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What is Nitro-Bid
NitroglycerinThe Generic name of this drug
Treatment SummaryNitroglycerin is a medication used to open up blood vessels and lower high blood pressure. It was first approved by the FDA in 2000 and is available in various forms, such as a spray, tablets, injections, and ointment. The ointment form is used to treat the pain caused by anal fissures and was approved by the FDA in 1955. Nitroglycerin is typically marketed by Pfizer and other companies, depending on the dosage form.
Nitroglycerinis the brand name
Nitro-Bid Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Nitroglycerin
Nitroglycerin
1981
182
Effectiveness
How Nitro-Bid Affects PatientsNitroglycerin relaxes the blood vessels, increasing blood flow to the heart and reducing the amount of work it needs to do. Nitroglycerin can also reduce coronary artery spasm and lower both systolic and diastolic blood pressure. However, long-term use of nitroglycerin can lead to reduced effectiveness and can have pro-oxidant effects, as well as causing damage to the blood vessels.
How Nitro-Bid works in the bodyNitroglycerin works by converting into nitric oxide, which relaxes and widens the blood vessels. This increases the flow of blood and decreases pressure in the heart. Nitric oxide also triggers the enzyme guanylate cyclase, which produces a molecule called cyclic guanosine monophosphate, which helps further relax and widen the blood vessels. This process also helps the body remove excess water and salt.
When to interrupt dosage
The recommended dosage of Nitro-Bid is subject to the determined condition, including Coronary Artery Spasm, induction of Uterine relaxation and Anal Fissure. The magnitude of dosage depends upon the technique of delivery (e.g. Tablet or Tablet - Oral) listed in the underneath table.Condition
Dosage
Administration
induction of Intraoperative Hypotension
, 160.0 mg, 20.0 mg, 40.0 mg, 60.0 mg, 80.0 mg, 120.0 mg, 0.02 mg/mg, 0.1 mg/hour, 0.2 mg/hour, 0.4 mg/hour, 0.6 mg/hour, 2.5 mg, 9.0 mg, 6.5 mg, 0.4 mg, 0.25 mg/hour, 0.5 mg/hour, 1.0 mg/hour, 1.5 mg/hour, 0.004 mg/mg, 0.3 mg, 5.0 mg/mL, 37.4 mg, 20.8 mg, 50.0 mg, 1.0 mg, 2.0 %, 0.6 mg, 75.0 mg, 54.0 mg, 36.0 mg, 18.0 mg, 25.0 mg, 2.6 mg, 100.0 mg, 0.1 mg/mL, 0.2 mg/mL, 0.4 mg/mL, 0.0004 mg/mg, 18.0 mg/[USP'U], 12.5 mg, 1.0 mg/mL, 0.8 mg/hour, 7.2 mg/cm2, 0.4 mg/pump actuation, 6.0 mg/cm2
, Transdermal, Patch, Patch - Transdermal, Topical, Ointment, Ointment - Topical, Oral, Capsule, Capsule - Oral, Sublingual, Tablet - Sublingual, Tablet, Spray, Spray - Oral, Tablet - Oral, Aerosol, metered, Aerosol, metered - Sublingual, Spray, metered, Spray, metered - Oral, Ointment - Rectal, Rectal, Spray, metered - Sublingual, Tablet, orally disintegrating, Tablet, orally disintegrating - Sublingual, Intravenous, Injection, solution, Injection, solution - Intravenous, Film, extended release, Film, extended release - Transdermal, Patch, extended release, Patch, extended release - Transdermal, Liquid, Liquid - Intravenous, Solution, Solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Buccal, Tablet, extended release - Buccal, Injection, Injection - Intravenous, Powder, Powder - Sublingual, Transmucosal, Aerosol, spray, Aerosol, spray - Transmucosal, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous
