What is Inderal La
PropranololThe Generic name of this drug
Treatment SummaryPropranolol is a medication used to treat high blood pressure. It is a combination of two enantiomers, with the S(-)-enantiomer having 100 times the binding affinity for beta adrenergic receptors. Propranolol has been approved by the FDA since 1967 and is used to treat a number of other conditions.
Inderalis the brand name
Inderal La Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Inderal
Propranolol
1967
471
Approved as Treatment by the FDA
Propranolol, also known as Inderal, is approved by the FDA for 3 uses including Tremor, Essential and Hypertensive disease .Tremor, Essential
Helps manage Tremor, Essential
Hypertensive disease
Used to treat High Blood Pressure (Hypertension) in combination with Hydrochlorothiazide
Obstructive Hypertrophic Cardiomyopathy
Effectiveness
How Inderal La Affects PatientsPropranolol is a drug used to treat high blood pressure. It can be taken in one or two doses each day and its effects last long. If someone stops taking propranolol suddenly, they may experience chest pain or heart attacks.
How Inderal La works in the bodyPropranolol blocks certain receptors in the body, resulting in decreased blood vessel growth and increased cell death. It also reduces the levels of hormones that regulate blood pressure.
When to interrupt dosage
The measure of Inderal La is contingent upon the identified affliction, including Catecholamines, Hypertensive illness and Hemangiomas. The amount of dosage is contingent upon the method of delivery (e.g. Solution - Oral or Capsule, extended release - Oral) as specified in the table below.Condition
Dosage
Administration
Pheochromocytomas
, 120.0 mg, 60.0 mg, 2.0 mg/mg, 4.0 mg/mg, 4.28 mg/mL, 1.0 mg/mL, 3.75 mg/mL, 20.0 mg/mL, 160.0 mg, 80.0 mg, 40.0 mg, 20.0 mg, 10.0 mg, 50.0 mg, 0.1 mg, 40.0 mg/mL
Solution - Oral, Capsule, extended release - Oral, Tablet - Oral, Liquid - Intravenous, Tablet, , Oral, Capsule, extended release, Injection, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Solution - Intravenous, Injection - Intravenous, Solution, Intravenous, Liquid, Injection, solution, Injection, solution - Intravenous
Gastroesophageal variceal hemorrhage prophylaxis
, 120.0 mg, 60.0 mg, 2.0 mg/mg, 4.0 mg/mg, 4.28 mg/mL, 1.0 mg/mL, 3.75 mg/mL, 20.0 mg/mL, 160.0 mg, 80.0 mg, 40.0 mg, 20.0 mg, 10.0 mg, 50.0 mg, 0.1 mg, 40.0 mg/mL
Solution - Oral, Capsule, extended release - Oral, Tablet - Oral, Liquid - Intravenous, Tablet, , Oral, Capsule, extended release, Injection, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Solution - Intravenous, Injection - Intravenous, Solution, Intravenous, Liquid, Injection, solution, Injection, solution - Intravenous
Myocardial Infarction
, 120.0 mg, 60.0 mg, 2.0 mg/mg, 4.0 mg/mg, 4.28 mg/mL, 1.0 mg/mL, 3.75 mg/mL, 20.0 mg/mL, 160.0 mg, 80.0 mg, 40.0 mg, 20.0 mg, 10.0 mg, 50.0 mg, 0.1 mg, 40.0 mg/mL
Solution - Oral, Capsule, extended release - Oral, Tablet - Oral, Liquid - Intravenous, Tablet, , Oral, Capsule, extended release, Injection, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Solution - Intravenous, Injection - Intravenous, Solution, Intravenous, Liquid, Injection, solution, Injection, solution - Intravenous
