Microgestin 1.5/30

Endometriosis, Low Testosterone, Osteoporosis + 16 more
Treatment
20 Active Studies for Microgestin 1.5/30

What is Microgestin 1.5/30

NorethisteroneThe Generic name of this drug
Treatment SummaryNorethisterone, also known as norethindrone, is a type of hormone medication used to treat irregular periods and endometriosis. It was first used in 1951 and was approved for use as an oral contraceptive in 1962. Norethisterone is a synthetic form of progestin, which is a type of hormone similar to the natural hormone progesterone. It is a second-generation progestin, which means it is more potent than other forms of progestin. It can be taken on its own or combined with other hormone medications for contraception or hormone replacement therapy.
Neconis the brand name
image of different drug pills on a surface
Microgestin 1.5/30 Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Necon
Norethisterone
1967
347

Effectiveness

How Microgestin 1.5/30 Affects PatientsNorethisterone is a pill form of the hormone progesterone which is used for birth control or to treat other hormone-related issues such as menopause and endometriosis. It works similarly to the progesterone produced by the body but is more powerful and affects the pelvic area, as well as the hormones that control ovulation. While using this type of birth control has been linked to a slightly increased risk of breast cancer, patients should be informed of this risk and should regularly do self-examinations to check for any lumps.
How Microgestin 1.5/30 works in the bodyNorethisterone works by binding to progesterone receptors in various parts of the body, including the reproductive tract, breast, pituitary gland, hypothalamus, and central nervous system. It thickens cervical mucus to prevent sperm from entering the uterus and makes the endometrium unsuitable for implantation. It also suppresses the hormones FSH and LH, preventing ovulation and corpus luteum development. When used in menopausal women as part of hormone replacement therapy, norethisterone helps protect against endometrial hyperplasia and lower the risk of endometrial cancer. Although it has a low

When to interrupt dosage

The endorsed dosage of Microgestin 1.5/30 is contingent upon the confirmed affliction, for example Atrophic, Fracture and Hormone Replacement Therapy. The measure of dosage can be found in the table beneath, contingent upon the mode of administration (e.g. Oral or Tablet).
Condition
Dosage
Administration
Atrophic
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Hot flashes
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Hormone Replacement Therapy
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
female castration
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Low Testosterone
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
hypoestrogenism
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Therapeutic procedure
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Fracture
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Ovarian Failure
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Postmenopausal Osteoporosis
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Vasomotor System
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Oral Contraceptives
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Hormonal Contraception
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Estrogen Deprivation Symptoms
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Menopause
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Endometriosis
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Birth Control
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Osteoporosis
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Endometriosis
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical

Warnings

Microgestin 1.5/30 Contraindications
Condition
Risk Level
Notes
active liver disease
Do Not Combine
Thrombophilia
Do Not Combine
Vaginal Hemorrhage
Do Not Combine
Malignant Neoplasms
Do Not Combine
Benign hepatic neoplasm
Do Not Combine
Breast Cancer
Do Not Combine
Thromboembolism
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Norethisterone may interact with Pulse Frequency
There are 20 known major drug interactions with Microgestin 1.5/30.
Common Microgestin 1.5/30 Drug Interactions
Drug Name
Risk Level
Description
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Norethisterone.
Axitinib
Major
The metabolism of Axitinib can be decreased when combined with Norethisterone.
Cabazitaxel
Major
The metabolism of Cabazitaxel can be decreased when combined with Norethisterone.
Clomipramine
Major
The metabolism of Clomipramine can be increased when combined with Norethisterone.
Copanlisib
Major
The metabolism of Copanlisib can be decreased when combined with Norethisterone.
Microgestin 1.5/30 Toxicity & Overdose RiskThe toxic dose of oral contraceptives in mice is 6g/kg and in women is 42mg/kg. Even if a child takes an overdose of oral contraceptives, there have been no reports of serious harm. Some of the possible symptoms of overdosing on oral contraceptives are nausea and vomiting.

Microgestin 1.5/30 Novel Uses: Which Conditions Have a Clinical Trial Featuring Microgestin 1.5/30?

160 active clinical trials are currently assessing the potential of Microgestin 1.5/30 to provide Birth Control, Atrophic Uterine Conditions and Low Testosterone treatments.
Condition
Clinical Trials
Trial Phases
Endometriosis
32 Actively Recruiting
Phase 3, Not Applicable, Early Phase 1, Phase 2, Phase 4, Phase 1
Osteoporosis
40 Actively Recruiting
Phase 1, Phase 2, Not Applicable, Early Phase 1, Phase 4, Phase 3
Estrogen Deprivation Symptoms
0 Actively Recruiting
Oral Contraceptives
2 Actively Recruiting
Not Applicable
Therapeutic procedure
0 Actively Recruiting
Menopause
0 Actively Recruiting
Hormone Replacement Therapy
0 Actively Recruiting
Atrophic
6 Actively Recruiting
Phase 2, Phase 4, Not Applicable
Low Testosterone
15 Actively Recruiting
Phase 1, Phase 4, Phase 2, Not Applicable
Hot flashes
22 Actively Recruiting
Phase 2, Not Applicable, Phase 1, Phase 4, Early Phase 1
Postmenopausal Osteoporosis
3 Actively Recruiting
Not Applicable, Phase 4
Birth Control
31 Actively Recruiting
Not Applicable, Phase 3, Phase 4, Early Phase 1
Fracture
0 Actively Recruiting
female castration
0 Actively Recruiting
hypoestrogenism
2 Actively Recruiting
Phase 4
Vasomotor System
0 Actively Recruiting
Endometriosis
1 Actively Recruiting
Phase 4
Ovarian Failure
2 Actively Recruiting
Not Applicable, Phase 1
Hormonal Contraception
0 Actively Recruiting

Microgestin 1.5/30 Reviews: What are patients saying about Microgestin 1.5/30?

