Mucomyst

Allergic Rhinitis, Corneal Diseases, Sinusitis + 9 more

Treatment

5 Active Studies for Mucomyst

What is Mucomyst

Acetylcysteine

The Generic name of this drug

Treatment Summary

Acetylcysteine is a medication used to break up mucus and treat acetaminophen overdose. It has also been studied for other conditions, but the results have been mixed. This drug was approved by the FDA in 1963.

Acetylcysteine

is the brand name

image of different drug pills on a surface

Mucomyst Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Acetylcysteine

Acetylcysteine

1989

41

Effectiveness

How Mucomyst Affects Patients

Acetylcysteine is used to treat mucus buildup and acetaminophen poisonings. It is usually taken 1-8 hours apart depending on the method of administration. Its side effects are generally not severe, but patients should be warned of the possibility of an allergic reaction or stomach bleeding. Acetylcysteine can have a strong unpleasant taste, so patients may need to mix it with soda for flavor.

How Mucomyst works in the body

Acetylcysteine works in various ways to reduce mucous. It can break down the bonds that form thick mucous, reducing its viscosity. It also works to reduce the total amount of mucous produced. Additionally, it acts as an antioxidant, reducing the amount of molecules in the body that can cause cell damage. In cases of acetaminophen overdoses, acetylcysteine also helps protect cells by providing cysteine for glutathione production or by directly binding to toxic molecules that can cause cellular damage.

When to interrupt dosage

The recommended serving of Mucomyst is contingent upon the diagnosed condition, including Allergic Rhinitis, Airway secretion clearance therapy and Keratopathy. The quantity of dosage fluctuates as per the technique of delivery (e.g. Inhalant or Injection, solution) featured in the table beneath.

Condition

Dosage

Administration

Corneal Diseases

, 100.0 mg/mL, 200.0 mg/mL, 600.0 mg/mL, 500.0 mg, 2500.0 mg, 600.0 mg, 50.0 mg, 200.0 mg

Oral; Respiratory (inhalation), , Solution - Oral; Respiratory (inhalation), Solution, Respiratory (inhalation), Inhalant - Respiratory (inhalation), Inhalant, Injection, Intravenous, Injection - Intravenous, Injection, solution - Intravenous, Injection, solution, Solution - Intravenous; Oral; Respiratory (inhalation), Liquid, Liquid - Intravenous, Tablet, effervescent, Oral, Tablet, effervescent - Oral, Inhalant - Oral; Respiratory (inhalation), Tablet - Oral, Capsule, Capsule - Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, Liquid - Intravenous; Oral; Respiratory (inhalation), Intravenous; Oral; Respiratory (inhalation)

Sinusitis

, 100.0 mg/mL, 200.0 mg/mL, 600.0 mg/mL, 500.0 mg, 2500.0 mg, 600.0 mg, 50.0 mg, 200.0 mg

Oral; Respiratory (inhalation), , Solution - Oral; Respiratory (inhalation), Solution, Respiratory (inhalation), Inhalant - Respiratory (inhalation), Inhalant, Injection, Intravenous, Injection - Intravenous, Injection, solution - Intravenous, Injection, solution, Solution - Intravenous; Oral; Respiratory (inhalation), Liquid, Liquid - Intravenous, Tablet, effervescent, Oral, Tablet, effervescent - Oral, Inhalant - Oral; Respiratory (inhalation), Tablet - Oral, Capsule, Capsule - Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, Liquid - Intravenous; Oral; Respiratory (inhalation), Intravenous; Oral; Respiratory (inhalation)

Rhinitis

, 100.0 mg/mL, 200.0 mg/mL, 600.0 mg/mL, 500.0 mg, 2500.0 mg, 600.0 mg, 50.0 mg, 200.0 mg

Oral; Respiratory (inhalation), , Solution - Oral; Respiratory (inhalation), Solution, Respiratory (inhalation), Inhalant - Respiratory (inhalation), Inhalant, Injection, Intravenous, Injection - Intravenous, Injection, solution - Intravenous, Injection, solution, Solution - Intravenous; Oral; Respiratory (inhalation), Liquid, Liquid - Intravenous, Tablet, effervescent, Oral, Tablet, effervescent - Oral, Inhalant - Oral; Respiratory (inhalation), Tablet - Oral, Capsule, Capsule - Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, Liquid - Intravenous; Oral; Respiratory (inhalation), Intravenous; Oral; Respiratory (inhalation)

Rhinitis, Allergic

, 100.0 mg/mL, 200.0 mg/mL, 600.0 mg/mL, 500.0 mg, 2500.0 mg, 600.0 mg, 50.0 mg, 200.0 mg