Hemangiomas
, 120.0 mg, 60.0 mg, 2.0 mg/mg, 4.0 mg/mg, 4.28 mg/mL, 1.0 mg/mL, 3.75 mg/mL, 20.0 mg/mL, 160.0 mg, 80.0 mg, 40.0 mg, 20.0 mg, 10.0 mg, 50.0 mg, 0.1 mg, 40.0 mg/mL
Solution - Oral, Capsule, extended release - Oral, Tablet - Oral, Liquid - Intravenous, Tablet, , Oral, Capsule, extended release, Injection, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Solution - Intravenous, Injection - Intravenous, Solution, Intravenous, Liquid, Injection, solution, Injection, solution - Intravenous
Adrenergic Alpha-Antagonists
, 120.0 mg, 60.0 mg, 2.0 mg/mg, 4.0 mg/mg, 4.28 mg/mL, 1.0 mg/mL, 3.75 mg/mL, 20.0 mg/mL, 160.0 mg, 80.0 mg, 40.0 mg, 20.0 mg, 10.0 mg, 50.0 mg, 0.1 mg, 40.0 mg/mL
Solution - Oral, Capsule, extended release - Oral, Tablet - Oral, Liquid - Intravenous, Tablet, , Oral, Capsule, extended release, Injection, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Solution - Intravenous, Injection - Intravenous, Solution, Intravenous, Liquid, Injection, solution, Injection, solution - Intravenous
prophylaxis of migraine headaches
, 120.0 mg, 60.0 mg, 2.0 mg/mg, 4.0 mg/mg, 4.28 mg/mL, 1.0 mg/mL, 3.75 mg/mL, 20.0 mg/mL, 160.0 mg, 80.0 mg, 40.0 mg, 20.0 mg, 10.0 mg, 50.0 mg, 0.1 mg, 40.0 mg/mL
Solution - Oral, Capsule, extended release - Oral, Tablet - Oral, Liquid - Intravenous, Tablet, , Oral, Capsule, extended release, Injection, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Solution - Intravenous, Injection - Intravenous, Solution, Intravenous, Liquid, Injection, solution, Injection, solution - Intravenous
Tremor caused by lithium
, 120.0 mg, 60.0 mg, 2.0 mg/mg, 4.0 mg/mg, 4.28 mg/mL, 1.0 mg/mL, 3.75 mg/mL, 20.0 mg/mL, 160.0 mg, 80.0 mg, 40.0 mg, 20.0 mg, 10.0 mg, 50.0 mg, 0.1 mg, 40.0 mg/mL
Solution - Oral, Capsule, extended release - Oral, Tablet - Oral, Liquid - Intravenous, Tablet, , Oral, Capsule, extended release, Injection, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Solution - Intravenous, Injection - Intravenous, Solution, Intravenous, Liquid, Injection, solution, Injection, solution - Intravenous
Cardiovascular Mortality
, 120.0 mg, 60.0 mg, 2.0 mg/mg, 4.0 mg/mg, 4.28 mg/mL, 1.0 mg/mL, 3.75 mg/mL, 20.0 mg/mL, 160.0 mg, 80.0 mg, 40.0 mg, 20.0 mg, 10.0 mg, 50.0 mg, 0.1 mg, 40.0 mg/mL
Solution - Oral, Capsule, extended release - Oral, Tablet - Oral, Liquid - Intravenous, Tablet, , Oral, Capsule, extended release, Injection, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Solution - Intravenous, Injection - Intravenous, Solution, Intravenous, Liquid, Injection, solution, Injection, solution - Intravenous
Myocardial Infarction
, 120.0 mg, 60.0 mg, 2.0 mg/mg, 4.0 mg/mg, 4.28 mg/mL, 1.0 mg/mL, 3.75 mg/mL, 20.0 mg/mL, 160.0 mg, 80.0 mg, 40.0 mg, 20.0 mg, 10.0 mg, 50.0 mg, 0.1 mg, 40.0 mg/mL
Solution - Oral, Capsule, extended release - Oral, Tablet - Oral, Liquid - Intravenous, Tablet, , Oral, Capsule, extended release, Injection, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Solution - Intravenous, Injection - Intravenous, Solution, Intravenous, Liquid, Injection, solution, Injection, solution - Intravenous
Obstructive Hypertrophic Cardiomyopathy
, 120.0 mg, 60.0 mg, 2.0 mg/mg, 4.0 mg/mg, 4.28 mg/mL, 1.0 mg/mL, 3.75 mg/mL, 20.0 mg/mL, 160.0 mg, 80.0 mg, 40.0 mg, 20.0 mg, 10.0 mg, 50.0 mg, 0.1 mg, 40.0 mg/mL