prophylaxis of Angina pectoris
, 160.0 mg, 20.0 mg, 40.0 mg, 60.0 mg, 80.0 mg, 120.0 mg, 0.02 mg/mg, 0.1 mg/hour, 0.2 mg/hour, 0.4 mg/hour, 0.6 mg/hour, 2.5 mg, 9.0 mg, 6.5 mg, 0.4 mg, 0.25 mg/hour, 0.5 mg/hour, 1.0 mg/hour, 1.5 mg/hour, 0.004 mg/mg, 0.3 mg, 5.0 mg/mL, 37.4 mg, 20.8 mg, 50.0 mg, 1.0 mg, 2.0 %, 0.6 mg, 75.0 mg, 54.0 mg, 36.0 mg, 18.0 mg, 25.0 mg, 2.6 mg, 100.0 mg, 0.1 mg/mL, 0.2 mg/mL, 0.4 mg/mL, 0.0004 mg/mg, 18.0 mg/[USP'U], 12.5 mg, 1.0 mg/mL, 0.8 mg/hour, 7.2 mg/cm2, 0.4 mg/pump actuation, 6.0 mg/cm2
, Transdermal, Patch, Patch - Transdermal, Topical, Ointment, Ointment - Topical, Oral, Capsule, Capsule - Oral, Sublingual, Tablet - Sublingual, Tablet, Spray, Spray - Oral, Tablet - Oral, Aerosol, metered, Aerosol, metered - Sublingual, Spray, metered, Spray, metered - Oral, Ointment - Rectal, Rectal, Spray, metered - Sublingual, Tablet, orally disintegrating, Tablet, orally disintegrating - Sublingual, Intravenous, Injection, solution, Injection, solution - Intravenous, Film, extended release, Film, extended release - Transdermal, Patch, extended release, Patch, extended release - Transdermal, Liquid, Liquid - Intravenous, Solution, Solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Buccal, Tablet, extended release - Buccal, Injection, Injection - Intravenous, Powder, Powder - Sublingual, Transmucosal, Aerosol, spray, Aerosol, spray - Transmucosal, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous
Congestive Heart Failure
, 160.0 mg, 20.0 mg, 40.0 mg, 60.0 mg, 80.0 mg, 120.0 mg, 0.02 mg/mg, 0.1 mg/hour, 0.2 mg/hour, 0.4 mg/hour, 0.6 mg/hour, 2.5 mg, 9.0 mg, 6.5 mg, 0.4 mg, 0.25 mg/hour, 0.5 mg/hour, 1.0 mg/hour, 1.5 mg/hour, 0.004 mg/mg, 0.3 mg, 5.0 mg/mL, 37.4 mg, 20.8 mg, 50.0 mg, 1.0 mg, 2.0 %, 0.6 mg, 75.0 mg, 54.0 mg, 36.0 mg, 18.0 mg, 25.0 mg, 2.6 mg, 100.0 mg, 0.1 mg/mL, 0.2 mg/mL, 0.4 mg/mL, 0.0004 mg/mg, 18.0 mg/[USP'U], 12.5 mg, 1.0 mg/mL, 0.8 mg/hour, 7.2 mg/cm2, 0.4 mg/pump actuation, 6.0 mg/cm2
, Transdermal, Patch, Patch - Transdermal, Topical, Ointment, Ointment - Topical, Oral, Capsule, Capsule - Oral, Sublingual, Tablet - Sublingual, Tablet, Spray, Spray - Oral, Tablet - Oral, Aerosol, metered, Aerosol, metered - Sublingual, Spray, metered, Spray, metered - Oral, Ointment - Rectal, Rectal, Spray, metered - Sublingual, Tablet, orally disintegrating, Tablet, orally disintegrating - Sublingual, Intravenous, Injection, solution, Injection, solution - Intravenous, Film, extended release, Film, extended release - Transdermal, Patch, extended release, Patch, extended release - Transdermal, Liquid, Liquid - Intravenous, Solution, Solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Buccal, Tablet, extended release - Buccal, Injection, Injection - Intravenous, Powder, Powder - Sublingual, Transmucosal, Aerosol, spray, Aerosol, spray - Transmucosal, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous
