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What is Inderal La
PropranololThe Generic name of this drug
Treatment SummaryPropranolol is a medication used to treat high blood pressure. It is a combination of two enantiomers, with the S(-)-enantiomer having 100 times the binding affinity for beta adrenergic receptors. Propranolol has been approved by the FDA since 1967 and is used to treat a number of other conditions.
Inderalis the brand name
Inderal La Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Inderal
Propranolol
1967
471
Approved as Treatment by the FDA
Propranolol, also known as Inderal, is approved by the FDA for 5 uses including Obstructive Hypertrophic Cardiomyopathy and Tremor, Essential .Obstructive Hypertrophic Cardiomyopathy
Tremor, Essential
Helps manage Tremor, Essential
Essential Tremor
Helps manage Tremor, Essential
Cardiomyopathy, Hypertrophic
Hypertensive disease
Used to treat High Blood Pressure (Hypertension) in combination with Hydrochlorothiazide
Effectiveness
How Inderal La Affects PatientsPropranolol is a drug used to treat high blood pressure. It can be taken in one or two doses each day and its effects last long. If someone stops taking propranolol suddenly, they may experience chest pain or heart attacks.
How Inderal La works in the bodyPropranolol blocks certain receptors in the body, resulting in decreased blood vessel growth and increased cell death. It also reduces the levels of hormones that regulate blood pressure.
When to interrupt dosage
The measure of Inderal La is contingent upon the identified affliction, including Catecholamines, Hypertensive illness and Hemangiomas. The amount of dosage is contingent upon the method of delivery (e.g. Solution - Oral or Capsule, extended release - Oral) as specified in the table below.Condition
Dosage
Administration
Heart Attack
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Adrenergic Alpha-Antagonists
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Tachyarrhythmia caused by Digitalis intoxication
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Psychomotor Agitation
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Tremor
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Thyrotoxicosis
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Chest Pain
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Supraventricular Arrhythmias
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Hemangioma
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Cardiomyopathy, Hypertrophic
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Proliferating Infantile Hemangioma
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Hypertensive disease
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Performance Anxiety
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Pheochromocytoma
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Ventricular Tachycardia
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Migraine
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Gastroesophageal variceal hemorrhage prophylaxis
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Catecholamines
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Migraine Disorders
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Atrial Fibrillation
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Warnings
Inderal La has fifteen contraindications and should not be adopted when confronting the conditions presented in the following table.Inderal La ContraindicationsCondition
Risk Level
Notes
Heart Decompensation
Do Not Combine
Bronchial Spasm
Do Not Combine
Asthma
Do Not Combine
Infants Weighing <2kg
Do Not Combine
Low Blood Pressure
Do Not Combine
Sick Sinus Syndrome
Do Not Combine
Asthma
Do Not Combine
Pheochromocytoma
Do Not Combine
Atrioventricular Block
Do Not Combine
Slow Heart Rate
Do Not Combine
Shock, Cardiogenic
Do Not Combine
Heart Decompensation
Do Not Combine
Prematurity
Do Not Combine
Sinus Bradycardia
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Propranolol may interact with Pulse Frequency
Common Inderal La Drug Interactions
Drug Name
Risk Level
Description
4-Bromo-2,5-dimethoxyphenethylamine
Major
The therapeutic efficacy of 4-Bromo-2,5-dimethoxyphenethylamine can be decreased when used in combination with Propranolol.
4-Methoxyamphetamine
Major
The therapeutic efficacy of 4-Methoxyamphetamine can be decreased when used in combination with Propranolol.
Abediterol
Major
Propranolol may decrease the bronchodilatory activities of Abediterol.
Adrafinil
Major
The therapeutic efficacy of Adrafinil can be decreased when used in combination with Propranolol.
Agrostis gigantea pollen
Major
The risk of a hypersensitivity reaction to Agrostis gigantea pollen is increased when it is combined with Propranolol.