Oral; Respiratory (inhalation), , Solution - Oral; Respiratory (inhalation), Solution, Respiratory (inhalation), Inhalant - Respiratory (inhalation), Inhalant, Injection, Intravenous, Injection - Intravenous, Injection, solution - Intravenous, Injection, solution, Solution - Intravenous; Oral; Respiratory (inhalation), Liquid, Liquid - Intravenous, Tablet, effervescent, Oral, Tablet, effervescent - Oral, Inhalant - Oral; Respiratory (inhalation), Tablet - Oral, Capsule, Capsule - Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, Liquid - Intravenous; Oral; Respiratory (inhalation), Intravenous; Oral; Respiratory (inhalation)

Corneal Diseases

, 100.0 mg/mL, 200.0 mg/mL, 600.0 mg/mL, 500.0 mg, 2500.0 mg, 600.0 mg, 50.0 mg, 200.0 mg

Oral; Respiratory (inhalation), , Solution - Oral; Respiratory (inhalation), Solution, Respiratory (inhalation), Inhalant - Respiratory (inhalation), Inhalant, Injection, Intravenous, Injection - Intravenous, Injection, solution - Intravenous, Injection, solution, Solution - Intravenous; Oral; Respiratory (inhalation), Liquid, Liquid - Intravenous, Tablet, effervescent, Oral, Tablet, effervescent - Oral, Inhalant - Oral; Respiratory (inhalation), Tablet - Oral, Capsule, Capsule - Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, Liquid - Intravenous; Oral; Respiratory (inhalation), Intravenous; Oral; Respiratory (inhalation)

Rhinitis, Vasomotor

, 100.0 mg/mL, 200.0 mg/mL, 600.0 mg/mL, 500.0 mg, 2500.0 mg, 600.0 mg, 50.0 mg, 200.0 mg

Oral; Respiratory (inhalation), , Solution - Oral; Respiratory (inhalation), Solution, Respiratory (inhalation), Inhalant - Respiratory (inhalation), Inhalant, Injection, Intravenous, Injection - Intravenous, Injection, solution - Intravenous, Injection, solution, Solution - Intravenous; Oral; Respiratory (inhalation), Liquid, Liquid - Intravenous, Tablet, effervescent, Oral, Tablet, effervescent - Oral, Inhalant - Oral; Respiratory (inhalation), Tablet - Oral, Capsule, Capsule - Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, Liquid - Intravenous; Oral; Respiratory (inhalation), Intravenous; Oral; Respiratory (inhalation)

Rhinitis

, 100.0 mg/mL, 200.0 mg/mL, 600.0 mg/mL, 500.0 mg, 2500.0 mg, 600.0 mg, 50.0 mg, 200.0 mg

Oral; Respiratory (inhalation), , Solution - Oral; Respiratory (inhalation), Solution, Respiratory (inhalation), Inhalant - Respiratory (inhalation), Inhalant, Injection, Intravenous, Injection - Intravenous, Injection, solution - Intravenous, Injection, solution, Solution - Intravenous; Oral; Respiratory (inhalation), Liquid, Liquid - Intravenous, Tablet, effervescent, Oral, Tablet, effervescent - Oral, Inhalant - Oral; Respiratory (inhalation), Tablet - Oral, Capsule, Capsule - Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, Liquid - Intravenous; Oral; Respiratory (inhalation), Intravenous; Oral; Respiratory (inhalation)

acetaminophen

, 100.0 mg/mL, 200.0 mg/mL, 600.0 mg/mL, 500.0 mg, 2500.0 mg, 600.0 mg, 50.0 mg, 200.0 mg

Oral; Respiratory (inhalation), , Solution - Oral; Respiratory (inhalation), Solution, Respiratory (inhalation), Inhalant - Respiratory (inhalation), Inhalant, Injection, Intravenous, Injection - Intravenous, Injection, solution - Intravenous, Injection, solution, Solution - Intravenous; Oral; Respiratory (inhalation), Liquid, Liquid - Intravenous, Tablet, effervescent, Oral, Tablet, effervescent - Oral, Inhalant - Oral; Respiratory (inhalation), Tablet - Oral, Capsule, Capsule - Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, Liquid - Intravenous; Oral; Respiratory (inhalation), Intravenous; Oral; Respiratory (inhalation)

Airway secretion clearance therapy

, 100.0 mg/mL, 200.0 mg/mL, 600.0 mg/mL, 500.0 mg, 2500.0 mg, 600.0 mg, 50.0 mg, 200.0 mg