Chest Pain
, 160.0 mg, 20.0 mg, 40.0 mg, 60.0 mg, 80.0 mg, 120.0 mg, 0.02 mg/mg, 0.1 mg/hour, 0.2 mg/hour, 0.4 mg/hour, 0.6 mg/hour, 2.5 mg, 9.0 mg, 6.5 mg, 0.4 mg, 0.25 mg/hour, 0.5 mg/hour, 1.0 mg/hour, 1.5 mg/hour, 0.004 mg/mg, 0.3 mg, 5.0 mg/mL, 37.4 mg, 20.8 mg, 50.0 mg, 1.0 mg, 2.0 %, 0.6 mg, 75.0 mg, 54.0 mg, 36.0 mg, 18.0 mg, 25.0 mg, 2.6 mg, 100.0 mg, 0.1 mg/mL, 0.2 mg/mL, 0.4 mg/mL, 0.0004 mg/mg, 18.0 mg/[USP'U], 12.5 mg, 1.0 mg/mL, 0.8 mg/hour, 7.2 mg/cm2, 0.4 mg/pump actuation, 6.0 mg/cm2
, Transdermal, Patch, Patch - Transdermal, Topical, Ointment, Ointment - Topical, Oral, Capsule, Capsule - Oral, Sublingual, Tablet - Sublingual, Tablet, Spray, Spray - Oral, Tablet - Oral, Aerosol, metered, Aerosol, metered - Sublingual, Spray, metered, Spray, metered - Oral, Ointment - Rectal, Rectal, Spray, metered - Sublingual, Tablet, orally disintegrating, Tablet, orally disintegrating - Sublingual, Intravenous, Injection, solution, Injection, solution - Intravenous, Film, extended release, Film, extended release - Transdermal, Patch, extended release, Patch, extended release - Transdermal, Liquid, Liquid - Intravenous, Solution, Solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Buccal, Tablet, extended release - Buccal, Injection, Injection - Intravenous, Powder, Powder - Sublingual, Transmucosal, Aerosol, spray, Aerosol, spray - Transmucosal, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous
Coronary Artery Disease (CAD)
, 160.0 mg, 20.0 mg, 40.0 mg, 60.0 mg, 80.0 mg, 120.0 mg, 0.02 mg/mg, 0.1 mg/hour, 0.2 mg/hour, 0.4 mg/hour, 0.6 mg/hour, 2.5 mg, 9.0 mg, 6.5 mg, 0.4 mg, 0.25 mg/hour, 0.5 mg/hour, 1.0 mg/hour, 1.5 mg/hour, 0.004 mg/mg, 0.3 mg, 5.0 mg/mL, 37.4 mg, 20.8 mg, 50.0 mg, 1.0 mg, 2.0 %, 0.6 mg, 75.0 mg, 54.0 mg, 36.0 mg, 18.0 mg, 25.0 mg, 2.6 mg, 100.0 mg, 0.1 mg/mL, 0.2 mg/mL, 0.4 mg/mL, 0.0004 mg/mg, 18.0 mg/[USP'U], 12.5 mg, 1.0 mg/mL, 0.8 mg/hour, 7.2 mg/cm2, 0.4 mg/pump actuation, 6.0 mg/cm2
, Transdermal, Patch, Patch - Transdermal, Topical, Ointment, Ointment - Topical, Oral, Capsule, Capsule - Oral, Sublingual, Tablet - Sublingual, Tablet, Spray, Spray - Oral, Tablet - Oral, Aerosol, metered, Aerosol, metered - Sublingual, Spray, metered, Spray, metered - Oral, Ointment - Rectal, Rectal, Spray, metered - Sublingual, Tablet, orally disintegrating, Tablet, orally disintegrating - Sublingual, Intravenous, Injection, solution, Injection, solution - Intravenous, Film, extended release, Film, extended release - Transdermal, Patch, extended release, Patch, extended release - Transdermal, Liquid, Liquid - Intravenous, Solution, Solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Buccal, Tablet, extended release - Buccal, Injection, Injection - Intravenous, Powder, Powder - Sublingual, Transmucosal, Aerosol, spray, Aerosol, spray - Transmucosal, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous
Hypotension