Solution - Oral, Capsule, extended release - Oral, Tablet - Oral, Liquid - Intravenous, Tablet, , Oral, Capsule, extended release, Injection, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Solution - Intravenous, Injection - Intravenous, Solution, Intravenous, Liquid, Injection, solution, Injection, solution - Intravenous
Thyroid Crisis
, 120.0 mg, 60.0 mg, 2.0 mg/mg, 4.0 mg/mg, 4.28 mg/mL, 1.0 mg/mL, 3.75 mg/mL, 20.0 mg/mL, 160.0 mg, 80.0 mg, 40.0 mg, 20.0 mg, 10.0 mg, 50.0 mg, 0.1 mg, 40.0 mg/mL
Solution - Oral, Capsule, extended release - Oral, Tablet - Oral, Liquid - Intravenous, Tablet, , Oral, Capsule, extended release, Injection, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Solution - Intravenous, Injection - Intravenous, Solution, Intravenous, Liquid, Injection, solution, Injection, solution - Intravenous
Atrial Fibrillation
, 120.0 mg, 60.0 mg, 2.0 mg/mg, 4.0 mg/mg, 4.28 mg/mL, 1.0 mg/mL, 3.75 mg/mL, 20.0 mg/mL, 160.0 mg, 80.0 mg, 40.0 mg, 20.0 mg, 10.0 mg, 50.0 mg, 0.1 mg, 40.0 mg/mL
Solution - Oral, Capsule, extended release - Oral, Tablet - Oral, Liquid - Intravenous, Tablet, , Oral, Capsule, extended release, Injection, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Solution - Intravenous, Injection - Intravenous, Solution, Intravenous, Liquid, Injection, solution, Injection, solution - Intravenous
Tachyarrhythmia caused by Digitalis intoxication
, 120.0 mg, 60.0 mg, 2.0 mg/mg, 4.0 mg/mg, 4.28 mg/mL, 1.0 mg/mL, 3.75 mg/mL, 20.0 mg/mL, 160.0 mg, 80.0 mg, 40.0 mg, 20.0 mg, 10.0 mg, 50.0 mg, 0.1 mg, 40.0 mg/mL
Solution - Oral, Capsule, extended release - Oral, Tablet - Oral, Liquid - Intravenous, Tablet, , Oral, Capsule, extended release, Injection, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Solution - Intravenous, Injection - Intravenous, Solution, Intravenous, Liquid, Injection, solution, Injection, solution - Intravenous
Catecholamines
, 120.0 mg, 60.0 mg, 2.0 mg/mg, 4.0 mg/mg, 4.28 mg/mL, 1.0 mg/mL, 3.75 mg/mL, 20.0 mg/mL, 160.0 mg, 80.0 mg, 40.0 mg, 20.0 mg, 10.0 mg, 50.0 mg, 0.1 mg, 40.0 mg/mL
Solution - Oral, Capsule, extended release - Oral, Tablet - Oral, Liquid - Intravenous, Tablet, , Oral, Capsule, extended release, Injection, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Solution - Intravenous, Injection - Intravenous, Solution, Intravenous, Liquid, Injection, solution, Injection, solution - Intravenous
Ventricular Tachycardia
, 120.0 mg, 60.0 mg, 2.0 mg/mg, 4.0 mg/mg, 4.28 mg/mL, 1.0 mg/mL, 3.75 mg/mL, 20.0 mg/mL, 160.0 mg, 80.0 mg, 40.0 mg, 20.0 mg, 10.0 mg, 50.0 mg, 0.1 mg, 40.0 mg/mL
Solution - Oral, Capsule, extended release - Oral, Tablet - Oral, Liquid - Intravenous, Tablet, , Oral, Capsule, extended release, Injection, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Solution - Intravenous, Injection - Intravenous, Solution, Intravenous, Liquid, Injection, solution, Injection, solution - Intravenous
Chest Pain
, 120.0 mg, 60.0 mg, 2.0 mg/mg, 4.0 mg/mg, 4.28 mg/mL, 1.0 mg/mL, 3.75 mg/mL, 20.0 mg/mL, 160.0 mg, 80.0 mg, 40.0 mg, 20.0 mg, 10.0 mg, 50.0 mg, 0.1 mg, 40.0 mg/mL
