What is Nevanac
NepafenacThe Generic name of this drug
Treatment SummaryNepafenac is a prescription eye drop used to reduce pain and inflammation caused by cataract surgery. It is a type of non-steroidal anti-inflammatory drug (NSAID).
Nevanacis the brand name
Nevanac Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Nevanac
Nepafenac
2005
5
Approved as Treatment by the FDA
Nepafenac, also known as Nevanac, is approved by the FDA for 3 uses like Chronic Pain and Cataract Surgery .Chronic Pain
Helps manage Pain
Cataract Surgery
Helps manage Cataract Surgery
Inflammation
Helps manage Inflammation
Effectiveness
How Nevanac Affects PatientsWhen nepafenac ophthalmic suspension was given three times a day, small levels of nepafenac and amfenac were found in most patients two and three hours after taking the dose. On average, the highest level of nepafenac was 0.310 ng/ml, while the highest level of amfenac was 0.422 ng/ml.
How Nevanac works in the bodyNepafenac is a medication that is used to reduce inflammation in the cornea. It is a prodrug, meaning when it enters the body it converts into a more active form. This form, called amfenac, is an NSAID that stops the activity of two enzymes that cause inflammation.
When to interrupt dosage
The suggested amount of Nevanac is subject to the diagnosed affliction, including Inflammation, Cataract Surgery and Chronic Pain. The measure of dosage is contingent upon the technique of delivery (e.g. Suspension / drops or Ophthalmic) specified in the table beneath.Condition
Dosage
Administration
Inflammation
, 3.0 mg/mL, 1.0 mg/mL, 0.3 %, 0.1 %
Suspension / drops, Ophthalmic, , Suspension / drops - Ophthalmic, Suspension, Suspension - Ophthalmic
Cataract Surgery
, 3.0 mg/mL, 1.0 mg/mL, 0.3 %, 0.1 %
Suspension / drops, Ophthalmic, , Suspension / drops - Ophthalmic, Suspension, Suspension - Ophthalmic
Chronic Pain
, 3.0 mg/mL, 1.0 mg/mL, 0.3 %, 0.1 %
Suspension / drops, Ophthalmic, , Suspension / drops - Ophthalmic, Suspension, Suspension - Ophthalmic
Warnings
Nevanac ContraindicationsCondition
Risk Level
Notes
Toxoplasma Infections
Do Not Combine
Common Nevanac Drug Interactions
Drug Name
Risk Level
Description
Olsalazine
Minor
The risk or severity of nephrotoxicity can be increased when Nepafenac is combined with Olsalazine.
Valproic acid
Minor
The protein binding of Valproic acid can be decreased when combined with Nepafenac.
Acemetacin
Moderate
The risk or severity of adverse effects can be increased when Nepafenac is combined with Acemetacin.
Acetylsalicylic acid
Moderate
The therapeutic efficacy of Acetylsalicylic acid can be decreased when used in combination with Nepafenac.
Alclofenac
Moderate
The risk or severity of adverse effects can be increased when Nepafenac is combined with Alclofenac.
Nevanac Toxicity & Overdose RiskNon-steroidal anti-inflammatory drugs can increase the risk of bleeding in the eye when used before certain surgeries. This can lead to a build-up of blood in the eye, known as a hyphema.
Nevanac Novel Uses: Which Conditions Have a Clinical Trial Featuring Nevanac?
357 active trials are currently analyzing the efficacy of Nevanac in mitigating Inflammation, Chronic Pain and providing relief during Cataract Surgery.Condition
Clinical Trials
Trial Phases
Inflammation
171 Actively Recruiting
Phase 1, Phase 2, Not Applicable, Early Phase 1, Phase 3, Phase 4
Chronic Pain
172 Actively Recruiting
Phase 2, Phase 3, Not Applicable, Phase 1, Phase 4, Early Phase 1
Cataract Surgery
2 Actively Recruiting
Not Applicable, Phase 4
Nevanac Reviews: What are patients saying about Nevanac?
5Patient Review
3/14/2009 surgeons only recommend this as an anti-inflammatory. Unfortunately, it caused decreased vision and the sensation of something in my eye after my cataract surgery.
5Patient Review
7/24/2009 There's a bit of initial burning, but it's nothing compared to the relief it provides.
5Patient Review
10/12/2011 Nevanac was really helpful for me after cataract surgery. Whenever I felt any pain or discomfort in my eye, it would go away within minutes. My vision is now perfect.
4.3Patient Review
11/11/2009 These eye drops have been a godsend since my surgery.
3.3Patient Review
5/8/2015 Nevanac is a great medication, but the bottle design is very difficult to use. It's hard to get just one drop out, and you have to squeeze so hard that you might end up with several drops. This is especially difficult for seniors who are using this medication. Please help fix the bottle problem.
3.3Patient Review
5/17/2009 I had cataract surgery eight weeks ago and laser surgery two weeks ago. I was put on these drops to help with a post-operative infection and irritation, and so far they've been working well.
3.3Patient Review
4/9/2009 I took this before and after my surgery. I experienced zero pain, which was really amazing and unexpected.
3Patient Review
6/18/2013 The thickness of this cream makes it difficult to apply directly to the eye. It's also tough to get out of the bottle and takes a while to come out. I have arthritis in my fingers, which made it even more difficult to use. Despite all of that, it's been effective and my ophthalmologist has ordered me to continue using it every day.
3Patient Review
3/17/2020 The design of this bottle is very difficult to use, especially for those with arthritis or other conditions that cause weakness in the hands. It took me two weeks to get all the drops out of one bottle. I'm glad my pharmacist was able to sell me another, but I wonder if the manufacturer is happy that people are running out early because of poor design.
3Patient Review
3/16/2010 This treatment really helped me. I'm grateful for modern medicine.
3Patient Review
5/23/2010 I started taking this medication before my cataract surgery, along with vigamox. Now, I use Nevanac, Vigamox, and Durezol drops three times a day in my right eye post-op. It's going well so far, but I have been feeling nauseous after using the drops. I'm not sure if it's the Nevanac specifically or the combination of all three that's causing problems. If anyone else has experienced similar side effects from Nevanac, please let me know.
2.3Patient Review
7/15/2011 After a partial transplant and cataract surgery, I realized that this medication (which I later learned was an NSAID) caused severe stomach upset. By the time I discovered that this medication was the culprit, I was practically bedridden! It is extremely expensive!!
1.7Patient Review
3/4/2009Patient Q&A Section about nevanac
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.When do you use Nevanac eye drops?
"Use Nevanac once every 8 hours for three days leading up to cataract surgery. Surgery day is included, and you should use it for two weeks after the surgery as well."
Answered by AI
What is another name for Nevanac?
"The drug Nepafenac, sold under the brand name Nevanac, is a nonsteroidal anti-inflammatory drug (NSAID) that is usually only available as a prescription eye drop 0.1% solution (Nevanac) or 0.3% solution (Ilevro). It is used to treat pain and inflammation associated with cataract surgery."
Answered by AI
What are the side effects of Nevanac eye drops?
"The active ingredient in this medication may cause temporary stinging or burning in your eyes for 1-2 minutes when applied. Other possible side effects include eye redness,, headache,, dry or sticky feeling in the eye,, feeling like something is in your eye,, itching or watering of the eye,, increased sensitivity to light,, nausea."
Answered by AI