5Patient Review
8/16/2013
Microgestin 1.5/30 for Birth Control
I've tried a few different birth controls now, and this one is by far my favorite. I didn't have any issues with nausea like some people do, and it really helped to regulate my hormones.
5Patient Review
3/29/2018
Microgestin 1.5/30 for Birth Control
I switched to this pill two months ago and it has been a vast improvement. The first pill I was on caused terrible prolonged bleeding, but I have experienced none of those side effects on this pill. It also appears to be effective, so all in all I'm very pleased with the switch.
4.7Patient Review
5/25/2012
Microgestin 1.5/30 for Birth Control
Microgestin has been a much better experience for me than Reclipsen. My period cramps have all but disappeared and it's helped regulate my cycle well. The only downside is that I sometimes feel nauseous and my sex drive has decreased slightly. All things considered, this birth control gets an A from me.
4.7Patient Review
10/24/2010
Microgestin 1.5/30 for Birth Control
Though this medicine has effectively prevented pregnancy, it's come with the cost of irregular periods. Some months I'll bleed the entire week, and other times there's no bleeding at all. Additionally, if I miss even one iron pill throughout the month, my period will completely stop. It's a frustrating trade-off, but ultimately this medication does what it intends to do.
4Patient Review
2/4/2011
Microgestin 1.5/30 for Birth Control
I switched from yaz to this pill because yaz stopped my periods completely. Been on this pill 7 months and already my period is shorter each month and is now down to two days. My obgyn put me on it guaranteeing my period would be normal. At this point I think I need to switch to something else.
3.7Patient Review
3/3/2008
Microgestin 1.5/30 for Birth Control
3.7Patient Review
12/27/2009
Microgestin 1.5/30 for Birth Control
I started experiencing the negative side effects of this medication almost immediately. It's been three weeks and I haven't seen any improvement.
3Patient Review
8/9/2013
Microgestin 1.5/30 for Absence of Menstrual Periods
I do not recommend this pill. Every time I started a new pack, I would get nauseous and faint. I had migraines with aura and a lot of break through bleeding even though I was on it for a year.. Now I've been off the pill for months and am unable to get my period because my hormones are so messed up.
2.3Patient Review
6/8/2011
Microgestin 1.5/30 for Birth Control
Going on this birth control made me unrecognizable to myself- in the worst ways possible. I was constantly angry, anxious, stressed, and depressed. Additionally, it killed my sex drive to a point where I was content with never having sex again. Do not make the same mistake I did.
2.3Patient Review
9/1/2021
Microgestin 1.5/30 for Painful Periods
I took this to stop my periods because I had endometriosis really bad and I was on it for basically 6 months. It worked great until it gave me a stroke.
1.7Patient Review
8/3/2008
Microgestin 1.5/30 for Birth Control
My potassium level spiked after taking this medication, which was very concerning.
1.3Patient Review
3/8/2017
Microgestin 1.5/30 for Birth Control
Overall, this has been a terrible experience with birth control. I've gained weight, my acne is worse, and my mood has taken a significant hit since starting to use this pill.
1Patient Review
11/23/2009
Microgestin 1.5/30 for Birth Control
I'm really confused about this medication. The information says it's for reducing menopause symptoms, but I was prescribed this as a birth control at age 22. Is it also used as birth control? If not, can taking this have negative consequences if I'm not actually in menopause?
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about microgestin 1.5/30

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What kind of birth control is Microgestin 1.5 30?

"The microgestin 1.5/30 is a birth control pill that contains two types of hormones, ethinyl estradiol and norethindrone. When taken properly, it prevents pregnancy by stopping a woman's egg from fully developing each month."

Answered by AI

What are the side effects of Microgestin Fe 1.5 30?

"The following side effects may occur when taking this medication: nausea, vomiting, headache, bloating, breast tenderness, swelling of the ankles/feet (fluid retention), or weight change. You may also experience vaginal bleeding between periods (spotting) or missed/irregular periods, especially during the first few months of use."

Answered by AI

Does Microgestin 1.5 30 stop your period?

"Although not common, some women may notice irregular periods or spotting during the first few months of using Microgestin 1.5/30. However, these symptoms should go away as the body adjusts to the birth control medication."

Answered by AI

Is Microgestin 1.5 30 A combination pill?

"The Microgestin 1.5/30 pill is a combination of ethinyl estradiol and norethindrone, which are female hormones that prevent ovulation."

Answered by AI

Clinical Trials for Microgestin 1.5/30

Have you considered Microgestin 1.5/30 clinical trials? We made a collection of clinical trials featuring Microgestin 1.5/30, we think they might fit your search criteria.
Have you considered Microgestin 1.5/30 clinical trials? We made a collection of clinical trials featuring Microgestin 1.5/30, we think they might fit your search criteria.
Have you considered Microgestin 1.5/30 clinical trials? We made a collection of clinical trials featuring Microgestin 1.5/30, we think they might fit your search criteria.