Solution - Oral, Capsule, extended release - Oral, Tablet - Oral, Liquid - Intravenous, Tablet, , Oral, Capsule, extended release, Injection, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Solution - Intravenous, Injection - Intravenous, Solution, Intravenous, Liquid, Injection, solution, Injection, solution - Intravenous
Supraventricular Arrhythmias
, 120.0 mg, 60.0 mg, 2.0 mg/mg, 4.0 mg/mg, 4.28 mg/mL, 1.0 mg/mL, 3.75 mg/mL, 20.0 mg/mL, 160.0 mg, 80.0 mg, 40.0 mg, 20.0 mg, 10.0 mg, 50.0 mg, 0.1 mg, 40.0 mg/mL
Solution - Oral, Capsule, extended release - Oral, Tablet - Oral, Liquid - Intravenous, Tablet, , Oral, Capsule, extended release, Injection, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Solution - Intravenous, Injection - Intravenous, Solution, Intravenous, Liquid, Injection, solution, Injection, solution - Intravenous
Coronary Artery Atherosclerosis
, 120.0 mg, 60.0 mg, 2.0 mg/mg, 4.0 mg/mg, 4.28 mg/mL, 1.0 mg/mL, 3.75 mg/mL, 20.0 mg/mL, 160.0 mg, 80.0 mg, 40.0 mg, 20.0 mg, 10.0 mg, 50.0 mg, 0.1 mg, 40.0 mg/mL
Solution - Oral, Capsule, extended release - Oral, Tablet - Oral, Liquid - Intravenous, Tablet, , Oral, Capsule, extended release, Injection, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Solution - Intravenous, Injection - Intravenous, Solution, Intravenous, Liquid, Injection, solution, Injection, solution - Intravenous
Tremor, Essential
, 120.0 mg, 60.0 mg, 2.0 mg/mg, 4.0 mg/mg, 4.28 mg/mL, 1.0 mg/mL, 3.75 mg/mL, 20.0 mg/mL, 160.0 mg, 80.0 mg, 40.0 mg, 20.0 mg, 10.0 mg, 50.0 mg, 0.1 mg, 40.0 mg/mL
Solution - Oral, Capsule, extended release - Oral, Tablet - Oral, Liquid - Intravenous, Tablet, , Oral, Capsule, extended release, Injection, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Solution - Intravenous, Injection - Intravenous, Solution, Intravenous, Liquid, Injection, solution, Injection, solution - Intravenous
Migraine
, 120.0 mg, 60.0 mg, 2.0 mg/mg, 4.0 mg/mg, 4.28 mg/mL, 1.0 mg/mL, 3.75 mg/mL, 20.0 mg/mL, 160.0 mg, 80.0 mg, 40.0 mg, 20.0 mg, 10.0 mg, 50.0 mg, 0.1 mg, 40.0 mg/mL
Solution - Oral, Capsule, extended release - Oral, Tablet - Oral, Liquid - Intravenous, Tablet, , Oral, Capsule, extended release, Injection, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Solution - Intravenous, Injection - Intravenous, Solution, Intravenous, Liquid, Injection, solution, Injection, solution - Intravenous
Warnings
Inderal La has fifteen contraindications and should not be adopted when confronting the conditions presented in the following table.Inderal La ContraindicationsCondition
Risk Level
Notes
Prematurity
Do Not Combine
Asthma
Do Not Combine
second or third degree AV block
Do Not Combine
Shock, Cardiogenic
Do Not Combine
Heart Decompensation
Do Not Combine
Sick Sinus Syndrome
Do Not Combine
Sinus Bradycardia
Do Not Combine
Heart Decompensation
Do Not Combine
Slow Heart Rate
Do Not Combine
Pheochromocytomas
Do Not Combine
Low Blood Pressure
Do Not Combine
Infants Weighing <2kg
Do Not Combine
Bronchospasm
Do Not Combine
Bronchial Asthma
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Propranolol may interact with Toxoplasma Infections
Common Inderal La Drug Interactions
Drug Name
Risk Level
Description
4-Bromo-2,5-dimethoxyphenethylamine
Major
The therapeutic efficacy of 4-Bromo-2,5-dimethoxyphenethylamine can be decreased when used in combination with Propranolol.