, 160.0 mg, 20.0 mg, 40.0 mg, 60.0 mg, 80.0 mg, 120.0 mg, 0.02 mg/mg, 0.1 mg/hour, 0.2 mg/hour, 0.4 mg/hour, 0.6 mg/hour, 2.5 mg, 9.0 mg, 6.5 mg, 0.4 mg, 0.25 mg/hour, 0.5 mg/hour, 1.0 mg/hour, 1.5 mg/hour, 0.004 mg/mg, 0.3 mg, 5.0 mg/mL, 37.4 mg, 20.8 mg, 50.0 mg, 1.0 mg, 2.0 %, 0.6 mg, 75.0 mg, 54.0 mg, 36.0 mg, 18.0 mg, 25.0 mg, 2.6 mg, 100.0 mg, 0.1 mg/mL, 0.2 mg/mL, 0.4 mg/mL, 0.0004 mg/mg, 18.0 mg/[USP'U], 12.5 mg, 1.0 mg/mL, 0.8 mg/hour, 7.2 mg/cm2, 0.4 mg/pump actuation, 6.0 mg/cm2
, Transdermal, Patch, Patch - Transdermal, Topical, Ointment, Ointment - Topical, Oral, Capsule, Capsule - Oral, Sublingual, Tablet - Sublingual, Tablet, Spray, Spray - Oral, Tablet - Oral, Aerosol, metered, Aerosol, metered - Sublingual, Spray, metered, Spray, metered - Oral, Ointment - Rectal, Rectal, Spray, metered - Sublingual, Tablet, orally disintegrating, Tablet, orally disintegrating - Sublingual, Intravenous, Injection, solution, Injection, solution - Intravenous, Film, extended release, Film, extended release - Transdermal, Patch, extended release, Patch, extended release - Transdermal, Liquid, Liquid - Intravenous, Solution, Solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Buccal, Tablet, extended release - Buccal, Injection, Injection - Intravenous, Powder, Powder - Sublingual, Transmucosal, Aerosol, spray, Aerosol, spray - Transmucosal, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous
Anal Fissure
, 160.0 mg, 20.0 mg, 40.0 mg, 60.0 mg, 80.0 mg, 120.0 mg, 0.02 mg/mg, 0.1 mg/hour, 0.2 mg/hour, 0.4 mg/hour, 0.6 mg/hour, 2.5 mg, 9.0 mg, 6.5 mg, 0.4 mg, 0.25 mg/hour, 0.5 mg/hour, 1.0 mg/hour, 1.5 mg/hour, 0.004 mg/mg, 0.3 mg, 5.0 mg/mL, 37.4 mg, 20.8 mg, 50.0 mg, 1.0 mg, 2.0 %, 0.6 mg, 75.0 mg, 54.0 mg, 36.0 mg, 18.0 mg, 25.0 mg, 2.6 mg, 100.0 mg, 0.1 mg/mL, 0.2 mg/mL, 0.4 mg/mL, 0.0004 mg/mg, 18.0 mg/[USP'U], 12.5 mg, 1.0 mg/mL, 0.8 mg/hour, 7.2 mg/cm2, 0.4 mg/pump actuation, 6.0 mg/cm2
, Transdermal, Patch, Patch - Transdermal, Topical, Ointment, Ointment - Topical, Oral, Capsule, Capsule - Oral, Sublingual, Tablet - Sublingual, Tablet, Spray, Spray - Oral, Tablet - Oral, Aerosol, metered, Aerosol, metered - Sublingual, Spray, metered, Spray, metered - Oral, Ointment - Rectal, Rectal, Spray, metered - Sublingual, Tablet, orally disintegrating, Tablet, orally disintegrating - Sublingual, Intravenous, Injection, solution, Injection, solution - Intravenous, Film, extended release, Film, extended release - Transdermal, Patch, extended release, Patch, extended release - Transdermal, Liquid, Liquid - Intravenous, Solution, Solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Buccal, Tablet, extended release - Buccal, Injection, Injection - Intravenous, Powder, Powder - Sublingual, Transmucosal, Aerosol, spray, Aerosol, spray - Transmucosal, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous
Hypertensive disease
