution syndrome, which can occur when patients treated with combination antiretroviral therapy, including PREZCOBIX, start to rebuild their immune system, has been reported."

Answered by AI

What drugs are in Prezcobix?

"This product combines two drugs, darunavir and cobicistat. Darunavir is a protease inhibitor, while cobicistat is used to increase levels of darunavir."

Answered by AI

Is Prezcobix a generic?

"There is no version of Prezcobix that is therapeutically equivalent in the United States. There may be some online pharmacies that fraudulentlysell an illegal generic version of Prezcobix, but these medications may be counterfeit and unsafe."

Answered by AI

What is Prezcobix used for?

"Prezcobix is a prescription medicine that is used in conjunction with other drugs to treat HIV-1 infection in adults and children who weigh at least 88 pounds."

Answered by AI

Clinical Trials for Prezcobix

Have you considered Prezcobix clinical trials? We made a collection of clinical trials featuring Prezcobix, we think they might fit your search criteria.
Have you considered Prezcobix clinical trials? We made a collection of clinical trials featuring Prezcobix, we think they might fit your search criteria.
Have you considered Prezcobix clinical trials? We made a collection of clinical trials featuring Prezcobix, we think they might fit your search criteria.
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