4-Methoxyamphetamine
Major
The therapeutic efficacy of 4-Methoxyamphetamine can be decreased when used in combination with Propranolol.
Abediterol
Major
Propranolol may decrease the bronchodilatory activities of Abediterol.
Adrafinil
Major
The therapeutic efficacy of Adrafinil can be decreased when used in combination with Propranolol.
Agrostis gigantea pollen
Major
The risk of a hypersensitivity reaction to Agrostis gigantea pollen is increased when it is combined with Propranolol.
Inderal La Toxicity & Overdose RiskSigns of an overdose of propranolol include low blood pressure, seizures due to low blood sugar, restlessness, and difficulty sleeping. People with asthma may have difficulty breathing. To treat an overdose, medical professionals will monitor vital signs and mental status, and administer fluids to raise blood pressure, atropine to slow an irregular heartbeat, and drugs to open up the airways. If the patient does not respond to fluids, they may be given glucagon followed by drugs that increase the activity of certain hormones. Dialysis usually cannot remove propranolol from the body because it binds strongly to proteins.
Inderal La Novel Uses: Which Conditions Have a Clinical Trial Featuring Inderal La?
249 active studies are currently assessing the potential of Inderal La in providing relief from Migraine, Catecholamine-induced disorders and Hypertensive diseases.Condition
Clinical Trials
Trial Phases
Heart Attack
65 Actively Recruiting
Phase 4, Phase 2, Phase 3, Not Applicable, Phase 1, Early Phase 1
Pheochromocytomas
0 Actively Recruiting
Tachyarrhythmia caused by Digitalis intoxication
0 Actively Recruiting
Hypertensive disease
22 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 4
Thyrotoxicosis
0 Actively Recruiting
Rapid Ventricular Response
0 Actively Recruiting
Atrial Fibrillation
164 Actively Recruiting
Not Applicable, Phase 2, Phase 4, Phase 3, Phase 1
Coronary Artery Atherosclerosis
1 Actively Recruiting
Not Applicable
Supraventricular Arrhythmias
0 Actively Recruiting
Catecholamines
0 Actively Recruiting
Chest Pain
8 Actively Recruiting
Phase 2, Phase 3, Not Applicable, Phase 4
Migraine
55 Actively Recruiting
Not Applicable, Phase 1, Phase 4, Phase 2, Phase 3, Early Phase 1
Tremor, Essential
1 Actively Recruiting
Phase 2
Gastroesophageal variceal hemorrhage prophylaxis
0 Actively Recruiting
Obstructive Hypertrophic Cardiomyopathy
1 Actively Recruiting
Phase 2, Phase 3
Thyroid Crisis
0 Actively Recruiting
Adrenergic Alpha-Antagonists
0 Actively Recruiting
Hemangiomas
0 Actively Recruiting
Proliferating Infantile Hemangioma
0 Actively Recruiting
Tremor caused by lithium
0 Actively Recruiting
Inderal La Reviews: What are patients saying about Inderal La?
5Patient Review
8/26/2013 I've been using Inderal LA for over two decades to manage a head tremor. It's been incredibly effective, but can sometimes be tough to coordinate with my asthma medication.