, 160.0 mg, 20.0 mg, 40.0 mg, 60.0 mg, 80.0 mg, 120.0 mg, 0.02 mg/mg, 0.1 mg/hour, 0.2 mg/hour, 0.4 mg/hour, 0.6 mg/hour, 2.5 mg, 9.0 mg, 6.5 mg, 0.4 mg, 0.25 mg/hour, 0.5 mg/hour, 1.0 mg/hour, 1.5 mg/hour, 0.004 mg/mg, 0.3 mg, 5.0 mg/mL, 37.4 mg, 20.8 mg, 50.0 mg, 1.0 mg, 2.0 %, 0.6 mg, 75.0 mg, 54.0 mg, 36.0 mg, 18.0 mg, 25.0 mg, 2.6 mg, 100.0 mg, 0.1 mg/mL, 0.2 mg/mL, 0.4 mg/mL, 0.0004 mg/mg, 18.0 mg/[USP'U], 12.5 mg, 1.0 mg/mL, 0.8 mg/hour, 7.2 mg/cm2, 0.4 mg/pump actuation, 6.0 mg/cm2
, Transdermal, Patch, Patch - Transdermal, Topical, Ointment, Ointment - Topical, Oral, Capsule, Capsule - Oral, Sublingual, Tablet - Sublingual, Tablet, Spray, Spray - Oral, Tablet - Oral, Aerosol, metered, Aerosol, metered - Sublingual, Spray, metered, Spray, metered - Oral, Ointment - Rectal, Rectal, Spray, metered - Sublingual, Tablet, orally disintegrating, Tablet, orally disintegrating - Sublingual, Intravenous, Injection, solution, Injection, solution - Intravenous, Film, extended release, Film, extended release - Transdermal, Patch, extended release, Patch, extended release - Transdermal, Liquid, Liquid - Intravenous, Solution, Solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Buccal, Tablet, extended release - Buccal, Injection, Injection - Intravenous, Powder, Powder - Sublingual, Transmucosal, Aerosol, spray, Aerosol, spray - Transmucosal, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous
Myocardial Infarction
, 160.0 mg, 20.0 mg, 40.0 mg, 60.0 mg, 80.0 mg, 120.0 mg, 0.02 mg/mg, 0.1 mg/hour, 0.2 mg/hour, 0.4 mg/hour, 0.6 mg/hour, 2.5 mg, 9.0 mg, 6.5 mg, 0.4 mg, 0.25 mg/hour, 0.5 mg/hour, 1.0 mg/hour, 1.5 mg/hour, 0.004 mg/mg, 0.3 mg, 5.0 mg/mL, 37.4 mg, 20.8 mg, 50.0 mg, 1.0 mg, 2.0 %, 0.6 mg, 75.0 mg, 54.0 mg, 36.0 mg, 18.0 mg, 25.0 mg, 2.6 mg, 100.0 mg, 0.1 mg/mL, 0.2 mg/mL, 0.4 mg/mL, 0.0004 mg/mg, 18.0 mg/[USP'U], 12.5 mg, 1.0 mg/mL, 0.8 mg/hour, 7.2 mg/cm2, 0.4 mg/pump actuation, 6.0 mg/cm2
, Transdermal, Patch, Patch - Transdermal, Topical, Ointment, Ointment - Topical, Oral, Capsule, Capsule - Oral, Sublingual, Tablet - Sublingual, Tablet, Spray, Spray - Oral, Tablet - Oral, Aerosol, metered, Aerosol, metered - Sublingual, Spray, metered, Spray, metered - Oral, Ointment - Rectal, Rectal, Spray, metered - Sublingual, Tablet, orally disintegrating, Tablet, orally disintegrating - Sublingual, Intravenous, Injection, solution, Injection, solution - Intravenous, Film, extended release, Film, extended release - Transdermal, Patch, extended release, Patch, extended release - Transdermal, Liquid, Liquid - Intravenous, Solution, Solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Buccal, Tablet, extended release - Buccal, Injection, Injection - Intravenous, Powder, Powder - Sublingual, Transmucosal, Aerosol, spray, Aerosol, spray - Transmucosal, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous
insufficient response to beta-blockers
, 160.0 mg, 20.0 mg, 40.0 mg, 60.0 mg, 80.0 mg, 120.0 mg, 0.02 mg/mg, 0.1 mg/hour, 0.2 mg/hour, 0.4 mg/hour, 0.6 mg/hour, 2.5 mg, 9.0 mg, 6.5 mg, 0.4 mg, 0.25 mg/hour, 0.5 mg/hour, 1.0 mg/hour, 1.5 mg/hour, 0.004 mg/mg, 0.3 mg, 5.0 mg/mL, 37.4 mg, 20.8 mg, 50.0 mg, 1.0 mg, 2.0 %, 0.6 mg, 75.0 mg, 54.0 mg, 36.0 mg, 18.0 mg, 25.0 mg, 2.6 mg, 100.0 mg, 0.1 mg/mL, 0.2 mg/mL, 0.4 mg/mL, 0.0004 mg/mg, 18.0 mg/[USP'U], 12.5 mg, 1.0 mg/mL, 0.8 mg/hour, 7.2 mg/cm2, 0.4 mg/pump actuation, 6.0 mg/cm2