Inderal La Toxicity & Overdose RiskSigns of an overdose of propranolol include low blood pressure, seizures due to low blood sugar, restlessness, and difficulty sleeping. People with asthma may have difficulty breathing. To treat an overdose, medical professionals will monitor vital signs and mental status, and administer fluids to raise blood pressure, atropine to slow an irregular heartbeat, and drugs to open up the airways. If the patient does not respond to fluids, they may be given glucagon followed by drugs that increase the activity of certain hormones. Dialysis usually cannot remove propranolol from the body because it binds strongly to proteins.
Inderal La Novel Uses: Which Conditions Have a Clinical Trial Featuring Inderal La?
249 active studies are currently assessing the potential of Inderal La in providing relief from Migraine, Catecholamine-induced disorders and Hypertensive diseases.Condition
Clinical Trials
Trial Phases
Atrial Fibrillation
96 Actively Recruiting
Not Applicable, Phase 2, Phase 4, Phase 1, Phase 3, Early Phase 1
Heart Attack
26 Actively Recruiting
Not Applicable, Phase 4, Phase 1, Phase 2, Early Phase 1, Phase 3
Coronary Artery Disease
1 Actively Recruiting
Not Applicable
Chest Pain
2 Actively Recruiting
Not Applicable, Phase 2, Phase 3
Adrenergic Alpha-Antagonists
0 Actively Recruiting
Migraine
54 Actively Recruiting
Phase 4, Not Applicable, Phase 2, Phase 1, Phase 3, Early Phase 1
Hemangioma
0 Actively Recruiting
Gastroesophageal variceal hemorrhage prophylaxis
0 Actively Recruiting
Migraine Disorders
1 Actively Recruiting
Phase 3
Catecholamines
0 Actively Recruiting
Thyroid Crisis
0 Actively Recruiting
Hypertensive disease
23 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3
Pheochromocytoma
0 Actively Recruiting
Thyrotoxicosis
0 Actively Recruiting
Cardiovascular Mortality
0 Actively Recruiting
Myocardial Infarction
0 Actively Recruiting
Tremor
0 Actively Recruiting
Cardiomyopathy, Hypertrophic
0 Actively Recruiting
Proliferating Infantile Hemangioma
0 Actively Recruiting
Psychomotor Agitation
0 Actively Recruiting
Inderal La Reviews: What are patients saying about Inderal La?
5Patient Review
8/26/2013 I've been using Inderal LA for over two decades to manage a head tremor. It's been incredibly effective, but can sometimes be tough to coordinate with my asthma medication.
5Patient Review
10/7/2014 This medication has been great for me. I used to get two migraines a month, but since starting this treatment, I haven't had any at all.
4.7Patient Review
10/19/2009 I was prescribed this medication about 9 years ago for a rapid heartbeat. It worked for several years then had to increase the dose because symptoms returned. Unfortunately, I also experienced EXTREME HAIR LOSS - which is apparently a common side effect of beta blockers (according to my research).
4.7Patient Review
5/15/2011 Since starting this medication a few weeks ago, my migraines have greatly improved. Although I do feel tired the day after taking it.
4.7Patient Review
3/16/2010 This treatment is great! It really helped me and I'm grateful for it.
Patient Q&A Section about inderal la
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What does Inderal LA treat?
"INDICATIONS:
Propranolol HCl is indicated for the treatment of high blood pressure, angina pectoris, and hypertrophic subaortic stenosis. It is also indicated for the prevention of migraine headaches."
Answered by AI
Is propranolol ER the same as Inderal LA?
"HCL
Propanolol HCL ER is used to lower blood pressure and heart rate, making it easier for the heart to pump blood to the rest of the body. It can also be used to prevent migraine headaches. Propanolol HCL ER works by relaxing the blood vessels in the brain that cause migraines."
Answered by AI
What is difference between Inderal and Inderal LA?
"There was no significant difference in blood pressure levels between conventional propranolol and 'Inderal' LA, but the mean peak blood level of propranolol was lower with 'Inderal' LA and occurred later."
Answered by AI
What is Inderal LA 60 mg used for?
"This medication is a beta blocker that is used to treat high blood pressure, irregular heartbeats, shaking (tremors), and other conditions as determined by your doctor. It is used after a heart attack to improve survival rates. It is also effective in preventing migraine headaches and chest pain (angina)."
Answered by AI
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