5Patient Review
10/7/2014 This medication has been great for me. I used to get two migraines a month, but since starting this treatment, I haven't had any at all.
4.7Patient Review
10/19/2009 I was prescribed this medication about 9 years ago for a rapid heartbeat. It worked for several years then had to increase the dose because symptoms returned. Unfortunately, I also experienced EXTREME HAIR LOSS - which is apparently a common side effect of beta blockers (according to my research).
4.7Patient Review
5/15/2011 Since starting this medication a few weeks ago, my migraines have greatly improved. Although I do feel tired the day after taking it.
4.7Patient Review
3/16/2010 This treatment is great! It really helped me and I'm grateful for it.
4.7Patient Review
9/27/20094.3Patient Review
7/22/2015 The drug has been helpful in managing my migraines, though I haven't seen a total prevention of them. The most difficult side effect is an uncontrollable hunger; however, I've found that drinking water and chewing gum helps to alleviate this issue somewhat.
4.3Patient Review
8/3/2013 This medication caused an irregular heart beat for me.
4Patient Review
4/30/2011 I've been using these Inderal tablets for over 15 years to help with my hand tremor. They work well, but I have noticed that if I take them too regularly, they become less effective. I haven't increased the 40mg dose per day because I read on this site that it shouldn't be taken by patients with low blood sugar (which is my case). If anyone could provide clarification on this from a medical standpoint, I would appreciate it.
4Patient Review
11/21/2011 This medication was easy to take and had minimal side effects. My blood pressure lowered significantly, and it also took care of my minor tremors.
3.7Patient Review
1/28/2014 Though this drug is very effective in preventing migraines, the constant tiredness it causes is difficult to manage. I also have trouble working out; if I take the medication before going to the gym, I become nauseous, sweaty and dizzy. Because of these side effects, I stopped taking the drug a couple years ago. However, since my migraines have returned (I average 5 per month), I am reconsidering. Taking magnesium/B2 for several months does not seem to be an effective alternative to prescription drugs.
3Patient Review
3/15/2010 I was recently prescribed Inderal LA 60 mg to take once a day for tremors in my hands that may be caused by taking Zoloft. I have been on the medication for about a month now and I still have shaky hands. I am seeing my doctor soon to find out what is going on, but as of right now, it does not seem like this drug is effective for treating tremors. Has anyone else had a similar experience using this drug?
2.3Patient Review
7/7/2012 The tremors have not gone away and they are still affecting my daily life.
1.3Patient Review
11/4/2011 I experienced some serious side effects after taking this drug for a few years. My blood pressure went down, but I developed impotence and insomnia that didn't go away even after I stopped taking the drug. In 2009, I also developed Peyronie's disease. It's worrying that all of these conditions are rare side effects of this medication.
Patient Q&A Section about inderal la
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What does Inderal LA treat?
"INDICATIONS:
Propranolol HCl is indicated for the treatment of high blood pressure, angina pectoris, and hypertrophic subaortic stenosis. It is also indicated for the prevention of migraine headaches."
Answered by AI
Is propranolol ER the same as Inderal LA?
"HCL
Propanolol HCL ER is used to lower blood pressure and heart rate, making it easier for the heart to pump blood to the rest of the body. It can also be used to prevent [migraine headache](https://www.withpower.com/clinical-trials/migraine-headache)s. Propanolol HCL ER works by relaxing the blood vessels in the brain that cause migraines."
Answered by AI
What is difference between Inderal and Inderal LA?
"There was no significant difference in blood pressure levels between conventional propranolol and 'Inderal' LA, but the mean peak blood level of propranolol was lower with 'Inderal' LA and occurred later."
Answered by AI
What is Inderal LA 60 mg used for?
"This medication is a beta blocker that is used to treat high blood pressure, irregular heartbeats, shaking (tremors), and other conditions as determined by your doctor. It is used after a heart attack to improve survival rates. It is also effective in preventing migraine headaches and chest pain (angina)."
Answered by AI