, Transdermal, Patch, Patch - Transdermal, Topical, Ointment, Ointment - Topical, Oral, Capsule, Capsule - Oral, Sublingual, Tablet - Sublingual, Tablet, Spray, Spray - Oral, Tablet - Oral, Aerosol, metered, Aerosol, metered - Sublingual, Spray, metered, Spray, metered - Oral, Ointment - Rectal, Rectal, Spray, metered - Sublingual, Tablet, orally disintegrating, Tablet, orally disintegrating - Sublingual, Intravenous, Injection, solution, Injection, solution - Intravenous, Film, extended release, Film, extended release - Transdermal, Patch, extended release, Patch, extended release - Transdermal, Liquid, Liquid - Intravenous, Solution, Solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Buccal, Tablet, extended release - Buccal, Injection, Injection - Intravenous, Powder, Powder - Sublingual, Transmucosal, Aerosol, spray, Aerosol, spray - Transmucosal, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous
nitroglycerin
, 160.0 mg, 20.0 mg, 40.0 mg, 60.0 mg, 80.0 mg, 120.0 mg, 0.02 mg/mg, 0.1 mg/hour, 0.2 mg/hour, 0.4 mg/hour, 0.6 mg/hour, 2.5 mg, 9.0 mg, 6.5 mg, 0.4 mg, 0.25 mg/hour, 0.5 mg/hour, 1.0 mg/hour, 1.5 mg/hour, 0.004 mg/mg, 0.3 mg, 5.0 mg/mL, 37.4 mg, 20.8 mg, 50.0 mg, 1.0 mg, 2.0 %, 0.6 mg, 75.0 mg, 54.0 mg, 36.0 mg, 18.0 mg, 25.0 mg, 2.6 mg, 100.0 mg, 0.1 mg/mL, 0.2 mg/mL, 0.4 mg/mL, 0.0004 mg/mg, 18.0 mg/[USP'U], 12.5 mg, 1.0 mg/mL, 0.8 mg/hour, 7.2 mg/cm2, 0.4 mg/pump actuation, 6.0 mg/cm2
, Transdermal, Patch, Patch - Transdermal, Topical, Ointment, Ointment - Topical, Oral, Capsule, Capsule - Oral, Sublingual, Tablet - Sublingual, Tablet, Spray, Spray - Oral, Tablet - Oral, Aerosol, metered, Aerosol, metered - Sublingual, Spray, metered, Spray, metered - Oral, Ointment - Rectal, Rectal, Spray, metered - Sublingual, Tablet, orally disintegrating, Tablet, orally disintegrating - Sublingual, Intravenous, Injection, solution, Injection, solution - Intravenous, Film, extended release, Film, extended release - Transdermal, Patch, extended release, Patch, extended release - Transdermal, Liquid, Liquid - Intravenous, Solution, Solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Buccal, Tablet, extended release - Buccal, Injection, Injection - Intravenous, Powder, Powder - Sublingual, Transmucosal, Aerosol, spray, Aerosol, spray - Transmucosal, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous
Pain
, 160.0 mg, 20.0 mg, 40.0 mg, 60.0 mg, 80.0 mg, 120.0 mg, 0.02 mg/mg, 0.1 mg/hour, 0.2 mg/hour, 0.4 mg/hour, 0.6 mg/hour, 2.5 mg, 9.0 mg, 6.5 mg, 0.4 mg, 0.25 mg/hour, 0.5 mg/hour, 1.0 mg/hour, 1.5 mg/hour, 0.004 mg/mg, 0.3 mg, 5.0 mg/mL, 37.4 mg, 20.8 mg, 50.0 mg, 1.0 mg, 2.0 %, 0.6 mg, 75.0 mg, 54.0 mg, 36.0 mg, 18.0 mg, 25.0 mg, 2.6 mg, 100.0 mg, 0.1 mg/mL, 0.2 mg/mL, 0.4 mg/mL, 0.0004 mg/mg, 18.0 mg/[USP'U], 12.5 mg, 1.0 mg/mL, 0.8 mg/hour, 7.2 mg/cm2, 0.4 mg/pump actuation, 6.0 mg/cm2
