Iodotope

Hyperthyroidism, Thyroid Neoplasms, Malignant Neoplasms + 1 more
Treatment
8 FDA approvals
2 Active Studies for Iodotope

What is Iodotope

Iodide I-131The Generic name of this drug
Treatment SummaryIodide I-131 (also known as Sodium iodide I-131) is a radioactive drug used to treat thyroid cancer and thyroid diseases. It works by emitting radiation that kills cells in the targeted area. The thyroid gland naturally absorbs iodine in the body, so this drug is used to target cancerous cells. Iodide I-131 is used to treat hyperthyroidism, thyroid carcinomas, and to perform a radioactive iodide (RAI) uptake test to evaluate thyroid function. It can also be used to reduce symptoms of advanced thyroid cancer.
Iodotopeis the brand name
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Iodotope Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Iodotope
Iodide I-131
1957
11

Approved as Treatment by the FDA

Iodide I-131, also known as Iodotope, is approved by the FDA for 8 uses including Metastatic Medullary Thyroid Cancer and Hyperthyroidism .
Metastatic Medullary Thyroid Cancer
Hyperthyroidism
Radioactive iodine uptake test
Thyroid Carcinoma
Hyperthyroidism
Thyroid Neoplasms
Malignant Neoplasms
Thyroid Gland

Effectiveness

How Iodotope Affects PatientsSodium iodide I-131 is used to treat thyroid-related issues. The medication works by sending radiation to the thyroid tissue, which damages molecules and causes them to break apart. The radiation is made up of 90% beta radiation and 10% gamma radiation.
How Iodotope works in the bodySodium iodide I-131 is a medication taken by mouth. Once ingested, it is absorbed into the body and moves to the thyroid gland. It is then converted to iodine and emits beta radiation, which destroys thyroid tissue.

When to interrupt dosage

The suggested measure of Iodotope is contingent upon the diagnosed disorder, including Thyroid Carcinoma, radioactive iodide uptake test and Thyroid Gland. The dosage fluctuates as per the method of administration specified in the table beneath.
Condition
Dosage
Administration
Thyroid Neoplasms
5.0 mCi/mL, , 25.0 mCi/mL, 1.0 mCi/mL, 500.0 mCi, 100.0 mCi, 3500.0 mCi/mL, 200.0 mCi, 130.0 mCi, 1000.0 mCi
, Oral, Solution, Solution - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Capsule, Capsule - Oral, Solution, concentrate, Solution, concentrate - Oral, Kit - Oral, Kit
Thyroid Gland
5.0 mCi/mL, , 25.0 mCi/mL, 1.0 mCi/mL, 500.0 mCi, 100.0 mCi, 3500.0 mCi/mL, 200.0 mCi, 130.0 mCi, 1000.0 mCi
, Oral, Solution, Solution - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Capsule, Capsule - Oral, Solution, concentrate, Solution, concentrate - Oral, Kit - Oral, Kit
Hyperthyroidism
5.0 mCi/mL, , 25.0 mCi/mL, 1.0 mCi/mL, 500.0 mCi, 100.0 mCi, 3500.0 mCi/mL, 200.0 mCi, 130.0 mCi, 1000.0 mCi
, Oral, Solution, Solution - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Capsule, Capsule - Oral, Solution, concentrate, Solution, concentrate - Oral, Kit - Oral, Kit
Malignant Neoplasms
5.0 mCi/mL, , 25.0 mCi/mL, 1.0 mCi/mL, 500.0 mCi, 100.0 mCi, 3500.0 mCi/mL, 200.0 mCi, 130.0 mCi, 1000.0 mCi
, Oral, Solution, Solution - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Capsule, Capsule - Oral, Solution, concentrate, Solution, concentrate - Oral, Kit - Oral, Kit

Warnings

Iodotope has two known contraindications, so it should not be used for any of the circumstances given in the subsequent table.Iodotope Contraindications
Condition
Risk Level
Notes
Hypothyroidism
Do Not Combine
Gastroenteritis
Do Not Combine
Common Iodotope Drug Interactions
Drug Name
Risk Level
Description
Iodotope Toxicity & Overdose RiskSome of the side effects associated with sodium iodide I-131 treatment include swelling, inflammation of the salivary and tear glands, rash, hives, and thyroid problems. In cases of malignant disease, radiation sickness, anemia, cancer, and damage to the pulmonary system have been reported.
image of a doctor in a lab doing drug, clinical research

Iodotope Novel Uses: Which Conditions Have a Clinical Trial Featuring Iodotope?

Ten active trials are investigating the potential of Iodotope for use in radioactive iodide uptake testing, combatting Malignant Neoplasms, and treating Thyroid Carcinoma.
Condition
Clinical Trials
Trial Phases
Malignant Neoplasms
2 Actively Recruiting
Phase 2
Hyperthyroidism
0 Actively Recruiting
Thyroid Neoplasms
0 Actively Recruiting
Thyroid Gland
0 Actively Recruiting

Iodotope Reviews: What are patients saying about Iodotope?

5Patient Review
11/27/2012
Iodotope for Underactive Thyroid
I'm not sure if it's the medication or something else, but I've been feeling really nauseous lately. I called the nurse and she wasn't able to give me a clear answer. Has anyone else experienced this side effect?
5Patient Review
1/15/2013
Iodotope for Underactive Thyroid
I was really surprised to learn that if you don't take your thyroid medication, it can be fatal. I had no idea.
5Patient Review
5/31/2012
Iodotope for Underactive Thyroid
I've been treating my hashimoto's with this medication for five years now, and it's done wonders. I originally started on 50 mcg, but over time my dosage has increased to 88 mcg (with 100 mcg being too high). It would be nice if there was a 6 mcg dose available for people like me who fall in between the standard doses, since I only weigh 118 lb.
5Patient Review
9/7/2012
Iodotope for Underactive Thyroid
I've been on this medication since 2008 and I haven't seen my doctor monitor it since. In that time, I've had major mood swings, depression, weight gain, worsening seborrheic dermatitis, and zero energy. I need to either see a new doctor or get put on a different medication.
5Patient Review
4/18/2013
Iodotope for Underactive Thyroid
I haven't had any issues with this medication, as long as I take it as prescribed (on an empty stomach and with a full glass of water at least 30 minutes before eating).
View All Reviews
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Patient Q&A Section about iodotope

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How is sodium iodide 131 stored?

"Sodium iodide I 131 diagnostic capsules should be stored at controlled room temperature 68-77°F (20-25°C)."

Answered by AI

How does sodium iodide treat hyperthyroidism?

"This medication is mostly absorbed by the thyroid gland. In the treatment of an overactive thyroid gland, the radioactive iodine damages the thyroid gland to reduce its activity back to normal."

Answered by AI

What is Iodotope?

"Iodotope Sodium iodide I 131 can be used to treat hyperthyroidism and certain types of thyroid cancer by being taken up mainly by the thyroid gland."

Answered by AI

What is sodium iodine used for?

"Sodium iodide is a supplement used to prevent or treat iodine deficiency. Iodine is a mineral needed for the body to grow and stay healthy. Without enough iodine, the thyroid gland cannot function properly."

Answered by AI

Clinical Trials for Iodotope

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