Oral; Respiratory (inhalation), , Solution - Oral; Respiratory (inhalation), Solution, Respiratory (inhalation), Inhalant - Respiratory (inhalation), Inhalant, Injection, Intravenous, Injection - Intravenous, Injection, solution - Intravenous, Injection, solution, Solution - Intravenous; Oral; Respiratory (inhalation), Liquid, Liquid - Intravenous, Tablet, effervescent, Oral, Tablet, effervescent - Oral, Inhalant - Oral; Respiratory (inhalation), Tablet - Oral, Capsule, Capsule - Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, Liquid - Intravenous; Oral; Respiratory (inhalation), Intravenous; Oral; Respiratory (inhalation)

Corneal Ulcer

, 100.0 mg/mL, 200.0 mg/mL, 600.0 mg/mL, 500.0 mg, 2500.0 mg, 600.0 mg, 50.0 mg, 200.0 mg

Oral; Respiratory (inhalation), , Solution - Oral; Respiratory (inhalation), Solution, Respiratory (inhalation), Inhalant - Respiratory (inhalation), Inhalant, Injection, Intravenous, Injection - Intravenous, Injection, solution - Intravenous, Injection, solution, Solution - Intravenous; Oral; Respiratory (inhalation), Liquid, Liquid - Intravenous, Tablet, effervescent, Oral, Tablet, effervescent - Oral, Inhalant - Oral; Respiratory (inhalation), Tablet - Oral, Capsule, Capsule - Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, Liquid - Intravenous; Oral; Respiratory (inhalation), Intravenous; Oral; Respiratory (inhalation)

Allergic Rhinitis

, 100.0 mg/mL, 200.0 mg/mL, 600.0 mg/mL, 500.0 mg, 2500.0 mg, 600.0 mg, 50.0 mg, 200.0 mg

Oral; Respiratory (inhalation), , Solution - Oral; Respiratory (inhalation), Solution, Respiratory (inhalation), Inhalant - Respiratory (inhalation), Inhalant, Injection, Intravenous, Injection - Intravenous, Injection, solution - Intravenous, Injection, solution, Solution - Intravenous; Oral; Respiratory (inhalation), Liquid, Liquid - Intravenous, Tablet, effervescent, Oral, Tablet, effervescent - Oral, Inhalant - Oral; Respiratory (inhalation), Tablet - Oral, Capsule, Capsule - Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, Liquid - Intravenous; Oral; Respiratory (inhalation), Intravenous; Oral; Respiratory (inhalation)

Rhinitis

, 100.0 mg/mL, 200.0 mg/mL, 600.0 mg/mL, 500.0 mg, 2500.0 mg, 600.0 mg, 50.0 mg, 200.0 mg

Oral; Respiratory (inhalation), , Solution - Oral; Respiratory (inhalation), Solution, Respiratory (inhalation), Inhalant - Respiratory (inhalation), Inhalant, Injection, Intravenous, Injection - Intravenous, Injection, solution - Intravenous, Injection, solution, Solution - Intravenous; Oral; Respiratory (inhalation), Liquid, Liquid - Intravenous, Tablet, effervescent, Oral, Tablet, effervescent - Oral, Inhalant - Oral; Respiratory (inhalation), Tablet - Oral, Capsule, Capsule - Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, Liquid - Intravenous; Oral; Respiratory (inhalation), Intravenous; Oral; Respiratory (inhalation)

Warnings

Mucomyst Contraindications

Condition

Risk Level

Notes

Severe Hypersensitivity Reactions

Do Not Combine

Acetylcysteine may interact with Pulse Frequency

There are 20 known major drug interactions with Mucomyst.

Common Mucomyst Drug Interactions

Drug Name

Risk Level

Description

Revefenacin

Major

Acetylcysteine may decrease the excretion rate of Revefenacin which could result in a higher serum level.

Ambrisentan

Minor

The excretion of Ambrisentan can be decreased when combined with Acetylcysteine.

Asunaprevir

Minor

The excretion of Asunaprevir can be decreased when combined with Acetylcysteine.

Atorvastatin

Minor

The excretion of Atorvastatin can be decreased when combined with Acetylcysteine.

Atrasentan

Minor

The excretion of Atrasentan can be decreased when combined with Acetylcysteine.

Mucomyst Toxicity & Overdose Risk

Overdosing on Acetylcysteine may cause vomiting, nausea, difficulty breathing, swelling around the eyes, and low blood pressure. Treatment should focus on relieving symptoms and providing supportive care. Dialysis may also be used to remove some of the drug from the bloodstream as it is partly bound to proteins.

image of a doctor in a lab doing drug, clinical research

Mucomyst Novel Uses: Which Conditions Have a Clinical Trial Featuring Mucomyst?