, Transdermal, Patch, Patch - Transdermal, Topical, Ointment, Ointment - Topical, Oral, Capsule, Capsule - Oral, Sublingual, Tablet - Sublingual, Tablet, Spray, Spray - Oral, Tablet - Oral, Aerosol, metered, Aerosol, metered - Sublingual, Spray, metered, Spray, metered - Oral, Ointment - Rectal, Rectal, Spray, metered - Sublingual, Tablet, orally disintegrating, Tablet, orally disintegrating - Sublingual, Intravenous, Injection, solution, Injection, solution - Intravenous, Film, extended release, Film, extended release - Transdermal, Patch, extended release, Patch, extended release - Transdermal, Liquid, Liquid - Intravenous, Solution, Solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Buccal, Tablet, extended release - Buccal, Injection, Injection - Intravenous, Powder, Powder - Sublingual, Transmucosal, Aerosol, spray, Aerosol, spray - Transmucosal, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous
Angina Attacks
, 160.0 mg, 20.0 mg, 40.0 mg, 60.0 mg, 80.0 mg, 120.0 mg, 0.02 mg/mg, 0.1 mg/hour, 0.2 mg/hour, 0.4 mg/hour, 0.6 mg/hour, 2.5 mg, 9.0 mg, 6.5 mg, 0.4 mg, 0.25 mg/hour, 0.5 mg/hour, 1.0 mg/hour, 1.5 mg/hour, 0.004 mg/mg, 0.3 mg, 5.0 mg/mL, 37.4 mg, 20.8 mg, 50.0 mg, 1.0 mg, 2.0 %, 0.6 mg, 75.0 mg, 54.0 mg, 36.0 mg, 18.0 mg, 25.0 mg, 2.6 mg, 100.0 mg, 0.1 mg/mL, 0.2 mg/mL, 0.4 mg/mL, 0.0004 mg/mg, 18.0 mg/[USP'U], 12.5 mg, 1.0 mg/mL, 0.8 mg/hour, 7.2 mg/cm2, 0.4 mg/pump actuation, 6.0 mg/cm2
, Transdermal, Patch, Patch - Transdermal, Topical, Ointment, Ointment - Topical, Oral, Capsule, Capsule - Oral, Sublingual, Tablet - Sublingual, Tablet, Spray, Spray - Oral, Tablet - Oral, Aerosol, metered, Aerosol, metered - Sublingual, Spray, metered, Spray, metered - Oral, Ointment - Rectal, Rectal, Spray, metered - Sublingual, Tablet, orally disintegrating, Tablet, orally disintegrating - Sublingual, Intravenous, Injection, solution, Injection, solution - Intravenous, Film, extended release, Film, extended release - Transdermal, Patch, extended release, Patch, extended release - Transdermal, Liquid, Liquid - Intravenous, Solution, Solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Buccal, Tablet, extended release - Buccal, Injection, Injection - Intravenous, Powder, Powder - Sublingual, Transmucosal, Aerosol, spray, Aerosol, spray - Transmucosal, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous
Warnings
Nitro-Bid has eleven contraindications and should not be employed in conjunction with the conditions outlined in the subsequent table.Nitro-Bid ContraindicationsCondition
Risk Level
Notes
pericardial tamponade
Do Not Combine
Pulse Frequency
Do Not Combine
Hypovolemic Shock
Do Not Combine
Anemia
Do Not Combine
Pick Disease of Heart
Do Not Combine
Pulse Frequency
Do Not Combine
Acute Circulatory Failure
Do Not Combine
Intracranial Hypertension
Do Not Combine
Cardiomyopathy, Restrictive
Do Not Combine
Myocardial Infarction
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Nitroglycerin may interact with Pulse Frequency
Common Nitro-Bid Drug Interactions
Drug Name
Risk Level
Description
Amediplase
Major
The therapeutic efficacy of Amediplase can be decreased when used in combination with Nitroglycerin.
Amifostine
Major
Nitroglycerin may increase the hypotensive activities of Amifostine.
Desmoteplase
Major
The therapeutic efficacy of Desmoteplase can be decreased when used in combination with Nitroglycerin.
Reteplase
Major
The therapeutic efficacy of Reteplase can be decreased when used in combination with Nitroglycerin.
Riociguat
Major
Nitroglycerin may increase the hypotensive activities of Riociguat.
Nitro-Bid Toxicity & Overdose RiskThe lowest toxic dose of nitroglycerin in rats is 105mg/kg orally and 23.2mg/kg intravenously. An overdose of nitroglycerin can lead to severe low blood pressure, a throbbing headache, dizziness, an irregular heartbeat, confusion, paralysis, and even death. Other symptoms can include flushing of the skin, nausea and vomiting, slow breathing, and a blue tint to the skin due to methemoglobinemia. There is no known antidote for nitroglycerin overdose, so treatment consists of managing hypotension and other symptoms with supportive care such as elevating the legs and providing
Nitro-Bid Novel Uses: Which Conditions Have a Clinical Trial Featuring Nitro-Bid?
38 active clinical trials are presently analyzing the potential of Nitro-Bid to prevent Gastroesophageal Variceal Hemorrhage, reduce Hypotension and improve Congestive Heart Failure outcomes.Condition
Clinical Trials
Trial Phases
Congestive Heart Failure
23 Actively Recruiting
Phase 2, Phase 3, Not Applicable, Phase 1
Myocardial Infarction
0 Actively Recruiting
Anal Fissure
0 Actively Recruiting
Chest Pain
6 Actively Recruiting
Phase 2, Phase 3, Not Applicable, Phase 4
insufficient response to beta-blockers
0 Actively Recruiting
Hypotension
1 Actively Recruiting
Early Phase 1
Coronary Artery Disease (CAD)
1 Actively Recruiting
Not Applicable
induction of Intraoperative Hypotension
0 Actively Recruiting
prophylaxis of Angina pectoris
0 Actively Recruiting
nitroglycerin
0 Actively Recruiting
Hypertensive disease
0 Actively Recruiting
Angina Attacks
0 Actively Recruiting
Pain
0 Actively Recruiting
Nitro-Bid Reviews: What are patients saying about Nitro-Bid?
4.3Patient Review
1/3/2010 I've been using this treatment for two years now, and I have to say that it's been effective for me. However, I have noticed some side effects, such as fatigue and rectal itching. Overall, though, I'm pleased with the results.
2.3Patient Review
9/2/2008 Unfortunately, I had a really terrible experience with this ointment. I think it interacted badly with my anti-seizure medication and caused me to have a debilitating headache and vomit for four hours straight. While my anal fissure did feel better afterwards, the rest of me felt awful.
2.3Patient Review
11/28/2011 After using this, I felt a burning sensation followed by a headache.
2.3Patient Review
10/23/20071.3Patient Review
9/25/2013 This medication only partially numbed the pain of my anal fissure, and it came with a lot of throbbing. Not worth it in my opinion.
1Patient Review
6/23/2011 I was really scared to try this treatment, but after reading all of the reviews, I decided to go for it. Thank you so much for sharing your experiences!
Patient Q&A Section about nitro-bid
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.How long does it take for Nitro-Bid to work?
"The medication starts to work in less than an hour, but if you are having active chest pain, there are faster-acting forms of nitroglycerin, like the spray or sublingual tablet, that work within 5 minutes."
Answered by AI
What type of drug is Nitro-Bid?
"This medication is a nitrate, which is a type of drug that relaxes and widens blood vessels to ease blood flow to the heart. Nitrates are used to treat angina, which is chest pain that occurs when the heart muscle isn't getting enough blood."
Answered by AI
What is Nitro-Bid used for?
"Nitroglycerin ointment is used to prevent episodes of angina in people who have coronary artery disease."
Answered by AI
Does Nitro-Bid lower BP?
"Nitroglycerin can help relieve chest pain and lower blood pressure by dilating veins, but it doesn't work for everyone and only lasts for a short time."
Answered by AI