There are 48 active clinical trials investigating the potential of Mucomyst in providing relief from Sinusitis, acute Rhinitis and Keratopathy.

Condition

Clinical Trials

Trial Phases

acetaminophen

0 Actively Recruiting

Corneal Ulcer

0 Actively Recruiting

Corneal Diseases

2 Actively Recruiting

Not Applicable

Corneal Diseases

0 Actively Recruiting

Rhinitis

0 Actively Recruiting

Rhinitis, Vasomotor

1 Actively Recruiting

Not Applicable

Sinusitis

2 Actively Recruiting

Not Applicable

Airway secretion clearance therapy

0 Actively Recruiting

Rhinitis, Allergic

0 Actively Recruiting

Allergic Rhinitis

0 Actively Recruiting

Rhinitis

0 Actively Recruiting

Rhinitis

0 Actively Recruiting

Mucomyst Reviews: What are patients saying about Mucomyst?

5

Patient Review

6/29/2008

Mucomyst for Prevention of Kidney Damage due to Contrast Media

I was also given mucomyst to prevent kidney damage from the use of lasix. This medicine was successful and my creatinine levels went back to normal.

4.7

Patient Review

2/19/2014

Mucomyst for Bronchitis

My doctor prescribed this to me in order to prevent kidney damage from the dyes in my medication, but I also had bronchitis at the time. It really helped shorten the duration of my illness.

4

Patient Review

1/25/2014

Mucomyst for An Increase in the Thickness of Lung Secretions

It was tough to find a pharmacy that could get this, and even then my insurance company made things more difficult with their pre-authorization requirement (which has never been necessary for any other prescriptions I've gotten).

2.7

Patient Review

11/24/2009

Mucomyst for Prevention of Kidney Damage due to Contrast Media

The FDA hasn't yet recognized this treatment for kidney problems related to IV contrast injections.

2

Patient Review

10/23/2013

Mucomyst for Prevention of Kidney Damage due to Contrast Media

I was very disappointed with both the pharmacy and drug company. The doctor ordered 20 ml, but we were forced to purchase 120 ml at a cost of $671. I believe this is stealing or fraud.

2

Patient Review

11/19/2009

Mucomyst for An Increase in the Thickness of Lung Secretions

The after taste of this medication is incredibly unpleasant and made me feel nauseous.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about mucomyst

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What does Mucomyst smell like?

"The acetylcysteine molecule has sulfur, which can remind people of the smell of rotten eggs. This is normal and does not mean that the medication itself is bad."

Answered by AI

What is Mucomyst used for?

"The medication acetylcysteine is used to help break up mucus in the airways of people who have certain lung diseases. This helps the person clear the mucus from their lungs so that they can breathe more easily."

Answered by AI

What type of drug is Mucomyst?

"The drug Mucomyst, used to treat the symptoms of pulmonary disease and for diagnostic bronchoscopy, is available in generic form under the name Acetylcysteine Solution. It may be used alone or with other medications."

Answered by AI

Is mucinex and Mucomyst the same?

"The similarity in appearance and sound between the drug names Mucomyst and Mucinex is due to the fact that both names start with the same three letters. Even though the last letters of each name are quite different, if they are not written clearly, it may be difficult to tell them apart."

Answered by AI

Clinical Trials for Mucomyst

Image of Cedars-Sinai Medical Center Otolaryngology Clinics in Los Angeles, United States.

Lavender Aromatherapy for Anxiety and Pain During Otolaryngologic Procedures

18+
All Sexes
Los Angeles, CA

The purpose of this study is to evaluate the efficacy of lavender aromatherapy in adult patients undergoing awake otolaryngologic procedures in the outpatient clinic setting. The main questions it aims to answer are: * Does lavender aromatherapy help reduce anxiety and/or pain, and improve patient comfort during awake otolaryngologic procedures in the clinic? * Do patients subjectively find aromatherapy relaxing and/or beneficial during the procedure? Researchers will compare lavender aromatherapy to placebo (an odorless liquid) to see if lavender aromatherapy helps improve patient comfort during their awake procedure Participants will: * Have their scheduled procedure performed with lavender aromatherapy or placebo during the duration of the procedure * Take a short, less than 1 minute questionnaire both before and after the procedure, describing their levels of anxiety, pain and subjective impressions of the aromatherapy

Recruiting
Paid Trial

Cedars-Sinai Medical Center Otolaryngology Clinics

Ankona Ghosh, MD

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